Subcellular localization and regulation of GABAA receptors and associated proteins
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Abddle, 1999, Relationships between trait and state anxiety and the central benzodiazepine receptor: A PET study, Eur.J Neurosci., 11, 1470, 10.1046/j.1460-9568.1999.00556.x
Allison, 2000, Postsynaptic scaffolds of excitatory and inhibitory synapses in hippocampal neurons: Maintenance of core components independent of actin filaments and microtubules, J. Neurosci., 20, 4545, 10.1523/JNEUROSCI.20-12-04545.2000
Baer, 2000, Rescue of γ2 subunit-deficient mice by transgenic overexpression of the GABAA receptor γ2S or γ2L subunit isoforms, Eur. J. Neurosci., 12, 2639, 10.1046/j.1460-9568.2000.00159.x
Baer, 1999, Postsynaptic clustering of GABAA receptors by the γ3 subunit in vivo, 96, 12860
Barnard, 1998, International Union of Pharmacology. XV. Subtypes of gamma-aminobutyric acidA receptors: Classification on the basis of subunit structure and receptor function, Pharmacol. Rev., 50, 291
Bechade, 1996, Expression of glycine receptor alpha subunits and gephyrin in cultured spinal neurons, Eur. J. Neurosci., 8, 429, 10.1111/j.1460-9568.1996.tb01226.x
Bedford, 2000, GRUB1 regulates the cell surface stability of GABAA receptors, Eur.J Neurosci., 12, 43
Benke, 1996, GABAA receptor subtypes differentiated by their γ-subunit variants: Prevalence, pharmacology and subunit architecture, Neuropharmacology, 35, 1413, 10.1016/S0028-3908(96)00068-8
Betz, 1991, How to build a glycinergic postsynaptic membrane, J. Cell Sci. Suppl., 15, 23, 10.1242/jcs.1991.Supplement_15.4
Bhargavi, 1998, Phosphatidylinositol 3-kinase binds to profilin through the p85 a subunit and regulates cytoskeletal assembly, Biochem. Mol. Biol. Int., 46, 241
Bishop, 2000, Rho GTPases and their effector proteins, Biochem J., 348, 241, 10.1042/0264-6021:3480241
Bohlhalter, 1994, Inhibitory neurotransmission in rat spinal cord: Co-localization of glycine- and GABAA-receptors at GABAergic synaptic contacts demonstrated by triple immunofluorescence staining, Brain Res., 642, 59, 10.1016/0006-8993(94)90905-9
Bonnert, 1999, Theta, a novel gamma-aminobutyric acid type A receptor subunit, 96, 9891
Bormann, 2000, The “ABC” of GABA receptors, Trends Pharmacol. Sci., 21, 16, 10.1016/S0165-6147(99)01413-3
Bouilleret, 2000, Early loss of interneurons and delayed subunit-specific changes in GABAA-receptor expression in a mouse model of mesial temporal lobe epilepsy, Hippocampus, 10, 305, 10.1002/1098-1063(2000)10:3<305::AID-HIPO11>3.0.CO;2-I
Brandon, 1999, Subunit-specific association of protein kinase C and the receptor for activated C kinase with GABA type A receptors, J. Neurosci., 19, 9228, 10.1523/JNEUROSCI.19-21-09228.1999
Brandon, 1999, Regulation of GABAA receptors by phosphorylation and associated proteins, Soc. Neurosci. Abstr., 25, 967
Brickley, 1996, Development of a tonic form of synaptic inhibition in rat cerebellar granule cells resulting from persistent activation of GABAA receptors, J. Physiol. (Lond.), 497, 753, 10.1113/jphysiol.1996.sp021806
Brooks-Kayal, 1998, Selective changes in single cell GABAA receptor subunit expression and function in temporal lobe epilepsy, Nature Med., 4, 1166, 10.1038/2661
Brown, 1998, Gamma-aminobutyric acidA receptor function is desensitised in rat cultured cerebellar granule cells following chronic flunitrazepam treatment, J. Neurochem., 71, 1232, 10.1046/j.1471-4159.1998.71031232.x
Brünig, 2001, BDNF reduces miniature inhibitory postsynaptic currents by rapid downregulation of GABAA receptor surface expression, Eur. J. Neurosci., 13, 1320, 10.1046/j.0953-816x.2001.01506.x
Brussaard, 1997, Plasticity in fast synaptic inhibition of adult oxytocin neurons caused by switch in GABAA receptor subunit expression, Neuron, 19, 1103, 10.1016/S0896-6273(00)80401-8
