Steroids, neuroactive steroids and neurosteroids in psychopathology
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Agnati, 2000, Volume transmission revisited, vol. 125
Akunne, 2001, Neuropharmacological profile of a selective sigma ligand, igmesine: a potential antidepressant, Neuropharmacology, 41, 138, 10.1016/S0028-3908(01)00049-1
Akwa, 1999, The amygdala mediates the anxiolytic-like effect of the neurosteroid allopregnanolone in rat, Behav. Brain Res., 106, 119, 10.1016/S0166-4328(99)00101-1
Aldred, 1999, Localisation of dehydroepiandrosterone sulphotransferase in rat brain, Brain Res. Bull., 48, 291, 10.1016/S0361-9230(98)00172-5
Allera, 1992, Glucocorticoid-recognizing and glucocorticoid-effector sites in rat liver plasma membrane. Kinetics of corticosterone uptake by isolated membrane vehicles: 2. Comparative influx and efflux, J. Steroid Biochem., 42, 757, 10.1016/0960-0760(92)90116-Z
Avanzino, 1983, Actions of microelectrophoretically applied glucocorticoid hormones on reticular neurons in the rat, Neurosci. Lett., 38, 45, 10.1016/0304-3940(83)90108-8
Azmintia, 1995, Anatomy, cell biology, and plasticity of the serotonergic system
Backström, 1986, Brain excitability, steroid hormone and menstrual cycle, 137
Backström, 1986, The human corpus luteum secretes 5 α pregnane-3, 20-dione, Acta Endocrinol., 111, 116, 10.1530/acta.0.1110116
Barbaccia, 1996, Time-dependent changes in rat brain neuroactive steroid concentrations and GABA-A receptor function after acute stress, Neuroendocrinology, 63, 166, 10.1159/000126953
Barbaccia, 1999, Ethanol markedly increases GABAergic neurosteroids in alcohol-preferring rats, Eur. J. Pharmacol., 384, R1, 10.1016/S0014-2999(99)00678-0
Barbaccia, 2001, Clozapine, but not haloperidol, increases brain concentrations of neuroactive steroids in the rat, Neuropsychopharmacology, 25, 489, 10.1016/S0893-133X(01)00254-8
Baulieu, 1981, Steroid hormones in the brain: several mechanisms, 3
Baulieu, 1998, Neurosteroids: a novel function of the brain, Psychoneuroendocrinology, 23, 963, 10.1016/S0306-4530(98)00071-7
Beck, 1979
Belanoff, 2002, An open label trial of C-1073 (Mifepristone) for psychotic major depression, Biol. Psychiatry, 52, 386, 10.1016/S0006-3223(02)01432-4
Belelli, 1989, Anticonvulsant profile of the progesterone metabolite 3α-hydroxy 5 α pregnan-20-one, Eur. J. Pharmacol., 166, 325, 10.1016/0014-2999(89)90077-0
Bennet, 1991, Serum corticosterone level predicts the magnitude of hippocampal primed burst potentiation and depression in urethane-anesthetized rats, Psychobiology, 19, 301, 10.3758/BF03332083
Bentley, 1972
Berr, 1996, Relationship of dehydroepiandrosterone sulfate in the elderly with functional, psychological, and mental status, and short-term mentality: a French community-based study, Proc. Natl. Acad. Sci. U. S. A., 93, 13410, 10.1073/pnas.93.23.13410
Bhagwagar, 2004, Increased brain GABA concentrations following acute administration of a selective serotonin reuptake inhibitor, Am. J. Psychiatryy, 161, 368, 10.1176/appi.ajp.161.2.368
Bicikova, 2000, Serum concentrations of some neuroactive steroids in women suffering from mixed anxiety–depressive disorder, Neurochem. Res., 25, 1623, 10.1023/A:1026622704704
Biggio, 2001, GABAA-receptor plasticity during long-term exposure to and withdrawal from progesterone, Int. Rev. Neurobiol., 46, 207, 10.1016/S0074-7742(01)46064-8
Birmingham, 1961, The identification of the Porter Silber chromogen secreted by the rat adrenal, J. Biol. Chem., 236, 1661, 10.1016/S0021-9258(19)63281-3
Bitran, 1993, Anxiolytic effect of progesterone is associated with increases in cortical allopregnanolone and GABAA receptor function, Pharmacol. Biochem. Behav., 45, 423, 10.1016/0091-3057(93)90260-Z
Bitran, 2000, The neurosteroid pregnanolone prevents the anxiogenic-like effect of inescapable shock in the rat, Psychopharmacology, 151, 31, 10.1007/s002130000472
Bliss, 1993, A synaptic model of memory: long-term potentiation in the hippocampus, Nature, 361, 31, 10.1038/361031a0
Bloch, 1999, Dehydroepiandrosterone treatment of midlife dysthymia, Biol. Psychiatry, 45, 1533, 10.1016/S0006-3223(99)00066-9
Bonanno, 1987, A carrier for GABA uptake exists on noraderenaline nerve endings in selective rat brain areas but not on serotonin terminals, J. Neural Transm., 69, 59, 10.1007/BF01244097
Bonanno, 1987, Release-regulating GABAA receptors are present on noradrenergic nerve terminals in selective areas of the rat brain, Synapse, 1, 254, 10.1002/syn.890010306
Bower, 1983, Affect and cognition, Philos. Trans. R. Soc. Lond., B Biol. Sci., 302, 387, 10.1098/rstb.1983.0062
Brambilla, 2003, Neurosteroids and panic disorder, Psychiatry Res., 118, 107, 10.1016/S0165-1781(03)00077-5
Brinton, 1994, The neurosteroid 3α-hydroxy-5α pregnan-20-one induces cytoarchitectural regression in cultured fetal hippocampal nucleus, J. Neurosci., 14, 2763, 10.1523/JNEUROSCI.14-05-02763.1994
Broekhoven van, 2003, Neurosteroids in depression: a review, Psychopharmacology (Berl.), 165, 97, 10.1007/s00213-002-1257-1
Brot, 1997, The anxiolytic-like effects of the neurosteroid allopregnanolone: interactions with GABA (A) receptors, Eur. J. Pharmacol., 325, 1, 10.1016/S0014-2999(97)00096-4
Brown, 2001, Role of the peripheral-type benzodiazepine receptor in adrenal brain steroidogenesis, vol. 46, 117
Brussaard, 2003, Conditional regulation of neurosteroid sensitivity of GABAA receptors, Ann. N.Y. Acad. Sci., 1007, 29, 10.1196/annals.1286.003
Bullock, 1997, Neurosteroids modulate nicotinic receptor function in mouse striatal and thalamic synaptosomes, J. Neurochem., 68, 2412, 10.1046/j.1471-4159.1997.68062412.x
Castren, 2004, Neurotropic effects of antidepressant drugs, Curr. Opin. Pharmacol., 4, 58, 10.1016/j.coph.2003.10.004
Cheny, 1995, Gas chromatographic-mass fragmentographic quantitation of 3 alpha-hydroxy-5 alpha-pregnan-20-one (allopregnanolone) and its precursors in blood and brain of adrenalectomized and castrated rats, J. Neurosci., 15, 4641, 10.1523/JNEUROSCI.15-06-04641.1995
Cleghorn, 1951, Adrenal cortical insufficiency: psychological and neurological observations, Can. Med. Assoc. J., 65, 449
Cohen, 1980, Cushing's syndrome: a psychiatric study of 29 patients, Br. J. Psychiatry, 136, 120, 10.1192/bjp.136.2.120
Compagnone, 1998, Dehydroepiandrosterone: a potential signalling molecule for neocortical organization during development, Proc. Natl. Acad. Sci. U. S. A., 95, 4678, 10.1073/pnas.95.8.4678
Crawley, 1986, Anxiolytic activity of an endogenous adrenal steroid, Brain Res., 398, 382, 10.1016/0006-8993(86)91500-3
Csaba, 1980, Phylogeny and ontogeny of hormone receptors: the selection theory of receptor formation and hormonal imprinting, Biol. Rev., 55, 47, 10.1111/j.1469-185X.1980.tb00687.x
Cushing, 1913, Psychiatric disturbances associated with disorders of the ductless glands, Am. J. Insanity, 69, 965
Cushing, 1932, The basophil adenomas of the pituitary body and their clinical manifestations, Bull. John Hopkins Hosp., 50, 137
