Stage-Specific Optimization of Activin/Nodal and BMP Signaling Promotes Cardiac Differentiation of Mouse and Human Pluripotent Stem Cell Lines
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Agius, 2000, Endodermal Nodal-related signals and mesoderm induction in Xenopus, Development, 127, 1173, 10.1242/dev.127.6.1173
Conlon, 1994, A primary requirement for nodal in the formation and maintenance of the primitive streak in the mouse, Development, 120, 1919, 10.1242/dev.120.7.1919
Davis, 2004, BMP receptor IA is required in the mammalian embryo for endodermal morphogenesis and ectodermal patterning, Dev. Biol., 270, 47, 10.1016/j.ydbio.2004.01.048
Ema, 2006, Deletion of the selection cassette, but not cis-acting elements, in targeted Flk1-lacZ allele reveals Flk1 expression in multipotent mesodermal progenitors, Blood, 107, 111, 10.1182/blood-2005-05-1970
Ferkowicz, 2003, CD41 expression defines the onset of primitive and definitive hematopoiesis in the murine embryo, Development, 130, 4393, 10.1242/dev.00632
Fujiwara, 2002, Distinct requirements for extra-embryonic and embryonic bone morphogenetic protein 4 in the formation of the node and primitive streak and coordination of left-right asymmetry in the mouse, Development, 129, 4685, 10.1242/dev.129.20.4685
Gadue, 2006, Wnt and TGF-beta signaling are required for the induction of an in vitro model of primitive streak formation using embryonic stem cells, Proc. Natl. Acad. Sci. USA, 103, 16806, 10.1073/pnas.0603916103
Gritsman, 2000, Nodal signaling patterns the organizer, Development, 127, 921, 10.1242/dev.127.5.921
Haegel, 1995, Lack of beta-catenin affects mouse development at gastrulation, Development, 121, 3529, 10.1242/dev.121.11.3529
Hao, 2008, Dorsomorphin, a selective small molecule inhibitor of BMP signaling, promotes cardiomyogenesis in embryonic stem cells, PLoS ONE, 3, e2904, 10.1371/journal.pone.0002904
Hirata, 2007, Coexpression of platelet-derived growth factor receptor alpha and fetal liver kinase 1 enhances cardiogenic potential in embryonic stem cell differentiation in vitro, J. Biosci. Bioeng., 103, 412, 10.1263/jbb.103.412
Hotta, 2009, Isolation of human iPS cells using EOS lentiviral vectors to select for pluripotency, Nat. Methods, 6, 370, 10.1038/nmeth.1325
Inman, 2002, SB-431542 is a potent and specific inhibitor of transforming growth factor-beta superfamily type I activin receptor-like kinase (ALK) receptors ALK4, ALK5, and ALK7, Mol. Pharmacol., 62, 65, 10.1124/mol.62.1.65
Johansson, 1995, Evidence for involvement of activin A and bone morphogenetic protein 4 in mammalian mesoderm and hematopoietic development, Mol. Cell. Biol., 15, 141, 10.1128/MCB.15.1.141
Kataoka, 1997, Expressions of PDGF receptor alpha, c-Kit and Flk1 genes clustering in mouse chromosome 5 define distinct subsets of nascent mesodermal cells, Dev. Growth Differ., 39, 729, 10.1046/j.1440-169X.1997.t01-5-00009.x
Kattman, 2006, Multipotent flk-1+ cardiovascular progenitor cells give rise to the cardiomyocyte, endothelial, and vascular smooth muscle lineages, Dev. Cell, 11, 723, 10.1016/j.devcel.2006.10.002
Kennedy, 2007, Development of the hemangioblast defines the onset of hematopoiesis in human ES cell differentiation cultures, Blood, 109, 2679, 10.1182/blood-2006-09-047704
Klaus, 2007, Distinct roles of Wnt/beta-catenin and Bmp signaling during early cardiogenesis, Proc. Natl. Acad. Sci. USA, 104, 18531, 10.1073/pnas.0703113104
Kouskoff, 2005, Sequential development of hematopoietic and cardiac mesoderm during embryonic stem cell differentiation, Proc. Natl. Acad. Sci. USA, 102, 13170, 10.1073/pnas.0501672102
Kubo, 2004, Development of definitive endoderm from embryonic stem cells in culture, Development, 131, 1651, 10.1242/dev.01044
Kuzmenkin, 2009, Functional characterization of cardiomyocytes derived from murine induced pluripotent stem cells in vitro, FASEB J., 23, 4168, 10.1096/fj.08-128546
Ladd, 1998, Regulation of avian cardiac myogenesis by activin/TGFbeta and bone morphogenetic proteins, Dev. Biol., 204, 407, 10.1006/dbio.1998.9094
Laflamme, 2007, Cardiomyocytes derived from human embryonic stem cells in pro-survival factors enhance function of infarcted rat hearts, Nat. Biotechnol., 25, 1015, 10.1038/nbt1327
Liu, 2007, Sox17 is essential for the specification of cardiac mesoderm in embryonic stem cells, Proc. Natl. Acad. Sci. USA, 104, 3859, 10.1073/pnas.0609100104
Lowe, 2001, Genetic dissection of nodal function in patterning the mouse embryo, Development, 128, 1831, 10.1242/dev.128.10.1831
Lu, 2004, Multiple roles for Nodal in the epiblast of the mouse embryo in the establishment of anterior-posterior patterning, Dev. Biol., 273, 149, 10.1016/j.ydbio.2004.06.004
