Streptozotocin-nicotinamide-induced rat model of type 2 diabetes (review)

Akademiai Kiado Zrt. - Tập 101 Số 4 - Trang 408-420 - 2014
Asghar Ghasemi1, Saeedeh Khalifi2, S Jedi1
1Shahid Beheshti University of Medical Sciences Endocrine Physiology Research Center, Research Institute for Endocrine Sciences 24 Parvaneh street Velenjak, Tehran Iran PO box: 19395-4763 Shahid Beheshti University of Medical Sciences Endocrine Research Center, Research Institute for Endocrine Sciences Tehran Iran.
2Shahid Beheshti University of Medical Sciences Department of Medical Laboratory Sciences, Faculty of Paramedical Sciences Tehran Iran.

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Ananda P.K., 2012, Effect of Biophytum sensitivum on streptozotocin and nicotinamide-induced diabetic rats, Asian Pac. J. Trop. Biomed., 2, 31, 10.1016/S2221-1691(11)60185-8

Annadurai T., 2012, Antihyperglycemic and antioxidant effects of a flavanone, naringenin, in streptozotocin-nicotinamide-induced experimental diabetic rats, J. Physiol. Biochem., 68, 307, 10.1007/s13105-011-0142-y

Arulmozhi D.K., 2004, Neonatal streptozotocin-induced rat model of type 2 diabetes mellitus: A glance, Indian J. Pharmacol., 36, 217

Atkins R.C., 2010, Diabetic kidney disease: act now or pay later, Acta Physiol. Hung., 97, 52, 10.1556/APhysiol.97.2010.1.6

Badole S.L., 2013, Cycloart-23-ene-3beta, 25-diol stimulates GLP-1 (7-36) amide secretion in streptozotocin-nicotinamide induced diabetic Sprague Dawley rats: a mechanistic approach, Eur. J. Pharmacol., 698, 470, 10.1016/j.ejphar.2012.10.002

Battell M.L., 1999, Experimental models of diabetes

Bedoya F.J., 1996, N-monomethyl-arginine and nicotinamide prevent streptozotocin-induced double strand DNA break formation in pancreatic rat islets, Experientia, 52, 344, 10.1007/BF01919538

Behme M.T., 1995, Nicotinamide and diabetes prevention, Nutr. Rev., 53, 137, 10.1111/j.1753-4887.1995.tb01538.x

Bennett R.A., 1981, Alkylation of DNA in rat tissues following administration of streptozotocin, Cancer Res., 41, 2786

Bolzan A.D., 2002, Genotoxicity of streptozotocin, Mutat. Res., 512, 121, 10.1016/S1383-5742(02)00044-3

Bonner-Weir S., 2000, Islet growth and development in the adult, J. Mol. Endocrinol., 24, 297, 10.1677/jme.0.0240297

Bonner-Weir S., 2000, Life and death of the pancreatic beta cells, Trends Endocrinol. Metab., 11, 375, 10.1016/S1043-2760(00)00305-2

Bonner-Weir S., 2000, Perspective: Postnatal pancreatic beta cell growth, Endocrinology, 141, 1926, 10.1210/endo.141.6.7567

Bonner-Weir S., 2004, Encyclopedia of Gastroenterology

Broca C., 1999, 4-Hydroxyisoleucine: experimental evidence of its insulinotropic and antidiabetic properties, Am. J. Physiol., 277, E617

Candela S., 1979, Circadian variation of the streptozotocin-diabetogenic effect in mice, Experientia, 35, 1256, 10.1007/BF01963323

Chang K.C., 2006, Arterial stiffening and cardiac hypertrophy in a new rat model of type 2 diabetes, Eur. J. Clin. Invest., 36, 1, 10.1111/j.1365-2362.2006.01588.x

Chang K.C., 2006, Aminoguanidine prevents arterial stiffening in a new rat model of type 2 diabetes, Eur. J. Clin. Invest., 36, 528, 10.1111/j.1365-2362.2006.01672.x

Chatzigeorgiou A., 2009, The use of animal models in the study of diabetes mellitus, In Vivo, 23, 245

Chen D., 2005, Development and application of rodent models for type 2 diabetes, Diabetes Obes. Metab., 7, 307, 10.1111/j.1463-1326.2004.00392.x

Chen L., 2012, The worldwide epidemiology of type 2 diabetes mellitus-present and future perspectives, Nat. Rev. Endocrinol., 8, 228, 10.1038/nrendo.2011.183

