Structural changes of the central nervous system in swayback (Enzootic Ataxia) of lambs
Tóm tắt
The ultrastructure of the nerve cell change in swayback is presented. Notable features are an increase in cell size, progressive loss of Nissl substance, alteration in form and distribution of the Golgi apparatus and a striking increase in neurofibrils within the perikaryon. Similarities and differences in the fine structural changes of other pathological states are discussed.
Tài liệu tham khảo
Barlow, R. M., andP. A. Cancilla: Structural changes of the central nervous system in Swayback disease of lambs. I. Light microscopy using phosphatases as organelle markers. Acta neuropath. (Berl.)6, 175–180 (1966).
—,D. Purves, E. J. Butler, andI. Jean Macintyre: Swayback in south-east Scotland. II. Clinical, Pathological and biochemical aspects. J. comp. Path.70, 411–428 (1960).
Bodian, D.: An electron microscopic study of the monkey spinal cord. I. Fine structure of normal motor column. II. Effects of retrograde chromatolysis. III. Cytological effects of mild and virulent polio-virus infection. Bull. Johns Hopk. Hosp.114, 13–119 (1964).
Chou, S. M., andH. A. Hartmann: Axonal lesions and waltzing syndrome after I. D. P. N. Administration in rats. With a concept-axostasis. Acta neuropath. (Berl.)3, 428–450 (1963/64).
Evans, D. H., andE. G. Gray: Changes in the fine structure of ganglion cells during chromatolysis. In: Cytology of nervous tissue, p. 71. Proc. Anat. Soc. Gr. Brit. and Ireland. London: Taylor and Francis 1961.
Holt, S. J., andR. M. Hicks: The localization of acid phosphatase in rat liver cells as revealed by combined cytochemical staining and electron microscopy. J. biophys. biochem. Cytol.11, 47–66 (1961).
Hudson, G., A. Lazarow, andJ. F. Hartmann: A quantitative electron microscopic study of mitochondria in motor neurons following axonal section. Exp. Cell Res.24, 440–456 (1961).
Kidd, M.: Alzheimer's disease. An electron microscopical study. Brain87, 307–320 (1964).
Luft, J. H.: Improvements in epoxy resin embedding methods. J. biophys. biochem. Cytol.9, 409–414 (1961).
Millonig, G.: Advantages of a phosphate buffer for OsO4 solutions in fixation. J. appl. Physiol.32, 1637 (1961).
Novikoff, A. B., andE. Essner: Pathological changes in cytoplasmic organelles. Fed. Proc.21, 1130–1142 (1962).
Sabatini, D. D., K. Bensch, andR. R. Barnett: Cytochemistry and electron microscopy. The preservation of cellular ultrastructure and enzymatic activity by aldehyde fixation. J. Cell Biol.17, 19–58 (1963).
Terry, R. D.: The fine structure of neurofibrillary tangles in Alzheimer's disease. J. Neuropath. exp. Neurol.22, 629–642 (1963).