Stimulation of adipogenesis in fibroblasts by PPARγ2, a lipid-activated transcription factor

Ailhaud, 1992, Cellular and molecular aspects of adipose tissue development, Annu. Rev. Nutr., 12, 207, 10.1146/annurev.nu.12.070192.001231

Bennet, 1990, Epidemiology of diabetes mellitus, 357

Brandes, 1987, Adipocyte conversion of cultured 3T3-L1 preadipocytes by benzafibrate, Life Sci., 40, 935, 10.1016/0024-3205(87)90312-2

Chawla, 1994, Peroxisome proliferator and retinoid signalling pathways co-regulate preadipocyte phenotype and survival, 91, 1786

Chen, 1993, Identification of two mPPAR related receptors and evidence for the existence of five subfamily members, Biochem. Biophys. Res. Commun., 196, 671, 10.1006/bbrc.1993.2302

Chirgwin, 1979, Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease, Biochemistry, 18, 5294, 10.1021/bi00591a005

Christy, 1989, Differentiation-induced gene expression in 3T3-L1 preadipocytes: CCAAT/enhancer binding protein interacts with and activates the promoters of two adipocyte-specific genes, Genes Dev., 3, 1323, 10.1101/gad.3.9.1323

Dreyer, 1992, Control of the peroxisomal β-oxidation pathway by a novel family of nuclear hormone réceptors, Cell, 68, 879, 10.1016/0092-8674(92)90031-7

Enerback, 1992, Characterization of the human lipoprotein lipase (LPL) promoter: evidence of two cis-regulatory regions, LP-α and LP-β, of importance for the differentiation-linked induction of the LPL gene during adipogenesis, Mol. Cell. Biol., 12, 4622, 10.1128/MCB.12.10.4622

Fineberg, 1984, A technique for radiolabeling DNA restriction fragments to high specific activity, Anal. Biochem., 137, 266, 10.1016/0003-2697(84)90381-6

Freytag, 1992, Reciprocal regulation of adipogenesis by Myc and CEBPα, Science, 256, 379, 10.1126/science.256.5055.379

Freytag, 1994, Ectopic expression of the CCAAT/enhancer-binding protein a promotes the adipogenic program in a variety of mouse fibroblastic cells, Genes Dev., 8, 1654, 10.1101/gad.8.14.1654

Friedman, 1989, CCAAT/enhancer binding protein activates the promoter of the serum albumin gene in cultured hepatoma cells, Genes Dev., 3, 1314, 10.1101/gad.3.9.1314

Gharbi-Chihi, 1993, Increase of adipocyte differentiation by hypolipidemic fibrate drugs in Ob 17 preadipocytes: requirement for thyroid hormones, Biochem. Biophys. Acta, 1177, 8, 10.1016/0167-4889(93)90150-N

Giguere, 1994, Isoform-specific amino terminal domains dictate DNA binding properties of ROR-α, a novel family of orphan hormone nuclear receptors, Genes Dev., 8, 538, 10.1101/gad.8.5.538

Gottlicher, 1992, Fatty acids activate a chimera of the clofibric acid-activated receptor and the glucocorticoid receptor, 89, 4653

Graves, 1991, Identification of a potent adipocyte-specific enhancer: involvement of an NF-1-like factor, Genes Dev., 5, 428, 10.1101/gad.5.3.428

Graves, 1992, Analysis of a tissue-specific enhancer: ARF6 regulates adipogenic gene expression, Mol. Cell. Biol., 12, 1202, 10.1128/MCB.12.3.1202

Green, 1974, Sublines of mouse 3T3 cells that accumulate lipid, Cell, 1, 113, 10.1016/0092-8674(74)90126-3

Green, 1976, Spontaneous heritable changes leading to increased adipose conversion in 3T3 cells, Cell, 7, 105, 10.1016/0092-8674(76)90260-9

Herrera, 1989, A direct role for CEBP and the AP-1 binding site in gene expression linked to adipocyte differentiation, Mol. Cell. Biol., 9, 5331, 10.1128/MCB.9.12.5331

Isseman, 1990, Activation of a member of the steroid hormone receptor superfamily by peroxisome proliferators, Nature, 347, 645, 10.1038/347645a0

Kastner, 1990, Two distinct oestrogen-regulated promoters generate transcripts encoding the two functionally distinct human progesterone receptor forms A and B, EMBO J., 9, 1603, 10.1002/j.1460-2075.1990.tb08280.x

Keller, 1993, Peroxisome proliferator-activated receptors: a link between endocrinology and nutrition?, Trends Endocrinol. Metab., 4, 291, 10.1016/1043-2760(93)90048-J

