Structure and functionality in flavivirus NS-proteins: Perspectives for drug design

Antiviral Research - Tập 87 Số 2 - Trang 125-148 - 2010
Michela Bollati1, Karin Álvarez2, R. Assenberg3, Cécile Baronti4, Bruno Canard2, Shelley Cook5, Bruno Coutard2, Étienne Decroly2, Xavier de Lamballerie4, Ernest A. Gould6, Gilda Grard4, J.M. Grimes3, Rolf Hilgenfeld7, Anna Jansson8, Hélène Malet2, Erika J. Mancini3, Eloise Mastrangelo1, Andrea Mattevi9, Mario Milani1, Grégory Moureau4, Johan Neyts10, Raymond J. Owens3, Jingshan Ren3, Barbara Selisko2, Silvia Speroni9, H. Steuber7, David I. Stuart3, Torsten Unge8, Martino Bolognesi1
1Department of Biomolecular Sciences and Biotechnology, University of Milano, Via Celoria 26, 20133 Milano, Italy
2Laboratoire Architecture et Fonction des Macromolécules Biologiques, CNRS UMR-6098, Universités Aix-Marseille I et II, ESIL Case 925, 163 Avenue de Luminy, 13288 Marseille, France.
3Oxford Protein Production Facility, Wellcome Trust Centre for Human Genetics, Roosevelt Drive, Headington, Oxford OX3 7BN, UK
4Unité des Virus Emergents, Faculté de Médecine, 27 Bd Jean Moulin, 13005 Marseille, France
5The Natural History Museum, Cromwell Road, London, United Kingdom
6Centre for Ecology and Hydrology, Mansfield Road, Oxford, OX1 3SR, United Kingdom
7Institute of Biochemistry, Center for Structural and Cell Biology in Medicine, University of Lübeck, Ratzeburger Allee 160, 23538 Lübeck, Germany
8Department of Cell & Molecular Biology, Uppsala University, Biomedical Center, Box 596, SE-751 24, Uppsala, Sweden.
9Department of Genetics and Microbiology, University of Pavia, Via Ferrata 7, 27100 Pavia, Italy
10Rega Institute for Medical Research, KULeuven - University of Leuven, Minderbroedersstraat 10, 3000 Leuven, Belgium

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