Study of the association of total and differential white blood cell counts with geriatric conditions, cardio-vascular diseases, seric IL-6 levels and telomere length

Experimental Gerontology - Tập 61 - Trang 105-112 - 2015
Nathalie Compté1, Benjamin Bailly2, Sandra De Breucker3, Stanislas Goriely4, Thierry Pepersack5
1Service de gériatrie, Hôpital Soignies, Rue de la station 103, 7090 Braine-le-comte, Belgium
2Service d'hématologie, Hôpital Erasme, 808 route de Lennik, 1070 Bruxelles, Belgium
3Service de gériatrie, Hôpital Erasme, 808 route de Lennik, 1070 Bruxelles, Belgium
4Institute for Medical Immunology (IMI), Université Libre de Bruxelles, 8 rue Adrienne Bolland, B-6041 Charleroi, Belgium
5CHU Saint Pierre, Université Libre de Bruxelles, rue Haute 322, 1000 Bruxelles, Belgium

Tài liệu tham khảo

Andrews, 2010, Telomeres and immunological diseases of aging, Gerontology, 56, 390, 10.1159/000268620 Balasubramanyam, 2007, Telomere shortening & metabolic/vascular diseases, Indian J. Med. Res., 125, 441 Bauer, 2009, The role of stress factors during aging of the immune system, Ann. N. Y. Acad. Sci., 1153, 139, 10.1111/j.1749-6632.2008.03966.x Bautmans, 2005, A fatigue resistance test for elderly persons based on grip strength: reliability and comparison with healthy young subjects, Aging Clin. Exp. Res., 17, 217, 10.1007/BF03324600 Biagi, 2010, Through ageing, and beyond: gut microbiota and inflammatory status in seniors and centenarians, PLoS One, 5, e10667, 10.1371/journal.pone.0010667 Bruunsgaard, 2003, Predicting death from tumour necrosis factor-alpha and interleukin-6 in 80-year-old people, Clin. Exp. Immunol., 132, 24, 10.1046/j.1365-2249.2003.02137.x Carson, 2000, Immune function and vaccine responses in healthy advanced elderly patients, Arch. Intern. Med., 160, 2017, 10.1001/archinte.160.13.2017 Cawthon, 2002, Telomere measurement by quantitative PCR, Nucleic Acids Res., 30, e47, 10.1093/nar/30.10.e47 Chidrawar, 2009, Cytomegalovirus-seropositivity has a profound influence on the magnitude of major lymphoid subsets within healthy individuals, Clin. Exp. Immunol., 155, 423, 10.1111/j.1365-2249.2008.03785.x Collerton, 2012, Frailty and the role of inflammation, immunosenescence and cellular ageing in the very old: cross-sectional findings from the Newcastle 85+ study, Mech. Ageing Dev., 133, 456, 10.1016/j.mad.2012.05.005 Compte, 2013, Increased basal and alum-induced interleukin-6 levels in geriatric patients are associated with cardiovascular morbidity, PLoS One, 8, e81911, 10.1371/journal.pone.0081911 Cros, 2010, Human CD14dim monocytes patrol and sense nucleic acids and viruses via TLR7 and TLR8 receptors, Immunity, 33, 375, 10.1016/j.immuni.2010.08.012 Danesh, 2000, Low grade inflammation and coronary heart disease: prospective study and updated meta-analyses, BMJ, 321, 199, 10.1136/bmj.321.7255.199 Danesh, 2008, Long-term interleukin-6 levels and subsequent risk of coronary heart disease: two new prospective studies and a systematic review, PLoS Med., 5, e78, 10.1371/journal.pmed.0050078 Fernandez-Garrido, 2013, The value of neutrophil and lymphocyte count in frail older women, Exp. Gerontol., 54, 35, 10.1016/j.exger.2013.11.019 Ferrucci, 2002, Change in muscle strength explains accelerated decline of physical function in older women with high interleukin-6 serum levels, J. Am. Geriatr. Soc., 50, 1947, 10.1046/j.1532-5415.2002.50605.x Ferrucci, 2005, The origins of age-related proinflammatory state, Blood, 105, 2294, 10.1182/blood-2004-07-2599 Folstein, 1975, “Mini-mental state”: a practical method for grading the cognitive state of patients for the clinician, J. Psychiatr. Res., 12, 189, 10.1016/0022-3956(75)90026-6 Franceschi, 2000, Inflamm-aging: an evolutionary perspective on immunosenescence, Ann. N. Y. Acad. Sci., 908, 244, 10.1111/j.1749-6632.2000.tb06651.x Friedman, 1974, The leukocyte count as a predictor of myocardial infarction, N. Engl. J. Med., 290, 1275, 10.1056/NEJM197406062902302 Fulop, 2010, Potential role of immunosenescence in cancer development, Ann. N. Y. Acad. Sci., 1197, 158, 10.1111/j.1749-6632.2009.05370.x Gouin, 2008, Immune dysregulation and chronic stress among older adults: a review, Neuroimmunomodulation, 15, 251, 10.1159/000156468 Gutmajster, 2013, Telomere length in elderly Caucasians weakly correlates with blood cell counts, ScientificWorldJournal, 2013, 153608, 10.1155/2013/153608 Harris, 1999, Associations of elevated interleukin-6 and C-reactive protein levels with mortality in the elderly, Am. J. Med., 106, 506, 10.1016/S0002-9343(99)00066-2 Hodkinson, 2006, Whole blood analysis of phagocytosis, apoptosis, cytokine production, and leukocyte subsets in