Subject-variability effects on micron particle deposition in human nasal cavities

Alya System, Large Scale Computational Mechanics, 2000. URL: 〈http://www.bsc.es/computer-applications/alya-system〉. ANSYS Meshing User’s Guide, 2000. 〈http://148.204.81.206/Ansys/150/ANSYSMeshingUsersGuide.pdf〉. Asgharian, 2012, A lung dosimetry model of vapor uptake and tissue disposition, Inhalation Toxicology, 24, 182, 10.3109/08958378.2012.654857 Bennett, 2005, Effect of race on fine particle deposition for oral and nasal breathing, Inhalation Toxicology, 17, 641, 10.1080/08958370500188984 Calmet, 2016, Large-scale cfd simulations of the transitional and turbulent regime for the large human airways during rapid inhalation, Computers in Biology and Medicine, 69, 166, 10.1016/j.compbiomed.2015.12.003 Cheng, 1995, Deposition of ultrafine aerosols in the head airways during natural breathing and during simulated breath holding using replicate human upper airway casts, Aerosol Science and Technology, 23, 465, 10.1080/02786829508965329 Cheng, 1996, In vivo measurements of nasal airway dimensions and ultrafine aerosol deposition in the human nasal and oral airways, Journal of Aerosol Science, 27, 785, 10.1016/0021-8502(96)00029-8 Cheng, 2003, Aerosol deposition in the extrathoracic region, Aerosol Science & Technology, 37, 659, 10.1080/02786820300906 Cheng, 2001, Characterization of nasal spray pumps and deposition pattern in a replica of the human nasal airway, Journal of Aerosol Medicine, 14, 267, 10.1089/08942680152484199 Cheng, 1996, Nasal deposition of ultrafine particles in human volunteers and its relationship to airway geometry, Aerosol Science and Technology, 25, 274, 10.1080/02786829608965396 Cheng, 1991, Aerosol deposition in human nasal airway for particles 1nm to 20μm: A model study, Radiation Protection Dosimetry, 38, 41, 10.1093/oxfordjournals.rpd.a081070 Colomés, 2015, Assessment of variational multiscale models for the large eddy simulation of turbulent incompressible flows, Computer Methods in Applied Mechanics and Engineering, 285, 32, 10.1016/j.cma.2014.10.041 Corey, 1998, Normative standards for nasal cross-sectional areas by race as measured by acoustic rhinometry, Otolaryngology-Head and Neck Surgery, 119, 389, 10.1016/S0194-5998(98)70085-3 Corey, 1997, A comparison of the nasal cross-sectional areas and volumes obtained with acoustic rhinometry and magnetic resonance imaging, Otolaryngology-Head and Neck Surgery, 117, 349, 10.1016/S0194-5998(97)70125-6 Corley, 2015, Comparative risks of aldehyde constituents in cigarette smoke using transient computational fluid dynamics/physiologically based pharmacokinetic models of the rat and human respiratory tracts, Toxicological Sciences, 146, 65, 10.1093/toxsci/kfv071 Dastan, 2014, Cfd simulation of total and regional fiber deposition in human nasal cavities, Journal of Aerosol Science, 69, 132, 10.1016/j.jaerosci.2013.12.008 Dhuria, 2010, Intranasal delivery to the central nervous system: Mechanisms and experimental considerations, Journal of Pharmaceutical Sciences, 99, 1654, 10.1002/jps.21924 Doorly, 2008, Nasal architecture: Form and flow, Philosophical Transactions Royal Society A, 366, 3225, 10.1098/rsta.2008.0083 Field, 1988, Laplacian smoothing and delaunay triangulations, Communications in Applied Numerical Methods, 4, 709, 10.1002/cnm.1630040603 Folk, M., Cheng, A., Yates, K., (1999). Hdf5: A file format and i/o library for high performance computing applications. In Proceedings of Supercomputing, volume 99, pp. 5–33. Gambaruto, 2010, Wall shear stress and near-wall convective transport: Comparisons with vascular remodelling in a peripheral graft anastomosis, Journal of Computational Physics, 229, 5339, 10.1016/j.jcp.2010.03.029 Ganser, 1993, A rational approach to drag prediction of spherical and nonspherical particles, Powder Technology, 77, 143, 10.1016/0032-5910(93)80051-B Garcia, 2007, Atrophic rhinitis: A cfd study of air conditioning in the nasal cavity, Journal of Applied Physiology, 103, 1082, 10.1152/japplphysiol.01118.2006 Garcia, 