Sparse dictionary learning recovers pleiotropy from human cell fitness screens

Cell Systems - Tập 13 - Trang 286-303.e10 - 2022
Joshua Pan1,2,3, Jason J. Kwon1,2,3, Jessica A. Talamas1,2,3, Ashir A. Borah2, Francisca Vazquez2, Jesse S. Boehm2, Aviad Tsherniak2, Marinka Zitnik2,4,5, James M. McFarland2, William C. Hahn1,2,3,6
1Dana-Farber Cancer Institute, Department of Medical Oncology, Boston, MA 02215, USA
2Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA
3Harvard Medical School, Boston, MA 02215, USA
4Harvard Medical School, Department of Biomedical Informatics, Boston, MA 02215, USA
5Harvard University, Data Science Initiative, Cambridge, MA 02138, USA
6Brigham and Women’s Hospital and Harvard Medical School, Department of Medicine, Boston, MA 02215, USA

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