Keller, 1993, Fatty acids and retinoids control lipid metabolism through activation of peroxisome proliferator-activated receptor-retinoid X receptor heterodimers, 90, 2160

Kliewer, 1992, Retinoid X receptor interacts with nuclear receptors in retinoic acid, thyroid hormone, and vitamin D3 signalling, Nature, 355, 446, 10.1038/355446a0

Kliewer, 1992, Convergence of 9-cis retinoic acid and peroxisome proliferator signalling pathways through heterodimer formation of their receptors, Nature, 358, 771, 10.1038/358771a0

Kliewer, 1994, Differential expression and activation of a family of murine peroxisome proliferator-activated receptors, 91, 7355

Korman, 1987, Expression of human class II major histocompatibility complex antigens using retrovirus vectors, 84, 2150

Laborda, 1991, 36B4 cDNA used as an estradiol-independent mRNA control is the cDNA for human acidic ribosomal phosphoprotein PO, Nucl. Acids Res., 19, 3998, 10.1093/nar/19.14.3998

Lin, 1994, CCAATT/enhancer binding protein α is sufficient to initiate the 3T3-L1 adipocyte differentiation program, 91, 8757

Mangelsdorf, 1990, Nuclear receptor that identifies a novel retinoic acid response pathway, Nature, 345, 224, 10.1038/345224a0

Maniatis, 1989

McGrane, 1990, Metabolic effects of developmental, tissue-, and cell-specific expression of a chimeric phosphoenolpyruvate carboxykinase (GTP)/bovine growth hormone gene in transgenic mice, J. Biol. Chem., 265, 22371, 10.1016/S0021-9258(18)45715-8

Morgenstern, 1990, Advanced mammalian gene transfer: high titre retroviral vectors with multiple drug selection markers and a complementary helper-free packaging cell line, Nucl. Acids Res., 18, 3587, 10.1093/nar/18.12.3587

Nagpal, 1992, Promoter context- and response element-dependent specificity of the transcriptional activation and modulating functions of retinoic acid receptors, Cell, 70, 1007, 10.1016/0092-8674(92)90250-G

Park, 1990, The role of the CAAT/enhancer-binding protein in the transcriptional regulation of the gene for phosphoenolpyruvate carboxykinase (GTP), Mol. Cell. Biol., 10, 6264, 10.1128/MCB.10.12.6264

Pear, 1993, Production of high titre, helper-free retroviruses by transient transfection, 90, 8392

Ross, 1990, A fat-specific enhancer is the primary determinant of gene expression for adipocyte P2 in vivo, 87, 9590

Samuelsson, 1991, The CAAT/enhancer binding protein and its role in adipocyte differentiation: evidence for direct involvement in terminal adipocyte development, EMBO J., 10, 3787, 10.1002/j.1460-2075.1991.tb04948.x

Schmidt, 1992, Identification of a new member of the steroid hormone receptor superfamily that is activated by a peroxisome proliferator and fatty acid, Mol. Endocrinol., 6, 1634, 10.1210/me.6.10.1634

Short, 1992, Tissue-specific, developmental, hormonal and dietary regulation of a rat phosphoenolpyruvate carboxykinase-human growth hormone fusion gene in transgenic mice, Mol. Cell. Biol., 12, 1007, 10.1128/MCB.12.3.1007

Tontonoz, 1993, ADD1: a novel helix-loop-helix transcription factor associated with adipocyte determination and differentiation, Mol. Cell. Biol., 13, 4753, 10.1128/MCB.13.8.4753

Tontonoz, 1994, mPPARγ2: tissue-specific regulator of an adipocyte enhancer, Genes Dev., 8, 1224, 10.1101/gad.8.10.1224

Tontonoz, 1995, PPARγ2 regulates adipose expression of the phosphoenolpyruvate carboxykinase gene, Mol. Cell. Biol., 10.1128/MCB.15.1.351

Tontonoz, 1995, Adipocyte-specific transcription factor ARF6 is a heterodimeric complex of two nuclear hormone receptors, PPARγ and RXRα, Nucl. Acids Res.

Umek, 1991, CCAAT/enhancer binding protein: a component of a differentiation switch, Science, 251, 288, 10.1126/science.1987644

Wahli, 1991, Superfamily of steroid nuclear receptors: positive and negative regulators of gene expression, FASEB J., 5, 2243, 10.1096/fasebj.5.9.1860615

Zhu, 1993, Cloning of a new member of the peroxisome proliferator-activated receptor gene family from mouse liver, J. Biol. Chem., 268, 26817, 10.1016/S0021-9258(19)74184-2