Solid‐phase microextraction: a powerful sample preparation tool prior to mass spectrometric analysis

Journal of Mass Spectrometry - Tập 39 Số 3 - Trang 233-254 - 2004
György Vas1, Károly Vékey
1Department of Biomedical Mass Spectrometry, University of Antwerp, Universiteitsplein 1, B-2610 Wilrijk, Belgium. [email protected]

Tóm tắt

AbstractSample preparation is an essential step in analysis, greatly influencing the reliability and accuracy of resulted the time and cost of analysis. Solid‐Phase Microextraction (SPME) is a very simple and efficient, solventless sample preparation method, invented by Pawliszyn in 1989. SPME has been widely used in different fields of analytical chemistry since its first applications to environmental and food analysis and is ideally suited for coupling with mass spectrometry (MS). All steps of the conventional liquid–liquid extraction (LLE) such as extraction, concentration, (derivatization) and transfer to the chromatograph are integrated into one step and one device, considerably simplifying the sample preparation procedure. It uses a fused‐silica fibre that is coated on the outside with an appropriate stationary phase. The analytes in the sample are directly extracted to the fibre coating. The SPME technique can be routinely used in combination with gas chromatography, high‐performance liquid chromatography and capillary electrophoresis and places no restriction on MS. SPME reduces the time necessary for sample preparation, decreases purchase and disposal costs of solvents and can improve detection limits. The SPME technique is ideally suited for MS applications, combining a simple and efficient sample preparation with versatile and sensitive detection. This review summarizes analytical characteristics and variants of the SPME technique and its applications in combination with MS. Copyright © 2004 John Wiley & Sons, Ltd.

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Tài liệu tham khảo

10.1016/S0021-9673(03)00511-9

10.1021/ac034094h

10.2166/wqrj.1989.010

10.1021/ac00218a019

10.1016/S0021-9673(00)00309-5

Science Citation Index 2003

Pawliszyn J, 1998, Solid Phase Microextraction: Theory and Practice

10.1039/9781847550149

Wercinski SCS, 1999, Solid Phase Microextraction—A Practical Guide

10.1016/0165-9936(95)94044-F

10.1016/0021-9673(95)00875-6

10.1016/S0021-9673(00)00934-1

10.1016/S0021-9673(00)00767-6

10.1021/ac00111a006

10.1039/a808487d

10.1016/S1570-0232(02)00069-7

10.1093/chromsci/36.10.505

Kolb B, 1997, Static Headspace‐Gas chromatography: Theory and Practice

10.1021/ac9606362

10.1021/ac0343230

LordLH WallesM GrantRP IncledonB FahieB PawliszynJ.presented at the 51st Conference on Mass Spectrometry and Allied Topics Montreal June2003.

10.1016/S0039-9140(01)00316-2

10.1016/S0021-9673(00)01025-6

10.1002/jms.393

10.1021/ac034218q

Mullet WM, 2002, Anal. Chem., 74, 1695, 10.1021/ac015723v

10.1007/s00216-002-1269-z

10.1016/S0021-9673(03)00307-8

10.1039/b000544o

10.1007/BF02497674

10.1016/S0021-9673(02)01333-X

10.1007/s00216-002-1349-0

10.1016/S0731-7085(02)00522-8

10.1002/(SICI)1520-667X(1999)11:10<737::AID-MCS7>3.0.CO;2-4

10.1021/ac00073a027

10.1016/S0378-4347(98)00156-X

10.1016/S0021-9673(97)00179-9

10.1016/S0021-9673(99)01350-3

Okeyo P, 1997, J. High Resolut. Chromatogr., 20, 129, 10.1002/jhrc.1240200309

10.1016/S0378-4347(97)00526-4

10.1021/ac9711394

10.1016/0379-0738(95)01874-3

A Practical Guide to Quantitation with SPME. Supelco Bulletin 929 T: 101929 2001. Supelco: Bellefonte PA.

10.1016/0021-9673(95)01338-5

10.1016/S0045-6535(00)00047-3

10.1016/S0021-9673(02)00543-5

10.1016/S0003-2670(02)00600-1

10.1021/ac020124p

10.1016/S0021-9673(02)00542-3

10.1016/S0021-9673(02)00217-0

TamiriT.Presented at the 51st Conference on Mass Spectrometry and Allied Topics Montreal June2003.

