Specificity in V(D)J recombination: new lessons from biochemistry and genetics
Tài liệu tham khảo
Gellert, 1992, Molecular analysis of V(D)J recombination, Annu Rev Genet, 22, 425, 10.1146/annurev.ge.26.120192.002233
Lewis, 1994, The mechanism of V(D)J joining: lessons from molecular, immunological, and comparative analyses, Adv Immunol, 56, 27, 10.1016/S0065-2776(08)60450-2
Schatz, 1989, The V(D)J recombination activating gene, RAG-1, Cell, 59, 1035, 10.1016/0092-8674(89)90760-5
Oettinger, 1990, RAG-1 and RAG-2, adjacent genes that synergistically activate V(D)J recombination, Science, 248, 1517, 10.1126/science.2360047
Schwarz, 1996, RAG mutations in human B cell-negative SCID, Science, 274, 97, 10.1126/science.274.5284.97
Roth, 1992, V(D)J recombination in mouse thymocytes: double-strand breaks near T cell receptor δ rearrangement signals, Cell, 69, 41, 10.1016/0092-8674(92)90117-U
Schlissel, 1993, Double-strand signal sequence breaks in V(D)J recombination are blunt, 5'-phosphorylated, RAG-dependent, and cell-cycle-regulated, Genes Dev, 7, 2520, 10.1101/gad.7.12b.2520
Ramsden, 1995, Formation and resolution of double strand break intermediates in V(D)J rearrangement, Genes Dev, 9, 2409, 10.1101/gad.9.19.2409
Steen, 1996, The 12/23 rule is enforced at the cleavage step of V(D)J recombination in vivo, Genes to Cells, 1, 543, 10.1046/j.1365-2443.1996.d01-259.x
Roth, 1993, Characterization of broken DNA molecules associated with V(D)J recombination, Proc Natl Acad Sci USA, 90, 10788, 10.1073/pnas.90.22.10788
Roth, 1992, V(D)J recombination: broken DNA molecules with covalently sealed (hairpin) coding ends in scid mouse thymocytes, Cell, 70, 983, 10.1016/0092-8674(92)90248-B
Zhu, 1995, Characterization of coding ends in thymocytes of scid mice: implications for the mechanism of V(D)J recombination, Immunity, 2, 101, 10.1016/1074-7613(95)90082-9
Van Gent, 1995, Initiation of V(D)J recombination in a cell-free system, Cell, 81, 925, 10.1016/0092-8674(95)90012-8
McBlane, 1995, Cleavage at a V(D)J recombination signal requires only RAG1 and RAG2 proteins and occurs in two steps, Cell, 83, 387, 10.1016/0092-8674(95)90116-7
Van Gent, 1996, Similarities between initiation of V(D)J recombination and retroviral integration, Science, 271, 1592, 10.1126/science.271.5255.1592
Mizuuchi, 1991, Inversion of the phosphate chirality at the target site of Mu DNA strand transfer: evidence for a one-step transesterification mechanism, Cell, 66, 129, 10.1016/0092-8674(91)90145-O
Engelman, 1991, HIV-1 DNA integration: mechanism of viral DNA cleavage and DNA strand transfer, Cell, 67, 1211, 10.1016/0092-8674(91)90297-C
Vink, 1991, Site-specific hydrolysis and alcoholysis of human immunodeficiency virus DNA termini mediated by the viral integrase protein, Nucleic Acids Res, 19, 6691, 10.1093/nar/19.24.6691
Thompson, 1995, New insights into V(D)J recombination and its role in the evolution of the immune system, Immunity, 3, 531, 10.1016/1074-7613(95)90124-8
Dreyfus, 1992, Evidence suggesting an evolutionary relationship between transposable elements and immune system recombination sequences, Mol Immunol, 29, 807, 10.1016/0161-5890(92)90191-Y
Hesse, 1989, V(D)J recombination: a functional definition of the joining signals, Genes Dev, 3, 1053, 10.1101/gad.3.7.1053
