Subcutaneous bioavailability of therapeutic antibodies as a function of FcRn binding affinity in mice

mAbs - Tập 4 Số 1 - Trang 101-109 - 2012
Rong Deng1,2,3, Y. Gloria Meng4,2,3, Kwame Hoyte4,2,3, Jeff Lutman1,2,3, Yanmei Lu4,2,3, Suhasini Iyer1,2,3, Laura DeForge4,2,3, Frank‐Peter Theil1,2,3, Paul J. Fielder1,2,3, Saileta Prabhu1,2,3
1Department of Pharmacokinetic and Pharmacodynamic Sciences
2Genentech, Inc.
3South San Francisco, CA USA
4Department of Assay & Automation Technology

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