Buhl, 1994, Physiological properties of anatomically identified axo-axonic cells in the rat hippocampus, J. Neurophysiol., 71, 1289, 10.1152/jn.1994.71.4.1289
Buhl, 1996, Zinc-induced collapse of augmented inhibition by GABA in a temporal lobe epilepsy model, Science, 271, 369, 10.1126/science.271.5247.369
Cabot, 1995, Postsynaptic gephyrin immunoreactivity exhibits a nearly one-to-one correspondence with γ-aminobutyric acid-like immunogold-labeled synaptic inputs to sympathetic preganglionic neurons, J. Comp. Neurol., 356, 418, 10.1002/cne.903560309
Carlier, 1997, Control of actin dynamics in cell motility, J. Mol. Biol., 269, 459, 10.1006/jmbi.1997.1062
Chebib, 2000, GABA-activated ligand gated ion channels: Medicinal chemistry and molecular biology, J. Med. Chem., 43, 1427, 10.1021/jm9904349
Chen, 2000, The gamma-aminobutyric acid type A (GABAA) receptor-associated protein (GABARAP) promotes GABAA receptor clustering and modulates the channel kinetics, 97, 11557
Chen, 1993, Colocalization of neurotransmitters in the deep cerebellar nuclei, J. Neurocytol., 22, 81, 10.1007/BF01181572
Colledge, 1998, Signals mediating ion channel clustering at the neuromuscular junction, Curr Opin. Neurobiol., 8, 357, 10.1016/S0959-4388(98)80061-5
Connolly, 1999, Cell surface stability of γ-aminobutyric acid type A receptors: Dependence on protein kinase C activity and subunit composition, J. Biol. Chem., 274, 36565, 10.1074/jbc.274.51.36565
Connolly, 1996, Assembly and cell surface expression of heteromeric and homomeric γ-aminobutyric acid type A receptors, J. Biol. Chem., 271, 89, 10.1074/jbc.271.1.89
Craig, 1996, Clustering of gephyrin at GABAergic but not glutamatergic synapses in cultured rat hippocampal neurons, J. Neurosci., 16, 3166, 10.1523/JNEUROSCI.16-10-03166.1996
Craig, 1994, Selective clustering of glutamate and γ-aminobutyric acid receptors opposite terminals releasing the corresponding neurotransmitters, 91, 12373
Crestani, 1999, Decreased GABAA-receptor clustering results in enhanced anxiety and a bias for threat cues, Nat. Neurosci., 2, 833, 10.1038/12207
Davies, 1997, Insensitivity to anaesthetic agents conferred by a class of GABAA receptor subunit, Nature, 385, 820, 10.1038/385820a0
DeLorey, 1998, Mice lacking the beta3 subunit of the GABAA receptor have the epilepsy phenotype and many of the behavioral characteristics of Angelman syndrome, J. Neurosci., 18, 8505, 10.1523/JNEUROSCI.18-20-08505.1998
Devor, 2000, Non-homogeneous distribution of GABAA receptors in the inferior olivary nucleus revealed by electrophysiology and immunocytochemistry, Eur. J. Neurosci., 12, 141
Enz, 1999, GABAC receptor rho subunits are heterogeneously expressed in the human CNS and form homo- and heterooligomers with distinct physical properties, Eur J Neurosci., 11, 41, 10.1046/j.1460-9568.1999.00423.x
Essrich, 1998, Postsynaptic clustering of major GABAA receptor subtypes requires the γ2 subunit and gephyrin, Nat. Neurosci., 1, 563, 10.1038/2798
Fagiolini, 2000, Inhibitory threshold for critical-period activation in primary visual cortex, Nature, 404, 183, 10.1038/35004582
Feng, 1998, Dual requirement for gephyrin in glycine receptor clustering and molybdoenzyme activity, Science, 282, 1321, 10.1126/science.282.5392.1321
Fischer, 2000, Reduced synaptic clustering of GABA and glycine receptors in the retina of the gephyrin null mutant mouse, J. Comp. Neurol., 427, 634, 10.1002/1096-9861(20001127)427:4<634::AID-CNE10>3.0.CO;2-X
Frazier, 1997, Actin cytoskeleton: Are FH proteins local organizers?, Curr. Biol., 7, R414, 10.1016/S0960-9822(06)00205-3
Fritschy, 1995, GABAA receptor heterogeneity in the adult rat brain: Differential regional and cellular distribution of seven major subunits, J. Comp. Neurol., 359, 154, 10.1002/cne.903590111
