Strategies Toward the Catalyst-Free α-C–H Functionalizations of Tertiary Amines

Springer Science and Business Media LLC - Tập 381 - Trang 1-27 - 2023
Mohit L. Deb1, Pranjal K. Baruah1
1Department of Applied Sciences, GUIST, Gauhati University, Guwahati, India

Tóm tắt

α-C–H functionalization of tertiary amines has been a highly studied field for the past two decades because several important nitrogen containing heterocycles or compounds can be synthesized through this strategy. Though transition metal catalysts and some metal-free catalysts are mainly used for these reactions, a few catalyst-free reactions have recently been efficiently performed. Catalyst-free reactions are cost-effective, less sensitive to air/moisture, easier to operate, have a simple purification process, and are relatively environment-friendly. In this article, we have summarized all the α-C–H functionalization reactions of tertiary amines performed without using any external catalysts. The content of this article will undoubtedly encourage readers to do more work in this area.

Tài liệu tham khảo

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