2015, Olfactory deposition of inhaled nanoparticles in humans, Inhalation Toxicology, 27, 394, 10.3109/08958378.2015.1066904 Garcia, 2009, Dosimetry of nasal uptake of water-soluble and reactive gases: A first study of interhuman variability, Inhalation Toxicology, 21, 607, 10.1080/08958370802320186 Garcia, 2009, Interindividual variability in nasal filtration as a function of nasal cavity geometry, Journal of Aerosol Medicine and Pulmonary Drug Delivery, 22, 139, 10.1089/jamp.2008.0713 Ghalati, 2012, Numerical analysis of micro-and nano-particle deposition in a realistic human upper airway, Computers in Biology and Medicine, 42, 39, 10.1016/j.compbiomed.2011.10.005 Golshahi, 2011, In vitro deposition measurement of inhaled micrometer-sized particles in extrathoracic airways of children and adolescents during nose breathing, Journal of Aerosol Science, 42, 474, 10.1016/j.jaerosci.2011.04.002 Golshahi, 2011, In vitro deposition measurement of inhaled micrometer-sized particles in extrathoracic airways of children and adolescents during nose breathing, Journal of Aerosol Science, 42, 474, 10.1016/j.jaerosci.2011.04.002 Guilmette, 1997, Characterising the variability in adult human nasal airway dimensions, The Annals of Occupational Hygiene, 41, 491 Houzeaux, 2011, Extension of fractional step techniques for incompressible flows: The preconditioned orthomin(1) for the pressure schur complement, Computers & Fluids, 44, 297, 10.1016/j.compfluid.2011.01.017 Houzeaux, 2013, Parallel uniform mesh multiplication applied to a navier-stokes solver, Computers & Fluids, 80, 142, 10.1016/j.compfluid.2012.04.017 Houzeaux, 2016, Dynamic load balance applied to particle transport in fluids, International Journal of Computational Fluid Dynamics, 10.1080/10618562.2016.1227070 Houzeaux, 2008, A variational subgrid scale model for transient incompressible flows, International Journal of Computational Fluid Dynamics, 22, 135, 10.1080/10618560701816387 Houzeaux, G., Vázquez, M., (2008). Parallel implementation of a predictor-corrector scheme for the solution of the navier-stokes equations. Hyun, 2001, Computational particle-hemodynamics analysis and geometric reconstruction after carotid endarterectomy, Computers in Biology and Medicine, 31, 365, 10.1016/S0010-4825(01)00007-5 Illum, 2000, Transport of drugs from the nasal cavity to the central nervous system, European Journal of Pharmaceutical Sciences, 11, 1, 10.1016/S0928-0987(00)00087-7 Illum, 2015 Inthavong, 2006, A numerical study of spray particle deposition in a human nasal cavity, Aerosol Science and Technology, 40, 1034, 10.1080/02786820600924978 Inthavong, 2008, Optimising nasal spray parameters for efficient drug delivery using computational fluid dynamics, Computers in Biology and Medicine, 38, 713, 10.1016/j.compbiomed.2008.03.008 Inthavong, 2008, Numerical study of fibre deposition in a human nasal cavity, Journal of Aerosol Science, 39, 253, 10.1016/j.jaerosci.2007.11.007 Kabilan, 2016, Computational fluid dynamics modeling of bacillus anthracis spore deposition in rabbit and human respiratory airways, Journal of Aerosol Science, 99, 64, 10.1016/j.jaerosci.2016.01.011 Karypis, G. Metis: Serial graph partitioning and fill-reducing matrix ordering, 1995–2015. Available at: URL 〈http://glaros.dtc.umn.edu/gkhome/views/metis〉. Keeler, 2016, A computational study of nasal spray deposition pattern in four ethnic groups, Journal of Aerosol Medicine and Pulmonary Drug Delivery, 29, 153, 10.1089/jamp.2014.1205 Kelly, 2004, Particle deposition in human nasal airway replicas manufactured by different methods. part i: Inertial regime particles, Aerosol Science and Technology, 38, 1063, 10.1080/027868290883360 Kelly, 2004, Particle deposition in human nasal airway replicas manufactured by different methods. part i: Inertial regime particles, Aerosol Science and Technology, 38, 1063, 10.1080/027868290883360 Kelly, 2004, Particle deposition in human nasal airway replicas manufactured by different methods. Part ii: Ultrafine particles, Aerosol Science and Technology, 38, 1072, 