Statistical media optimization and alkaline protease production from Bacillus mojavensis in a bioreactor

Gupta R, Beg QK, Khan S, Chauhan B. An overview on fermentation, downstream processing and properties of microbial alkaline proteases, Appl Microbiol Biotechnol 2002;60:381–395.

Gupta, 2002, Bacterial alkaline proteases: molecular approaches and industrial applications, Appl. Microbiol. Biotechnol, 59, 15, 10.1007/s00253-002-0975-y

Beg, 2002, De-repression and subsequent induction of protease synthesis by Bacillus mojavensis under fed-batch operations, Process. Biochem., 37, 1103, 10.1016/S0032-9592(01)00320-X

Ferrero, 1996, Thermostable alkaline protease of Bacillus licheniformis MIR 29: isolation, production and characterization, Appl. Microbiol. Biotechnol., 45, 327, 10.1007/s002530050691

Kole, 1988, Production of protease by Bacillus subtilis using simultaneous control of glucose and ammonium concentrations, J. Chem. Technol. Biotechnol., 41, 197, 10.1002/jctb.280410305

Varela, 1996, Effect of medium composition on the production by a new Bacillus subtilis isolate of protease with promising unhairing activity, World J. Microbiol. Biotechnol., 12, 643, 10.1007/BF00327730

Hameed, 1999, Effect of dissolved oxygen tension and pH on the production of extracellular protease from a new isolate of Bacillus subtilis K2, for use in leather processing, J. Chem. Technol. Biotechnol., 74, 5, 10.1002/(SICI)1097-4660(199901)74:1<5::AID-JCTB979>3.0.CO;2-T

Nehete, 1985, Profiles of alkaline protease production as a function of composition of the slant, age, transfer and isolate number and physiological state of culture, Biotechnol. Lett., 7, 413, 10.1007/BF01166214

Haaland, 1989, Statistical problem solving, 1

Beg, 2002, Kinetic constants determination for an alkaline protease from Bacillus mojavensis using response surface methodology, Biotechnol. Bioeng., 78, 289, 10.1002/bit.10203

De Coninck, 2000, Industrial media and fermentation process for improved growth and protease production by Tetrahymena thermophila BIII, J. Ind. Microbiol. Biotechnol., 24, 285, 10.1038/sj.jim.2900826

Puri, 2002, Optimization of alkaline protease production from Bacillus sp. using response surface methodology, Curr. Microbiol., 44, 286, 10.1007/s00284-001-0006-8

Beg QK, Gupta R. Purification and characterization of an oxidation-stable, thiol-dependent serine alkaline protease from Bacillus mojavensis, Enzyme Microb Technol 2002;32:294–304.

Gupta, 1999, Bleach-stable, alkaline protease from Bacillus sp, Biotechnol. Lett., 21, 135, 10.1023/A:1005478117918

Miller, 1959, Use of dinitrosalicylic acid reagent for determination of reducing sugar, Anal. Chem., 31, 426, 10.1021/ac60147a030

Moon, 1991, A parametric study of protease production in batch and fed-batch cultures of Bacillus firmus, Biotechnol. Bioeng., 37, 467, 10.1002/bit.260370509

Chu, 1992, Production and degradation of alkaline protease in batch cultures of Bacillus subtilis ATCC 14416, Enzyme Microb. Technol., 14, 755, 10.1016/0141-0229(92)90116-6

Sen, 1993, Optimization of alkaline protease production by thermophilic Bacillus licheniformis S-40, Indian J. Microbiol., 33, 43

Fujiwara, 1987, Production of an alkaline protease in a low-cost medium by alkalophilic Bacillus sp. and properties of the enzyme, J. Ferment. Technol., 65, 345, 10.1016/0385-6380(87)90098-7

Jang, 2001, Enhanced thermal stability of an alkaline protease, AprP, isolated from a Pseudomonas sp. by mutation at an autoproteolysis site, Ser-331, Biotechnol. Appl. Biochem., 34, 81, 10.1042/BA20010027