Study on the mechanism of NLRP3 effect on the skeleton of de-ovalized mice

Lane, 2000, Osteoporosis, Clin. Orthop. Relat. Res., 139, 10.1097/00003086-200003000-00016 Yu, 2016, Osteoporosis: the result of an 'aged' bone microenvironment, Trends Mol. Med., 22, 641, 10.1016/j.molmed.2016.06.002 Crandall, 2020, Serial bone density measurement and incident fracture risk discrimination in postmenopausal women, JAMA Intern. Med., 180, 1232, 10.1001/jamainternmed.2020.2986 Liu, 2016, GDF11 decreases bone mass by stimulating osteoclastogenesis and inhibiting osteoblast differentiation, Nat. Commun., 7, 10.1038/ncomms12794 Randell, 2002, Does hormone-replacement therapy prevent fractures in early postmenopausal women?, J. Bone Miner. Res., 17, 528, 10.1359/jbmr.2002.17.3.528 De Villiers, 2015, The role of menopausal hormone therapy in the management of osteoporosis, Climacteric, 18, 19, 10.3109/13697137.2015.1099806 Harvey, 2010, Osteoporosis: impact on health and economics, Nat. Rev. Rheumatol., 6, 99, 10.1038/nrrheum.2009.260 Swanson, 2019, The NLRP3 inflammasome: molecular activation and regulation to therapeutics, Nat. Rev. Immunol., 19, 477, 10.1038/s41577-019-0165-0 Jo, 2016, Molecular mechanisms regulating NLRP3 inflammasome activation, Cell. Mol. Immunol., 13, 148, 10.1038/cmi.2015.95 Kelley, 2019, The NLRP3 inflammasome: an overview of mechanisms of activation and regulation, Int. J. Mol. Sci., 20, 10.3390/ijms20133328 Wang, 2020, The NLRP3 inflammasome: mechanism of action, role in disease and therapies, Mol. Aspect. Med., 76, 10.1016/j.mam.2020.100889 Detzen, 2021, NLRP3 is involved in long bone edification and the maturation of osteogenic cells, J. Cell. Physiol., 236, 4455, 10.1002/jcp.30162 Snouwaert, 2016, An NLRP3 mutation causes arthropathy and osteoporosis in humanized mice, Cell Rep., 17, 3077, 10.1016/j.celrep.2016.11.052 Galluzzi, 2018, Molecular mechanisms of cell death: recommendations of the nomenclature committee on cell death 2018, Cell Death Differ., 25, 486, 10.1038/s41418-017-0012-4 Sborgi, 2016, GSDMD membrane pore formation constitutes the mechanism of pyroptotic cell death, EMBO J., 35, 1766, 10.15252/embj.201694696 Ran, 2019, Enterococcus faecalis induces apoptosis and pyroptosis of human osteoblastic MG63 cells via the NLRP3 inflammasome, Int. Endod. J., 52, 44, 10.1111/iej.12965 Zhu, 2019, Inhibition of pyroptosis attenuates Staphylococcus aureus-induced bone injury in traumatic osteomyelitis, Ann. Transl. Med., 7, 170, 10.21037/atm.2019.03.40 Xu, 2018, Melatonin suppresses estrogen deficiency-induced osteoporosis and promotes osteoblastogenesis by inactivating the NLRP3 inflammasome, Calcif. Tissue Int., 103, 400, 10.1007/s00223-018-0428-y Lei, 2021, Interleukin-17 induces pyroptosis in osteoblasts through the NLRP3 inflammasome pathway in vitro, Int. Immunopharm., 96, 10.1016/j.intimp.2021.107781 Eghbali-Fatourechi, 2003, Role of RANK ligand in mediating increased bone resorption in early postmenopausal women, J. Clin. Invest., 111, 1221, 10.1172/JCI200317215 Bai, 2004, Oxidative stress inhibits osteoblastic differentiation of