Species concepts for trypanosomes: from morphological to molecular definitions?
Tóm tắt
The way species and subspecies names are applied in African trypanosomes of subgenera Trypanozoon and Nannomonas is reviewed in the light of data from molecular taxonomy. In subgenus Trypanozoon the taxonomic importance of pathogenicity, host range and distribution appear to have been inflated relative to actual levels of genetic divergence. The opposite is true for subgenus Nannomonas, where current taxonomic usage badly underrepresents genetic diversity. Data from molecular characterisation studies are revealing a growing number of genotypes, which may represent distinct taxa. Unfortunately few of these genotypes are yet supported by sufficient biological data to be recognized taxonomically. But we may be missing fundamental epidemiological information, because of our inability to distinguish these trypanosomes in host blood morphologically or in tsetse by their developmental cycle. Molecular taxonomy has led the way in identifying these new genotypes and now offers the key to elucidating the biology of these organisms.
Tài liệu tham khảo
Hoare CA: The Trypanosomes of Mammals. 1972, Oxford, Blackwell Scientific Publications
Lun ZR, Brun R, Gibson WC: Kinetoplast DNA and molecular karyotypes of Trypanosoma evansi and T. equiperdum from China. Molecular and Biochemical Parasitology. 1992, 50: 189-196. 10.1016/0166-6851(92)90215-6.
Riou G, Saucier J: Characterization of the molecular components in kinetoplast-mitochondrial DNA of Trypanosoma equiperdum. Comparative study of dyskineto-plastic and wild strains. Journal of Cell Biology. 1979, 82: 248-263.
Frasch A, Hajduk S, Hoeijmakers J, Borst P, Brunel F, Davison J: The kinetoplast DNA of Trypanosoma equiperdum. Biochimica et Biophysica Acta. 1979, 607: 397-410.
Gibson WC, Wilson AJ, Moloo SK: Characterisation of Trypanosoma (Trypanozoon) evansi from camels in Kenya using isoenzyme electrophoresis. Research in Veterinary Science. 1983, 34: 114-118.
Masiga DK, Gibson WC: Specific probes for Trypanosoma (Trypanozoon) evansi based on kinetoplast DNA mini-circles. Molecular and Biochemical Parasitology. 1990, 40: 279-284. 10.1016/0166-6851(90)90049-R.
Stevens JR, Noyes H, Dover GA, Gibson WC: The ancient and divergent origins of the human pathogenic trypanosomes, Trypanosoma brucei and T-cruzi. Parasitology. 1999, 118: 107-116. 10.1017/S0031182098003473.
Biteau N, Bringaud F, Gibson W, Truc P, Baltz T: Characterization of Trypanozoon isolates using a repeated coding sequence and microsatellite markers. Molecular and Biochemical Parasitology. 2000, 105: 185-201. 10.1016/S0166-6851(99)00171-1.
Jenni L, Marti S, Schweizer J, Betschart B, Lepage RWF, Wells JM, Tait A, Paindavoine P, Pays E, Steinert M: Hybrid formation between African trypanosomes during cyclical transmission. Nature. 1986, 322: 173-175.
Tait A, Barry JD, Wink R, Sanderson A, Crowe JS: Enzyme variation in Trypanosoma brucei spp. II. Evidence for T. b. rhodesiense being a set of variants of T. b. brucei. Parasitology. 1985, 90: 89-100.
Hide G, Buchanan N, Welburn S, Maudlin I, Barry JD, Tait A: Trypanosoma brucei rhodesiense: characterisation of stocks from Zambia, Kenya, and Uganda using repetitive DNA probes. Experimental Parasitology. 1991, 72: 430-439.
Hide G, Cattand P, Le Ray D, Barry DJ, Tait A: The identification of Trypanosoma brucei subspecies using repetitive DNA sequences. Molecular and Biochemical Parasitology. 1990, 39: 213-226. 10.1016/0166-6851(90)90060-Y.
Gibson WC, Marshall T.F. de C., Godfrey DG: Numerical analysis of enzyme polymorphism: a new approach to the epidemiology and taxonomy of trypanosomes of the subgenus Trypanozoon. Advances in Parasitology. 1980, 18: 175-246.
Gibson WC: Analysis of a genetic cross between Trypanosoma brucei rhodesiense and T. b. brucei. Parasitology. 1989, 99: 391-402.
De Greef C, Imberechts H, Matthyssons G, Van Meirvenne N, Hamers R: A gene expressed only in serum-resistant variants of Trypanosoma brucei rhodesiense. Molecular and Biochemical Parasitology. 1989, 36: 169-176. 10.1016/0166-6851(89)90189-8.
