Sodium butyrate activates erythroid-specific 5-aminolevulinate synthase gene through Sp1 elements at its promoter

Bishop, 1990, Human delta-aminolevulinate synthase: assignment of the housekeeping gene to 3p21 and the erythroid-specific gene to the X chromosome, Genomics, 7, 207, 10.1016/0888-7543(90)90542-3 Meguro, 1995, The role of the erythroid-specific delta-aminolevulinate synthase gene expression in erythroid heme synthesis, Blood, 86, 940, 10.1182/blood.V86.3.940.940 Sadlon, 1999, Regulation of erythroid 5-aminolevulinate synthase expression during erythropoiesis, Int. J. Biochem. Cell Biol., 31, 1153, 10.1016/S1357-2725(99)00073-4 Fujiwara, 2006, Differential gene expression profiling between wild-type and ALAS2-null erythroblasts: identification of novel heme-regulated genes, Biochem. Biophys. Res. Commun., 340, 105, 10.1016/j.bbrc.2005.11.163 Nakajima, 1999, Heme deficiency in erythroid lineage causes differentiation arrest and cytoplasmic iron overload, EMBO J., 18, 6282, 10.1093/emboj/18.22.6282 Davie, 2003, Inhibition of histone deacetylase activity by butyrate, J. Nutr., 133, 2485S, 10.1093/jn/133.7.2485S Garcia-Manero, 2005, Histone deacetylase inhibitors: a review of their clinical status as antineoplastic agents, Cancer Invest., 23, 635, 10.1080/07357900500283119 Leder, 1975, Butyric acid, a potent inducer of erythroid differentiation in cultured erythroleukemic cells, Cell, 5, 319, 10.1016/0092-8674(75)90107-5 Wang, 2008, p300 plays a role in p16INK4a expression and cell cycle arrest, Oncogene, 27, 1894, 10.1038/sj.onc.1210821 Han, 2006, Histone acetyltransferase p300 regulates the transcription of human erythroid-specific 5-aminolevulinate synthase gene, Biochem. Biophys. Res. Commun., 348, 799, 10.1016/j.bbrc.2006.07.147 Yang, 2001, Sodium butyrate induces transcription from the G alpha(i2) gene promoter through multiple Sp1 sites in the promoter and by activating the MEK-ERK signal transduction pathway, J. Biol. Chem., 276, 25742, 10.1074/jbc.M102821200 Siavoshian, 2000, Butyrate and trichostatin A effects on the proliferation/differentiation of human intestinal epithelial cells: induction of cyclin D3 and p21 expression, Gut, 46, 507, 10.1136/gut.46.4.507 Lu, 1999, Transcriptional regulation by butyrate of mouse galectin-1 gene in embryonal carcinoma cells, Biochim. Biophys. Acta, 1444, 85, 10.1016/S0167-4781(98)00257-7 Walker, 2001, Butyrate, a histone deacetylase inhibitor, activates the human IGF binding protein-3 promoter in breast cancer cells: molecular mechanism involves an Sp1/Sp3 multiprotein complex, Endocrinology, 142, 3817, 10.1210/en.142.9.3817 Surinya, 1997, Transcriptional regulation of the human erythroid 5-aminolevulinate synthase gene, J. Biol. Chem., 272, 26585, 10.1074/jbc.272.42.26585 Doetzlhofer, 1999, Histone deacetylase 1 can repress transcription by binding to Sp1, Mol. Cell Biol., 19, 5504, 10.1128/MCB.19.8.5504 Cucciolla, 2008, Histone deacetylase inhibitors up-regulate p57Kip2 level by enhancing its expression through Sp1 transcription factor, Carcinogenesis, 29, 560, 10.1093/carcin/bgn010 Duan, 2005, Histone deacetylase inhibitors down-regulate bcl-2 expression and induce apoptosis in t(14;18) lymphomas, Mol. Cell Biol., 25, 1608, 10.1128/MCB.25.5.1608-1619.2005 Kiela, 2007, Molecular mechanism of rat NHE3 gene promoter regulation by sodium butyrate, Am. J. Physiol. Cell Physiol., 293, C64, 10.1152/ajpcell.00277.2006 Kaczynski, 2003, Sp1- and Krüppel-like transcription factors, Genome Biol., 4, 206, 10.1186/gb-2003-4-2-206 Schneider, 2004, Histone H3 lysine 4 methylation patterns in higher eukaryotic genes, Nat. Cell Biol., 6, 73, 10.1038/ncb1076 Kim, 2004, Developmental stage differences in chromatin subdomains of the β-globin locus, Proc. Natl. Acad. Sci. U. S. A., 101, 7028, 10.1073/pnas.0307985101