Stress Testing for Coronary Artery Disease in the Elderly

1990, Guidelines for the elderly management of patients with acute myocardial infarction: A report of the ACC/AHA task force on assessment of diagnostic and therapeutic cardiovascular procedures, Circulation, 82, 664, 10.1161/01.CIR.82.2.664 Armstrong, 1987, Exercise echocardiography: Effect of prior infarction and extent of coronary artery disease on accuracy, J Am Coll Cardiol, 10, 531, 10.1016/S0735-1097(87)80195-X Applegate, 1987, Usefulness of two-dimensional echocardiography during low-level exercise testing early after uncomplicated acute myocardial infarction, Am J Cardiol, 60, 10, 10.1016/0002-9149(87)90974-X Bateman, 1992, Pharmacologic (stress) perfusion scintigraphy: Methods, advantages, and applications, American Journal of Cardiac Imaging, 6, 3 Beller, 1987, Sensitivity, specificity, and prognostic significance of noninvasive testing for occult or known coronary disease, Prog Cardiovasc Dis, 29, 241, 10.1016/S0033-0620(87)80002-6 Bruce, 1980, Value of maximal exercise tests in risk assessment of primary coronary heart disease events in healthy men: Five years’ experience of the Seattle Heart Watch Study, Am J Cardiol, 46, 371, 10.1016/0002-9149(80)90003-X Camerieri, 1993, Prognostic value of dipyridamole echocardiography early after myocardial infarction in elderly patients, J Am Coll Cardiol, 22, 1809, 10.1016/0735-1097(93)90762-P Chae, 1993, Identification of extensive coronary artery disease in women by exercise single-photon emission computed tomographic (SPECT) thallium imaging, J Am Coll Cardiol, 21, 1305, 10.1016/0735-1097(93)90301-G Chaitman, 1981, Angiographic prevalence of high-risk coronary artery disease in patient subsets (CASS), Circulation, 64, 360, 10.1161/01.CIR.64.2.360 Christian, 1994, Exercise tomographic thallium-201 imaging in patients with severe coronary artery disease and normal electrocardiogram, Ann Intern Med, 121, 825, 10.7326/0003-4819-121-11-199412010-00001 Christian, 1992, Noninvasive identification of severe coronary artery disease using exercise tomographic thallium-201 imaging, Am J Cardiol, 70, 14, 10.1016/0002-9149(92)91382-E Ciaroni, 1993, Early exercise testing after acute myocardial infarction in the elderly: Clinical evaluation and prognostic significance, Am Heart J, 126, 304, 10.1016/0002-8703(93)91044-F Corbett, 1981, The prognostic value of submaximal exercise testing with radionuclide ventriculography before hospital discharge in patients with recent myocardial infarction, Circulation, 64, 535, 10.1161/01.CIR.64.3.535 de Cock, 1992, Prognostic value of thallium-201 exercise scintigraphy in low-risk patients after Q-wave myocardial infarction: Comparison with exercise testing and catheterization, Cardiology, 81, 342, 10.1159/000175828 Cohen, 1993, Comparison of dobutamine and exercise echocardiography for detecting coronary artery disease, Am J Cardiol, 72, 1226, 10.1016/0002-9149(93)90288-N Cohn, 1992, Prognosis in exercise-induced silent myocardial ischemia and implications for screening asymptomatic individuals, Prog Cardiovasc Dis, 34, 399, 10.1016/0033-0620(92)90007-M Cohn, 1987, Quantitative exercise testing for the cardiac patient: The value of monitoring gas exchange: Introduction, Circulation, 76, VI Crouse, 1991, Exercise echocardiography as a screening test for coronary artery disease and correlation with coronary angiography, Am J Cardiol, 67, 1213, 10.1016/0002-9149(91)90929-F Davidson, 1980, Prognostic value of a single exercise test 3 weeks after uncomplicated myocardial infarction, Circulation, 61, 236, 10.1161/01.CIR.61.2.236 Deckers, 1984, A Ineligibility for predischarge exercise testing after myocardial infarction in the elderly: Implication for prognosis, Eur Heart J, 5, 97, 10.1093/eurheartj/5.suppl_E.97 DeFeyter, 1982, Prognostic value of exercise testing, coronary angiography and left ventriculography 6-8 weeks after myocardial infarction, Circulation, 66, 527, 10.1161/01.CIR.66.3.527 Dehn, 1972, Longitudinal variations in maximal oxygen intake with age and activity, J Appl Physiol, 33, 805, 10.1152/jappl.1972.33.6.805 Diamond, 1979, Analysis of probability as an aid in the clinical diagnosis of coronary-artery disease, N Engl J Med, 300, 1350, 10.1056/NEJM197906143002402 Ehsani, 1991, Exercise training improves left