Stem cell pluripotency and transcription factor Oct4

Cell Research - Tập 12 Số 5-6 - Trang 321-329 - 2002
Guangjin Pan1, Zeng Yi CHANG1, Hans R. Schöler2, Duanqing Pei3,1
1Departments of Pharmacology and Biological Sciences & Biotechnology, Schools of Sciences and Medicine, Tsinghua University, Beijing, China
2Department of Animal Biology, Center for Animal Transgenesis and Germ Cell Research, School of Veterinary Medicine, University of Pennsylvania, New Bolton Center, Kennett Square, USA
3Department of Pharmacology, University of Minnesota, Minneapolis, USA.

Tóm tắt

Từ khóa


Tài liệu tham khảo

Mish FC . Webster's ninth new collegiate dictionary 1988: pp1246.

Mintz B, K Illmensee . Normal genetically mosaic mice produced from malignant teratocarcinoma cells. Proc Natl Acad Sci USA 1975; 72:3585–9.

Illmensee K, B Mintz . Totipotency and normal differentiation of single teratocarcinoma cells cloned by injection into blastocysts. Proc Natl Acad Sci USA 1976; 73:549–53.

Evans MJ, MH Kaufman . Establishment in culture of pluripotential cells from mouse embryos. Nature 1981; 292:154–6.

Capecchi MR . Altering the genome by homologous recombination. Science 1989; 244:1288–92.

Thomson .A, J Itskovitz-Eldor, SS Shapiro, MA Waknitz, JJ Swiergiel, VS Marshall, JM Jones . Embryonic stem cell lines derived from human blastocysts. Science 1998; 282:1145–7.

Scholer H . Octamania: the POU factors in murine development. Trends Genet. 1991; 7:323–9.

Scholer H, S Ruppert, N Suzuki, K Chowdhury, P Gruss . New type of POU domain in germ line-specific protein Oct4. Nature 1990; 344:435–9.

Pesce M, and H Scholer . Oct4: gatekeeper in the beginnings of mammalian development. Stem Cells 2001; 19:271–8.

Scholer H, G Dressler, R Balling, H Rohdewohld, P Gruss . Oct4: a germline-specific transcription factor mapping to the mouse t-complex. EMBO J 1990; 9:2185–95.

Pesce M, H Scholer . Oct4: control of totipotency and germline determination. Mol Rep Dev 2000; 55:452–7.

Nichols J, B Zevnik, K Anastassiadis, H Niwa, D Klewe-Nebenius, I Chambers, H Scholer, A Smith . Formation of pluripotent stem cells in the mammalian embryo depends on the POU transcription factor Oct4. Cell 1998; 95:379–91.

Niwa H . Molecular mechanism to maintain stem cell renewal of ES cells. Cell Str & Func 2001; 26:13748.

Niwa H, J Miyazaki, A Smith . Quantitative expression of Oct-3/4 defines differentiation, dedifferentiation or self-renewal of ES cells. Nat Genet 2000; 24:372–6.

Klemm JD, MA Rould, R Aurora, W Herr, CO Pabo . Crystal structure of the Oct-1 POU domain bound to an octamer site: DNA recognition with tethered DNA-binding modules. Cell 1994; 77:21–32.

Brehm A, K Ohbo, H Scholer . The carboxy-terminal transactivation domain of Oct4 acquires cell specificity through the POU domain. Mol Cell Biol 1997; 17:154–62.

Vigano MA, LM Staudt . Transcriptional activation by Oct-3: evidence for a specific role of the POU-specific domain in mediating functional interaction with Oct-1. Nucleic Acids Res 1996; 24:2112–8.

Brehm A, C Ovitt, H Scholer . Oct4: more than just a POUerful marker of the mammalian germline? Apmis 1998; 106:114–24.

Brehm A, K Ohbo, W Zwerschke, V Botquin, P Jansen-Durr, H Scholer . Synergism with germ line transcription factor Oct4: viral oncoproteins share the ability to mimic a stem cell-specific activity. Mol Cell Biol 1999; 19:263543.

Pesce M, X Wang, D Wolgemuth, H Scholer . Differential expression of the Oct4 transcription factor during mouse germ cell differentiation. Mech Dev 1998; 71:89–98.

Palmieri S, W Peter, H Hess, H Scholer . Oct4 transcription factor is differentially expressed in the mouse embryo during establishment of the first two extraembryonic cell lineages involved in implantation. Dev Biol 1994; 166:259–67.

Hansis C, J Grifo, L Krey . Oct4 expression in inner cell mass and trophectoderm of human blastocysts. Mol Hum Reprod 2000; 6:999–1004.

Hansis C, Y Tang, J Grifo, L Krey . Analysis of Oct4 expression and ploidy in individual human blastomeres. Mol Hum Reprod 2001; 7:155–61.

Ben-Shushan E, E Pikarsky, A Klar, Y Bergman . Extinction of Oct-3/4 gene expression in embryonal carcinoma x fibroblast somatic cell hybrids is accompanied by changes in the methylation status, chromatin structure, and transcriptional activity of the Oct-3/4 upstream region. Mol Cell Biol 1993; 13:891–901.

Yeom Y, G Fuhrmann, C Ovitt, A Brehm, K Ohbo, M Gross, K Hubner, H Scholer . Germline regulatory element of Oct4 specific for the totipotent cycle of embryonal cells. Integrated Ann Indexes 1996; 122:881–94.

Nordhoff V, K Hubner, A Bauer, I Orlova, A Malapetsa, H Scholer . Comparative analysis of human, bovine, and murine Oct4 upstream promoter sequences. Mamm Genome 2001; 12:309–17.

