Structure of the human histamine H1 receptor complex with doxepin

Nature - Tập 475 Số 7354 - Trang 65-70 - 2011
Tatsuro Shimamura1, Mitsunori Shiroishi1, Simone Weyand1, Hirokazu Tsujimoto1, Graeme Winter2, Vsevolod Katritch3, Ruben Abagyan3, Vadim Cherezov4, Wei Liu4, Gye Won Han4, Takuya Kobayashi5, Raymond C. Stevens4, So Iwata5
1Human Receptor Crystallography Project, ERATO, Japan Science and Technology Agency, Yoshidakonoe-cho, Sakyo-ku, Kyoto 606-8501, Japan
2Diamond Light Source, Harwell Science and Innovation Campus, Chilton, Didcot, Oxfordshire OX11 0DE, UK
3Skaggs School of Pharmacy and Pharmaceutical Sciences and San Diego Supercomputer Center, University of California, San Diego, La Jolla, California 92093, USA ,
4Department of Molecular Biology,The Scripps Research Institute, 10550, North Torrey Pines Road, La Jolla, California 92037, USA
5Department of Cell Biology, Graduate School of Medicine, Kyoto University, Yoshidakonoe-cho, Sakyo-Ku, Kyoto 606-8501, Japan

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