Cuomo, 1996, DNA sequence and structure requirements for cleavage of V(D)J recombination signal sequences, Mol Cell Biol, 16, 5683, 10.1128/MCB.16.10.5683
Ramsden, 1996, Distinct DNA sequence and structure requirements for the two steps of V(D)J recombination signal cleavage, EMBO J, 15, 3197, 10.1002/j.1460-2075.1996.tb00682.x
Difilippantonio, 1996, RAG1 mediates signal sequence recognition and recruitment of RAG2 in V(D)J recombination, Cell, 87, 253, 10.1016/S0092-8674(00)81343-4
Spanopoulou, 1996, The homeodomain region of Rag-1 reveals the parallel mechanisms of bacterial and V(D)J recombination, Cell, 87, 263, 10.1016/S0092-8674(00)81344-6
Hiom, 1997, A stable RAG1-RAG2-DNA complex that is active in V(D)J cleavage, Cell, 10.1016/S0092-8674(00)81859-0
Van Gent, 1996, The RAG1 and RAG2 proteins establish the 12/23 rule in V(D)J recombination, Cell, 85, 107, 10.1016/S0092-8674(00)81086-7
Sheehan, 1993, V(D)J recombination: signal and coding joint resolution are uncoupled and depend on parallel synapsis of the sites, Mol Cell Biol, 13, 1363, 10.1128/MCB.13.3.1363
Eastman, 1996, Initiation of V(D)J recombination in vitro obeying the 12/23 rule, Nature, 380, 85, 10.1038/380085a0
Sadofsky, 1995, RAG-1 mutations that affect the target specificity of V(D)J recombination: a possible direct role of RAG-1 in site recognition, Genes Dev, 9, 2193, 10.1101/gad.9.17.2193
Roman, 1996, Genetic evidence that the RAG1 protein directly participates in V(D)J recombination through substrate recognition, Proc Natl Acad Sci USA, 93, 2333, 10.1073/pnas.93.6.2333
Bogue, 1996, Mechanism of V(D)J recombination, Curr Opin Immunol, 8, 175, 10.1016/S0952-7915(96)80055-0
Blunt, 1995, Defective DNA-dependent protein kinase activity is linked to V(D)J recombination and DNA repair defects associated with the murine scid mutation, Cell, 80, 813, 10.1016/0092-8674(95)90360-7
Kirchgessner, 1995, DNA-dependent kinase (p350) as a candidate gene for the murine SCID defect, Science, 267, 1178, 10.1126/science.7855601
Peterson, 1995, Loss of the catalytic subunit of the DNA-dependent protein kinase in DNA double-strand-break-repair mutant mammalian cells, Proc Natl Acad Sci USA, 92, 3171, 10.1073/pnas.92.8.3171
Blunt, 1996, Identification of a nonsense mutation in the carboxyterminal region of DNA-dependent protein kinase catalytic subunit in the scid mouse, Proc Natl Acad Sci USA, 93, 10285, 10.1073/pnas.93.19.10285
Danska, 1996, Biochemical and genetic defects in the DNA-dependent protein kinase in murine scid lymphocytes, Mol Cell Biol, 16, 5507, 10.1128/MCB.16.10.5507
Wiler, 1995, Equine severe combined immunodeficiency: a defect in V(D)J recombination and DNA-dependent protein kinase activity, Proc Natl Acad Sci USA, 92, 11485, 10.1073/pnas.92.25.11485
Nussenzweig, 1996, Requirement for Ku80 in growth and immunoglobulin V(D)J recombination, Nature, 382, 551, 10.1038/382551a0
Zhu, 1996, Ku86-deficient mice exhibit severe combined immunodeficiency and defective processing of V(D)J recombination intermediates, Cell, 86, 379, 10.1016/S0092-8674(00)80111-7
Li, 1995, The XRCC4 gene encodes a novel protein involved in DNA double-strand break repair and V(D)J recombination, Cell, 83, 1079, 10.1016/0092-8674(95)90135-3
Stanhope-Baker, 1996, Cell type-specific chromatin structure determines the targeting of V(D)J recombinase activity in vitro, Cell, 85, 887, 10.1016/S0092-8674(00)81272-6