Stage-dependent expression of PI3K/Akt-pathway genes in neuroblastoma
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Engelman, 2006, The evolution of phosphatidylinositol 3-kinases as regulators of growth and metabolism, Nat Rev Genet, 7, 606, 10.1038/nrg1879
Saal, 2007, Poor prognosis in carcinoma is associated with a gene expression signature of aberrant PTEN tumor suppressor pathway activity, Proc Natl Acad Sci USA, 104, 7564, 10.1073/pnas.0702507104
Tang, 2006, Phosphorylated Akt overexpression and loss of PTEN expression in non-small cell lung cancer confers poor prognosis, Lung Cancer, 51, 181, 10.1016/j.lungcan.2005.10.003
Aleskandarany, 2010, PIK3CA expression in invasive breast cancer: a biomarker of poor prognosis, Breast Cancer Res Treat, 122, 45, 10.1007/s10549-009-0508-9
Kato, 2007, PIK3CA mutation is predictive of poor survival in patients with colorectal cancer, Int J Cancer, 121, 1771, 10.1002/ijc.22890
Chapuis, 2010, Autocrine IGF-1/IGF-1R signaling is responsible for constitutive PI3K/Akt activation in acute myeloid leukemia: therapeutic value of neutralizing anti-IGF-1R antibody, Haematologica, 95, 415, 10.3324/haematol.2009.010785
Muders, 2009, Vascular endothelial growth factor-C protects prostate cancer cells from oxidative stress by the activation of mammalian target of rapamycin complex-2 and AKT-1, Cancer Res, 69, 6042, 10.1158/0008-5472.CAN-09-0552
Puri, 2008, Synergism of EGFR and c-Met pathways, cross-talk and inhibition, in non-small cell lung cancer, J Carcinog, 7, 9, 10.4103/1477-3163.44372
De Preter, 2006, Human fetal neuroblast and neuroblastoma transcriptome analysis confirms neuroblast origin and highlights neuroblastoma candidate genes, Genome Biol, 7, R84, 10.1186/gb-2006-7-9-r84
Dam, 2006, Mutations in PIK3CA are infrequent in neuroblastoma, BMC Cancer, 6, 177, 10.1186/1471-2407-6-177
Moritake, 2001, Analysis of PTEN/MMAC1 alteration in neuroblastoma, Cancer Genet Cytogenet, 125, 151, 10.1016/S0165-4608(00)00378-2
Caren, 2007, Genetic and epigenetic changes in the common 1p36 deletion in neuroblastoma tumours, Br J Cancer, 97, 1416, 10.1038/sj.bjc.6604032
Boller, 2008, Targeting the phosphoinositide 3-kinase isoform p110delta impairs growth and survival in neuroblastoma cells, Clin Cancer Res, 14, 1172, 10.1158/1078-0432.CCR-07-0737
Fransson, 2007, Neuroblastoma tumors with favorable and unfavorable outcomes: significant differences in mRNA expression of genes mapped at 1p36.2, Genes Chromosomes Cancer, 46, 45, 10.1002/gcc.20387
Johnsen, 2008, Inhibitors of mammalian target of rapamycin downregulate MYCN protein expression and inhibit neuroblastoma growth in vitro and in vivo, Oncogene, 27, 2910, 10.1038/sj.onc.1210938
Opel, 2007, Activation of Akt predicts poor outcome in neuroblastoma, Cancer Res, 67, 735, 10.1158/0008-5472.CAN-06-2201
Brodeur, 2009, Trk receptor expression and inhibition in neuroblastomas, Clin Cancer Res, 15, 3244, 10.1158/1078-0432.CCR-08-1815
Fredlund, 2008, High Myc pathway activity and low stage of neuronal differentiation associate with poor outcome in neuroblastoma, Proc Natl Acad Sci USA, 105, 14094, 10.1073/pnas.0804455105
Hedborg, 1995, Biochemical evidence for a mature phenotype in morphologically poorly differentiated neuroblastomas with a favourable outcome, Eur J Cancer, 31A, 435, 10.1016/0959-8049(95)00025-E
Brodeur, 2003, Neuroblastoma: biological insights into a clinical enigma, Nat Rev Cancer, 3, 203, 10.1038/nrc1014
Chesler, 2006, Inhibition of phosphatidylinositol 3-kinase destabilizes Mycn protein and blocks malignant progression in neuroblastoma, Cancer Res, 66, 8139, 10.1158/0008-5472.CAN-05-2769
Yamamoto, 1998, The roles of protein kinase C beta I and beta II in vascular smooth muscle cell proliferation, Exp Cell Res, 240, 349, 10.1006/excr.1998.3999
Borner, 1995, Two closely related isoforms of protein kinase C produce reciprocal effects on the growth of rat fibroblasts, Possible molecular mechanisms J Biol Chem, 270, 78