Czeh, 2001, Stress induced changes in cerebral metabolites, hippocampal volume, and cell proliferation are prevented by antidepressant treatment with tianeptine, Proc. Natl. Acad. Sci. U. S. A., 98, 12796, 10.1073/pnas.211427898
Damianisch, 2001, The influence of subchronic administration of the neurosteroid allopregnanolone on sleep in the rat, Neuropsychopharmacology, 25, 576, 10.1016/S0893-133X(01)00242-1
Danielli, 1953, Postscript. On some physical and chemical aspects of evolution
Daufeldt, 2003, Membrane-initiated steroid signalling (MISS): genomic steroid action starts at the plasma membrane, J. Steroid Biochem., 85, 9, 10.1016/S0960-0760(03)00141-9
De Kloet, 1998, Brain corticosteroid receptor balance in health and disease, Endocr. Rev., 19, 269, 10.1210/er.19.3.269
De Kloet, 1999, Stress and cognition: are corticosteroids good or bad guys?, Trends Neurosci., 22, 422, 10.1016/S0166-2236(99)01438-1
Deldin, 2001, A slow wave investigation of working memory biases in mood disorders, J. Abnorm. Psychology, 110, 267, 10.1037/0021-843X.110.2.267
Delgado, 2000, Depression: the case for a monoamine deficiency, J. Clin. Psychiatry, 61, 7
Delgado, 2000, Role of norepinephrine in depression, J. Clin. Psychiatry, 61, 5
Demirgoren, 1991, Receptor binding and electrophysiological effects of dehydroepiandrosterone sulfate, an antagonist of the GABAA receptor, Neuroscience, 45, 127, 10.1016/0306-4522(91)90109-2
Demey-Ponsart, 1987, Diagnostic performance of basal free cortisol/18 hydroxy-deoxycorticosterone (18OHDOC) ratio in endogenous depression: comparison with Dexamethasone Suppression Test, Biol. Psychiatry, 22, 947, 10.1016/0006-3223(87)90004-7
De Nicola, 2003, Steroid effecs on glial cells. Detrimental or protective for spinal cord injury?, Ann. N.Y. Acad. Sci., 1007, 317, 10.1196/annals.1286.030
De Quervain, 1998, Stress and glucocorticoids impair retrieval of long-term spatial memory, Nature, 394, 787, 10.1038/29542
Diagnostic and Statistical Manual of Mental Disorders, 4th ed., 1994. American Psychiatric Association, Washington, D.C.
Diamond, 1994, Psychological stress repeatedly blocks hippocampal primed burst potentiation in behaving rats, Behav. Brain Res., 62, 1, 10.1016/0166-4328(94)90032-9
Dismukes, 1997, New look at the aminergic nervous system, Nature, 209, 557
Do-Rego, 2000, Gamma-aminobutyric acid, acting through gamma-aminobutyric acid type A receptors, inhibits the biosynthesis of neurosteroids in the frog hypothalamus, Proc. Natl. Acad. Sci. U. S. A., 97, 13925, 10.1073/pnas.240269897
Drake, 1968, Neuropsychiatric-like symptomatology of Addison's disease: a review, Am. J. Med. Sci., 81, 106
Dubrovsky, 1993, Adrenal steroids and the pathophysiology of a subset of depressive patients, J. Psychiatry Neurosci., 18, 1
Dubrovsky, 1995, Fundamental neuroscience and the classification of psychiatric disorders, Neurosci. Biobehav. Rev., 19, 511, 10.1016/0149-7634(94)00054-5
Dubrovsky, 1997, Natural steroids counteracting some actions of putative depressogenic steroids on the central nervous system. Potential therapeutic benefits, Med. Hypotheses, 49, 51, 10.1016/S0306-9877(97)90252-8
Dubrovsky, 2000, The specificity of stress responses to different nocuous stimuli: neurosteroids and depression, Brain Res. Bull., 51, 443, 10.1016/S0361-9230(99)00269-5
Dubrovsky, 2001, Dynamics of neural networks. A proposed mechanism(s) to account for changes in clinical symptoms through time in patients with psychotic diseases, Med. Hypotheses, 57, 439, 10.1054/mehy.2001.1353
Dubrovsky, 2002, Evolutionary psychiatry. Adaptationists and non-adaptationists conceptualization, Prog. Neuro-psychopharmacol. Biol. Psychiatry, 27, 1, 10.1016/S0278-5846(01)00243-3
Dubrovsky, 2004, Evolutionary psychiatry
Dubrovsky, 1982, Effects of deoxycorticosterone and its ring A-reduced derivatives on the nervous system, Exp. Neurol., 78, 728, 10.1016/0014-4886(82)90087-5
Dubrovsky, 1985, Effects of corticosterone and 5α dihydrocorticosterone on brain excitability in the rat, Neurosci. Res., 14, 118
Dubrovsky, 1986, Effects of 18-hydroxydeoxycorticosterone on central nervous system excitability, Experientia, 42, 1027, 10.1007/BF01940717
Dubrovsky, 1987, Effects of 5α dihydro-corticosterone on evoked potentials and long-term potentiation, Brain Res. Bull., 19, 635, 10.1016/0361-9230(87)90049-9
Dubrovsky, 1990, Early and late effects of steroid hormones on the central nervous system, vol. 153, 240
Dubrovsky, 1993, Effects of adrenocrtical steroids on long term potentiation in the limbic system. Basic mechanisms and behavioral consequences, Cell. Mol. Neurobiol., 13, 399, 10.1007/BF00711580
Dubrovsky, 1996, Electrophysiological effects of steroid hormones on nervous systems, 89
Dubrovsky, 2002, Oxytocin induces long term depression on the rat dentate gyrus. ATPase and ectoprotein kinase mediation, Brain Res. Bull., 58, 141, 10.1016/S0361-9230(01)00748-1
Dubrovsky, 2004, Effects of the active neurosteroid THDOC on long term potentiation. Implications for depression, Prog. Neuro-psychopharmacol. Biol. Psychiatry, 28, 1029, 10.1016/j.pnpbp.2004.06.001
Dunbar, 1984, Depression, recognition-memory and hedonic tone. A signal detection analysis, Br. J. Psychiatry, 144, 365, 10.1192/bjp.144.4.376
Edwards, 1980, Effects of bilateral adrenalectomy on the induction of learned helplessness behavior, Neuropsychopharmacology, 3, 109
Erhart-Bornstein, 1998, Intraadrenal interactions in the regulation of adrenocortical steroidogenesis, Endocr. Rev., 19, 101, 10.1210/er.19.2.101
Fabian, 2001, Endogenous concentrations of DHEA and DHEA-S decrease with remission of depression in older adults, Biol. Psychiatry, 50, 767, 10.1016/S0006-3223(01)01198-2
Ferrarra, 2001, Increased expression of the neuropeptide Y receptor Y (1) gene in the medial amygdala of transgenic mice induced by long-term treatment with progesterone or allopregnanolone, J. Neurochem., 79, 417, 10.1046/j.1471-4159.2001.00559.x
ffrench-Mullen, 1994, Neurosteroids modulate calcium currents in hippocampal CA1 neurons via a pertussis toxin-sensitive G-protein coupled mechanism, J. Neurosci., 14, 1963, 10.1523/JNEUROSCI.14-04-01963.1994
File, 1988, Myoclonic seizures in the mouse induced by alphaxolone and related steroid anaesthetics, J. Pharm. Pharmacol., 40, 57, 10.1111/j.2042-7158.1988.tb05152.x
Filipini, 1991, Modulatory actions of adrenal steroids on limbic structures, J. Steroid Biochem. Mol. Biol., 39, 245, 10.1016/0960-0760(91)90070-L
Filipini, 1991, Effects of adrenal steroids and their reduced metabolites on hippocampal long-term potentiation, J. Steroid Biochem. Mol. Biol., 40, 87, 10.1016/0960-0760(91)90171-Z
Finn, 2004, The role of pregnane neurosteroids in ethanol withdrawal: behavioral genetic approaches, Pharmacol. Ther., 101, 91, 10.1016/j.pharmthera.2003.10.006
Fleshner, 1997, DHEA-S selectively impairs contextual-fear conditioning: support for the antiglucocorticoid hypothesis, Behav. Neurosci., 111, 512, 10.1037/0735-7044.111.3.512