Fritschy, 1998, Synapse-specific localization of NMDA- and GABAA-receptor subunits revealed by antigen-retrieval immunohistochemistry, J. Comp. Neurol., 390, 194, 10.1002/(SICI)1096-9861(19980112)390:2<194::AID-CNE3>3.0.CO;2-X
Fuhrmann, 2000, Identification of novel gephyrin-binding proteins, Eur.J Neurosci., 12, 363
Gardiol, 1999, Dendritic and postsynaptic protein synthetic machinery, J. Neurosci., 19, 168, 10.1523/JNEUROSCI.19-01-00168.1999
Gertler, 1996, Mena, a relative of VASP and Drosophila Enabled, is implicated in the control of microfilament dynamics, Cell, 87, 227, 10.1016/S0092-8674(00)81341-0
Gieselmann, 1995, Distinct biochemical characteristics of the two human profilin isoforms, Eur. J. Biochem., 229, 621, 10.1111/j.1432-1033.1995.tb20506.x
Giusetto, 1998, Localization of the clustering protein gephyrin at GABAergic synapses in the main olfactory bulb of the rat, J. Comp. Neurol., 395, 231, 10.1002/(SICI)1096-9861(19980601)395:2<231::AID-CNE7>3.0.CO;2-3
Goldman, 1998, Molecular mechanisms mediating synapse-specific gene expression during development of the neuromuscular junction, Can. J. Appl. Physiol., 23, 390, 10.1139/h98-023
Gorrie, 1997, Assembly of GABAA receptors composed of α1 and β2 subunits in both neurons and fibroblasts, J. Neurosci., 17, 6587, 10.1523/JNEUROSCI.17-17-06587.1997
Gray, 1959, Axosomatic and axodendritic synapses of the cerebral cortex: An electron microscopic study, J. Anat. (Lond.), 93, 420
Grünert, 1993, Immunocytochemical localization of glycine receptors in the mammalian retina, J. Comp. Neurol., 335, 523, 10.1002/cne.903350405
Günther, 1995, Benzodiazepine-insensitive mice generated by targeted disruption of the γ2 subunit gene of GABAA receptors, 92, 7749
Gutierrez, 1994, Immunocytochemical localization of γ2 short and γ2 long subunits of the GABAA receptor in the rat brain, J. Neurosci., 14, 7168, 10.1523/JNEUROSCI.14-11-07168.1994
Gutsche-Perelroizen, 1999, Filament assembly from profilin-actin, J. Biol. Chem., 274, 6234, 10.1074/jbc.274.10.6234
Hanley, 1999, The protein MAP-1B links GABA(C) receptors to the cytoskeleton at retinal synapses, Nature, 397, 66, 10.1038/16258
Harlan, 1994, Pleckstrin homology domains bind to phosphatidylinositol-4,5-bisphosphate, Nature, 371, 168, 10.1038/371168a0
hartwig, 1989, Association of profilin with filament-free regions of human leukocyte and platelet membranes and reversible membrane binding during platelet activation, J. Cell Biol., 109, 1571, 10.1083/jcb.109.4.1571
Hensch, 1998, Local GABA circuit control of experience-dependent plasticity in developing visual cortex, Science, 282, 1504, 10.1126/science.282.5393.1504
Herb, 1992, The third γ subunit of the γ-aminobutyric acid type A receptor family, 89, 1433
Hering, 1996, Formation of synaptic specializations in the inner plexiform layer of the developing chick retina, J. Comp. Neurol., 375, 393, 10.1002/(SICI)1096-9861(19961118)375:3<393::AID-CNE4>3.0.CO;2-Y
Hevers, 1998, The diversity of GABAA receptors. Pharmacological and electrophysiological properties of GABAA channel subtypes, Mol. Neurobiol., 18, 35, 10.1007/BF02741459
Hoch, 1999, Formation of the neuromuscular junction: Agrin and its unusual receptors, Eur. J Biochem., 265, 1, 10.1046/j.1432-1327.1999.00765.x
Homanics, 1999, Normal electrophysiological and behavioral responses to ethanol in mice lacking the long splice variant of the γ2 subunit of the γ-aminobutyrate type A receptor, Neuropharmacology, 38, 253, 10.1016/S0028-3908(98)00177-4
Honore, 1993, Cloning and expression of a novel human profilin variant, profilin II, FEBS Lett., 330, 151, 10.1016/0014-5793(93)80262-S
Huntsman, 1999, Reciprocal inhibitory connections and network synchrony in the mammalian thalamus, Science, 283, 541, 10.1126/science.283.5401.541