Zeidman, 1999, Novel and classical protein kinase C isoforms have different functions in proliferation, survival and differentiation of neuroblastoma cells, Int J Cancer, 81, 494, 10.1002/(SICI)1097-0215(19990505)81:3<494::AID-IJC26>3.0.CO;2-L
Svensson, 2000, Protein kinase C beta1 is implicated in the regulation of neuroblastoma cell growth and proliferation, Cell Growth Differ, 11, 641
Mak, 2001, Expression of protein kinase C isoforms in euxanthone-induced differentiation of neuroblastoma cells, Planta Med, 67, 400, 10.1055/s-2001-15809
Macfarlane, 1994, Activation of beta-isozyme of protein kinase C (PKC beta) is necessary and sufficient for phorbol ester-induced differentiation of HL-60 promyelocytes, Studies with PKC beta-defective PET mutant J Biol Chem, 269, 4327
Liu, 2001, Insulin stimulates PKCzeta-mediated phosphorylation of insulin receptor substrate-1 (IRS-1). A self-attenuated mechanism to negatively regulate the function of IRS proteins, J Biol Chem, 276, 14459, 10.1074/jbc.M007281200
Nazarenko, 2010, Atypical protein kinase C zeta exhibits a proapoptotic function in ovarian cancer, Mol Cancer Res, 8, 919, 10.1158/1541-7786.MCR-09-0358
Guo, 2009, Reduction of protein kinase C zeta inhibits migration and invasion of human glioblastoma cells, J Neurochem, 109, 203, 10.1111/j.1471-4159.2009.05946.x
Mei, 2012, Regulation of neuroblastoma differentiation by forkhead transcription factors FOXO1/3/4 through the receptor tyrosine kinase PDGFRA, Proc Natl Acad Sci USA, 109, 4898, 10.1073/pnas.1119535109
Pahlman, 1992, Platelet-derived growth factor potentiates phorbol ester-induced neuronal differentiation of human neuroblastoma cells, Cell Growth Differ, 3, 783
Yu, 2003, Platelet-derived growth factor signaling and human cancer, J Biochem Mol Biol, 36, 49
Barber, 2006, PTEN regulation, a novel function for the p85 subunit of phosphoinositide 3-kinase, Sci STKE, pe49
Rabinovsky, 2009, p85 associates with unphosphorylated PTEN and the PTEN-associated complex, Mol Cell Biol, 29, 5377, 10.1128/MCB.01649-08
Chagpar, 2010, Direct positive regulation of PTEN by the p85 subunit of phosphatidylinositol 3-kinase, Proc Natl Acad Sci USA, 107, 5471, 10.1073/pnas.0908899107
Taniguchi, 2010, The phosphoinositide 3-kinase regulatory subunit p85alpha can exert tumor suppressor properties through negative regulation of growth factor signaling, Cancer Res, 70, 5305, 10.1158/0008-5472.CAN-09-3399
Luo, 2005, The negative regulation of phosphoinositide 3-kinase signaling by p85 and it’s implication in cancer, Cell Cycle, 4, 1309, 10.4161/cc.4.10.2062
Yu, 1998, Regulation of the p85/p110 phosphatidylinositol 3’-kinase: stabilization and inhibition of the p110alpha catalytic subunit by the p85 regulatory subunit, Mol Cell Biol, 18, 1379, 10.1128/MCB.18.3.1379
Shekar, 2005, Mechanism of constitutive phosphoinositide 3-kinase activation by oncogenic mutants of the p85 regulatory subunit, J Biol Chem, 280, 27850, 10.1074/jbc.M506005200
Jimenez, 1998, Identification and characterization of a new oncogene derived from the regulatory subunit of phosphoinositide 3-kinase, EMBO J, 17, 743, 10.1093/emboj/17.3.743
Philp, 2001, The phosphatidylinositol 3’-kinase p85alpha gene is an oncogene in human ovarian and colon tumors, Cancer Res, 61, 7426
Lopez-Carballo, 2002, Activation of the phosphatidylinositol 3-kinase/Akt signaling pathway by retinoic acid is required for neural differentiation of SH-SY5Y human neuroblastoma cells, J Biol Chem, 277, 25297, 10.1074/jbc.M201869200
Evangelopoulos, 2005, Signalling pathways leading to neuroblastoma differentiation after serum withdrawal: HDL blocks neuroblastoma differentiation by inhibition of EGFR, Oncogene, 24, 3309, 10.1038/sj.onc.1208494
Evangelopoulos, 2009, Mevastatin-induced neurite outgrowth of neuroblastoma cells via activation of EGFR, J Neurosci Res, 87, 2138, 10.1002/jnr.22025
Wilzen, 2009, The Phox2 pathway is differentially expressed in neuroblastoma tumors, but no mutations were found in the candidate tumor suppressor gene PHOX2A, Int J Oncol, 34, 697