Flood, 1988, Dehydroepiandrosterone sulfate improves memory in aging mice, Brain Res., 448, 178, 10.1016/0006-8993(88)91116-X
Flood, 1992, Memory-enhancing effects in male mice of pregnenolone and steroids metabolically derived from it, Proc. Natl. Acad. Sci. U. S. A., 89, 1567, 10.1073/pnas.89.5.1567
Foote, 1995, Pharmacological and physiology of central noradrenergic systems, 335
Frank, 2000, Neuroprotective effects of allopregnenolone on hippocampal irreversible neurotoxicity in vitro, Prog. Neuro-psychopharmacol. Biol. Psychiatry, 24, 1117, 10.1016/S0278-5846(00)00124-X
Freeman, 1997, Neurohumoral brain dynamics of social group formation, Ann. N.Y. Acad. Sci., 807, 501, 10.1111/j.1749-6632.1997.tb51951.x
Freeman, 2002, Allopregnanolonelevels and symptom improvement in severe premenstrual syndrome, J. Clin. Psychopharmacol., 22, 516, 10.1097/00004714-200210000-00013
Frye, 1998, Androgenic neurosteroids: anti-seizure effects in an animal model of epilepsy, Psychoneuroendocrinology, 23, 385, 10.1016/S0306-4530(98)00009-2
Frye, 1995, Neurosteroids affect spatial reference, working, and long-term memory of female rats, Neurobiol. Learn. Mem., 64, 83, 10.1006/nlme.1995.1046
Frye, 2001, Testosterone reduces pentylenetetrazone-induced ictal activity in wild type mice but not mice deficient in Type I 5 alpha-reductase, Brain Res., 918, 182, 10.1016/S0006-8993(01)02967-5
Gallagher, 2002, Cortisol/DHEA ratios in depression, Neuropsychopharmacology, 26, 410, 10.1016/S0893-133X(01)00362-1
Genazzani, 1998, Circulating levels of allopregnanolone in humans: gender, age, and endocrine influences, J. Clin. Endocrinol. Metab., 83, 2099, 10.1210/jc.83.6.2099
Gerner, 1981, CSF GABA in normal subjects and patients with depression, schizophrenia, mania and anorexia nervosa, Am. J. Psychiatryy, 138, 1098, 10.1176/ajp.138.8.1098
Gifford, 1970, Cushing's disease as a psychosomatic disorder: a selective review of the clinical and experimental literature and a report of ten cases, Perspect. Biol. Med., 169, 10.1353/pbm.1970.0019
Girdler, 2001, Allo-pregnanolone levels and mental stress in premenstrual dysphoric disorder, Biol. Psychiatry, 49, 788, 10.1016/S0006-3223(00)01044-1
Gold, 2002, Organization of the stress system and its dysregulation in melancholic and atypical depression: high vs low CRH/NE states, Mol. Psychiatry, 7, 254, 10.1038/sj.mp.4001032
Gold, 1988, Clinical and biochemical manifestations of depression: relation to the neurobiology of stress, N. Engl. J. Med., 319, 348, 10.1056/NEJM198808113190606
Gold, 1980, GABA levels in CSF of patients with psychiatric disorders, Am. J. Psychiatry, 137, 362, 10.1176/ajp.137.3.362
Gold, 2002, New insights into the role of cortisol and glucocorticoid receptor in severe depression, Biol. Psychiatry, 52, 381, 10.1016/S0006-3223(02)01480-4
Goodyer, 1996, Adrenal secretion during major depression in 8- to 16- years old: I. Altered diurnal rhythms in salivary cortisol and dehydroepiandrosterone (DHEA) at presentation, Psychol. Med., 26, 245, 10.1017/S0033291700034644
Gould, 2002
Grazzini, 1998, Inhibition of oxytocin receptors function by direct binding of progesterone, Nature, 392, 509, 10.1038/33176
Greener, 2003, Steroid actions get a rewrite, Scientist, 17, 32
Griffith, 1999, Selective serotonin reuptake inhibitors directly alter activity of neurosteroidogenic enzymes, Proc. Natl. Acad. Sci. U. S. A., 96, 13512, 10.1073/pnas.96.23.13512
Grobin, 1992, Regulation of the prefrontal cortical system by the neuroactive steroid 3,21 dihydro-5 α pregnane 20-on, Brain Res., 578, 351, 10.1016/0006-8993(92)90270-J
Guidotti, 1998, Can the antidysphoric and anxiolytic profiles of selective serotonin reuptake inhibitors be related to their ability to increase 3 alpha 5 alpha-tetrahydroprogesterone (allopregnanolone) availability?, Biol. Psychiatry, 44, 865, 10.1016/S0006-3223(98)00070-5
Gulinello, 2001, Short-term exposure to a neuroactive steroid increases alpha4 GABA(A) receptor subunit levels in association with increased anxiety in the female rat, Brain Res., 910, 55, 10.1016/S0006-8993(01)02565-3
Gulinello, 2002, Progesterone withdrawal increases the alpha 4 subunit of the GABA(A) receptor in male rats in association with anxiety and altered pharmacology—a comparison with female rats, Neuropharmacology, 43, 701, 10.1016/S0028-3908(02)00171-5
Harlan Meyer, 1994, Dehydroepiandrosterone sulfate alters synaptic potentials in area CA1 of the hippocampal slice, Brain, 633, 253, 10.1016/0006-8993(94)91546-6
Harrison, 1984, Modulation of the GABA receptor complex by a steroid anaesthetic, Brain Res., 323, 287, 10.1016/0006-8993(84)90299-3
Harrison, 1988, Rapid actions of steroids on CNS neurons, 137
Harris, 2001, Depression as a spreading adjustment disorder of monoaminergic neurons: a case for primary implications of the locus coeruleus, Brain Res. Rev., 38, 79, 10.1016/S0165-0173(01)00082-0
Hatzinger, 2000, Neuropeptides and the hypothalamic–pituitary–adrenocortical (HPA) system: review of recent research strategies in depression, World J. Biol. Psychiatry, 1, 105, 10.3109/15622970009150573
Hatzinger, 2000, Endogenous vasopressin contributed to hypothalamic–pituitary–adrenocortical alterations in aged rats, J. Endocrinol., 164, 197, 10.1677/joe.0.1640197
Hechter, 1997, Relationship of dehydroepiandrosterone and cortisol in disease, Med. Hypotheses, 49, 85, 10.1016/S0306-9877(97)90258-9
Hellsten, 2002, Electroconvulsive seizures increase hippocampal neurogenesis after chronic corticosterone treatment, Eur. J. Neurosci., 16, 283, 10.1046/j.1460-9568.2002.02093.x
Hellsten, 2004, Electroconvulsive seizures induce endothelial cell proliferation in adult rat hippocampus, Biol. Psychiatry, 55, 420, 10.1016/j.biopsych.2003.08.013
Heuser, 1987, Induction of anesthesia, seizures and sleep by steroid hormones, Anesthesiology, 28, 173, 10.1097/00000542-196701000-00018
Heydari, 2002, Low pregnenolone sulfate plasma concentrations in patients with generalized social phobia, Psychol. Med., 32, 929, 10.1017/S0033291702005238
Hobson, 1989, Sleep, 213
Holsboer, 2000, The corticosteroid receptor hypothesis of depression, Neuropsychopharmacology, 23, 477, 10.1016/S0893-133X(00)00159-7
Holsboer, 2000, Stress, hypercortisolism and corticosteroid receptors in depression: implications for therapy, J. Affect. Disord., 62, 77, 10.1016/S0165-0327(00)00352-9
Holzbauer, 1976, Physiological aspects of steroids with anaesthetic properties, Med. Biol., 54, 227
Holzbauer, 1985, In vivo secretion of 3 alpha hydroxy-5 pregnane 20-one, a potent anaesthetic steroid by the adrenal gland of the rat, J. Steroid Biochem., 22, 97, 10.1016/0022-4731(85)90147-5
Hubert, 1993, Film-induced amusement changes in saliva cortisol levels, Psychoneuroendocrinology, 18, 265, 10.1016/0306-4530(93)90023-E
Huppert, F.A., Van Niekerk, J.K., 2001. Dehydroepiandrosterone (DHEA) supplementation for cognitive function (Cochrane Review). The Cochrane Library, Issue 2. Update Software, Oxford.