Husi, 2000, Proteomic analysis of NMDA receptor-adhesion protein signaling complexes, Nat. Neurosci., 3, 661, 10.1038/76615
Imamura, 1997, Bnilp and Bnrlp: Downstream targets of the Rho family small G-proteins which interact with profilin and regulate actin cytoskeleton in Saccharomyces cerevisiae, EMBO J., 16, 2745, 10.1093/emboj/16.10.2745
Irie, 1997, Binding of neuroligins to PSD-95, Science, 277, 1511, 10.1126/science.277.5331.1511
Johnston, 1998, Flunitrazepam rapidly reduces GABA(A) receptor subunit protein expression via a protein kinase C-dependent mechanism, Br. J. Pharmacol., 124, 1338, 10.1038/sj.bjp.0702012
Jonas, 1998, Corelease of two fast neurotransmitters at a central synapse, Science, 281, 419, 10.1126/science.281.5375.419
Jones, 1997, Ligand-gated ion channel subunit partnership: GABAA receptor α6 subunit gene inactivation inhibits δ subunit expression, J. Neurosci., 17, 1350, 10.1523/JNEUROSCI.17-04-01350.1997
Joneson, 1996, RAC regulation of actin polymerization and proliferation by a pathway distinct from Jun kinase, Science, 274, 1374, 10.1126/science.274.5291.1374
Kannenberg, 1997, Proteins associated with α1-subunit-containing GABAA receptors from bovine brain, J. Neurochem., 68, 1352, 10.1046/j.1471-4159.1997.68041352.x
Kannenberg, 1999, A novel serine kinase with specificity for β3-subunts is tightly associated with GABA(A) receptors, J. Biol. Chem., 274, 21257, 10.1074/jbc.274.30.21257
King, 2000, The dynein microtubule motor, Biochim. Biophys. Acta, 1496, 60, 10.1016/S0167-4889(00)00009-4
Kins, 2000, Collybistin, a newly identified brain-specific GEF, induces submembrane clustering of gephyrin, Nat. Neurosci., 3, 22, 10.1038/71096
Kirsch, 1993, Widespread expression of gephyrin, a putative glycine receptor-tubulin linker protein, in rat brain, Brain Res., 621, 301, 10.1016/0006-8993(93)90120-C
Kirsch, 1998, Glycine-receptor activation is required for receptor clustering in spinal neurons, Nature, 392, 717, 10.1038/33694
Kirsch, 1995, The postsynaptic localization of the glycine receptor-associated protein gephyrin is regulated by the cytoskeleton, J. Neurosci., 15, 4148, 10.1523/JNEUROSCI.15-06-04148.1995
Kirsch, 1991, The 93-kDa glycine receptor-associated protein binds to tubulin, J. Biol. Chem., 266, 22242, 10.1016/S0021-9258(18)54560-9
Kirsch, 1993, Distribution of gephyrin transcripts in the adult and developing rat brain, Eur. J. Neurosci., 5, 1109, 10.1111/j.1460-9568.1993.tb00965.x
Kirsch, 1993, Gephyrin antisense oligonucleotides prevent glycine receptor clustering in spinal neurons, Nature, 366, 745, 10.1038/366745a0
Kneussel, 1999, Loss of postsynaptic GABA(A) receptor clustering in gephyrin-deficient mice, J. Neurosci., 19, 9289, 10.1523/JNEUROSCI.19-21-09289.1999
Kneussel, 2000, The gamma-aminobutyric acid type A receptor (GABAAR)-associated protein GABARAP interacts with gephyrin but is not involved in receptor anchoring at the synapse, 97, 8594
Knoflach, 1991, The γ3-subunit of the GABAA-receptor confers sensitivity to benzodiazepine receptor ligands, FEBS Lett., 293, 191, 10.1016/0014-5793(91)81184-A
Knuesel, 1999, Short communication: Altered synaptic clustering of GABAA receptors in mice lacking dystrophin (mdx mice), Eur. J. Neurosci., 11, 4457, 10.1046/j.1460-9568.1999.00887.x
Knuesel, 2000, Alterations in dystrophin and utrophin expression parallel the reorganization of GABAergic synapses in a mouse model of temporal lobe epilepsy, Eur. J Neurosci., 13, 1113, 10.1046/j.0953-816x.2001.01476.x
Koulen, 1998, Synaptic clustering of GABA(C) receptor rho-subunts in the rat retina, Eur. J. Neurosci., 10, 115, 10.1046/j.1460-9568.1998.00005.x
Kozma, 1995, The Ras-related protein Cdc42Hs and bradykinin promote formation of peripheral actin microspikes and filopodia in Swiss 3T3 fibroblasts, Mol. Cell. Biol., 15, 1942, 10.1128/MCB.15.4.1942
