Studies leading to the identification of ZD1839 (iressa™): an orally active, selective epidermal growth factor receptor tyrosine kinase inhibitor targeted to the treatment of cancer

Bioorganic & Medicinal Chemistry Letters - Tập 11 Số 14 - Trang 1911-1914 - 2001
Andrew Barker1, Keith H. Gibson2, Walter Grundy2, Andrew A. Godfrey2, Jeffrey J Barlow2, Mark P. Healy2, J.R. Woodburn2, Susan Ashton2, Brenda J Curry2, L. Scarlett2, Lianne Henthorn2, Laura M. Richards2
1AstraZeneca, Cancer and Infection Research, Mereside, Alderley Park, Macclesfield, SK10 4TG, Cheshire, UK.
2AstraZeneca, Cancer and Infection Research, Mereside, Alderley Park, Macclesfield, Cheshire SK10 4TG, UK

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