Irwin, 1992, Pregnenolone sulfate augments NMDA receptor mediated increases in intracellular Ca2+ in cultured rat hippocampal neurons, Neurosci. Lett., 141, 30, 10.1016/0304-3940(92)90327-4
Irwin, 1994, Steroid potentiation and inhibition of N-methyl-d-aspartate receptor-mediated intracellular Ca++ responses: structure activity studies, J. Pharmacol. Exp. Ther., 271, 677
Jeffcoate, 1979, Psychiatric manifestations of Cushing's syndrome response to lowering of plasma cortisol, Q. J. Med., 4, 465
Joels, 2001, Corticosteroid actions in the hippocampus, J. Neuroendocrinol., 13, 657, 10.1046/j.1365-2826.2001.00688.x
Johansson, 2002, Allopregnanolone inhibits learning in the Morris water maze, Brain Res., 934, 125, 10.1016/S0006-8993(02)02414-9
Johnston, 1995, 285
Jones, 1994, Androgenic enhancement of motor neuron regeneration, Ann. N.Y. Acad. Sci., 141, 10.1111/j.1749-6632.1994.tb55791.x
Kalami, 1994, Anti-glucocorticoid effects of dehydroepiandrosterone (DHEA), Mol. Cell. Biochem., 131, 99, 10.1007/BF00925945
Kaminska, 1997, Dehydroepiandrosterone sulfate (DHEAS) counteracts the decremental effects of corticosterone on dentate gyrus LTP, Abstr.-Soc. Neurosci., 23, 418
Kaminska, 2000, Dehydroepiandrosterone sulfate (DHEAS) counteracts decremental effects of corticosterone on dentate gyrus LTP. Implication for depression, Brain Res. Bull., 52, 229, 10.1016/S0361-9230(00)00251-3
Kandel, 2000
Kavaliers, 1988, Inhibitory influences of the adrenal steroid 3α,5-α-tetrahydroxy-corticosterone on aggression and defeat-induced analgesia in mice, Psychopharmacology, 95, 488, 10.1007/BF00172960
Kelly, 1983, Cushing's syndrome and depression: a prospective study of 26 patients, Br. J. Psychiatry, 142, 16, 10.1192/bjp.142.1.16
Kerr, 1992, Hippocampal glucocorticoid receptor activation enhances voltage dependent Ca++ conductances: relevance to brain aging, Proc. Natl. Acad. Sci. U. S. A., 89, 8527, 10.1073/pnas.89.18.8527
Khisti, 2000, Serotonergic agents modulate antidepressant-like effects of the neurosteroid 3alpha-hydroxy-5alpha-pregnan-20-one in mice, Brain Res., 865, 291, 10.1016/S0006-8993(00)02373-8
Khisti, 2000, Antidepressant-like effect of the neurosteroid 3alpha-hydroxy-5alpha-pregnan-20-one in mice forced swim test, Pharmacol. Biochem. Behav., 67, 137, 10.1016/S0091-3057(00)00300-2
Khisti, 2002, GABAergic neurosteroid modulation of ethanol actions, World J. Biol. Psychiatry, 3, 87, 10.3109/15622970209150606
Khisti, 2002, The neurosteroid 3 alpha-hydroxy-5-alpha-pregnane-20-one affects dopamine-mediated behavior in rodents, Psychopharmacology, 161, 120, 10.1007/s00213-002-1006-5
Khisti, 2003, Neuroactive steroid 3a-hydroxy-5a-pregnan-20-one modulates ethanol-induced loss of righting reflex in rats, Brain Res., 980, 255, 10.1016/S0006-8993(03)02978-0
Khisti, 2003, Ethanol rapidly induces steroidogenic acute regulatory protein expression and translocation in rat adrenal gland, Eur. J. Pharmacol., 473, 225, 10.1016/S0014-2999(03)01969-1
Kim, 2002, The stressed hippocampus, synaptic plasticity and lost memories, Nat. Rev., Neurosci., 3, 453, 10.1038/nrn849
Kimonides, 1999, Dehydroepiandrosterone (DHEA) antagonises the neurotoxic effects of corticosterone, translocation of SAPK 3 in hippocampal primary cultures, Neuroscience, 89, 429, 10.1016/S0306-4522(98)00347-9
Kinouchi, 1989, Effects of d- and l-pentazocine on the release and uptake of norepinephrine in rat brain cortex, Res. Commun. Chem. Pathol. Pharmacol., 63, 201
Koksma, 2003, Oxytocin regulates neurosteroid modulation of GABAA receptors in supraoptic nucleus around parturition, J. Neurosci., 23, 788, 10.1523/JNEUROSCI.23-03-00788.2003
Kopin, 1995, Definitions of stress and sympathetic neuronal responses, Ann. N.Y. Acad. Sci., 771, 19, 10.1111/j.1749-6632.1995.tb44667.x
Kramlinger, 1981, Metyrapone for depression and delirium secondary to Cushing's syndrome, Psychosomatics, 26, 67, 10.1016/S0033-3182(85)72906-4
Kraulis, 1975, Distribution, metabolism and biological activity of deoxycorticosterone in the central nervous system, Brain Res., 88, 1, 10.1016/0006-8993(75)90942-7
Krieger, 1978, The central nervous system and Cushing's disease, Med. Clin. North Am., 62, 264, 10.1016/S0025-7125(16)31803-X
Kupfer, 1973, Sleep continuity changes in depression, Dis. Nerv. Syst., 34, 192
Ladurelle, 2000, Prolonged intracerebroventricular infusion of neurosteroids affects cognitive performances in the mouse, Brain Res., 858, 371, 10.1016/S0006-8993(00)01953-3
Lancel, 1997, Allopregnanolone affects sleep in a benzodiazepine-like fashion, J. Pharmacol. Exp. Ther., 282, 1213
Landgren, 1987, The effect of progesterone and its metabolites on the interictal epileptiform discharge in the cat's cerebral cortex, Acta Physiol. Scand., 131, 33, 10.1111/j.1748-1716.1987.tb08202.x
Langosch, 2002, Effects of the atypical antidepressant trimipramine on neuronal excitability and long-term potentiation in guinea pig hippocampal slices, Prog. Neuro-psychopharmacol. Biol. Psychiatry, 26, 299, 10.1016/S0278-5846(01)00269-X
Lapchak, 2001, Preclinical development of neurosteroids as neuro-protective agents for the treatment of neurodegenerative diseases, Int. Rev. Neurobiol., 46, 379, 10.1016/S0074-7742(01)46069-7
Leb, 1997, Metabolism of progesterone by human lymphocytes: production of neuroactive steroids, J. Clin. Endocrinol. Metab., 82, 4064, 10.1210/jc.82.12.4064
LeDoux, 2002
Le Foll, 1998, Pregnane steroid modulation of GABAA receptor in frog pituitary melanotrophs, Ann. N.Y. Acad. Sci., 839, 235, 10.1111/j.1749-6632.1998.tb10766.x
Le Melledo, 2002, Neuroactive steroids and anxiety disorders, J. Psychiatry Neurosci., 27, 161
Lephart, 1987, Effect of burn trauma on adrenal and testicular steroid hormone production, J. Clin. Endocrinol. Metab., 64, 842, 10.1210/jcem-64-4-842
Le Roith, 1980, Evolutionary origin of vertebrate hormones; substances similar to mammalian insulin are native to unicellular eukaryotes, Proc. Natl. Acad. Sci. U. S. A., 77, 6184, 10.1073/pnas.77.10.6184
Levine, 1983, A psychobiological approach to the study of coping, 107
Lewontin, 2000
Linkowsky, 1987, 24-hour profile of adrenocorticotropin, cortisol and growth hormone in major depressive illness: effect of antidepressant treatment, J. Clin. Endocrinol. Metab., 65, 141, 10.1210/jcem-65-1-141
Lishman, 1972, Selective factors in memory: Part 2. Affective disorder, Psychol. Med., 2, 248, 10.1017/S0033291700042549
Lishman, 1974, The speed of recall of pleasant and unpleasant experiences, Psychol. Med., 4, 212, 10.1017/S0033291700042045