ventricular systolic function in older men, Circulation, 83, 96, 10.1161/01.CIR.83.1.96 Elveback, 1984, Continued high incidence of coronary artery disease at autopsy in Olmsted County, Minnesota, 1950 to 1979, Circulation, 70, 345, 10.1161/01.CIR.70.3.345 Fioretti, 1984, A Predischarge stress test after myocardial infarction in old age: Results and prognostic value, Eur Heart J, 5, 101, 10.1093/eurheartj/5.suppl_E.101 Fleg, 1990, Gender differences in exercise hemodynamics of older subjects: Effects of conditioning status (abstract), Circulation, 82, 239 Fleg, 1994, Effects of acute B-adrenergic blockade on age-associated changes in cardiovascular performance during dynamic exercise, Circulation, 90, 2333, 10.1161/01.CIR.90.5.2333 Fleg, 1989, Exercise testing for elderly patients, Cardiology, 6, 105 Fleg, 1990, Independent effects of age and gender on specificity of ejection fraction response to upright cycle exercise (abstract), Circulation, 82, 137 Fleg, 1990, Prevalence and prognostic signifiance of exercise-induced silent myocardial ischemia detected by thallium scintigraphy and electrocardiography in asymptomatic volunteers, Circulation, 81, 428, 10.1161/01.CIR.81.2.428 Fleg, 1993, Additive effects of age and silent myocardial ischemia on the left ventricular response to upright exercise, J Appl Physiol, 75, 499, 10.1152/jappl.1993.75.2.499 Fletcher, 1995, Exercise standards: A statement for healthcare professionals from the American Heart Association, Circulation, 91, 580, 10.1161/01.CIR.91.2.580 Froelicher, 1987, Application of meta-analysis using an electronic spread sheet to exercise testing in patients after myocardial infarction, Am J Med, 83, 1045, 10.1016/0002-9343(87)90940-5 Gaul, 1984, Stress testing in persons above the age of 65 years: Applicability and diagnostic value of a standardized maximal symptom-limited testing protocol, Eur Heart J, 5, 51, 10.1093/eurheartj/5.suppl_E.51 Gersh, 1985, Comparison of coronary artery bypass surgery and medical therapy in patients 65 years of age or older, N Engl J Med, 313, 217, 10.1056/NEJM198507253130403 Giagnoni, 1983, Prognostic value of exercise EKG testing in asymptomatic normotensive subjects, N Engl J Med, 309, 1085, 10.1056/NEJM198311033091803 Glover, 1984, Diagnostic exercise testing in 104 patients over 65 years of age., Eur Heart J, 5, 59, 10.1093/eurheartj/5.suppl_E.59 Gianrossi, 1989, Exercise-induced ST depression in the diagnosis of coronary artery disease: A meta-analysis, Circulation, 80, 87, 10.1161/01.CIR.80.1.87 Gibson, 1981, Predicting the extent and location of coronary artery disease during the early postinfarction period by quantitative thallium-201 scintigraphy, Am J Cardiol, 47, 1010, 10.1016/0002-9149(81)90206-X Gibson, 1983, Prediction of cardiac events after uncomplicated myocardial infarction: A prospective study comparing predischarge exercise thallium-201 scintigraphy and coronary angiography, Circulation, 68, 321, 10.1161/01.CIR.68.2.321 Haber, 1993, Exercise thallium-201 scintigraphy after thrombolytic therapy with or without angioplasty for acute myocardial infarction, Am J Cardiol, 71, 1257, 10.1016/0002-9149(93)90536-L Heath, 1981, A physiological comparison of young and older endurance athletes, J Appl Physiol, 51, 634, 10.1152/jappl.1981.51.3.634 Hendel, 1992, Prediction of late cardiac events by dipyridamole thallium imaging in patients undergoing elective vascular surgery, Am J Cardiol, 70, 1243, 10.1016/0002-9149(92)90756-O Hlatky, 1984, Factors affecting sensitivity and specificity of exercise electrocardiography: Multivariate analysis, Am J Med, 77, 64, 10.1016/0002-9343(84)90437-6 Hung, 1984, Comparative value of maximal treadmill testing, exercise thallium perfusion scintigraphy and exercise radionuclide ventriculography for distinguishing high-and low-risk patients soon after acute myocardial infarction, Am J Cardiol, 53, 1221, 10.1016/0002-9149(84)90068-7 Iskandrian, 1993, Identification of high-risk patients with left main and three-vessel coronary artery disease using stepwise discriminant analysis of clinical, exercise, and tomographic thallium data, Am Heart J, 125, 221, 10.1016/0002-8703(93)90078-N Iskandrian, 1993, Independent and incremental prognostic value of exercise single-photon emission computed tomographic (SPECT) thallium imaging in coronary artery