Structure-activity relationships of agonists for the orphan G protein-coupled receptor GPR27
Tài liệu tham khảo
Alexander, 2018, Pharmacogenomics of GPCR drug targets, Cell, 172, 41, 10.1016/j.cell.2017.11.033
Chung, 2008, Orphan GPCR research, Br. J. Pharmacol., 153, S339, 10.1038/sj.bjp.0707606
Laschet, 2018, The G protein-coupled receptors deorphanization landscape, Biochem. Pharmacol., 153, 62, 10.1016/j.bcp.2018.02.016
De, 2009, G Protein-coupled receptors as targets for drug design, Biotecnol. Apl., 26, 24
Matsumoto, 2000, An evolutionarily conserved G-protein coupled receptor family, SREB, Expressed in the Central Nervous System, Biochem. Biophys. Res. Commun., 272, 576, 10.1006/bbrc.2000.2829
Fredriksson, 2003, The G-proteincoupled receptors in the human genome form five main families: phylogenetic analysis, paralogon groups, and fingerprints, Mol. Pharmacol., 63, 1256, 10.1124/mol.63.6.1256
Regard, 2008, Anatomical profiling of G protein-coupled receptor expression, Cell, 135, 561, 10.1016/j.cell.2008.08.040
Hellebrand, 2001, GPR85, a novel member of the G-protein coupled receptor family, prominently expressed in the developing mouse cerebral cortex, Brain Res. Gene Expr. Patterns, 1, 13, 10.1016/S1567-133X(01)00002-3
Ku, 2012, An siRNA screen in pancreatic beta cells reveals a role for GPR27 in insulin production, PLoS Genet., 8, 10.1371/journal.pgen.1002449
Chopra, 2020, Deletion of GPR27 in vivo reduces insulin mRNA but does not result in diabetes, Sci. Rep., 10, 5629, 10.1038/s41598-020-62358-4
Nath, 2020, Genetic deletion of GPR27 alters acylcarnitine metabolism, insulin sensitivity, and glucose homeostasis in zebrafish, Faseb. J., 34, 1546, 10.1096/fj.201901466R
Dupuis, 2017, Activation of the orphan G protein-coupled receptor GPR27 by surrogate ligands promotes β -arrestin 2 recruitment, Mol. Pharmacol., 91, 595, 10.1124/mol.116.107714
Kroeze, 2015, PRESTO-Tango as an open-source resource for interrogation of the druggable human GPCRome, Nat. Struct. Mol. Biol., 22, 362, 10.1038/nsmb.3014
Yanai, 2016, Identification and molecular docking studies for novel inverse agonists of SREB, super conserved receptor expressed in brain, Gene Cell., 21, 717, 10.1111/gtc.12378
Ge, 2020, Discovery of secondary sulphonamides as Ido1 inhibitors with potent antitumour effects in vivo, J. Enzym. Inhib. Med. Chem., 35, 1240, 10.1080/14756366.2020.1765165
Xu, 2020, Synthesis and evaluation of 3-(4-(phenoxymethyl)phenyl)propanoic acid and N-phenylbenzenesulfonamide derivatives as FFA4 agonists, Bioorg. Med. Chem. Lett, 30, 127650, 10.1016/j.bmcl.2020.127650
Silveira, 2021, Comparative study between the anti-P. falciparum activity of triazolopyrimidine, pyrazolopyrimidine and quinoline derivatives and the identification of new PfDHODH inhibitors, Eur. J. Med. Chem., 209, 112941, 10.1016/j.ejmech.2020.112941
Batra, 2018, Synthesis and antimalarial evaluation of [1,2,3]-triazole-tethered sulfonamide-berberine hybrids, ChemistrySelect, 3, 9790, 10.1002/slct.201801905
Franco, 2015, Structure-based discovery of small molecule hepsin and HGFA protease inhibitors: evaluation of potency and selectivity derived from distinct binding pockets Bioorg, Med. Chem., 23, 2328
Boechat, 2020, Comparative study between the anti-P. falciparum activity of triazolopyrimidine, pyrazolopyrimidine and quinoline derivatives and the identification of new PfDHODH inhibitors, Bioorg. Med. Chem., 28, 115832, 10.1016/j.bmc.2020.115832
Uysal, 2021, Design, synthesis and biological evaluation of novel naphthoquinone-4-aminobenzensulfonamide/carboxamide derivatives as proteasome inhibitors, Eur. J. Med. Chem., 209, 112890, 10.1016/j.ejmech.2020.112890
Turcotte, 2012, Synthesis, biological evaluation, and structure-activity relationships of novel substituted N-phenylureidobenzenesulfonate derivatives blocking cell cycle progression in S-phase and inducing DNA double-strand breaks, J. Med. Chem., 55, 6194, 10.1021/jm3006492
Zhang, 2013, Discovery of N-(4-sulfamoylphenyl)thioureas as Trypanosoma brucei leucyl-tRNA synthetase inhibitors, Org. Biomol. Chem., 11, 5310, 10.1039/c3ob40236c
Wang, 2017, Structure-based virtual screening and optimization of modulators targeting Hsp90-Cdc37 interaction, Eur. J. Med. Chem., 136, 63, 10.1016/j.ejmech.2017.04.074
Fakhouri, 2017, Design, synthesis and biological evaluation of GPR55 agonists, Bioorg. Med. Chem., 25, 4355, 10.1016/j.bmc.2017.06.016
Qandil, 2008, Synthesis and anticandidal activity of azole-containing sulfonamides, Arch. Pharm (Weinheim), 341, 99, 10.1002/ardp.200700125
Sastry, 2011, Rapid shape-based ligand alignment and virtual screening method based on atom/feature-pair similarities and volume overlap scoring, J. Chem. Inf. Model., 51, 2455, 10.1021/ci2002704
Friesner, 2006, Extra Precision Glide: Docking and scoring incorporating a model of hydrophobic enclosure for protein−ligand complexes, J. Med. Chem., 49, 6177, 10.1021/jm051256o
Sherman, 2006, Novel procedure for modeling ligand/receptor induced fit effects, J. Med. Chem., 49, 534, 10.1021/jm050540c
Jacobson, 2004, A hierarchical approach to all-atom protein loop prediction, Proteins, 55, 351, 10.1002/prot.10613
Huang, 2006, Physics-based scoring of protein-ligand complexes: enrichment of known inhibitors in large-scale virtual screening, J. Chem. Inf. Model., 46, 243, 10.1021/ci0502855
Abel, 2008, Role of the active-site solvent in the thermodynamics of factor Xa ligand binding, J. Am. Chem. Soc., 130, 2817, 10.1021/ja0771033