10.1080/027868290883432 Kesavan, 2000, The relationship between particle deposition in the anterior nasal passage and nasal passage characteristics, Journal of Aerosol Medicine, 13, 17, 10.1089/jam.2000.13.17 Kesavanathan, 1998, The effect of nasal passage characteristics on particle deposition, Journal of Aerosol Medicine, 11, 27, 10.1089/jam.1998.11.27 Kesavanathan, 1998, Human nasal passage particle deposition: The effect of particle size, flow rate, and anatomical factors, Aerosol Science and Technology, 28, 457, 10.1080/02786829808965537 Keyhani, 1997, A numerical model of nasal odorant transport for the analysis of human olfaction, Journal of Theoretical Biology, 186, 279, 10.1006/jtbi.1996.0347 Kim, 2013, Patient specific cfd models of nasal airflow: Overview of methods and challenges, Journal of Biomechanics, 46, 299, 10.1016/j.jbiomech.2012.11.022 Kimbell, 2013, Changes in nasal airflow and heat transfer correlate with symptom improvement after surgery for nasal obstruction, Journal of Biomechanics, 46, 2634, 10.1016/j.jbiomech.2013.08.007 Kimbell, 2007, Characterization of deposition from nasal spray devices using a computational fluid dynamics model of the human nasal passages, Journal of Aerosol Medicine, 20, 59, 10.1089/jam.2006.0531 Kleinstreuer, 2014, Drug-targeting methodologies with applications: A review, World Journal of Clinical Cases, 2, 742, 10.12998/wjcc.v2.i12.742 Kolanjiyil, 2013, Nanoparticle mass transfer from lung airways to systemic regions-part i: Whole-lung aerosol dynamics, Journal of Biomechanical Engineering, 135, 121003, 10.1115/1.4025332 Kolanjiyil, 2016, Computationally efficient analysis of particle transport and deposition in a human whole-lung-airway model. part i: Theory and model validation, Computers in Biology and Medicine, 79, 193, 10.1016/j.compbiomed.2016.10.020 Kolanjiyil, 2016, Computationally efficient analysis of particle transport and deposition in a human whole-lung-airway model. part ii: Dry powder inhaler application, Computers in Biology and Medicine, 84, 247, 10.1016/j.compbiomed.2016.10.025 Leong, 2010, A review of the implications of computational fluid dynamic studies on nasal airflow and physiology, Rhinology, 48, 139 Liu, 2009, Creation of a standardized geometry of the human nasal cavity, Journal of Applied Physiology, 106, 784, 10.1152/japplphysiol.90376.2008 Liu, 2010, Experimental measurements and computational modeling of aerosol deposition in the carleton-civic standardized human nasal cavity, Journal of Aerosol Science, 41, 569, 10.1016/j.jaerosci.2010.02.014 Lohner, 2011, Deflated preconditioned conjugate gradient solvers for the pressure-poisson equation: Extensions and improvements, International Journal of Numerical Methods in Engineering, 87, 2, 10.1002/nme.2932 Menache, 1997, Upper respiratory tract surface areas and volumes of laboratory animals and humans: Considerations for dosimetry models, Journal of Toxicology and Environmental Health, 50, 475, 10.1080/00984109708984003 Mistry, 2009, Nanoparticles for direct nose-to-brain delivery of drugs, International Journal of Pharmaceutics, 379, 146, 10.1016/j.ijpharm.2009.06.019 Morris, 1993, A physiologically based pharmacokinetic model for nasal uptake and metabolism of nonreactive vapors, Toxicology and Applied Pharmacology, 123, 120, 10.1006/taap.1993.1228 Olivares, E., Houzeaux, G., (2016). Time integration schemes comparation for particles transport. In ECCOMAS16, Crete (Greece). Piomelli, 2002, Wall-layer models for large-eddy simulations, Annual Review of Fluid Mechanics, 34, 349, 10.1146/annurev.fluid.34.082901.144919 Rasmussen, 2000, Particle deposition in the nose related to nasal cavity geometry, Rhinology, 38, 102 Rhee, 2011, Toward personalized nasal surgery using computational fluid dynamics, Archives of Facial Plastic Surgery, 13, 305, 10.1001/archfacial.2011.18 Robinson, 1991, Coherent motions in the turbulent boundary layer, Annual Review of Fluid Mechanics, 23, 601, 10.1146/annurev.fl.23.010191.003125 Schroeter, 2010, A computational fluid dynamics approach to