Sodium nonivamide acetate: A non-pungently antinociceptive capsaicin derivative with unusual anti-inflammatory properties

Blackwell, 1995, Some characteristics of the prostaglandins synthesizing system in rabbit kidney microsomes, Biochim. Biophys. Acta., 398, 178, 10.1016/0005-2760(75)90181-2 Brand, 1990, Anti-inflammatory pharmacology and mechanism of the orally active capsaicin analogs, NE-19550 and NE-28345, Agents Actions, 31, 329, 10.1007/BF01997628 Chang, 1977, Identification of 6-ketoprostaglandin F1a formed from arachidonic acid in bovine seminal vesicles, Biochem. biophys. Acta, 486, 136, 10.1016/0005-2760(77)90078-9 Chen, 1984, Edema formation and degranulation of mast cells by Trimeresurus Mucrosquamatus snake venom, Toxicon, 22, 17, 10.1016/0041-0101(84)90134-X Chen, 1992, Hypotensive and antinociceptive effects of ether-linked and relatively non-pungent analogues of N-nonanoyl vanillylamide, Eur. J. med. Chem., 27, 187, 10.1016/0223-5234(92)90002-I Chignard, 1978, Synthesis of thromboxane B2 in incubates of dog platelet-rich plasma with arachidonic acid and its inhibition by different drugs, Biochem. biophys. Res. Commun., 85, 1631, 10.1016/0006-291X(78)91190-7 Chiu, 1989, Edema formation and degranulation of mast cells by a basic phospholipase A2 purified from Trimeresurus Mucrosquamatus snake venom, Toxicon, 27, 115, 10.1016/0041-0101(89)90411-X Collier, 1976, Stimulation of prostaglandin biosynthesis by drugs: effects in vitro of some drugs affecting gut function, Br. J. Pharmac., 58, 193, 10.1111/j.1476-5381.1976.tb10396.x Dewhirst, 1980, Structure-activity relationships for inhibition of prostaglandin cycloxygenase by phenolic compounds, Prostaglandins, 20, 209, 10.1016/S0090-6980(80)80040-2 Diamant, 1990, New insights into the mechanisms of histamine release from rat peritoneal mast cells, 142 Ferreira, 1973, Further experiments to establish the inhibition that the analgesic action of aspirin-like drugs depends on the inhibition of prostaglandin biosynthesis, Br. J. Pharmac., 47, 629P Fitzgerald, 1983, Capsaicin and sensory neurones-a review, Pain, 5, 109, 10.1016/0304-3959(83)90012-X Flower, 1972, Inhibition of prostaglandin synthetase in brain explains the anti-pyretic activity of paracetamol, Nature, Lond., 240, 410, 10.1038/240410a0 Flynn, 1986, Inhibition of human neutrophil 5-lipoxygenase activity by gingerdione, shogaol, capsaicin and related pungent compounds, Prostag. Leuk. Med., 24, 195, 10.1016/0262-1746(86)90126-5 Fredholm, 1980, Modulation of neurotransmission, Biochem. Pharmac., 29, 1635, 10.1016/0006-2952(80)90117-3 Higgs, 1984, Inhibition of tissue damage by the arachidonate lipoxygenase inhibitor BW755c, 81, 2890 Juan, 1974, Action of peptides and other algesic agents on paravascular pain receptors of the isolated perfused rabbit ear, Naunyn-Schmiedeberg's Arch. Pharmac., 283, 151, 10.1007/BF00501142 Juan, 1980, Nociceptor stimulation and PGE release by capsaicin, Naunyn-Schmiedeberg's Arch. Pharmac., 312, 139, 10.1007/BF00569722 Katharine, 1989, Evaluation of adenosine agonists as potential analgesics, Eur. J. Pharmac., 162, 365, 10.1016/0014-2999(89)90301-4 Kuichi, 1982, Inhibitors of prostaglandin biosynthesis from ginger, Chem. pharm. Bull., 30, 754, 10.1248/cpb.30.754 Lagunoff, 1983, Agents that release histamine from mast cells, Annu. Rev. Toxicol., 23, 331, 10.1146/annurev.pa.23.040183.001555 Litchfield, 1949, A simplified method of evaluating dose-effect experiments, J. Pharmac. exp. Ther., 96, 99 Lo, 1994, Autonomic and sensory cardiovascular activities of nonivamide: intrathecal administration of clonidine, Brain Res. Bull., 35, 15, 10.1016/0361-9230(94)90210-0 Marsh, 1987, The mechanism of action of capsaicin on sensory C-type neurons and their axons in vitro, Neuroscience, 23, 275, 10.1016/0306-4522(87)90289-2 Needleman, 1976, Thromboxanes: selective biosynthesis and distinct biological properties, Science, 193, 163, 10.1126/science.945611 Needleman, 1977, Application of imidazole as a selective inhibitor of thromboxane synthetase in human platelets, 74, 1716 Prancan, 1979, L8027 and 1-nonyl-imidazole as nonselective inhibitors of thromboxane synthesis, Eur. J. Pharmac., 60, 287, 10.1016/0014-2999(79)90232-2 Steranka, 1988, Bradykinin as a pain mediator: receptors are localized to sensory neurons, and antagonists have analgesic actions, 85, 3245 Sweeney, 1989, Morphine, capsaicin and K+ release purines from capsaicin-sensitive primary afferent nerve terminals in the spinal cord, J. Pharmac. exp. Ther., 248, 447 Snyder, 1985, Adenosine as a neuromodulator, Annu. Rev. Neurosci., 8, 103, 10.1146/annurev.ne.08.030185.000535 Takagi, 1971, Studies of the spontaneous movement of animals by the hole cross test: effect of 2-dimethylaminoethanol and its acyl esters on the central nervous system, Jpn J. Pharmac., 21, 797, 10.1254/jjp.21.797 Tallarida, 1987 Virus, 1981, Capsaicin treatment in adult Wistar-Kyoto and spontaneously hypertensive rats: effects on nociceptive behavior and cardiovascular regulation, Eur. J. Pharmac., 72, 209, 10.1016/0014-2999(81)90275-2 Wagner, 1986, Anti-inflammatory drugs. Part 3. In vitro inhibition of prostaglandin biosynthesis by essential oils and phenolic compounds, Planta Med., 3, 184, 10.1055/s-2007-969117 Whittle, 1964, The use of changes in capillary permeability in mice to distinguish between narcotic and nonnarcotic analgesics, Br. J. Pharmac., 22, 246 Yang, 1992, Depressor response of sodium nonivamide acetate: a newly synthesized nonpungent analogue of capsaicin, Asia Pacific J. Pharmac., 7, 95 Yang, 1993, Spinal adenosine modulates capsaicin-induced depressor reflex: involvement of adenosine A2 receptor, Gen. Pharmac., 24, 961, 10.1016/0306-3623(93)90174-V Yeh, 1987, Cyclooxygenase-independent pathway of phospholipase activation in carrageenin-induced platelet aggregation, Thromb. Res., 45, 39, 10.1016/0049-3848(87)90255-6