Chi T.C., 2007, Phosphatidylinositol-3-kinase is involved in the antihyperglycemic effect induced by resveratrol in streptozotocin-induced diabetic rats, Life Sci., 80, 1713, 10.1016/j.lfs.2007.02.002

Deeds M.C., 2011, Single dose streptozotocin-induced diabetes: considerations for study design in islet transplantation models, Lab. Anim., 45, 131, 10.1258/la.2010.010090

Eizirik D.L., 1984, Reduced diabetogenic effect of streptozotocin in rats previously adapted to a high-protein, carbohydrate-free diet, Diabetes, 33, 383, 10.2337/diab.33.4.383

Elshal M.F., 2012, Influence of defatted flaxseed diet on insulin sensitivity, vascular permeability and lipid profile in a rat model of type 2 diabetes mellitus, J. Med. Plants Res., 6, 2188

Fierabracci V., 2002, Oral tungstate treatment improves only transiently alteration of glucose metabolism in a new rat model of type 2 diabetes, Endocrine, 19, 177, 10.1385/ENDO:19:2:177

Haluzik M., 2000, The role of nitric oxide in the development of streptozotocin-induced diabetes mellitus: experimental and clinical implications, Physiol. Res., 49, S37

Hu Y.Y., 2013, Experimental models of type 2 diabetic nephropathy, Chin. Med. J. (Engl), 126, 574, 10.3760/cma.j.issn.0366-6999.20120675

Hypponen E., 2004, Micronutrients and the risk of type 1 diabetes: vitamin D, vitamin E, and nicotinamide, Nutr. Rev., 62, 340, 10.1111/j.1753-4887.2004.tb00059.x

Irons B.K., 2014, Drug treatment of type 2 diabetes mellitus in patients for whom metformin is contraindicated, Diabetes Metab. Syndr. Obes., 7, 15, 10.2147/DMSO.S38753

Islam M.S., 2012, Animal Models in Diabetes Research

Junod A., 1969, Diabetogenic action of streptozotocin: relationship of dose to metabolic response, J. Clin. Invest., 48, 2129, 10.1172/JCI106180

Karunanayake E.H., 1976, Streptozotocin: its excretion and metabolism in the rat, Diabetologia, 12, 483, 10.1007/BF01219512

Kim K.A., 2002, IFN gamma/TNF alpha synergism in MHC class II induction: effect of nicotinamide on MHC class II expression but not on islet-cell apoptosis, Diabetologia, 45, 385, 10.1007/s00125-001-0755-8

Krentz A.J., 2005, Oral antidiabetic agents: current role in type 2 diabetes mellitus, Drugs, 65, 385, 10.2165/00003495-200565030-00005

Kuntz E., 2002, Effects of cholecystokinin octapeptide on the exocrine pancreas in a new rat model of type 2 diabetes, Eur. J. Pharmacol., 448, 253, 10.1016/S0014-2999(02)01937-4

L’abbate A., 2007, Beneficial effect of heme oxygenase-1 expression on myocardial ischemia-reperfusion involves an increase in adiponectin in mildly diabetic rats, Am. J. Physiol. Heart Circ. Physiol., 293, H3532, 10.1152/ajpheart.00826.2007

Lenzen S., 2008, The mechanisms of alloxan- and streptozotocin-induced diabetes, Diabetologia, 51, 216, 10.1007/s00125-007-0886-7

Li H.T., 2011, Antihyperglycemic effects of baicalin on streptozotocin — nicotinamide induced diabetic rats, Phytother. Res., 25, 189, 10.1002/ptr.3238

Maiese K., 2009, The vitamin nicotinamide: translating nutrition into clinical care, Molecules, 14, 3446, 10.3390/molecules14093446

Masiello P., 2006, Animal models of type 2 diabetes with reduced pancreatic beta-cell mass, Int. J. Biochem. Cell. Biol., 38, 873, 10.1016/j.biocel.2005.09.007

Masiello P., 1977, Nicotinamide and streptozotocin diabetes in the rat. Factors influencing the effectiveness of the protection, Experientia, 33, 1246, 10.1007/BF01922358

Masiello P., 1998, Experimental NIDDM: development of a new model in adult rats administered streptozotocin and nicotinamide, Diabetes, 47, 224, 10.2337/diab.47.2.224