Gibson W: Will the real Trypanosoma brucei rhodesiense please step forward?. Trends Parasitol. 2002, 18: 486-490. 10.1016/S1471-4922(02)02390-5.
Xong VH, Vanhamme L, Chamekh M, Chimfwembe CE, Van den Abbeele J, Pays A, Van Meirvenne N, Hamers R, De Baetselier P, Pays E: A VSG expression site-associated gene confers resistance to human serum in Trypanosoma rhodesiense. Cell. 1998, 95: 839-846.
Godfrey DG, Baker RD, Rickman LR, Mehlitz D: The distribution, relationships and identification of enzymic variants within the subgenus Trypanozoon. Advances in Parasitology. 1990, 29: 1-74.
Mathieu-Daude F, Tibayrenc M: Isozyme variability of Trypanosoma brucei s.l.: genetic, taxonomic, and epidemiological significance. Experimental Parasitology. 1994, 78: 1-19. 10.1006/expr.1994.1001.
Dero B., Zampetti-Bosseler, F., Pays, E., Steinert, M.: The genome and the antigen gene repertoire of Trypanosoma brucei gambiense are smaller than those of T. b. brucei. Molecular and Biochemical Parasitology. 1987, 26: 247-256. 10.1016/0166-6851(87)90077-6.
Gibson WC: Will the real Trypanosoma brucei gambiense please stand up?. Parasitology Today. 1986, 2: 255-257. 10.1016/0169-4758(86)90011-6.
Godfrey DG, Kilgour V: Enzyme electrophoresis in characterising the causative organism of Gambian trypanosomiasis. Transactions of the Royal Society of Tropical Medicine and Hygiene. 1976, 70: 219-224.
Paindavoine P, Zampetti-Bosseler F, Coquelet H, Pays E, Steinert M: Different allele frequencies in Trypanosoma brucei brucei and Trypanosoma brucei gambiense populations. Molecular and Biochemical Parasitology. 1989, 32: 61-72. 10.1016/0166-6851(89)90130-8.
Paindavoine P., Pays, E., Laurent, M., Geltmeyer, Y., Le Ray, D., Mehlitz, D., Steinert, M.: The use of DNA hybridisation and numerical taxonomy in determining relationships between Trypanosoma brucei stocks and subspecies. Parasitology. 1986, 92: 31-50.
Radwanska M, Chamekh M, Vanhamme L, Claes F, Magez S, Magnus E, De Baetselier P, Buscher P, Pays E: The serum resistance-associated gene as a diagnostic tool for the detection of Trypanosoma brucei rhodesiense. Am. J. Trop. Med. Hyg. 2002, 67: 684-690.
Gibson W, Backhouse T, Griffiths A: The human serum resistance associated gene is ubiquitous and conserved in Trypanosoma brucei rhodesiense throughout East Africa. Infection, Genetics and Evolution. 2002, 1: 207-214. 10.1016/S1567-1348(02)00028-X.
Mehlitz D, Zillmann U, Scott CM, Godfrey DG: Epidemiological studies on the animal reservoir of gambiense sleeping sickness. III. Characterisation of Trypanozoon stocks by isoenzymes and sensitivity to human serum. Tropenmedizin und Parasitologie. 1982, 33: 113-118.
Kanmogne G.D., Bailey, M., Gibson, W.: Wide variation in DNA content among Trypanosoma brucei ssp. isolates. Acta Tropica. 1997, 63: 75-87. 10.1016/S0001-706X(96)00600-6.
McNamara JJ, Mohammed G, Gibson WC: Trypanosoma (Nannomonas) godfreyi sp. nov. from tsetse-flies in The Gambia: biological and biochemical characterization. Parasitology. 1994, 109: 497-509.
Majiwa P.A.O., Masake, R.A., Nantulya, V.N., Hamers, R., Matthyssons, G.: Trypanosoma congolense: identification of two karyotypic groups. EMBO Journal. 1985, 4: 3307-3313.
Majiwa PAO, Maina M, Waitumbi JN, Mihok S, Zweygarth E: Trypanosoma (Nannomonas) congolense: molecular characterisation of a new genotype from Tsavo, Kenya. Parasitology. 1993, 106: 151-162.
Young CJ, Godfrey DG: Enzyme polymorphism and the distribution of Trypanosoma congolense isolates. Annals of Tropical Medicine and Parasitology. 1983, 77: 467-481.