Lloyd, 1975, Effect of depression on the speed of recall of pleasant and unpleasant experiences, Psychol. Med., 5, 173, 10.1017/S0033291700056440
Lupien, 1999, Working memory is more sensitive than declarative memory to the acute effects of corticosteroids: a dose–response study in humans, Behav. Neurosci., 113, 420, 10.1037/0735-7044.113.3.420
Lupien, 2002, The modulatory effects of corticosteroids on cognition: studies in young human populations, Psychoneuroendocrinology, 27, 401, 10.1016/S0306-4530(01)00061-0
Maclean, 1993, On the evolution of three mentalities
Maes, 1995, The serotonin hypothesis of major depression, 933
Magnaghi, 2001, Neuroactive steroids and peripheral myelin proteins, Brain Res. Rev., 37, 360, 10.1016/S0165-0173(01)00140-0
Majewska, 1992, Neurosteroids: endogenous bimodal modulators of the GABAA receptor. Mechanism of action and physiological significance, Prog. Neurobiol., 38, 379, 10.1016/0301-0082(92)90025-A
Majewska, 1990, The neurosteroid dehydroepiandrosterone sulfate is an allosteric antagonist of the GABAA receptor, Brain Res., 526, 143, 10.1016/0006-8993(90)90261-9
Mahlberg, 2004, Implications of adult hippocampal neurogenesis in antidepressant action, Rev. Psychiatry Neurosci., 29, 196
Malik, 2003, A novel dehydroepiandrosterone analog improves functional recovery in a rat traumatic brain injury model, J. Neurotrauma, 20, 463, 10.1089/089771503765355531
Manji, 2003, Enhancing neuronal plasticity and cellular resilience to develop novel, improved therapeutics for difficult-to-treat depression, Biol. Psychiatry, 53, 707, 10.1016/S0006-3223(03)00117-3
Markowitz, 1999, Possible dehydroepiandrosterone induced mania, Biol. Psychiatry, 45, 241, 10.1016/S0006-3223(98)00091-2
Martire, 1989, Different regulation of serotonin receptors following adrenal hormone imbalance in the rat hippocampus and hypothalamus, J. Neural Transm., 78, 109, 10.1007/BF01252497
Marx, 2000, Olanzapine increases allopregnanolone in the rat cerebral cortex, Biol. Psychiatry, 47, 1000, 10.1016/S0006-3223(99)00305-4
Marx, 2003, Olanzapine and clozapine increase the GABergic neuroactive steroid allopregnanelone in rodents, Neuropsychopharmacology, 28, 1, 10.1038/sj.npp.1300015
Mason, 1968, “Over-all” hormonal balance as a key to endocrine organization, Psychosom. Med., 30, 791, 10.1097/00006842-196809000-00033
Mason, 1971, A reevaluation of the concept of non-specificity in stress theory, J. Psychiatr. Res., 8, 323, 10.1016/0022-3956(71)90028-8
Mason, 1974, Specificity in the organization of neuroendocrine response profiles, 68
Massicotte, 1993, Chronic effects of trimipramine, an antidepressant, on hippocampal synaptic plasticity, Behav. Neural Biol., 59, 100, 10.1016/0163-1047(93)90808-U
Matsumoto, 1999, Permissive role of brain allopregnanolone content in the regulation of pentobarbital-inducing righting reflex loss, Neuropharmacology, 38, 955, 10.1016/S0028-3908(99)00018-0
Mayo, 1993, Infusion of neurosteroids into the nucleus basalis magnocellularis affects cognitive processes in the rat, Brain Res., 607, 324, 10.1016/0006-8993(93)91524-V
McEwen, 1999, Protective and damaging effects of mediators of stress: elaborating and testing the concepts of allostasis and allostatic load, Ann. N.Y. Acad. Sci., 896, 30, 10.1111/j.1749-6632.1999.tb08103.x
McGaugh, 2003
Medawar, 1953, Some immunogogical and endocrinological problems raised by the evolution of viviparity in vertebrates, 320
Meikle, 1992, The presence of a dehydroepiandrosterone-specific receptor binding complex in murine T cells, J. Steroid Biochem. Mol. Biol., 42, 293, 10.1016/0960-0760(92)90132-3
Melchior, 1994, Dehydroepiandrosterone is an anxiolytic in mice on the plus maze, Pharmacol. Biochem. Behav., 47, 437, 10.1016/0091-3057(94)90140-6
Mellon, 2002, Neurosteroids: biochemistry and clinical significance, Trends Endocrinol. Metab., 13, 35, 10.1016/S1043-2760(01)00503-3
Mendelson, 1987, Sleep induction by an adrenal steroid in the rat, Psychopharmacology, 93, 226, 10.1007/BF00179939
Mensah-Nyagen, 1999, Neurosteroids: expression of steroidogenic enzymes and regulation of steroid biosynthesis in the central nervous system, Pharmacol. Rev., 51, 63
Michael, 2000, Altered salivary dehydroepiandrosteron levels in major depression in adults, Biol. Psychiatry, 48, 989, 10.1016/S0006-3223(00)00955-0
Milner, 1972, Disorders of learning and memory after temporal lobe lesions in man, Clin. Neurosurg., 19, 421, 10.1093/neurosurgery/19.CN_suppl_1.421
Mitchell, 1984, Do corticosteroids really alter mood?, Postgrad. Med. J., 60, 467, 10.1136/pgmj.60.705.467
Mobley, 1980, Adrenal corticoids regulate sensitivity to noradrenaline receptor-coupled adenylate cyclase in brain, Nature, 286, 608, 10.1038/286608a0
Monnet, 1995, Neurosteroids, via sigma receptors, modulate the [3H] norepinephrine released evoked by N-methyl-d-aspartate in the rat hippocampus, Proc. Natl. Acad. Sci. U. S. A., 92, 3774, 10.1073/pnas.92.9.3774
Moran, 1998, Progesterone withdrawal: II. Insensitivity to the sedative effects of a benzodiazepine, Brain Res., 807, 91, 10.1016/S0006-8993(98)00781-1
Morrison, 2001, DHEA-S levels and depressive symptoms in a cohort of African American and Caucasian women in the late reproductive years, Biol. Psychiatry, 50, 705, 10.1016/S0006-3223(01)01169-6
Morrow, 1990, Characterization of steroid interactions with gamma-aminobutyric acid receptor-gated chloride ion channels: evidence for multiple steroid recognition sites, Mol. Pharmacol., 37, 263
Morrow, 1995, Neuroactive steroid modulators of the stress response, Ann. N.Y. Acad. Sci., 771, 257, 10.1111/j.1749-6632.1995.tb44687.x
Morrow, 2001, Ethanol and neurosteroid interactions in the brain, vol. 46
Muller-Preuss, 2002, The effects of the neuroactive steroid 3 alpha,5alpha-THDOC on sleep in the rat, Neuroreport, 13, 487, 10.1097/00001756-200203250-00026
Murialdo, 2001, Relationships between cortisol, dehydroepiandrostrone sulphate and insulin-like growth factor-1 system in dementia, J. Endocrinol. Invest., 24, 139, 10.1007/BF03343833
Murphy, 1999, Lack of specificity of urinary free cortisol determinations: why does it continue?, J. Clin. Endocrinol. Metab., 84, 2258, 10.1210/jc.84.6.2258-a
Murphy, 2003, Neuroactive steroid levels in patients with panic disorder, Am. J. Psychiatry, 160, 593, 10.1176/appi.ajp.160.3.593
Murphy, 2000, Determination of progesterone and some of its ring A-reduced metabolites in human serum, J. Steroid Biochem. Mol. Biol., 74, 137, 10.1016/S0960-0760(00)00098-4