Murugan P., 2006, Antioxidant effect of tetrahydrocurcumin in streptozotocin-nicotinamide induced diabetic rats, Life Sci., 79, 1720, 10.1016/j.lfs.2006.06.001

Nathan D.M., 2009, Medical management of hyperglycemia in type 2 diabetes: a consensus algorithm for the initiation and adjustment of therapy: a consensus statement of the American Diabetes Association and the European Association for the Study of Diabetes, Diabetes Care, 32, 193, 10.2337/dc08-9025

Novelli M., 2001, Metabolic and functional studies on isolated islets in a new rat model of type 2 diabetes, Mol. Cell. Endocrinol., 175, 57, 10.1016/S0303-7207(01)00400-2

Novelli M., 2004, Alteration of beta-cell constitutive NO synthase activity is involved in the abnormal insulin response to arginine in a new rat model of type 2 diabetes, Mol. Cell. Endocrinol., 219, 77, 10.1016/j.mce.2004.01.010

Ortiz-Andrade R.R., 2008, Antidiabetic and toxicological evaluations of naringenin in normoglycaemic and NIDDM rat models and its implications on extra-pancreatic glucose regulation, Diabetes Obes. Metab., 10, 1097, 10.1111/j.1463-1326.2008.00869.x

Ortiz P.A., 2002, Role of nitric oxide in the regulation of nephron transport, Am. J. Physiol. Renal. Physiol., 282, F777, 10.1152/ajprenal.00334.2001

Palsamy P., 2010, Resveratrol attenuates hyperglycemia-mediated oxidative stress, proinflammatory cytokines and protects hepatocytes ultrastructure in streptozotocin-nicotinamide-induced experimental diabetic rats, Chem. Biol. Interact., 186, 200, 10.1016/j.cbi.2010.03.028

Palsamy P., 2009, Modulatory effects of resveratrol on attenuating the key enzymes activities of carbohydrate metabolism in streptozotocin-nicotinamide-induced diabetic rats, Chem. Biol. Interact., 179, 356, 10.1016/j.cbi.2008.11.008

Palsamy P., 2010, Ameliorative potential of resveratrol on proinflammatory cytokines, hyperglycemia mediated oxidative stress, and pancreatic beta-cell dysfunction in streptozotocin-nicotinamide-induced diabetic rats, J. Cell. Physiol., 224, 423, 10.1002/jcp.22138

Palsamy P., 2011, Resveratrol protects diabetic kidney by attenuating hyperglycemia-mediated oxidative stress and renal inflammatory cytokines via Nrf2-Keap1 signaling, Biochim. Biophys. Acta, 1812, 719, 10.1016/j.bbadis.2011.03.008

Pandya K.G., 2010, Comparative study of the binding characteristics to and inhibitory potencies towards PARP and in vivo antidiabetogenic potencies of taurine, 3-aminobenzamide and nicotinamide, J. Biomed. Sci., 17, S16, 10.1186/1423-0127-17-S1-S16

Pari L., 2010, Comparative and combined effect of chlorogenic acid and tetrahydrocurcumin on antioxidant disparities in chemical induced experimental diabetes, Mol. Cell. Biochem., 341, 109, 10.1007/s11010-010-0442-5

Pari L., 2009, Beneficial effects of thymoquinone on hepatic key enzymes in streptozotocin-nicotinamide induced diabetic rats, Life Sci., 85, 830, 10.1016/j.lfs.2009.10.021

Pari L., 2007, Beneficial effect of succinic acid monoethyl ester on erythrocyte membrane bound enzymes and antioxidant status in streptozotocin-nicotinamide induced type 2 diabetes, Chem. Biol. Interact., 169, 15, 10.1016/j.cbi.2007.04.010

Pari L., 2006, Effect of pterostilbene on hepatic key enzymes of glucose metabolism in streptozotocin- and nicotinamide-induced diabetic rats, Life Sci., 79, 641, 10.1016/j.lfs.2006.02.036

Pari L., 2010, Antihyperglycemic effect of diosmin on hepatic key enzymes of carbohydrate metabolism in streptozotocin-nicotinamide-induced diabetic rats, Biomed. Pharmacother., 64, 477, 10.1016/j.biopha.2010.02.001

Pari L., 2010, Efficacy of naringin on hepatic enzymes of carbohydrate metabolism in streptozotocin-nicotinamide induced type 2 diabetic rats, Int. J. Pharm. Biol. Arch., 1, 280