Lambrechts, 1997, The mammalian profilin isoforms display complementary affinities for PIP2 and proline-rich sequences, EMBO J., 16, 484, 10.1093/emboj/16.3.484
Laurie, 1992, The distribution of 13 GABAA receptor subunit mRNAs in the rat brain. II. Olfactory bulb and cerebellum, J. Neurosci., 12, 1063, 10.1523/JNEUROSCI.12-03-01063.1992
Lemmon, 1996, PH domains: Diverse sequences with a common fold recruit signaling molecules to the cell surface, Cell, 85, 621, 10.1016/S0092-8674(00)81022-3
Levi, 1999, Synaptic control of glycine and GABAA receptors and gephyrin expression in cultured neurons, J. Neurosci., 19, 7434, 10.1523/JNEUROSCI.19-17-07434.1999
Levi, 1998, Strychnine-sensitive stabilization of postsynaptic glycine receptor clusters, J. Cell Sci., 111, 335, 10.1242/jcs.111.3.335
Liu, 2000, Direct protein-protein coupling enables cross-talk between dopamine D5 and gamma-aminobutyric acid A receptors, Nature, 403, 274, 10.1038/35001232
Loup, 2000, Selective alterations in GABAA receptor subtypes in human temporal lobe epilepsy, J. Neurosci., 20, 5401, 10.1523/JNEUROSCI.20-14-05401.2000
Lu, 1996, Lipid products of phosphoinositide 3-kinase bind human profilin with high affinity, Biochemistry, 35, 14027, 10.1021/bi961878z
Lüscher, 1997, Neuronal subtype-specific expression directed by the GABAA receptor δ subunit gene promoter in transgenic mice and in cultured cells, Mol. Brain Res., 51, 197, 10.1016/S0169-328X(97)00242-8
MacDermott, 1999, Presynaptic ionotropic receptors and the control of transmitter release, Annu. Rev. Neurosci., 22, 443, 10.1146/annurev.neuro.22.1.443
Macdonald, 1994, GABAA receptor channels, Annu. Rev. Neurosci., 17, 569, 10.1146/annurev.ne.17.030194.003033
Malherbe, 1990, GABAA-receptor expressed from rat brain alpha- and beta-subunit cDNAs displays potentiation by benzodiazepine receptor ligands, Mol. Brain Res., 8, 199, 10.1016/0169-328X(90)90017-8
Malosio, 1991, Widespread expression of glycine receptor subunit mRNAs in the adult and developing rat brain, EMBO J., 10, 2401, 10.1002/j.1460-2075.1991.tb07779.x
Mammoto, 1998, Interactions of drebrin and gephyrin with profilin, Biochem. Biophys. Res. Commun., 243, 86, 10.1006/bbrc.1997.8068
Mann, 1994, Molecular characterization of light chain 3, J. Biol. Chem., 269, 1149, 10.1016/S0021-9258(19)78150-2
McDonald, 1994, Differential phosphorylation of intracellular domains of γ-aminobutyric acid type A receptor subunits by calcium/calmodulin type 2-dependent protein kinase and cGMP-dependent protein kinase, J. Biol. Chem., 269, 18111, 10.1016/S0021-9258(17)32424-9
Meyer, 2000, Regulation of somatodendritic GABAA receptor channels in rat hippocampal neurons: evidence for a role of the small GTPase Rac1, J. Neurosci., 10.1523/JNEUROSCI.20-18-06743.2000
Meyer, 1995, Identification of a gephyrin binding motif on the glycine receptor β subunit, Neuron, 15, 563, 10.1016/0896-6273(95)90145-0
Mihalek, 1999, Attenuated sensitivity to neuroactive steroids in gamma-aminobutyrate type A receptor delta subunit knockout mice, 96, 12905
Miralles, 1994, Differential expression of the short and long forms of the γ2 subunit of the GABAA/benzodiazepine receptors, Brain Res. Mol. Brain Res., 24, 129, 10.1016/0169-328X(94)90124-4
Mohler, 1996, The GABAA receptors: From subunits to diverse functions, 89
Mohler, 1998, GABAA-receptor assembly in vivo—Lessons from subunit mutant mice, Life Sci., 62, 1611, 10.1016/S0024-3205(98)00116-7
Moss, 1992, Identification of the cAMP-dependent protein kinase and protein kinase C phosphorylation sites within the major intracellular loop domains of the β1 γ2S and γ2L subunits of the γ-aminobutyric acid type A receptor, J. Biol. Chem., 267, 14470, 10.1016/S0021-9258(19)49736-6