disease, J Am Coll Cardiol, 22, 665, 10.1016/0735-1097(93)90174-Y Iskandrian, 1988, Use of exercise thallium-201 imaging for risk stratification of elderly patients with coronary artery disease, Am J Cardiol, 61, 269, 10.1016/0002-9149(88)90929-0 Josephson, 1990, Can serial exercise testing improve the prediction of coronary events in asymptomatic individuals?, Circulation, 81, 20, 10.1161/01.CIR.81.1.20 Kaul, 1988, Prognostic utility of the exercise thallium-201 test in ambulatory patients with chest pain: Comparison with cardiac catheterization, Circulation, 77, 745, 10.1161/01.CIR.77.4.745 Knatterud, 1994, Effects of treatment strategies to suppress ischemia in patients with coronary artery disease: 12-week results of the Asymptomatic Cardiac Ischemia Pilot (ACIP) study, J Am Coll Cardiol, 24, 11, 10.1016/0735-1097(94)90535-5 Krone, 1992, The role of risk stratification in the early management of a myocardial infarction, Ann Intern Med, 116, 223, 10.7326/0003-4819-116-3-223 Lakatta, 1993, Cardiovascular regulatory mechanisms in advanced age, Physiol Rev, 73, 413, 10.1152/physrev.1993.73.2.413 Lam, 1988, Safety and diagnostic accuracy of dipyridamole-thallium imaging in the elderly, J Am Coll Cardiol, 11, 585, 10.1016/0735-1097(88)91535-5 Mark, 1991, Prognostic value of a treadmill exercise score in outpatients with suspected coronary artery disease, N Engl J Med, 325, 849, 10.1056/NEJM199109193251204 Mark, 1987, Localizing coronary artery obstructions with the exercise treadmill test, Ann Intern Med, 106, 53, 10.7326/0003-4819-106-1-53 Miller, 1994, Dipyridamole and adenosine vasodilator stress for myocardial imaging Vive la Difference!, J Am Coll Cardiol, 23, 390, 10.1016/0735-1097(94)90425-1 Miller, 1994, Severe exercise-induced ischemia does not identify high risk patients with normal left ventricular function and one or two-vessel coronary artery disease, J Am Coll Cardiol, 23, 219, 10.1016/0735-1097(94)90523-1 Morrow, 1993, Prediction of cardiovascular death in men undergoing noninvasive evaluation for coronary artery disease, Ann Intern Med, 118, 689, 10.7326/0003-4819-118-9-199305010-00005 Morris, 1993, Nomogram based on metabolic equivalents and age for assessing aerobic exercise capacity in men, J Am Coll Cardiol, 22, 175, 10.1016/0735-1097(93)90832-L Morris, 1978, Incidence and significance of decreases in systolic blood pressure during graded treadmill exercise testing, Am J Cardiol, 41, 221, 10.1016/0002-9149(78)90160-1 Moss, 1990, Prognosis and management after a first myocardial infarction, N Engl J Med, 322, 743, 10.1056/NEJM199003153221107 1985, Exercise electrocardiogram and coronary heart disease mortality in the Multiple Risk Factor Intervention Trial, Am J Cardiol, 55, 16, 10.1016/0002-9149(85)90291-7 Myers, 1993, Are routine noninvasive tests useful in prediction of outcome after myocardial infarction in elderly people?, Lancet, 342, 1069, 10.1016/0140-6736(93)92060-7 National Center for Health Statistics: Health, United States, 1984. DHHS Publication No. (PHS)85-1232, Hyattsville, Maryland, 1984 Nygaard, 1984, Prevalence of high-risk thallium-201 scintigraphic findings in left main coronary artery stenosis: Comparison with patients with multiple- and single-vessel coronary artery disease, Am J Cardiol, 53, 462, 10.1016/0002-9149(84)90013-4 Ogawa, 1992, Effects of aging, sex, and physical training on cardiovascular responses to exercise, Circulation, 86, 494, 10.1161/01.CIR.86.2.494 Pepine, 1994, Effects of treatment on outcome in mildly symptomatic patients with ischemia during dialy life: The Atenolol Silent Ischemia Study (ASIST), Circulation, 90, 762, 10.1161/01.CIR.90.2.762 Peterson, 1994, Changes in mortality after myocardial revascularization in the elderly: The national Medicare experience, Ann Intern Med, 121, 919, 10.7326/0003-4819-121-12-199412150-00003 Pollock, 1992, Independent and incremental prognostic value of tests performed in hierarchical order to evaluate patients with suspected coronary artery disease, Circulation, 85, 237, 10.1161/01.CIR.85.1.237 Pool, 1984, Clinical value of exercise testing in elderly patients, Eur Heart J, 5, 47, 10.1093/eurheartj/5.suppl_E.47 Previtali, 1993, Comparison of dobutamine stress echocardiography, dipyridamole stress echocardiography and exercise stress testing for diagnosis of