Pierre W., 2012, Hypoglycemic and hypolipidemic effects of Bersama engleriana leaves in nicotinamide/streptozotocin-induced type 2 diabetic rats, BMC Complement Altern. Med., 12, 264, 10.1186/1472-6882-12-264

Pitkin R.M., 1970, Diabetogenic effects of streptozotocin in rhesus monkeys, Diabetes, 19, 85, 10.2337/diab.19.2.85

Pociot F., 1993, Nicotinamide biological actions and therapeutic potential in diabetes prevention., Diabetologia, 36, 574, 10.1007/BF02743277

Rabbani S.I., 2009, Inhibitory effect of glimepiride on nicotinamide-streptozotocin induced nuclear damages and sperm abnormality in diabetic Wistar rats, Indian J. Exp. Biol., 47, 804

Rajarajeswari N., 2011, Antioxidant role of coumarin on streptozotocin-nicotinamide-induced type 2 diabetic rats, J. Biochem. Mol. Toxicol., 25, 355, 10.1002/jbt.20395

Reed M.J., 2000, A new rat model of type 2 diabetes: the fat-fed, streptozotocin-treated rat, Metabolism, 49, 1390, 10.1053/meta.2000.17721

Rees D.A., 2005, Animal models of diabetes mellitus, Diabet. Med., 22, 359, 10.1111/j.1464-5491.2005.01499.x

Rodrigues B., 1999, Experimental Models of Diabetes

Sharma A.K., 2012, Sitagliptin, sitagliptin and metformin, or sitagliptin and amitriptyline attenuate streptozotocin-nicotinamide induced diabetic neuropathy in rats, J. Biomed. Res., 26, 200, 10.7555/JBR.26.20110054

Sheela N., 2013, Effect of silymarin on streptozotocin-nicotinamide-induced type 2 diabetic nephropathy in rats, Iran J. Kidney Dis., 7, 117

Shirwaikar A., 2006, Effect of aqueous bark extract of Garuga pinnata Roxb. in streptozotocinnicotinamide induced type-II diabetes mellitus, J. Ethnopharmacol., 107, 285, 10.1016/j.jep.2006.03.012

Siddiqui B.S., 2014, Two new compounds from the aerial parts of Bergenia himalaica Boriss and their anti-hyperglycemic effect in streptozotocin-nicotinamide induced diabetic rats, J. Ethnopharmacol., 152, 561, 10.1016/j.jep.2014.02.002

Srinivasan K., 2007, Animal models in type 2 diabetes research: an overview, Indian J. Med. Res., 125, 451

Su H.C., 2006, Resveratrol, a red wine antioxidant, possesses an insulin-like effect in streptozotocin-induced diabetic rats, Am. J. Physiol. Endocrinol. Metab., 290, E1339, 10.1152/ajpendo.00487.2005

Szkudelska K., 2014, Adipocyte dysfunction in rats with streptozotocin-nicotinamide-induced diabetes, Int. J. Exp. Pathol., 95, 86, 10.1111/iep.12073

Szkudelski T., 2001, The mechanism of alloxan and streptozotocin action in B cells of the rat pancreas, Physiol. Res., 50, 537

Szkudelski T., 2012, Streptozotocin-nicotinamide-induced diabetes in the rat. Characteristics of the experimental model, Exp. Biol. Med. (Maywood), 237, 481, 10.1258/ebm.2012.011372

Taha H., 2014, Upregulation of insulin secretion and downregulation of pro-inflammatory cytokines, oxidative stress and hyperglycemia in STZ-nicotinamide-induced type 2 diabetic rats by Pseuduvaria monticola bark extract, Food Chem. Toxicol., 66, 295, 10.1016/j.fct.2014.01.054

Tay Y.C., 2005, Can murine diabetic nephropathy be separated from superimposed acute renal failure?, Kidney Int., 68, 391, 10.1111/j.1523-1755.2005.00405.x

Torres-Piedra M., 2010, A comparative study of flavonoid analogues on streptozotocin-nicotinamide induced diabetic rats: quercetin as a potential antidiabetic agent acting via 11beta-hydroxysteroid dehydrogenase type 1 inhibition, Eur. J. Med. Chem., 45, 2606, 10.1016/j.ejmech.2010.02.049

Weng Y., 2014, Antihyperglycemic, hypolipidemic and antioxidant activities of total saponins extracted from Aralia taibaiensis in experimental type 2 diabetic rats, J. Ethnopharmacol., 152, 553, 10.1016/j.jep.2014.02.001