Moss, 1996, Modulation of amino acid-gated ion channels by protein phosphorylation, Int. Rev. Neurobiol., 39, 1, 10.1016/S0074-7742(08)60662-5
Naisbitt, 2000, Interaction of the postsynaptic density-95/guanylate kinase domainassociated protein complex with a light chain of myosin-V and dynein, J. Neurosci., 20, 4524, 10.1523/JNEUROSCI.20-12-04524.2000
Newton, 1996, Protein kinase C: Ports of anchor in the cell, Curr. Biol., 6, 806, 10.1016/S0960-9822(02)00600-0
Nobes, 1995, Rho, rac, and cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia, Cell, 81, 53, 10.1016/0092-8674(95)90370-4
Nusser, 1998, Increased number of synaptic GABAA receptors underlies potentiation at hippocampal inhibitory synapses, Nature, 395, 172, 10.1038/25999
Nusser, 1995, Relative densities of synaptic and extrasynaptic GABAA receptors on cerebellar granule cells as determined by a quantitative immunogold method, J. Neurosci., 15, 2948, 10.1523/JNEUROSCI.15-04-02948.1995
Nusser, 1996, Differential synaptic localization of two major γ-aminobutyric acid type A receptor α subunits on hippocampal pyramidal cells, 93, 11939
Nusser, 1998, Segregation of different GABAA receptors to synaptic and extrasynaptic membranes of cerebellar granule cells, J. Neurosci., 18, 1693, 10.1523/JNEUROSCI.18-05-01693.1998
O'Brien, 1999, Synaptic clustering of AMPA receptors by the extracellular immediate-early gene product Narp, Neuron, 23, 309, 10.1016/S0896-6273(00)80782-5
Ottersen, 1988, Colocalization of glycine-like and GABA-like immunoreactivities in Golgi cell terminals in the rat cerebellum: a postembedding light and electron microscopic study, Brain Res., 450, 342, 10.1016/0006-8993(88)91573-9
Paulsen, 1998, A model of hippocampal memory encoding and retrieval: GABAergic control of synaptic plasicity, Trends Neurosci., 21, 273, 10.1016/S0166-2236(97)01205-8
Penschuck, 1999, Activity-dependent regulation of GABAA receptors, Ann. NY Acad. Sci., 868, 654, 10.1111/j.1749-6632.1999.tb11342.x
Persohn, 1992, Comparative molecular neuroanatomy of cloned GABAA receptor subunits in the rat CNS, J. Comp. Neurol., 326, 193, 10.1002/cne.903260204
Pfeiffer, 1984, Monoclonal antibodies and peptide mapping reveal structural similarities between the subunits of the glycine receptor of rat spinal cord, 81, 7224
Poulter, 1993, Co-existent expression of GABAA receptor β2, β3 and γ2 subunit messenger RNAs during embryogenesis and early postnatal development of the rat central nervous system, Neuroscience, 53, 1019, 10.1016/0306-4522(93)90486-Y
Pourcho, 1991, Glycine receptor immunoreactivity is localized at amacrine synapses in cat retina, Vis. Neurosci., 7, 611, 10.1017/S0952523800010397
Prior, 1992, Primary structure and alternative splice variants of gephyrin, a putative glycine receptor-tubulin linker protein, Neuron, 8, 1161, 10.1016/0896-6273(92)90136-2
Pritchett, 1988, Transient expression shows ligand gating and allosteric potentiation of GABAA receptor subunits, Science, 242, 1306, 10.1126/science.2848320
Puia, 1991, Influence of recombinant gamma-aminobutyric acid-A receptor subunit composition on the action of allosteric modulators of gamma-aminobutyric acid-gated Cl-currents, Mol. Pharmacol., 39, 691
Racca, 1997, Dendritic and postsynaptic localizations of glycine receptor ot subunit mRNAs, J. Neurosci., 17, 1691, 10.1523/JNEUROSCI.17-05-01691.1997
Rao, 2000, Mismatched appositions of presynaptic and postsynaptic components in isolated hippocampal neurons, J. Neurosci., 20, 8344, 10.1523/JNEUROSCI.20-22-08344.2000
Reid, 1999, Identification and characterization of hPEM-2, a guanine nucleotide exchange factor specific for Cdc42, J. Biol. Chem., 274, 33587, 10.1074/jbc.274.47.33587
Reinhard, 1995, The proline-rich focal adhesion and microfilament protein VASP is a ligand for profilins, EMBO J., 14, 1583, 10.1002/j.1460-2075.1995.tb07146.x