Gashumba JK: Two enzymically distinct groups of Trypanosoma congolense. Research in Veterinary Science. 1986, 40: 411-412.
Gibson WC, Stevens JR, Mwendia CMT, Makumi JN, Ngotho JM, Ndung'u JM: Unravelling the phylogenetic relationships of African trypanosomes of suids. Parasitology. 2001, 122: 625-631. 10.1017/S0031182001007880.
Knowles G,, Betschart B,, Kukla BA,, Scott JR,, Majiwa PAO: Genetically discrete populations of Ifrom livestock on the Kenyan Coast. Parasitology. 1988, 96: 461-474.
Masiga DK, McNamara JJ, Gibson WC: A repetitive DNA sequence specific for Trypanosoma (Nannomonas) godfreyi. Veterinary Parasitology. 1996, 62: 27-33. 10.1016/0304-4017(95)00847-0.
Gibson WC, Dukes P, Gashumba JK: Species-specific DNA probes for the identification of trypanosomes in tsetse. Parasitology. 1988, 97: 63-73.
Majiwa PAO, Webster P: A repetitive DNA sequence distinguishes Trypanosoma simiae from T. congolense. Parasitology. 1987, 95: 543-598.
Kukla BA, Majiwa PAO, Young CJ, Moloo SK, Ole-Moiyoi OK: Use of species-specific DNA probes for the detection and identification of trypanosome infections in tsetse flies. Parasitology. 1987, 95: 1-26.
Sloof P, Bos JL, Konings AFJM, Menke HH, Borst P, Gutteridge WE, Leon W: Characterisation of satellite DNA in Trypanosoma brucei and Trypanosoma cruzi. Journal of Molecular Biology. 1983, 167: 1-21.
Gibson WC, Borst P: Size-fractionation of the small chromosomes of Trypanozoon and Nannomonas trypanosomes by pulsed field gradient gel electrophoresis. Molecular and Biochemical Parasitology. 1986, 18: 127-140. 10.1016/0166-6851(86)90033-2.
Majiwa PAO, Hamers R, Van Meirvenne N, Matthyssens G: Evidence for genetic diversity in Trypanosoma (Nannomonas) congolense. Parasitology. 1986, 93: 291-304.
Garside LH, Gibson WC: Molecular characterisation of trypanosome species and subgroups within subgenus Nannomonas. Parasitology. 1995, 111: 301-312.
Masiga DK, Smyth AJ, Hayes PJ, Bromidge TJ, Gibson WC: Sensitive detection of trypanosomes in tsetse flies by DNA amplification. International Journal for Parasitology. 1992, 22: 909-918. 10.1016/0020-7519(92)90047-O.
Asbeck K, Ruepp S, Roditi I, Gibson W: GARP is highly conserved among Trypanosoma congolense Savannah, Forest and Kilifi subgroups. Molecular and Biochemical Parasitology. 2000, 106: 303-306. 10.1016/S0166-6851(99)00217-0.
Asbeck K, Kurath U, Roditi I, Gibson W: Trypanosoma (Nannomonas) simiae and T. (N.) godfreyi have genes encoding glutamic acid and alanine-rich proteins. Mol Biochem Parasitol. 2003
Masiga D.K., McNamara, J.J., Laveissiere, C., Truc, P., Gibson, W.C.: A high prevalence of mixed trypanosome infections in tsetse flies in Sinfra, Cote d'Ivoire detected by DNA amplification. Parasitology. 1996, 112: 75-80.
Majiwa PAO, Otieno LH: Recombinant DNA probes reveal simultaneous infection of tsetse flies with different trypanosome species. Molecular and Biochemical Parasitology. 1990, 40: 245-254. 10.1016/0166-6851(90)90046-O.
Nyeko JHP, Ole-Moiyoi OK, Majiwa P, Otieno LH, Ociba PM: Characterisation of trypanosome isolates from cattle in Uganda using species-specific DNA probes reveals predominance of mixed infections. Insect Science and Its Application. 1990, 11: 271-280.
Lehane MJ, Msangi AR, Whitaker CJ, Lehane SM: Grouping of trypanosome species in mixed infections in Glossina pallidipes. Parasitology. 2000, 120: 583-592. 10.1017/S0031182099005983.
Woolhouse ME, Hargrove JW, McNamara JJ: Epidemiology of trypanosome infections of the tsetse fly Glossina pallidipes in the Zambezi Valley. Parasitology. 1993, 106: 479-485.