coronary artery disease, Am J Cardiol, 72, 865, 10.1016/0002-9149(93)91097-2 Quinones, 1992, Exercise echocardiography versus thallium- 201 single photon emmission computed tomography in the evaluation of coronary artery disease: Analysis of 292 patients, Circulation, 85, 1026, 10.1161/01.CIR.85.3.1026 Ribisl, 1992, Angiographic patterns and severe coronary artery disease: Exercise test correlates, Arch Intern Med, 152, 1618, 10.1001/archinte.1992.00400200056010 Rodeheffer, 1984, Exercise cardiac output is maintained with advancing age in healthy human subjects: Cardiac dilatation and increased stroke volume compensate for a diminished heart rate, Circulation, 69, 203, 10.1161/01.CIR.69.2.203 Ryan, 1993, Detection of coronary artery disease with upright bicycle exercise echocardiography, J Am Soc Echocardiogr, 6, 186, 10.1016/S0894-7317(14)80489-6 Ryan, 1986, Risk stratification after acute myocardial infarction by means of exercise two-dimensional echocardiography, Am Heart J, 114, 1305, 10.1016/0002-8703(87)90530-8 Samek, 1984, Exercise testing in elderly patients with coronary artery disease, Eur Heart J, 5, 69, 10.1093/eurheartj/5.suppl_E.69 Sanmarco, 1980, Abnormal blood pressure response and marked ischemic ST segment depression as predictors of severe coronary artery disease, Circulation, 61, 572, 10.1161/01.CIR.61.3.572 Schulman, 1992, Age-related decline in left ventricular filling at rest and exercise, Am J Physiol, 263, H1932 Seals, 1984, Endurance training in older men and women, I: Cardiovascular response to exercise, J Appl Physiol, 57, 1024, 10.1152/jappl.1984.57.4.1024 Shaw, 1992, Prognostic value of dipyridamole thallium-201 imaging in elderly patients, J Am Coll Cardiol, 19, 1390, 10.1016/0735-1097(92)90592-B Smith, 1990, Outlook after acute myocardial infarction in the very elderly compared with that in patients aged 65 to 75 years, J Am Coll Cardiol, 16, 784, 10.1016/S0735-1097(10)80322-5 Sox, 1989, The role of exercise testing in screening for coronary artery disease, Ann Intern Med, 110, 456, 10.7326/0003-4819-110-6-456 Stratton, 1994, Cardiovascular responses to exercise: Effects of aging and exercise training in healthy men, Circulation, 89, 1648, 10.1161/01.CIR.89.4.1648 Stratton, 1992, Differences in cardiovascular reponses to isoproterenol in relation to age and exercise training in healthy men, Circulation, 86, 504, 10.1161/01.CIR.86.2.504 Stuart, 1980, National survey of exercise stress testing facilities, Chest, 77, 94, 10.1378/chest.77.1.94 1989, Comparison of invasive and conservative strategies after treatment with intravenous tissue plasminogen activator in acute myocardial infarction, N Engl J Med, 320, 618, 10.1056/NEJM198903093201002 Theroux, 1979, Prognostic value of exercise testing soon after myocardial infarction, N Engl J Med, 66, 991 Travin, 1993, Variables associated with a poor prognosis in patients with an ischemic thallium-201 exercise test, Am Heart J, 125, 335, 10.1016/0002-8703(93)90009-X Turner, 1980, Detection of residual jeopardized mvocardium 3 weeks after myocardial infarction infarction by exercise testing with thallium-201 myocardial scintigraphy, Circulation, 61, 729, 10.1161/01.CIR.61.4.729 U.S. Bureau of the Census: Statistical Abstract of the United States, ed 101. Washington, DC, 1980 Varnauskas, 1988, the European Surgery Study Group: Twelve-year-follow-up in the randomized European Coronary Surgery Study, N Engl J Med, 319, 332, 10.1056/NEJM198808113190603 Weiner, 1979, Exercise stress testing: Correlations among history of angina, ST-segment response and prevalence of coronary-artery disease in the Coronary Artery Surgery Study (CASS), N Engl J Med, 301, 230, 10.1056/NEJM197908023010502 Weiner, 1980, Identification of patients with left main and three vessel coronary artery disease with clinical and exercise test variables, Am J Cardiol, 46, 21, 10.1016/0002-9149(80)90600-1 Weiner, 1986, The role of exercise testing in identifying patients with improved survival after coronary artery bypass surgery, J Am Coll Cardiol, 8, 741, 10.1016/S0735-1097(86)80412-0 Zhu, 1994, Predischarge exercise radionuclide angiography in predicting multivessel coronary artery disease and subsequent cardiac events after thrombolytic therapy for acute myocardial infarction, Am J Cardiol, 74, 554, 10.1016/0002-9149(94)90743-9