10.1016/S0021-9673(99)00873-0

10.1016/S0021-9673(01)01523-0

10.1016/S0021-9673(99)01256-X

10.1021/ac00062a008

10.1021/ac00097a007

10.1002/jhrc.1240190908

10.1021/ac960905o

10.1016/0021-9673(94)01177-G

10.1016/S0021-9673(02)00644-1

10.1016/S1387-3806(98)14091-5

10.1016/S0045-6535(02)00845-7

10.1016/S0021-9673(98)00466-X

10.1016/S0021-9673(97)00132-5

10.1016/0021-9673(96)00298-1

Svendsen MR, 2002, Atmos. Environ., 36, 3909, 10.1016/S1352-2310(02)00335-7

De AngelisF.21st Informal Meeting on Mass Spectrometry May 11–15 2003 Antwerp Book of Abstracts;69.

10.1016/S0165-9936(02)00708-2

10.1016/S0021-9673(02)00222-4

10.1016/S0003-2670(02)01410-1

10.1002/jhrc.1240161203

10.1016/S0021-9673(00)00347-2

10.1016/S0021-9673(99)00171-5

10.1016/S0021-9673(99)00850-X

10.1016/1044-0305(95)00527-7

10.1016/S0021-9673(97)00795-4

10.1016/S0021-9673(02)01280-3

10.1016/S0021-9673(01)01363-2

10.1016/S0021-9673(99)01284-4

10.1016/0021-9673(94)00794-2

10.1039/an9962100929

Tutschku S, 1996, Fresenius' J. Anal. Chem., 354, 587, 10.1007/s0021663540587

10.1021/ac950902w

10.1021/es00073a012

10.1016/0021-9673(95)00726-1

10.1016/0021-9673(94)01230-C

10.1016/0021-9673(95)00435-P

Fed. Reg. EPA Method 604 Phenols Part VIII 40 CFR Part 136. US EPA: Washington DC 16 October1984;58.

10.1016/S0021-9673(02)00646-5

10.1002/rcm.873

10.1016/S0021-9673(01)00920-7

10.1039/b204574e

10.1016/0021-9673(95)01349-0

10.1016/S0021-9673(99)01267-4

10.1016/S0003-2670(01)00893-5

10.1016/S0021-9673(01)01192-X

10.1016/S0021-9673(00)00874-8

10.1016/S0021-9673(99)00987-5

10.1016/S0378-4347(97)00611-7

Takamoto S, 2001, J. Chromatogr. B, 758, 123, 10.1016/S0378-4347(01)00152-9

10.1016/S0378-4347(01)00308-5

10.1016/S0003-2670(02)00090-9

Delzer GC, 1996, Water Resources Investigations Report 96‐4145

10.1016/S1352-2310(01)00423-X

10.1016/S0045-6535(00)00501-4

Zuccarello JL, 2003, Chemosphere

HoldakM TesniarzD WojtasikE Polec‐PawlakK JaroszM.21st Informal Meeting on Mass Spectrometry May 11–15 2003. Antwerp Book of Abstracts;71.

10.1016/S0021-9673(98)00080-6

10.1016/S0045-6535(02)00160-1

10.1016/S0003-2670(00)01153-3

10.1016/S0021-9673(03)01122-1

10.1016/S0269-7491(97)00019-5

10.1021/ac0258002

Vas G, 1999, Acta Aliment., 28, 95

Vas G, 1998, Am. J. Enol. Vitic., 49, 100, 10.5344/ajev.1998.49.1.100

10.1021/jf00045a018

10.1007/BF02492823

10.1006/jfca.2001.0987

HarangiJ VasGy.Identification of GC peaks—identification of GC chromatograms.20th International Symposium on Capillary Chromatography Riva del Garda Italy 25–29 May 1998 Book of AbstractsCD‐ROM Poster No. A11.

10.1016/S0021-9673(99)01282-0

10.1016/S0021-9673(02)00376-X

10.1016/S0278-6915(02)00230-2

10.1021/ac020296m

10.1016/S0021-9673(03)01066-5

10.1016/S0963-9969(99)00074-5

VasGy KozmaP LialiosA HarangiJ DobóA VékeyK.19th International Symposium on Capillary Chromatography and Electrophoresis Wintergreen USA 18–22 May 1997proc. 644–645.

VasGy KozmaP LialiosA HarangiJ DobóA VékeyK.14th International Mass Spectrometry Conference 25–29 August 1997 Tampere Finland Book of Abstracts;260.

