Solitary Langerhans Cell Histiocytoma: An Unusual Form of Hashimoto‐Pritzker Histiocytosis?

Pediatric Dermatology - Tập 7 Số 4 - Trang 299-302 - 1990
Isabelle Masouyé1, Pierre Chavaz1, Oscar Daniel Salomón1, J. Balderer2, Pierre Carraux1, J.‐H. Saurat1
1Clinique de Dermatologie, Hôpital Cantonal Universitaire, Geneva, Switzerland
2Derrnatologie, Ferney‐Voltaire, France

Tóm tắt

Abstract: A 2‐month‐old girt acutely developed a brownish, firm nodule on the left thigh. The lesion was surgically removed when the patient was age 3 months, and histology showed a massive dermal infiltration by large histiocytic cells with abundant ground glass cytoplasm. Most cells were S100 protein positive. Electron microscopic examination revealed the presence of Birbeck granules in about 30% of the histiocytes, as well as laminated dense bodies and wormlike bodies. No recurrence was observed during follow‐up for three years. We believe that this case, like the one previously reported, represents a clinical variant of Hashimoto‐Pritzker disease.

Từ khóa


Tài liệu tham khảo

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