Murphy, 2001, Neuroactive ring A-reduced metabolites of progestrone in human plasma during pregnancy: elevated levels of 5α-dihydroprogesterone in depressed patients during the latter half of pregnancy, J. Clin. Endocrinol. Metab., 86, 5981, 10.1210/jc.86.12.5981
Murphy, 2004, Elevated levels of some neuroactive progesterone metabolites, particularly isopregnanolone, in women with chronic fatigue syndrome, Psychoneuroendocrinology, 29, 245, 10.1016/S0306-4530(03)00026-X
Nadjafi-Triebsch, 2003, Progesteroneincrease under DHEA-substitution in males, Maturitas, 45, 231, 10.1016/S0378-5122(03)00147-6
Orentreich, 1984, Age changes and sex differences in serum dehydroepiandrosterone sulfate concentrations throughout adulthood, J. Clin. Endocrinol. Metab., 59, 551, 10.1210/jcem-59-3-551
Orentreich, 1992, Long-term longitudinal measurements of plasma dehydroepiandrosterone sulfate in normal men, J. Clin. Endocrinol. Metab., 75, 1002, 10.1210/jc.75.4.1002
Osran, 1993, Adrenal androgens and cortisol in major depression, Am. J. Psychiatry, 150, 806, 10.1176/ajp.150.5.806
Owens, 1992, 5α-pregnane-3α,21-diol-20-one (ATHDOC) attenuates mild stress-induced increases in plasma corticosterone via a non-glucocorticoid mechanism: comparison with alprazolam, Brain Res., 573, 353, 10.1016/0006-8993(92)90788-B
Padberg, 2002, Plasma concentrations of neuroactive steroids before and after repetitive transcranial magnetic stimulation (rTMS) in depression, Neuropsychopharmacology, 27, 874, 10.1016/S0893-133X(02)00355-X
Pakák, 2001, Stressor specificity of central neuroendocrine responses: implications for stress related disorders, Endocr. Rev., 22, 425
Papez, 1937, A proposed mechanism of emotion, Arch. Neurol. Psych., 38, 725, 10.1001/archneurpsyc.1937.02260220069003
Park-Chung, 1999, Sulfated and unsulfated steroids modulate gamma-aminobutyric acid. A receptor function through distinct sites, Brain Res., 830, 72, 10.1016/S0006-8993(99)01381-5
Pasini, 1996, The anticonvulsant action of fluoxetine in substantia nigra is dependent upon endogenous serotonin, Brain Res., 724, 84, 10.1016/0006-8993(96)00291-0
Patchev, 1994, The neurosteroid tetra-hydroprogesterone counteracts corticotropin-releasing hormone-induced anxiety and alters the release and gene expression of corticotropin-releasing hormone in the rat hypothalamus, Neuroscience, 62, 265, 10.1016/0306-4522(94)90330-1
Patchev, 1996, The neurosteroid tetraphydroprogesterone attenuates the endocrine response to stress and exerts glucocorticoid-like effects on vasopressin gene transcription in the rat hypothalamus, Neuropsychopharmacology, 15, 533, 10.1016/S0893-133X(96)00096-6
Patchev, 1997, Neonatal treatment of rats with the neuroactive steroid tetrahydrodeoxycorticosterone (THDOC) abolishes the behavioral and neuroendocrine consequences of adverse early life events, J. Clin. Invest., 99, 962, 10.1172/JCI119261
Pavlides, 1994, Type I adrenal steroid receptors prolong hippocampal long term potentiation, Neuroreport, 5, 2673, 10.1097/00001756-199412000-00067
Pavlides, 1995, Hippocampal homosynaptic long term depression/depotentiation induced by adrenal steroids, Neuroscience, 68, 379, 10.1016/0306-4522(95)94332-S
Picazo, 1995, Anti-anxiety effects of progesterone and some of its reduced metabolites: an evaluation using the burying behavior test, Brain Res., 680, 135, 10.1016/0006-8993(95)00254-N
Pisu, 2004, Neurosteroids and neuroactive drugs in mental disorders, Life Sci., 74, 3181, 10.1016/j.lfs.2003.12.002
Pope, 2000, Effects of supraphysiological doses of testosterone on mood and aggression in normal men, Arch. Gen. Psychiatry, 57, 133, 10.1001/archpsyc.57.2.133
Porsolt, 1978, Depression: a new animal model sensitive to antidepressant treatment, Nature, 266, 730, 10.1038/266730a0
Post, 1995, Stress conditioning and the temporal aspects of affective disorders, Ann. N.Y. Acad. Sci., 771, 677, 10.1111/j.1749-6632.1995.tb44720.x
Prasad, 1997, Dehydroepiandrosterone decreases behavioral despair in high- but not low- anxiety rats, Physiol. Behav., 58, 1053, 10.1016/S0031-9384(97)00239-4
Price, 1996, Antiglucocorticoids as treatments for depression. Rationale use and therapeutic potentials, CNS Drugs, 5, 311, 10.2165/00023210-199605050-00001
Prince, 1992, Steroid modulation of the strychnine-sensitive glycine receptor, Neuropharmacology, 31, 201, 10.1016/0028-3908(92)90168-O
Puia, 1990, Neurosteroids act on recombinant human GABAA receptors, Neuron, 4, 759, 10.1016/0896-6273(90)90202-Q
Puia, 1993, Does neurosteroid modulatory efficacy depend on GABAA receptor subunit composition?, Recept. Channels, 1, 135
Purdy, 1991, Stress-induced elevations of gamma-aminobutyric acid type A receptor-active steroids in the rat brain, Proc. Natl. Acad. Sci. U. S. A., 88, 4553, 10.1073/pnas.88.10.4553
Purdy, 1999, Potentiation of GABAergic neurostransmission by steroids, 143
Ravaris, 1988, Effect of ketoconazole on a hypophysectomized, hypercortisolemic, psychotically depressed woman (letter), Arch. Gen. Psychiatry, 45, 966, 10.1001/archpsyc.1988.01800340094019
Reddy, 1997, Differential anxiolytic effects of neurosteroids in the mirrored chamber behavior test in mice, Brain Res., 752, 61, 10.1016/S0006-8993(96)01447-3
Reddy, 2002, Stress-induced deoxycorticosterone-derived modulate GABA (A) receptor function and seizure susceptibility, J. Neurosci., 22, 3795, 10.1523/JNEUROSCI.22-09-03795.2002
Reddy, 1998, Sigma (sigma 1) receptor mediated anti-depressant-like effects of neurosteroids in the Porsolt forced swim test, Neuroreport, 9, 3069, 10.1097/00001756-199809140-00028
Reid, 2001, How antidepressant works: new perspectives on the pathophydiology of depressive disorder, Br. J. Psychiatry, 178, 299, 10.1192/bjp.178.4.299
Roberts, 1986, Guides through the labyrinth of AD: dehydroepiandosterone, potassium channels and the C4 component of complement, 173
Rodgers, 1998, Behaviorally selective effects of neuroactive steroids on plus-maze anxiety in mice, Pharmacol. Biochem. Behav., 59, 221, 10.1016/S0091-3057(97)00339-0
Romeo, 1998, Effects of antidepressant treatment on neuroactive steroids in major depression, Am. J. Psychiatry, 155, 910, 10.1176/ajp.155.7.910
Roozendal, 2002, Stress and memory: opposing effects of glucocorticoids on memory consolidation and memory retrieval, Neurobiol. Learn. Mem., 78, 578, 10.1006/nlme.2002.4080
Roth, 1982, The evolutionary origins of hormones, neurotransmitters and other extracellular chemical messengers. Implications for mammalian biology, N. Engl. J. Med., 306, 523, 10.1056/NEJM198203043060907
Rouge-Pont, 2002, The neurosteroid allopregnanolone increases dopamine release and dopaminergic response to morphine in the rat nucleus accumbens, Eur. J. Neurosci., 16, 169, 10.1046/j.1460-9568.2002.02084.x
