Structure-function relationships of the LRRC8 subunits and subdomains of the volume-regulated anion channel (VRAC)
Tóm tắt
Từ khóa
Tài liệu tham khảo
Abascal, 2012, LRRC8 proteins share a common ancestor with pannexins and may form hexameric channels involved in cell-cell communication, Bioessays, 34, 551, 10.1002/bies.201100173
Amano, 2010, Rho-kinase/ROCK: a key regulator of the cytoskeleton and cell polarity, Cytoskeleton (Hoboken), 67, 545, 10.1002/cm.20472
Arreola, 1995, Volume-activated chloride channels in rat parotid acinar cells, J. Physiol., 484, 677, 10.1113/jphysiol.1995.sp020695
Cahalan, 1988, Role of potassium and chloride channels in volume regulation by T lymphocytes, Soc. Gen. Physiol. Ser., 43, 281
Cannon, 1998, Intracellular ionic strength regulates the volume sensitivity of a swelling-activated anion channel, Am. J. Physiol., 275, C416, 10.1152/ajpcell.1998.275.2.C416
Centeio, 2020, Ca2+ dependence of volume-regulated VRAC/LRRC8 and TMEM16A Cl− channels, Front. Cell Dev. Biol., 8, 596879, 10.3389/fcell.2020.596879
Choi, 2021, Oxidant-resistant LRRC8A/C anion channels support superoxide production by NADPH oxidase 1, J. Physiol., 599, 3013, 10.1113/JP281577
Decout, 2021, The cGAS-STING pathway as a therapeutic target in inflammatory diseases, Nat. Rev. Immunol., 21, 548, 10.1038/s41577-021-00524-z
Deneka, 2021, Allosteric modulation of LRRC8 channels by targeting their cytoplasmic domains, Nat. Commun., 12, 5435, 10.1038/s41467-021-25742-w
Deneka, 2018, Structure of a volume-regulated anion channel of the LRRC8 family, Nature, 558, 254, 10.1038/s41586-018-0134-y
Fisher, 2008, Volume-dependent osmolyte efflux from neural tissues: regulation by G-protein-coupled receptors, J. Neurochem., 106, 1998, 10.1111/j.1471-4159.2008.05510.x
Friard, 2019, LRRC8/VRAC channels exhibit a noncanonical permeability to glutathione, which modulates epithelial-to-mesenchymal transition (EMT), Cell Death Dis., 10, 925, 10.1038/s41419-019-2167-z
Ghosh, 2017, Leucine-rich repeat-containing 8B protein is associated with the endoplasmic reticulum Ca2+ leak in HEK293 cells, J. Cell Sci., 130, 3818, 10.1242/jcs.203646
Gradogna, 2017, Subunit-dependent oxidative stress sensitivity of LRRC8 volume-regulated anion channels, J. Physiol., 595, 6719, 10.1113/JP274795
Guizouarn, 1999, Swelling activation of transport pathways in erythrocytes: effects of Cl−, ionic strength and volume changes, Am. J. Physiol., 276, C210, 10.1152/ajpcell.1999.276.1.C210
Hazama, 1988, Ca2+ sensitivity of volume-regulatory K+ and Cl− channels in cultured human epithelial cells, J. Physiol., 402, 687, 10.1113/jphysiol.1988.sp017229
Hoffmann, 2009, Physiology of cell volume regulation in vertebrates, Physiol. Rev., 89, 193, 10.1152/physrev.00037.2007
Hyzinski-García, 2014, LRRC8A protein is indispensable for swelling-activated and ATP-induced release of excitatory amino acids in rat astrocytes, J. Physiol., 592, 4855, 10.1113/jphysiol.2014.278887
Jackson, 1994, The volume-sensitive organic osmolyte-anion channel VSOAC is regulated by nonhydrolytic ATP binding, Am. J. Physiol., 267, C1203, 10.1152/ajpcell.1994.267.5.C1203
Jalilehvand, 2009, Cadmium(II) complex formation with cysteine and penicillamine, Inorg. Chem., 48, 5758, 10.1021/ic802278r
Kasuya, 2018, Cryo-EM structures of the human volume-regulated anion channel LRRC8, Nat. Struct. Mol. Biol., 25, 797, 10.1038/s41594-018-0109-6
Kefauver, 2018, Structure of the human volume regulated anion channel, eLife, 7, e38461, 10.7554/eLife.38461
Kern, 2019, Cryo-EM structures of the DCPIB-inhibited volume-regulated anion channel LRRC8A in lipid nanodiscs, eLife, 8, e42636, 10.7554/eLife.42636
Lahey, 2020, LRRC8A:C/E heteromeric channels are ubiquitous transporters of cGAMP, Mol. Cell, 80, 578, 10.1016/j.molcel.2020.10.021
Lee, 2014, The protein synthesis inhibitor blasticidin s enters mammalian cells via leucine-rich repeat-containing protein 8D, J. Biol. Chem., 289, 17124, 10.1074/jbc.M114.571257
Levitan, 1995, Modulation of a volume-regulated chloride current by F-actin, J. Membr. Biol., 147, 283, 10.1007/BF00234526
Levitan, 2000, Membrane cholesterol content modulates activation of volume-regulated anion current in bovine endothelial cells, J. Gen. Physiol., 115, 405, 10.1085/jgp.115.4.405
Liu, 2019, Volume-regulated Cl− current: contributions of distinct Cl− channels and localized Ca2+ signals, Am. J. Physiol. Cell Physiol., 317, C466, 10.1152/ajpcell.00507.2018
López-Cayuqueo, 2022, Renal deletion of LRRC8/VRAC channels induces proximal tubulopathy, J. Am. Soc. Nephrol., 10.1681/ASN.2021111458
