Structure–Activity Relationship in Monosaccharide-Based Toll-Like Receptor 4 (TLR4) Antagonists

Journal of Medicinal Chemistry - Tập 61 Số 7 - Trang 2895-2909 - 2018
Fabio A. Facchini1, Lenny Zaffaroni1, Alberto Minotti1, Silvia Rapisarda1, Valentina Calabrese1, Matilde Forcella1, Paola Fusi1, Cristina Airoldi1, Carlotta Ciaramelli1, Jean‐Marc Billod2, Andra B. Schromm3, Harald Braun4, Charys Palmer5, Rudi Beyaert4, Fabio Lapenta6, Roman Jerala6, Grisha Pirianov5, Sonsoles Martín‐Santamaría2, Francesco Peri1
1Department of Biotechnology and Biosciences, University of Milano-Bicocca, Piazza della Scienza 2, 20126 Milano, Italy
2Department of Structural & Chemical Biology, Centro de Investigaciones Biologicas, CIB-CSIC, C/Ramiro de Maeztu, 9, 28040 Madrid, Spain
3Division of Immunobiophysics, Research Center Borstel, Parkallee 1-40, 23845 Borstel, Germany
4VIB-UGent Center for Inflammation Research, UGent Department for Biomedical Molecular Biology, Unit of Molecular Signal Transduction in Inflammation, Technologiepark 927, 9052 Ghent, Belgium
5Anglia Ruskin Cambridge University, Cambridge CB1 1PT, U.K.
6Department of Synthetic Biology and Immunology, Kemijski Institute, National Institute of Chemistry, Hajdrihova 19, SI-1000 Ljubljana, Slovenia

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Journal of Medicinal Chemistry

Tập 61 Số 7

2895-2909

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