Rupprecht, 1997, The neuropsychopharmacological potential of neuroactive steroids, J. Psychiatr. Res., 31, 297, 10.1016/S0022-3956(96)00060-X
Rupprecht, 2003, Neuroactive steroids: mechanisms of action and neuropsychopharmacological properties, Psychoneuroendocrinology, 28, 139, 10.1016/S0306-4530(02)00064-1
Rupprecht, 1993, Progesterone receptor-mediated effects of neuroactive steroids, Neuron, 11, 523, 10.1016/0896-6273(93)90156-L
Salek, 2002, The influence of hormones and pharmaceutical agents on DHEA and DHEA-S concentrations: a review of clinical studies, J. Clin. Pharmacol., 42, 247, 10.1177/00912700222011274
Sanacora, 2003, Increased cortical GABA concentrations in depressed patients receiving ECT, Am. J. Psychiatry, 160, 577, 10.1176/appi.ajp.160.3.577
Santarelli, 2003, Requirement of hippocampal neurogenesis for the behavioral effects of antidepressants, Science, 301, 805, 10.1126/science.1083328
Schacter, 1996
Schacter, 2001
Scharfman, 1985, Postsynaptic firing during repetititive stimulation is required for long term potentiation in hippocampus, Brain Res., 331, 267, 10.1016/0006-8993(85)91552-5
Schmidt, 1998, Differential behavioral effects of gonadal steroids in women with and in those without premenstrual syndrome, N. Engl. J. Med., 338, 209, 10.1056/NEJM199801223380401
Schüle, 2003, Influence of sleep deprivation on neuroactive steroids in major depression, Neuropsychopharmacology, 28, 577, 10.1038/sj.npp.1300084
Schumacher, 2000, Steroid synthesis and metabolism in the nervous system: trophic and protective effects, J. Neurocytol., 29, 307, 10.1023/A:1007152904926
Schumacher, 2001, Progesterone synthesis and myelin formation in peripheral nerves, Brain Res. Rev., 37, 343, 10.1016/S0165-0173(01)00139-4
Schwartz, 2002, Effects of androstenedione on long term potentiation in the rat dentate gyrus. Relevance for affective and degenerative diseases, Brain Res. Bull., 58, 207, 10.1016/S0361-9230(02)00781-5
Scott, 1999, Differences in adrenal steroid profile in chronic fatigue syndrome, in depression and in health, J. Affect. Disord., 54, 129, 10.1016/S0165-0327(98)00169-4
Semeniuk, 2001, Neuroactive steroid plasma levels in patients with generalized anxiety disorder, J. Neuropsychiatry Clin. Neurosci., 13, 396, 10.1176/appi.neuropsych.13.3.396
Serra, 2000, Steroidogenesis in rat brain induced by short- and long-term administration of carbamazepine, Neuropharmacology, 39, 2448, 10.1016/S0028-3908(00)00086-1
Serra, 2001, Opposite effects of short- versus long-term administration of fluoxetine on the concentrations of neuroactive steroids in rat plasma and brain, Psychopharmacology (Berl.), 158, 48, 10.1007/s002130100853
Simoncini, 2003, Non-genomic actions of sex steroid hormones, Eur. J. Endocrinol., 148, 281, 10.1530/eje.0.1480281
Sloviter, 1989, Selective loss of hippocampal granule cells in the mature rat brain after adrenalectomy, Science, 243, 535, 10.1126/science.2911756
Smith, 2002, Withdrawal properties of a neuroactive steroid: implications for GABAA receptor gene regulation in the brain and anxiety behavior, Steroids, 67, 519, 10.1016/S0039-128X(01)00170-2
Smith, 1998, GABAA receptor 4 subunit suppression prevents withdrawal properties of an endogenous steroid, Nature, 392, 926, 10.1038/31948
Spence, 1991, The neurosteroids pregnenolone and pregnenolone sulfate but not progesterone block Ca2+ currents in acutely isolated hippocampal CA1 neurons, Life Sci., 49, PL235, 10.1016/0024-3205(91)90649-V
Spivak, 2000, Elevated circulatory level of GABA(A)-antagonistic neurosteroids in patients with combat-related post-traumatic stress disorder, Psychol. Med., 30, 1227, 10.1017/S0033291799002731
Squire, 1999
Starkman, 1981, Depressed mood and other psychiatric manifestations of Cushing's syndrome relationship to hormone levels, Psychosom. Med., 43, 3, 10.1097/00006842-198102000-00002
Starkman, 1986, Cushing's syndrome after treatment. Changes in cortisol and ACTH levels and amelioration of the depressive syndrome, Psych. Res., 19, 177, 10.1016/0165-1781(86)90096-X
Stein, 2001, Brain damage, sex hormones and recovery: a new role for progesterone and estrogen?, Trends Neurosci., 24, 386, 10.1016/S0166-2236(00)01821-X
Steriade, 2001
Stewart, 2000, Repeated ECS and fluoxetine administration have equivalent effects on hippocampal synaptic plasticity, Psychopharmacology, 148, 217, 10.1007/s002130050045
Stoffel-Wagner, 2003, Neurosteroid biosynthesis in the human brain and its clinical implications, Ann. N.Y. Acad. Sci., 1007, 64, 10.1196/annals.1286.007
Stocco, 2000, The role of StAR protein in steroidogenesis: challenges for the future, J. Endocrinol., 164, 247, 10.1677/joe.0.1640247
Ströhle, 1999, Concentrations of 3 α reduced neuroactive steroids and their precursors in plasma of patients with major depression and after clinical recovery, Biol. Psychiatry, 45, 274, 10.1016/S0006-3223(98)00328-X
Ströhle, 2000, Fluoxetina decreases concentration of 3alpha 5 alpha tetra-hydrodeoxycorticosterone (THDOC) in major depression, J. Psychiatr. Res., 34, 183, 10.1016/S0022-3956(00)00006-6
Ströhle, 2002, GABAA receptor-modulating neuroactive steroid composition in patients with panic disorder before and during paroxetine treatment, Am. J. Psychiatry, 159, 145, 10.1176/appi.ajp.159.1.145
Ströhle, 2003, Induced panic attacks shift α-aminobutyric acid type A receptor modulatory neuroactive steroid composition in patients with panic disorder, Arch. Gen. Psychiatry, 60, 161, 10.1001/archpsyc.60.2.161
Strous, 2001, Analysis of neurosteroid levels in atention deficit hyperactivity disorder, Int. J. Neuropsychopharmacol., 4, 259, 10.1017/S1461145701002462
Strous, 2003, Dehydroepiandrostrone augmentation in the management of negative, depressive, and anxiety symptoms in schizophrenia, Arch. Gen. Psychiatry, 60, 133, 10.1001/archpsyc.60.2.133
Sundström, 1998, Patients with premenstrual syndrome have a different sensitivity to a neuroactive steroid during the menstrual cycle compared to control subjects, Neuroendocrinology, 67, 126, 10.1159/000054307
Tait, 2002, Neuroactive steroid changes in response to challenge with the panicogenic agent pentagastrin, Psychoneuroendocrinology, 27, 417, 10.1016/S0306-4530(01)00051-8
Teasdale, 1983, Affect and accessibility, Philos. Trans. R. Soc. Lond., B Biol. Sci., 302, 403, 10.1098/rstb.1983.0063
Teasdale, 1999, Functional MRI study of the cognitive generation of affect, Am. J. Psychiatry, 156, 209, 10.1176/ajp.156.2.209
The Lancet, 1986, Depression and Cushing's syndrome, Lancet, 1, 550