healthy older men and women: the ZENITH study, J. Gerontol. A Biol. Sci. Med. Sci., 61, 907, 10.1093/gerona/61.9.907 Hoene, 2008, The role of interleukin-6 in insulin resistance, body fat distribution and energy balance, Obes. Rev., 9, 20 Hristov, 2011, Differential role of monocyte subsets in atherosclerosis, Thromb. Haemost., 106, 757, 10.1160/TH11-07-0500 Hristov, 2010, Circulating monocyte subsets and cardiovascular risk factors in coronary artery disease, Thromb. Haemost., 104, 412, 10.1160/TH10-01-0069 Izaks, 2003, Lymphocyte count and mortality risk in older persons. The Leiden 85-plus study, J. Am. Geriatr. Soc., 51, 1461, 10.1046/j.1532-5415.2003.51467.x Jiang, 2007, Telomere shortening and ageing, Z. Gerontol. Geriatr., 40, 314, 10.1007/s00391-007-0480-0 Jiao, 2009, Reference ranges and age-related changes of peripheral blood lymphocyte subsets in Chinese healthy adults, Sci. China C Life Sci., 52, 643, 10.1007/s11427-009-0086-4 Ju, 2007, Telomere dysfunction induces environmental alterations limiting hematopoietic stem cell function and engraftment, Nat. Med., 13, 742, 10.1038/nm1578 Katz, 1963, Studies of illness in the aged. The index of ADL: a standardized measure of biological and psychos social function, JAMA, 185, 914, 10.1001/jama.1963.03060120024016 Leng, 2005, Total and differential white blood cell counts and their associations with circulating interleukin-6 levels in community-dwelling older women, J. Gerontol. A Biol. Sci. Med. Sci., 60, 195, 10.1093/gerona/60.2.195 Leng, 2007, Inflammation and frailty in older women, J. Am. Geriatr. Soc., 55, 864, 10.1111/j.1532-5415.2007.01186.x Leng, 2009, Associations of neutrophil and monocyte counts with frailty in community-dwelling disabled older women: results from the Women's Health and Aging Studies I, Exp. Gerontol., 44, 511, 10.1016/j.exger.2009.05.005 Leng, 2009, White blood cell counts, insulin-like growth factor-1 levels, and frailty in community-dwelling older women, J. Gerontol. A Biol. Sci. Med. Sci., 64, 499, 10.1093/gerona/gln047 Lin, 2010, Analyses and comparisons of telomerase activity and telomere length in human T and B cells: insights for epidemiology of telomere maintenance, J. Immunol. Methods, 352, 71, 10.1016/j.jim.2009.09.012 Linn, 1968, Cumulative Illness Rating Scale, J. Am. Geriatr. Soc., 16, 622, 10.1111/j.1532-5415.1968.tb02103.x Mccusker, 1998, Screening for geriatric problems in the emergency department: reliability and validity. Identification of Seniors at Risk (ISAR) Steering Committee, Acad. Emerg. Med., 5, 883, 10.1111/j.1553-2712.1998.tb02818.x Merino, 2011, Senescent CD14+ CD16+ monocytes exhibit proinflammatory and proatherosclerotic activity, J. Immunol., 186, 1809, 10.4049/jimmunol.1001866 Mollica, 2009, No association between telomere length and blood cell counts in elderly individuals, J. Gerontol. A Biol. Sci. Med. Sci., 64, 965, 10.1093/gerona/glp065 Nalapareddy, 2008, Determining the influence of telomere dysfunction and DNA damage on stem and progenitor cell aging: what markers can we use?, Exp. Gerontol., 43, 998, 10.1016/j.exger.2008.09.002 Parmelee, 1995, Validation of the Cumulative Illness Rating Scale in a geriatric residential population, J. Am. Geriatr. Soc., 43, 130, 10.1111/j.1532-5415.1995.tb06377.x Pinto, 2004, Neutrophil counts, monocyte counts and cardiovascular disease in the elderly, Exp. Gerontol., 39, 615, 10.1016/j.exger.2003.12.011 Poloni, 2013, Telomere length, c-myc and mad-1 expression could represent prognosis markers of myelodysplastic syndrome, Leuk. Res., 37, 1538, 10.1016/j.leukres.2013.07.022 Risques, 2010, Leukocyte telomere length is associated with disability in older U.S. Population, J. Am. Geriatr. Soc., 58, 1289, 10.1111/j.1532-5415.2010.02948.x Schmaltz, 2005, Chronic cytomegalovirus infection and inflammation are associated with prevalent frailty in community-dwelling older women, J. Am. Geriatr. Soc., 53, 747, 10.1111/j.1532-5415.2005.53250.x Seigel, 2012, Inadequacy of temperature and white blood cell count in predicting bacteremia in patients with suspected infection, J. Emerg. Med., 42, 254, 10.1016/j.jemermed.2010.05.038 Vellas, 1999, The Mini Nutritional Assessment (MNA) and its use in grading the nutritional state of elderly patients, Nutrition, 15, 116, 10.1016/S0899-9007(98)00171-3 Wagner, 2009, Aging and replicative senescence have related effects on human stem and progenitor cells, PLoS One, 4, e5846, 10.1371/journal.pone.0005846 Yang, 2011, Estrogen, hormonal replacement therapy and cardiovascular disease, Curr. Opin. Nephrol. Hypertens., 20, 133, 10.1097/MNH.0b013e3283431921 Yesavage, 1988, Geriatric Depression Scale, Psychopharmacol. Bull., 24, 709