Ruegg, 1998, Agrin orchestrates synaptic differentiation at the vertebrate neuromuscular junction, Trends Neurosci., 21, 22, 10.1016/S0166-2236(97)01154-5
Rutherford, 1997, Brain-derived neurotrophic factor mediates the activity-dependent regulation of inhibition in neocortical cultures, J. Neurosci., 17, 4527, 10.1523/JNEUROSCI.17-12-04527.1997
Sabatini, 1999, Interaction of RAFT1 with gephyrin required for rapamycin-sensitive signaling, Science, 284, 1161, 10.1126/science.284.5417.1161
Sagiv, 2000, GATE-16, a membrane transport modulator, interacts with NSF and the Golgi v-SNARE GOS-28, EMBO J., 19, 1494, 10.1093/emboj/19.7.1494
Sanes, 1999, Development of the vertebrate neuromuscular junction, Annu. Rev. Neurosci., 22, 389, 10.1146/annurev.neuro.22.1.389
Sassoé-Pognetto, 2000, Gephyrin, a major postsynaptic protein of GABAergic synapses, Eur. J. Neurosci., 12, 2205, 10.1046/j.1460-9568.2000.00106.x
Sassoé-Pognetto, 1995, Colocalization of gephyrin and GABAA-receptor subunits in the rat retina, J. Comp. Neurol., 357, 1, 10.1002/cne.903570102
Sassoé-Pognetto, 2000, Colocalization of multiple GABA(A) receptor subtypes with gephyrin at postsynaptic sites, J. Comp. Neurol., 420, 481, 10.1002/(SICI)1096-9861(20000515)420:4<481::AID-CNE6>3.0.CO;2-5
Sassoé-Pognetto, 1997, Synaptogenesis in the rat retina: Subcellular localization of glycine receptors, GABAA receptors and the anchoring protein gephyrin, J. Comp. Neurol., 381, 158, 10.1002/(SICI)1096-9861(19970505)381:2<158::AID-CNE4>3.0.CO;2-2
Saxena, 1994, Assembly of GABAA receptor subunits: Role of the δ subunit, J. Neurosci., 14, 7077, 10.1523/JNEUROSCI.14-11-07077.1994
Scheiffele, 2000, Neuroligin expressed in nonneuronal cells triggers presynaptic development in contacting axons, Cell, 101, 657, 10.1016/S0092-8674(00)80877-6
Serpinskaya, 1999, Synapse formation by hippocampal neurons from agrindeficient mice, Dev. Biol., 205, 65, 10.1006/dbio.1998.9112
Sieghart, 1995, Structure and pharmacology of γ-aminobutyric acid A receptor subtypes, Pharmacol. Rev., 47, 181
Sieghart, 1999, Structure and subunit composition of GABA(A) receptors, Neurochem. Int., 34, 379, 10.1016/S0197-0186(99)00045-5
Sigel, 1990, The effect of subunit composition of rat brain GABAA receptors on channel function, Neuron, 5, 703, 10.1016/0896-6273(90)90224-4
Sigel, 1997, The benzodiazepine binding site of GABAA receptors, Trends Pharmacol. Sci., 18, 425, 10.1016/S0165-6147(97)90675-1
Sim, 1999, Targeting of PKA, PKC and protein phosphatases to cellular microdomains, Cell Calcium, 26, 209, 10.1054/ceca.1999.0072
Simbürger, 2001, Localization of two major GABAA receptor sub-units in the dentate gyrus of the rat and cell type specific upregulation following entorhinal cortex lesion, Neurosci., 102, 789, 10.1016/S0306-4522(00)00505-4
Smith, 1998, GABAA receptor α4 subunit suppression prevents withdrawal properties of an endogenous steroid, Nature, 392, 926, 10.1038/31948
Smith, 1998, Withdrawal from 3α-OH-5α-pregnan-20-one using a pseudopregnancy model alters the kinetics of hippocampal GABAA-gated current and increases the GABAA receptor α4 subunit in association with increased anxiety, J. Neurosci., 18, 5275, 10.1523/JNEUROSCI.18-14-05275.1998
Sohn, 1994, Profilin: at the crossroads of signal transduction and the actin cytoskeleton, Bioessays, 16, 465, 10.1002/bies.950160705
Song, 1999, Neuroligin 1 is a postsynaptic cell-adhesion molecule of excitatory synapses, Proc. Natl. Acad. Sci. USA, 96, 1100, 10.1073/pnas.96.3.1100
Swope, 1999, Regulation of ligandgated ion channels by protein phosphorylation, Adv. Second Messenger Phosphoprotein Res., 33, 49, 10.1016/S1040-7952(99)80005-6