Lutter, 2017, Selective transport of neurotransmitters and modulators by distinct volume-regulated LRRC8 anion channels, J. Cell Sci., 130, 1122, 10.1242/jcs.196253
Nakamura, 2020, Cryo-EM structure of the volume-regulated anion channel LRRC8D isoform identifies features important for substrate permeation, Commun. Biol., 3, 240, 10.1038/s42003-020-0951-z
Ng, 2011, Leucine-rich repeat (LRR) proteins: integrators of pattern recognition and signaling in immunity, Autophagy, 7, 1082, 10.4161/auto.7.9.16464
Nilius, 1997, Properties of volume-regulated anion channels in mammalian cells, Prog. Biophys. Mol. Biol., 68, 69, 10.1016/s0079-6107(97)00021-7
Nilius, , Activation of volume-regulated chloride currents by reduction of intracellular ionic strength in bovine endothelial cells, J. Physiol., 506, 353, 10.1111/j.1469-7793.1998.353bw.x
Nilius, , Modulation of volume-regulated anion channels by extra- and intracellular pH, Pflugers Arch., 436, 742, 10.1007/s004240050697
Nilius, 1999, Role of Rho and Rho kinase in the activation of volume-regulated anion channels in bovine endothelial cells, J. Physiol., 516, 67, 10.1111/j.1469-7793.1999.067aa.x
Okada, 2017, Specific and essential but not sufficient roles of LRRC8A in the activity of volume-sensitive outwardly rectifying anion channel (VSOR), Channels (Austin), 11, 109, 10.1080/19336950.2016.1247133
Pasantes-Morales, 2016, Channels and volume changes in the life and death of the cell, Mol. Pharmacol., 90, 358, 10.1124/mol.116.104158
Pervaiz, 2019, Absolute protein amounts and relative abundance of volume-regulated anion channel (VRAC) LRRC8 subunits in cells and tissues revealed by quantitative immunoblotting, Int. J. Mol. Sci., 20, 5879, 10.3390/ijms20235879
Planells-Cases, 2015, Subunit composition of VRAC channels determines substrate specificity and cellular resistance to Pt-based anti-cancer drugs, EMBO J., 34, 2993, 10.15252/embj.201592409
Platt, 2017, Leucine-rich repeat containing 8A (LRRC8A)-dependent volume-regulated anion channel activity is dispensable for T-cell development and function, J. Allergy Clin. Immunol., 140, 1651, 10.1016/j.jaci.2016.12.974
Qiu, 2014, SWELL1, a plasma membrane protein, is an essential component of volume-regulated anion channel, Cell, 157, 447, 10.1016/j.cell.2014.03.024
Rudkouskaya, 2008, Two conventional protein kinase C isoforms, alpha and beta I, are involved in the ATP-induced activation of volume-regulated anion channel and glutamate release in cultured astrocytes, J. Neurochem., 105, 2260, 10.1111/j.1471-4159.2008.05312.x
Sabirov, 2000, Extra- and intracellular proton-binding sites of volume-regulated anion channels, J. Membr. Biol., 177, 13, 10.1007/s002320001090
Sawada, 2003, A congenital mutation of the novel gene LRRC8 causes agammaglobulinemia in humans, J. Clin. Invest., 112, 1707, 10.1172/JCI18937
Schwiebert, 1994, Actin-based cytoskeleton regulates a chloride channel and cell volume in a renal cortical collecting duct cell line, J. Biol. Chem., 269, 7081, 10.1016/S0021-9258(17)37249-6
Syeda, 2016, LRRC8 proteins form volume-regulated anion channels that sense ionic strength, Cell, 164, 499, 10.1016/j.cell.2015.12.031
Ullrich, 2016, Inactivation and anion selectivity of volume-regulated anion channels (VRACs) depend on c-terminal residues of the first extracellular loop, J. Biol. Chem., 291, 17040, 10.1074/jbc.M116.739342
Voets, 1999, Reduced intracellular ionic strength as the initial trigger for activation of endothelial volume-regulated anion channels, Proc. Natl. Acad. Sci. U S A, 96, 5298, 10.1073/pnas.96.9.5298
Voss, 2014, Identification of LRRC8 heteromers as an essential component of the volume-regulated anion channel VRAC, Science, 344, 634, 10.1126/science.1252826
Wang, 2017, The volume-regulated anion channel (LRRC8) in nodose neurons is sensitive to acidic pH, JCI Insight, 2, e90632, 10.1172/jci.insight.90632
Yamada, 2018, Intracellular and extracellular loops of LRRC8 are essential for volume-regulated anion channel function, J. Gen. Physiol., 150, 1003, 10.1085/jgp.201812016
Yang, 2019, Glutamate-releasing SWELL1 channel in astrocytes modulates synaptic transmission and promotes brain damage in stroke, Neuron, 102, 813, 10.1016/j.neuron.2019.03.029
Zhang, 2008, DCPIB, a specific inhibitor of volume regulated anion channels (VRACs), reduces infarct size in MCAo and the release of glutamate in the ischemic cortical penumbra, Exp. Neurol., 210, 514, 10.1016/j.expneurol.2007.11.027