assess interhuman variability in hydrogen sulfide nasal dosimetry, Inhalation Toxicology, 22, 277, 10.3109/08958370903278077 Schroeter, 2011, Effects of surface smoothness on inertial particle deposition in human nasal models, Journal of Aerosol Science, 42, 52, 10.1016/j.jaerosci.2010.11.002 Schroeter, 2006, Analysis of particle deposition in the turbinate and olfactory regions using a human nasal computational fluid dynamics model, Journal of Aerosol Medicine, 19, 301, 10.1089/jam.2006.19.301 Schroeter, 2015, Experimental measurements and computational predictions of regional particle deposition in a sectional nasal model, Journal of Aerosol Medicine and Pulmonary Drug Delivery, 28, 20, 10.1089/jamp.2013.1084 Schroeter, 2015, Experimental measurements and computational predictions of regional particle deposition in a sectional nasal model, Journal of Aerosol Medicine and Pulmonary Drug Delivery, 28, 20, 10.1089/jamp.2013.1084 Schroete, 2008, Application of physiological computational fluid dynamics models to predict interspecies nasal dosimetry of inhaled acrolein, Inhalation Toxicology, 20, 227, 10.1080/08958370701864235 Segal, 2008, Effects of differences in nasal anatomy on airflow distribution: A comparison of four individuals at rest, Annals of Biomedical Engineering, 36, 1870, 10.1007/s10439-008-9556-2 Shanley, 2008, Numerical simulations investigating the regional and overall deposition efficiency of the human nasal cavity, Inhalation Toxicology, 20, 1093, 10.1080/08958370802130379 Shi, 2007 Shi, 2007, Modeling of inertial particle transport and deposition in human nasal cavities with wall roughness, Journal of Aerosol Science, 38, 398, 10.1016/j.jaerosci.2007.02.002 Shi, 2007, Modeling of inertial particle transport and deposition in human nasal cavities with wall roughness, Journal of Aerosol Science, 38, 398, 10.1016/j.jaerosci.2007.02.002 Shi, 2008, Dilute suspension flow with nanoparticle deposition in a representative nasal airway model, Physics of Fluids, 20, 013301, 10.1063/1.2833468 Shi, 2008, Dilute suspension flow with nanoparticle deposition in a representative nasal airway model, Physics of Fluids, 20, 013301, 10.1063/1.2833468 Soto, 2003, A linelet preconditioner for incompressible flow solvers, International Journal of Numerical Methods for Heat & Fluid Flow, 13, 133, 10.1108/09615530310456796 Storey-Bishoff, 2008, Deposition of micrometer-sized aerosol particles in infant nasal airway replicas, Journal of Aerosol Science, 39, 1055, 10.1016/j.jaerosci.2008.07.011 Thorne, 1995, Quantitative analysis of the olfactory pathway for drug delivery to the brain, Brain Research, 692, 278, 10.1016/0006-8993(95)00637-6 Thorne, 2004, Delivery of insulin-like growth factor-i to the rat brain and spinal cord along olfactory and trigeminal pathways following intranasal administration, Neuroscience, 127, 481, 10.1016/j.neuroscience.2004.05.029 Wang, 2008, Fibrous particle deposition in human nasal passage: The influence of particle length, flow rate, and geometry of nasal airway, Journal of Aerosol Science, 39, 1040, 10.1016/j.jaerosci.2008.07.008 Wiesmiller, 2003, The impact of expiration on particle deposition within the nasal cavity, Clinical Otolaryngology & Allied Sciences, 28, 304, 10.1046/j.1365-2273.2003.00707.x Xi, 2016, Modeling of inertial deposition in scaled models of rat and human nasal airways: Towards in vitro regional dosimetry in small animals, Journal of Aerosol Science, 99, 78, 10.1016/j.jaerosci.2016.01.013 Xi, 2008, Numerical predictions of submicrometer aerosol deposition in the nasal cavity using a novel drift flux approach, International Journal of Heat and Mass Transfer, 51, 5562, 10.1016/j.ijheatmasstransfer.2008.04.037 Zhang, 2011, Computational analysis of airflow and nanoparticle deposition in a combined nasaloraltracheobronchial airway model, Journal of Aerosol Science, 42, 174, 10.1016/j.jaerosci.2011.01.001 Zwartz, 2001, Effect of flow rate on particle deposition in a replica of a human nasal airway, Inhalation Toxicology, 13, 109, 10.1080/089583701300001050