Tanaka, 1997, Inhibition of GABAA synaptic responses by brain-derived neurotrophic factor (BDNF) in rat hippocampus, J. Neurosci., 17, 2959, 10.1523/JNEUROSCI.17-09-02959.1997
Tehrani, 1997, Sequestration of gamma-aminobutyric acidA receptors on clathrin-coated vesicles during chronic benzodiazepine administration in vivo, J. Pharmacol. Exp. Ther., 283, 384
Tehrani, 1997, Clathrin-coated vesicles from bovine brain contain uncoupled GABAA receptors, Brain Res., 776, 195, 10.1016/S0006-8993(97)01037-8
Tiihonen, 1997, Cerebral benzodiazepine receptor binding and distribution in generalized anxiety disorder: a fractal analysis, Mol. Psychiat., 2, 463, 10.1038/sj.mp.4000329
Todd, 1995, The relationship between glycine and gephyrin in synapses of the rat spinal cord, Eur. J. Neurosci., 7, 1, 10.1111/j.1460-9568.1995.tb01014.x
Todd, 1990, Light microscope study of the coexistence of GABA-like and glycine-like immunoreactivities in the spinal cord of the rat, J. Comp. Neurol., 296, 496, 10.1002/cne.902960312
Todd, 1996, Colocalization of GABA, glycine and their receptors at synapses in the rat spinal cord, J. Neurosci., 16, 974, 10.1523/JNEUROSCI.16-03-00974.1996
Tögel, 1994, γ-Aminobutyric acid receptors displaying association of γ3-subunits with β23 and different α-subunits exhibit unique pharmacological properties, J. Biol. Chem., 269, 12993, 10.1016/S0021-9258(18)99974-6
Tretter, 2001, Targeted disruption of the GABAA receptor δ subunit gene leads to an upregulation of γ2 subunit-containing receptors in cerebellar granule cells, J. Biol. Chem., 276, 10532, 10.1074/jbc.M011054200
Triller, 1987, Gamma-aminobutyric acid-containing terminals can be apposed to glycine receptors at central synapses, J. Cell Biol., 104, 947, 10.1083/jcb.104.4.947
Wan, 1997, Recruitment of functional GABAA receptors to postsynaptic domains by insulin, Nature, 388, 686, 10.1038/41792
Wang, 1999, GABAA-receptor-associated protein links GABAA receptors and the cytoskeleton, Nature, 397, 69, 10.1038/16264
Wang, 1991, Differential expression of two forms of GABAA receptor γ2-subunit in mice, Brain Res. Bull., 27, 731, 10.1016/0361-9230(91)90054-N
Whatley, 1996, The cytoskeleton and neurotransmitter receptors, Int. Rev. Neurobiol., 39, 113, 10.1016/S0074-7742(08)60665-0
Whiting, 1999, Molecular and functional diversity of the expanding GABA-A receptor gene family, Ann. N.Y. Acad. Sci., 868, 645, 10.1111/j.1749-6632.1999.tb11341.x
Whiting, 1997, Neuronally restricted RNA splicing regulates the expression of a novel GABAA receptor subunit conferring atypical functional properties, J. Neurosci., 17, 5027, 10.1523/JNEUROSCI.17-13-05027.1997
Wick, 2000, Behavioral changes produced by transgenic expression of γ2L and γ2S subunits of the GABAA receptor, Eur. J. Neurosci., 12, 2634, 10.1046/j.1460-9568.2000.00160.x
Wisden, 1992, The distribution of 13 GABAA receptor subunit mRNAs in the rat brain. I. Telencephalon, diencephalon, mesencephalon, J. Neurosci., 12, 1040, 10.1523/JNEUROSCI.12-03-01040.1992
Wisden, 1997, γ-Aminobutyric acid type A receptor subunit assembly and sorting: Gene targeting and cell biology approaches, Biochem. Soc. Transact., 25, 820, 10.1042/bst0250820
Witke, 1998, In mouse brain profilin I and profilin II associate with regulators of the endocytic pathway and actin assembly, EMBO J., 17, 967, 10.1093/emboj/17.4.967
Yakel, 1997, Calcineurin regulation of synaptic function: From ion channels to transmitter release and gene transcription, Trends Pharmacol. Sci., 18, 124, 10.1016/S0165-6147(97)01046-8
Ymer, 1990, Structural and functional characterization of the γ1 subunit of GABAA/benzodiazepine receptors, EMBO J., 9, 3261, 10.1002/j.1460-2075.1990.tb07525.x
Zhai, 1998, Phosphorylation of the GABAA receptor γ2L subunit in rat sensory neurons may not be necessary for ethanol sensitivity, Brain Res., 805, 116, 10.1016/S0006-8993(98)00689-1