Marvin, 2001, Inhibition of Wnt activity induces heart formation from posterior mesoderm, Genes Dev., 15, 316, 10.1101/gad.855501
Mauritz, 2008, Generation of functional murine cardiac myocytes from induced pluripotent stem cells, Circulation, 118, 507, 10.1161/CIRCULATIONAHA.108.778795
Mikkola, 2003, Expression of CD41 marks the initiation of definitive hematopoiesis in the mouse embryo, Blood, 101, 508, 10.1182/blood-2002-06-1699
Moretti, 2006, Multipotent embryonic isl1+ progenitor cells lead to cardiac, smooth muscle, and endothelial cell diversification, Cell, 127, 1151, 10.1016/j.cell.2006.10.029
Motoike, 2003, Evidence for novel fate of Flk1+ progenitor: Contribution to muscle lineage, Genesis, 35, 153, 10.1002/gene.10175
Murry, 2008, Differentiation of embryonic stem cells to clinically relevant populations: lessons from embryonic development, Cell, 132, 661, 10.1016/j.cell.2008.02.008
Narazaki, 2008, Directed and systematic differentiation of cardiovascular cells from mouse induced pluripotent stem cells, Circulation, 118, 498, 10.1161/CIRCULATIONAHA.108.769562
Ng, 2005, The primitive streak gene Mixl1 is required for efficient haematopoiesis and BMP4-induced ventral mesoderm patterning in differentiating ES cells, Development, 132, 873, 10.1242/dev.01657
Nostro, 2008, Wnt, activin, and BMP signaling regulate distinct stages in the developmental pathway from embryonic stem cells to blood, Cell Stem Cell, 2, 60, 10.1016/j.stem.2007.10.011
Nostro, 2011, Stage specific signaling through TGFβ family members and WNT regulates patterning and pancreatic specification of human pluripotent stem cells, Development, 10.1242/dev.055236
Paige, 2010, Endogenous Wnt/beta-catenin signaling is required for cardiac differentiation in human embryonic stem cells, PLoS ONE, 5, e11134, 10.1371/journal.pone.0011134
Park, 2004, A hierarchical order of factors in the generation of FLK1- and SCL-expressing hematopoietic and endothelial progenitors from embryonic stem cells, Development, 131, 2749, 10.1242/dev.01130
Park, 2008, Reprogramming of human somatic cells to pluripotency with defined factors, Nature, 451, 141, 10.1038/nature06534
Pfannkuche, 2009, Cardiac myocytes derived from murine reprogrammed fibroblasts: intact hormonal regulation, cardiac ion channel expression and development of contractility, Cell. Physiol. Biochem., 24, 73, 10.1159/000227815
Prall, 2007, A. Nkx2-5/Bmp2/Smad1 negative feedback loop controls heart progenitor specification and proliferation, Cell, 128, 947, 10.1016/j.cell.2007.01.042
Ruzicka, 1988, Sequential activation of alpha-actin genes during avian cardiogenesis: Vascular smooth muscle alpha-actin gene transcripts mark the onset of cardiomyocyte differentiation, J. Cell Biol., 107, 2575, 10.1083/jcb.107.6.2575
Saga, 1996, MesP1: A novel basic helix-loop-helix protein expressed in the nascent mesodermal cells during mouse gastrulation, Development, 122, 2769, 10.1242/dev.122.9.2769
Saga, 1999, MesP1 is expressed in the heart precursor cells and required for the formation of a single heart tube, Development, 126, 3437, 10.1242/dev.126.15.3437
Schneider, 2001, Wnt antagonism initiates cardiogenesis in Xenopus laevis, Genes Dev., 15, 304, 10.1101/gad.855601
Schultheiss, 1997, A role for bone morphogenetic proteins in the induction of cardiac myogenesis, Genes Dev., 11, 451, 10.1101/gad.11.4.451
Stadtfeld, 2008, Defining molecular cornerstones during fibroblast to iPS cell reprogramming in mouse, Cell Stem Cell, 2, 230, 10.1016/j.stem.2008.02.001
Sugi, 1992, Onset of expression and regional deposition of alpha-smooth and sarcomeric actin during avian heart development, Dev. Dyn., 193, 116, 10.1002/aja.1001930203
Thisse, 2000, Activin- and Nodal-related factors control antero-posterior patterning of the zebrafish embryo, Nature, 403, 425, 10.1038/35000200
Tzahor, 2001, Wnt signals from the neural tube block ectopic cardiogenesis, Genes Dev., 15, 255, 10.1101/gad.871501
Ueno, 2007, Biphasic role for Wnt/beta-catenin signaling in cardiac specification in zebrafish and embryonic stem cells, Proc. Natl. Acad. Sci. USA, 104, 9685, 10.1073/pnas.0702859104
Yang, 2008, Human cardiovascular progenitor cells develop from a KDR+ embryonic-stem-cell-derived population, Nature, 453, 524, 10.1038/nature06894
Yatskievych, 1997, Induction of cardiac myogenesis in avian pregastrula epiblast: The role of the hypoblast and activin, Development, 124, 2561, 10.1242/dev.124.13.2561
Ying, 2003, BMP induction of Id proteins suppresses differentiation and sustains embryonic stem cell self-renewal in collaboration with STAT3, Cell, 115, 281, 10.1016/S0092-8674(03)00847-X
Yu, 2008, Dorsomorphin inhibits BMP signals required for embryogenesis and iron metabolism, Nat. Chem. Biol., 4, 33, 10.1038/nchembio.2007.54