Thomas, 1994, Serum dehydroepiandrosterone sulfate levels as an individual marker, J. Clin. Endocrinol. Metab., 79, 1273, 10.1210/jc.79.5.1273
Tollefson, 1990, 24 hour urinary dehydroepiandrosterone sulfate in unipolar depression treated with cognitive and/or pharmacotherapy, Ann. Clin. Psychiatry, 2, 39, 10.3109/10401239009150005
Tottori, 2001, Antidepressant like responses to the combined sigma and 5-HT1A receptor agonist OPC-14523, Neuropharmacology, 41, 976, 10.1016/S0028-3908(01)00147-2
Turner, 1989, Modulation of the GABAA receptor complex by steroids in slices of rat cuneate nucleus, Br. J. Pharmacol., 96, 409, 10.1111/j.1476-5381.1989.tb11832.x
Ukai, 1998, Beneficial effects of acute and repeated administrations of sigma receptor agonists on behavioral despair in mice exposed to tail suspension, Pharmacol. Biochem. Behav., 61, 247, 10.1016/S0091-3057(98)00093-8
Urani, 1998, The modulation by neurosteroids of the scopolamine-induced learning impairment in mice involves an interaction with sigma 1 (sigma 1) receptors, Brain Res., 799, 64, 10.1016/S0006-8993(98)00469-7
Urani, 2001, The antidepressant-like effect induced by sigma (1)-receptor agonists and neuroactive steroids in mice submitted to the forced swimming test, J. Pharmacol. Exp. Ther., 298, 1269
Urbanoski, 2000, Effects of androsterone sulfate on the population spike of the rat dentate gyrus following tetanization, Physiol. Behav., 71, 435, 10.1016/S0031-9384(00)00354-1
Ursin, 1998, The psychology in psychoneuroendocrinology, Psychoneuroendocrinology, 23, 55, 10.1016/S0306-4530(98)00036-5
Uzunov, 1996, Fluoxetine-elicited changes in brain neurosteroid content measured by negative ion mass fragmentography, Proc. Natl. Acad. Sci. U. S. A., 93, 12599, 10.1073/pnas.93.22.12599
Uzunova, 1998, Increase in the cerebrospinal fluid content of neurosteroids in patients with unipolar major depression who are receiving fluoxetine or fluvoxamine, Proc. Natl. Acad. Sci. U. S. A., 95, 3239, 10.1073/pnas.95.6.3239
Uzunova, 2003, Region-specific dysregulation of allopregnanolone brain content in the olfactory bulbectomized rat model of depression, Brain Res., 976, 1, 10.1016/S0006-8993(03)02577-0
Uzunova, 2004, Chronic antidepressants reverse cerebrocortical allopregnanolone decline in the olfactory-bulbectomized rat, Eur. J. Pharmacol., 486, 31, 10.1016/j.ejphar.2003.12.002
Valera, 1992, Progesterone modulates a neuronal nicotonic acetylcholine receptor, Proc. Natl. Acad. Sci. U. S. A., 89, 49, 10.1073/pnas.89.20.9949
VanDoren, 2000, Neuroactive steroid 3α-hydroxy-5α-pregnan-20-one modulates electrophysiological and behavioral actions of ethanol, J. Neurosci., 20, 1982, 10.1523/JNEUROSCI.20-05-01982.2000
von Monakow, 1925
Wang, 1996, Relationship between symptom severity and steroid variation with women with premenstrual syndrome: study on serum pregnenolone, pregnenolone sulfate 5α-pregnan-3-20-dione and 3α-hydroxy-5 α-pregnan-20-one, Endocrinology, 81, 1076
Watanabe, 1993, Tricyclic antidepressant block NMDA receptor-mediated synaptic responses and induction of long-term potentiation in rat hippocampal slices, Neuropharmacology, 32, 479, 10.1016/0028-3908(93)90173-Z
Weaver, 1997, 17β-estradiol protects against NMDA-induced excitotoxicity by direct inhibition of NMDA receptors, Brain Res., 761, 338, 10.1016/S0006-8993(97)00449-6
Weaver, 1997, Neuroprotective activity of a new class of steroidal inhibitors of the N-methyl-d-aspartate receptor, Proc. Natl. Acad. Sci. U. S. A., 94, 10450, 10.1073/pnas.94.19.10450
Wehling, 1997, Specific, nongenomic actions of steroid hormones, Annu. Rev. Physiol., 59, 365, 10.1146/annurev.physiol.59.1.365
Weingartner, 1982, Models of cognitive impairment: cognitive changes in depression, Psychopharmacol. Bull., 18, 27
Wen, 2001, Treatment with dehydroepiandrosteron sulfate increases NMDA receptors in hippocampal and cortex, Eur. J. Pharmacol., 430, 373, 10.1016/S0014-2999(01)01383-8
Wieland, 1991, Anxiolytic activity of the progesterone metabolite 5 alpha-pregnan-3 alpha-ol-20-one, Brain Res., 565, 263, 10.1016/0006-8993(91)91658-N
Wilson, 1997, Influence of gender and brain region on neurosteroid modulation of GABA responses in rats, Life Sci., 60, 1679, 10.1016/S0024-3205(97)00110-0
Wolf, 1999, Actions of dehydroepiandrosterone and its sulfate in the central nervous sytem: effects on cognition and emotion in animals and humans, Res. Brain Res. Rev., 30, 264, 10.1016/S0165-0173(99)00021-1
Wolf, 1997, A single administration of dehydroepiandrosterone does not enhance memory performance in young healthy adults, but immediately reduces cortisol levels, Biol. Psychiatry, 42, 845, 10.1016/S0006-3223(97)00323-5
Wolf, 1998, Opposing effects of DHEA replacement in elderly subjects on declarative memory and attention after exposure to a laboratory stressor, Psychoneuroendocrinology, 23, 617, 10.1016/S0306-4530(98)00032-8
Wolf, 1998, Effects of dehydroepiandrosterone replacement in elderly men on event-related potentials, memory, and well-being, J. Gerontol., Ser. A, Biol. Sci. Med. Sci., 53, M385, 10.1093/gerona/53A.5.M385
Wolkowitz, 1999, Double blind treatment of major depression with dihydroepiandrosterone, Am. J. Psychiatry, 156, 646, 10.1176/ajp.156.4.646
Wu, 1991, Pregnenolone sulfate: a positive allosteric modulator at the N-methyl-d-aspartate receptor, Mol. Pharmacol., 40, 333
Xu, 1997, Behavioral stress facilitates the induction of long term depression in the hippocampus, Nature, 387, 497, 10.1038/387497a0
Yates, 2000, Testosterone in psychiatry. Risks and benefits, Arch. Gen. Psychiatry, 57, 155, 10.1001/archpsyc.57.2.155
Yates, 1990, Illicit anabolic steroid use, Acta Psychiatr. Scand., 81, 548, 10.1111/j.1600-0447.1990.tb05496.x
Yoo, 1996, Dose response study of dehydroepiandrosterone sulfate on dentate gyrus in LTP, Exp. Neurol., 137, 151, 10.1006/exnr.1996.0015
Young, 2002, Neuroprotective effects of antidepressant and mood stabilizing drugs, J. Psychiatry Neurosci., 27, 8
Young, 1991, Suppressive effects of dehydroepiandrosterone and 3 beta-methyl-androst-5-en-17- one on attact towards lactating female intruders by castrated male rice: II. Brain neurosteroids, Biochem. Biophys. Res. Commun., 174, 892, 10.1016/0006-291X(91)91501-3
Zhu, 1997, Neurosteroid prolongs GABAA channel deactivation by altering kinetics of desensitized states, J. Neurosci., 17, 4022, 10.1523/JNEUROSCI.17-11-04022.1997
Zimmerberg, 1998, Prenatal experience and postnatal stress modulate the adult neurosteroid and catecholaminergic stress responses, Int. J. Dev. Neurosci., 16, 217, 10.1016/S0736-5748(98)00024-0