bone cells by ERK and NF-kappaB, Biochem. Biophys. Res. Commun., 314, 197, 10.1016/j.bbrc.2003.12.073 Novack, 2011, Role of NF-κB in the skeleton, Cell Res., 21, 169, 10.1038/cr.2010.159 Redlich, 2012, Inflammatory bone loss: pathogenesis and therapeutic intervention, Nat. Rev. Drug Discov., 11, 234, 10.1038/nrd3669 Agostini, 2004, NALP3 forms an IL-1beta-processing inflammasome with increased activity in Muckle-Wells autoinflammatory disorder, Immunity, 20, 319, 10.1016/S1074-7613(04)00046-9 Rovira-Llopis, 2018, Mitochondria, the NLRP3 inflammasome, and sirtuins in type 2 diabetes: new therapeutic targets, Antioxidants Redox Signal., 29, 749, 10.1089/ars.2017.7313 Mcallister, 2018, NLRP3 as a potentially novel biomarker for the management of osteoarthritis, Osteoarthritis Cartilage, 26, 612, 10.1016/j.joca.2018.02.901 Rheinheimer, 2017, Current role of the NLRP3 inflammasome on obesity and insulin resistance: a systematic review, Metabolism, 74, 1, 10.1016/j.metabol.2017.06.002 Szekanecz, 2019, The NLRP3 inflammasome - interleukin 1 pathway as a therapeutic target in gout, Arch. Biochem. Biophys., 670, 82, 10.1016/j.abb.2019.01.031 Cline-Smith, 2020, Ovariectomy activates chronic low-grade inflammation mediated by memory T cells, which promotes osteoporosis in mice, J. Bone Miner. Res., 35, 1174, 10.1002/jbmr.3966 Pietschmann, 2016, Immunology of osteoporosis: a mini-review, Gerontology, 62, 128, 10.1159/000431091 Mclean, 2009, Proinflammatory cytokines and osteoporosis, Curr. Osteoporos. Rep., 7, 134, 10.1007/s11914-009-0023-2 Dinarello, 2010, IL-1 family nomenclature, Nat. Immunol., 11, 973, 10.1038/ni1110-973 Percegoni, 2009, Profile of serum IL-1beta and IL-10 shortly after ovariectomy and estradiol replacement in rats, Horm. Metab. Res., 41, 50, 10.1055/s-0028-1087173 Khosla, 2013, Pathogenesis of age-related bone loss in humans, J Gerontol A Biol Sci Med Sci, 68, 1226, 10.1093/gerona/gls163 Tu, 2018, Osteoporosis: a review of treatment options, P t, 43, 92 Granéli, 2014, Novel markers of osteogenic and adipogenic differentiation of human bone marrow stromal cells identified using a quantitative proteomics approach, Stem Cell Res., 12, 153, 10.1016/j.scr.2013.09.009 Elbaz, 2010, Inhibition of fatty acid biosynthesis prevents adipocyte lipotoxicity on human osteoblasts in vitro, J. Cell Mol. Med., 14, 982, 10.1111/j.1582-4934.2009.00751.x Guo, 2022, FGF19 protects against obesity-induced bone loss by promoting osteogenic differentiation, Biomed. Pharmacother., 146, 10.1016/j.biopha.2021.112524 Liang, 2021, Glycolipid toxicity induces osteogenic dysfunction via the TLR4/S100B pathway, Int. Immunopharm., 97, 10.1016/j.intimp.2021.107792 Zhang, 2021, Necrosulfonamide reverses pyroptosis-induced inhibition of proliferation and differentiation of osteoblasts through the NLRP3/caspase-1/GSDMD pathway, Exp. Cell Res., 405, 10.1016/j.yexcr.2021.112648 Wang, 2017, NLRP3 inflammasome activation in mesenchymal stem cells inhibits osteogenic differentiation and enhances adipogenic differentiation, Biochem. Biophys. Res. Commun., 484, 871, 10.1016/j.bbrc.2017.02.007