10.1016/S0021-9673(01)01382-6

10.1016/S0021-9673(02)01445-0

10.1016/S0963-9969(97)00023-9

10.1039/B208577A

10.1016/S0021-9673(00)00990-0

10.1016/S0021-9673(02)02014-9

10.1016/S0021-9673(02)01220-7

10.1016/S0165-9936(01)00121-2

10.1016/S0021-9673(02)01072-5

10.1080/026520399284154

10.1016/S0021-9673(02)00211-X

10.1016/S0141-3910(98)00082-2

10.1016/S0021-9673(02)01829-0

10.1021/jf9707290

10.1016/S0021-9673(02)00167-X

Vas Gy, 1997, Supelco Rep., 16, 7

10.1081/FRI-100000517

10.1016/S0021-9673(97)00581-5

10.1016/S0003-2670(00)01103-X

10.1556/AAlim.28.1999.2.2

Lorincz Gy, 1997, Vitic. Enol. Sci., 53, 18

10.1016/S0021-9673(01)01421-2

10.1002/(SICI)1097-0231(19981115)12:21<1595::AID-RCM370>3.0.CO;2-N

10.1016/S0308-8146(02)00340-0

10.1002/jhrc.1240201209

10.1007/s002160050806

10.1002/(SICI)1521-4168(19980701)21:7<373::AID-JHRC373>3.0.CO;2-7

10.1016/S0021-9673(01)00966-9

10.1016/S0021-9673(02)00123-1

10.1002/mcs.1048

10.1002/rcm.675

10.1016/S0021-9673(02)01467-X

10.1002/jhrc.1240190504

David F, 2003, LC‐GC Eur., 16, 410

VasG. PerkinElmar chromatography training material for BorsodChem Ltd. Chapter 2.2001;28.

10.1126/science.275.5297.218

10.1016/S0021-9673(02)01471-1

10.1002/(SICI)1097-0231(199711)11:17<1926::AID-RCM97>3.0.CO;2-2

10.1007/s002160051224

10.1002/(SICI)1521-4168(19981201)21:12<665::AID-JHRC665>3.0.CO;2-Z

10.1016/S0378-4347(98)00515-5

Bergamaschi E, 1999, Toxicol. Lett., 108, 241, 10.1016/S0378-4274(99)00095-8

10.1016/0379-0738(95)01819-0

10.1016/S0378-4347(00)00554-5

10.1016/S0379-0738(96)02028-2

10.1039/b203898f

10.1016/S0731-7085(98)00240-4

10.1016/S0378-4347(98)00304-1

Poli D, 1999, J. Chromatogr. B, 732, 115, 10.1016/S0378-4347(99)00274-1

10.1016/S0378-4347(00)00312-1

10.1016/S0378-4347(98)00542-8

10.1016/S0021-9673(97)00363-4

10.1016/S0003-2670(98)00293-1

10.1016/S0378-4347(99)00071-7

10.1016/S0378-4347(01)00200-6

10.1016/S0378-4347(99)00237-6

10.1002/(SICI)1099-0801(199701)11:1<25::AID-BMC615>3.0.CO;2-Y

Liu JT, 1999, J. Chromatogr. A, 731, 217, 10.1016/S0378-4347(99)00226-1

10.1016/S0379-0738(97)00062-5

10.1016/S0021-9673(02)00216-9

10.1016/S0021-9673(00)00596-3

10.1016/S0379-0738(00)00145-6

10.1016/S0379-0738(00)00341-8

10.1016/S0378-4347(98)00081-4

10.1016/S0731-7085(02)00267-4

10.1016/S0379-0738(99)00158-9

10.1016/S1570-0232(02)00522-6

10.1016/S0378-4347(01)00119-0

Sporkert F, 2000, J. Chromatogr. B, 746, 255, 10.1016/S0378-4347(00)00344-3

10.1016/S0379-0738(99)00164-4

10.1016/S0379-0738(02)00412-7

10.1016/S1570-0232(02)00625-6

10.1016/S1537-5110(02)00240-4

10.1016/S0021-9673(03)01103-8

10.1046/j.1472-765X.2003.01305.x

10.1016/0167-7012(95)00093-3

10.1016/S0043-1354(97)00444-2

10.1016/S0167-7012(02)00190-2

Zhu PL, 2003, J. Chromatogr. A, 988, 25, 10.1016/S0021-9673(02)01994-5

10.1039/b204701b

WallesM TongH ThomsonB NacsonS PawliszynJ.presented at the 51st Conference on Mass Spectrometry and Allied Topics Montreal June2003.

10.1021/ac025884e

PillingerC.Beagle 2—Searching for life on Mars. 16th International Mass Spectrometry Conference 30 August–5 September 2003 Edinburgh UK plenary lecture.

10.1002/jms.327

10.1021/ac025880

10.1039/b308292j