Hummelke GC, AJ Cooney . Germ cell nuclear factor is a transcriptional repressor essential for embryonic development. Front Biosci 2001; 6:D1186–91.

Fuhrmann G, AC Chung, KJ Jackson, G Hummelke, A Baniahmad, J Sutter, I Sylvester, HR Scholer, AJ Cooney . Mouse germline restriction of Oct4 expression by germ cell nuclear factor. Dev Cell 2001; 1:377–87.

Jaenisch R . DNA methylation and imprinting: why bother? Trends Genet 1997; 13:323–9.

Goto T, J Adjaye, C Rodeck, M Monk . Identification of genes expressed in human primordial germ cells at the time of entry of the female germ line into meiosis. Mol Hum Reprod 1999; 5:851–60.

Pesce M, M Gross, H Scholer . In line with our ancestors: Oct4 and the mammalian germ. Bioessays 1998; 20:722–32.

Liu L, R Roberts . Silencing of the gene for the beta subunit of human chorionic gonadotropin by the embryonic transcription factor Oct-3/4. J Biol Chem 1996; 271:16683–9.

Liu L, D Leaman, M Villalta, R Roberts . Silencing of the gene for the alpha-subunit of human chorionic gonadotropin by the embryonic transcription factor Oct-3/4. Mol Endocrinol 1997; 11:1651–8.

Hromas R, R Costa . The hepatocyte nuclear factor-3/forkhead transcription regulatory family in development, inflammation, and neoplasia. Crit Rev Oncol Hematol 1995; 20:12940.

Guo Y, R Costa, H Ramsey, T Starnes, G Vance, K Robertson, M Kelley, R Reinbold, H Scholer, R Hromas . The embryonic stem cell transcription factors Oct4 and FoxD3 interact to regulate endodermal-specific promoter expression. Proc Natl Acad Sci USA 2002; 99:3663–7.

Yamamoto H, ML Flannery, S Kupriyanov, J Pearce, SR McKercher, GW Henkel, RA Maki, Z Werb, RG Oshima . Defective trophoblast function in mice with a targeted mutation of Ets2. Genes Dev 1998; 12:1315–26.

Ezashi T, D Ghosh, RM Roberts . Repression of Ets-2-induced transactivation of the tau interferon promoter by Oct4. Mol Cell Biol 2001; 21:7883–91.

Butteroni C, FM De, H Scholer, M Pesce . Phage display screening reveals an association between germline-specific transcription factor Oct4 and multiple cellular proteins. J Mol Biol 2000; 304:52940.

Scholer H, T Ciesiolka, P Gruss . A nexus between Oct4 and E1A: implications for gene regulation in embryonic stem cells. Cell 1991; 66:291–304.

Curatola AM, C Basilico . Expression of the K-fgf proto-oncogene is controlled by 3' regulatory elements which are specific for embryonal carcinoma cells. Mol Cell Biol 1990; 10:2475–84.

Yuan H, N Corbi, C Basilico, L Dailey . Developmental-specific activity of the FGF4 enhancer requires the synergistic action of Sox-2 and Oct-3. Genes Dev 1995; 9:263545.

Ambrosetti DC, C Basilico, L Dailey . Synergistic activation of the fibroblast growth factor 4 enhancer by Sox2 and Oct-3 depends on protein-protein interactions facilitated by a specific spatial arrangement of factor binding sites. Mol Cell Biol 1997; 17:6321–9.

Ambrosetti DC, HR Scholer, L Dailey, C Basilico . Modulation of the activity of multiple transcriptional activation domains by the DNA binding domains mediates the synergistic action of Sox-2 and Oct-3 on the fibroblast growth factor4 enhancer. J Biol Chem 2000; 275:23387–97.

Tomioka M, M Nishimoto, S Miyagi, T Katayanagi, N Fukui, H Niwa, M Muramatsu, A Okuda . Identification of Sox-2 regulatory region which is under the control of Oct-3/4-Sox-2 complex. Nucleic Acids Res 2002; 30:3202–13.

Nishimoto M, A Fukushima, A Okuda, M Muramatsu . The gene for the embryonic stem cell coactivator UTF1 carries a regulatory element which selectively interacts with a complex composed of Oct-3/4 and Sox-2. Mol Cell Biol 1999; 19:5453–65.

Wakayama T, R Yanagimachi . Cloning the laboratory mouse. Semin Cell Dev Biol 1999; 10:253–8.

Wakayama T, H Tateno, P Mombaerts, R Yanagimachi . Nuclear transfer into mouse zygotes. Nat Genet 2000; 24:108–9.

Wakayama T, R Yanagimachi . Mouse cloning with nucleus donor cells of different age and type. Mol Reprod Dev 2001; 58:376–83.

Du Z, H Cong, Z Yao . Identification of putative downstream genes of Oct4 by suppression-subtractive hybridization. Biochem Biophys Res Comm 2001; 282:701–6.

Boiani M, S Eckardt, H Scholer, K McLaughlin . Oct4 distribution and level in mouse clones: consequences for pluripotency. Genes Dev 2002; 16:1209–19.

Palumbo C, RK van, A Gillis, GR van, MH de, J Oosterhuis, ZE van, L. Looijenga . Expression of the PDGF alpha-receptor 1.5 kb transcript, OCT4, and c-Kit in human normal and malignant tissues. Implications for the early diagnosis of testicular germ cell tumours and for our understanding of regulatory mechanisms. J Path 2002; 196:467–77.

Monk M, C Holding . Human embryonic genes re-expressed in cancer cells. Oncogene 2001; 20:8085–91.

Jin T, DR Branch, X Zhang, S Qi, B Youngson, PE Goss . Examination of POU homeobox gene expression in human breast cancer cells. Int J Cancer 1999; 81:104–12.