Suboptimal vitamin D status is a highly prevalent but treatable condition in both hospitalized patients and the general population

Wiley - Tập 19 Số 12 - Trang 642-651 - 2007
Nicole L. Moore1, Gary M. Kiebzak2
1St Luke's Episcopal Hospital, Center for Orthopaedic Research and Education, Orthopaedic Nurse Researcher, Houston, TX 77025, USA.
2St. Luke’s Episcopal Hospital, Center for Orthopaedic Research and Education, Orthopaedic Nurse Researcher, Houston, Texas

Tóm tắt

AbstractPurpose: To heighten awareness of the problems related to the high prevalence of suboptimal vitamin D status in hospitalized patients and the general population, including an overview of vitamin D biology, how vitamin D status is defined, the negative health issues associated with suboptimal vitamin D status, indications for treatment, treatment strategies, and controversies in the field.Data sources: (a) Literature review was performed using PubMed and CINAHL databases to locate and review medical, nursing, and nutritional journals. (b) Authors’ recent prospective studies of 100 patients in a general tertiary hospital rehabilitation unit and 51 nonhospitalized volunteers.Conclusion: Poor vitamin D status (ranging from suboptimal to overt deficiency) is common in both hospitalized patients and ostensibly healthy individuals of all ages and geographic latitude. Suboptimal vitamin D status is associated with muscle weakness, functional deficits, and perhaps longer length of stay of hospitalized patients. Predictors of vitamin D status include race, poor nutrition, advanced age, use of multivitamins, ultraviolet light exposure, and grip strength. Fortunately, treatment with 50,000 IU of vitamin D2 for several weeks is a very inexpensive and safe yet effective treatment to replete vitamin D status.Implications for practice: NPs should be aware of the indications for monitoring vitamin D status and the appropriate treatment for suboptimal vitamin D status. Improving vitamin D status may improve a patient‘s functional ability, therefore decreasing falls and preventing fractures, decreasing length of stay in the hospital, and decreasing the cost of health care. Providers can potentially improve the life of older adults by educating patients on the importance of vitamin D supplementation.

Từ khóa


Tài liệu tham khảo

10.1210/jc.2003-031979

10.1007/s00198-006-0293-9

10.1093/ajcn/80.3.752

10.1038/sj.ejcn.1601759

Dawson‐Hughes B, 2004, Racial/ethic considerations in making recommendations for vitamin D for adult and elderly men and women, American Journal of Clinical Nutrition, 80, 1763S, 10.1093/ajcn/80.6.1763S

10.1007/s00198-005-1867-7

10.1359/jbmr.2002.17.5.891

10.1093/ageing/afh209

10.5694/j.1326-5377.2005.tb06879.x

10.1007/s00198-005-1860-1

10.1007/s002230010085

10.1001/jama.1995.03530210037027

10.1093/ajcn/85.1.6

10.1093/jn/136.4.1126

10.4065/81.3.297

10.1093/ajcn/77.1.204

10.1080/07315724.2003.10719287

10.4065/78.12.1457

10.4065/81.3.353

10.1210/jc.2004-2364

10.1093/jn/135.2.317

10.1093/ajcn/75.4.611

Kiebzak G. M. Moore N. Margolis S. Hollis B. &Kevorkian C. G. (2007).Vitamin D status of patients admitted to a hospital rehabilitation unit: Relationship to function and progress.American Journal of Physical Medicine and Rehabilitation 86(6) 435–445.

10.1067/mpd.2000.109009

10.1007/s00198-005-0042-5

10.1007/BF02555135

10.1007/s001980050162

Morris H. A, 2004, Vitamin D: A hormone for all seasons—How much is enough? Understanding the new pressures, Clinical Biochemist Reviews, 25, 21

10.1111/j.1365-2265.2005.02226.x

10.1093/ajcn/76.1.187

10.4065/78.12.1463

10.1001/archinte.160.8.1199

10.1056/NEJM198904133201506

10.1210/jc.2003-031782

10.1185/030079905X50598

Sizer F., 1994, Nutritional Concepts and Controversies, 222

10.1056/NEJM199803193381201

10.1136/bmj.326.7387.469

10.1093/ajcn/73.2.288

Weaver C. M., 2004, Vitamin D requirements: Current and future, American Journal of Clinical Nutrition, 80, 1734S, 10.1093/ajcn/80.6.1735S

10.1067/mpd.2000.109008

10.1093/jn/135.2.304

10.1016/j.jaad.2005.11.1057

10.1016/S0002-8223(98)00160-6

10.1507/endocrj1954.26.Supplement_65

Zadshir A., 2005, The prevalence of hypovitaminosis D among US adults data from the NHANES III, Ethnicity & Disease, 15, S5‐97‐S5

Thông tin
Thông tin xuất bản

Wiley

Tập 19 Số 12

642-651

Thông tin tác giả