Snake venom metalloproteinases:Their role in the pathogenesis of local tissue damage

Gutiérrez, 1989, Local tissue damage induced by Bothrops snake venoms: a review, Memorias Instituto Butantan, 51, 211 Dart, 1992, The sequelae of pitviper poisoning in the United States, 395 Warrell, 1995, Clinical toxicology of snakebite in Asia, 493 Gutiérrez, 1997, Phospholipase A2 myotoxins from Bothrops snake venoms, 321 Ownby, 1990, Locally acting agents: myotoxins, hemorrhagic toxins and dermonecrotic factors, 602 Bjarnason, 1994, Hemorrhagic metalloproteinases from snake venoms, Pharmacol. Ther., 62, 325, 10.1016/0163-7258(94)90049-3 Kamiguti, 1996, Insights into the mechanism of hemorrhage caused by snake venom metalloproteinases, Toxicon, 34, 627, 10.1016/0041-0101(96)00017-7 Kamiguti, 1998, Snake venom metalloproteinases and disintegrins: interactions with cells, Braz. J. Med. Biol. Res., 31, 853, 10.1590/S0100-879X1998000700001 Hati, 1999, Snake venom hemorrhagins, Crit. Rev. Toxicol., 29, 1, 10.1080/10408449991349168 Gutiérrez, 1995, Skeletal muscle necrosis and regeneration after injection of BaH1, a hemorrhagic metalloproteinase isolated from the venom of the snake Bothrops asper (terciopelo), Exp. Mol. Pathol., 62, 28, 10.1006/exmp.1995.1004 Rucavado, 1998, Blister formation and skin damage induced by BaP1, a haemorrhagic metalloproteinase from the venom of the snake Bothrops asper, Int. J. Exp. Pathol., 79, 245 Gutiérrez, 1995, Isolation and characterization of a metalloproteinase with weak hemorrhagic activity from the venom of the snake Bothrops asper (terciopelo), Toxicon, 33, 19, 10.1016/0041-0101(94)00138-X Moura da Silva, 1996, Processing of pro-tumor necrosis factor-α by venom metalloproteinases: a hypothesis explaining local tissue damage following snake bite, Eur. J. Immunol., 26, 2000, 10.1002/eji.1830260905 Bode, 1993, Astacins, serralysins, snake venom and matrix metalloproteinases exhibit identical zinc-binding environments (HEXXHXXGXXH and Met-turn) and topologies and should be grouped into a common family, the ‘metzincins’, FEBS Lett., 331, 134, 10.1016/0014-5793(93)80312-I Hooper, 1994, Families of zinc metalloproteinases, FEBS Lett., 354, 1, 10.1016/0014-5793(94)01079-X Hite, 1994, cDNA sequences for four snake venom metalloproteinases: structure, classification, and their relationship to mammalian reproductive proteins, Arch. Biochem. Biophys., 308, 182, 10.1006/abbi.1994.1026 Stone, 1999, Structure-function analysis of the ADAM family of disintegrin-like and metalloproteinase-containing proteins (review), J. Prot. Chem., 18, 447, 10.1023/A:1020692710029 Markland, 1998, Snake venoms and the hemostatic system, Toxicon, 36, 1749, 10.1016/S0041-0101(98)00126-3 Paine, 1992, Purification, cloning and molecular characterization of a high molecular weight hemorrhagic metalloprotease, jararhagin, from Bothrops jararaca venom. Insights into the disintegrin gene family, J. Biol. Chem., 267, 22869, 10.1016/S0021-9258(18)50027-2 Kini, 1992, Structural domains in venom proteins: Evidence that metalloproteinases and nonenzymatic platelet aggregation inhibitors (disintegrins) from snake venoms are derived by proteolysis from a common precursor, Toxicon, 30, 265, 10.1016/0041-0101(92)90869-7 Hite, 1992, Sequence of a cDNA clone encoding the zinc metalloproteinase hemorrhagic toxin e from Crotalus atrox: evidence for signal, zymogen, and disintegrin-like structures, Biochemistry, 31, 6203, 10.1021/bi00142a005 Yamada, 1999, Nucleotide sequence of a cDNA encoding a common precursor of disintegrin flavostatin and hemorrhagic factor HR2a from the venom of Trimeresurus flavoviridis, FEBS Lett., 451, 299, 10.1016/S0014-5793(99)00604-3 Takeya, 1993, Primary structures of platelet aggregation inhibitors (disintegrins) autoproteolytically released from snake venom hemorrhagic metalloproteinases and new fluorogenic peptide substrates for these enzymes, J. Biochem., 113, 473, 10.1093/oxfordjournals.jbchem.a124069 Bjarnason, 1978, Hemorrhagic toxins from Western diamondback rattlesnake (Crotalus atrox) venom: isolation and characterization of five toxins and the role of zinc in hemorrhagic toxin e, Biochemistry, 17, 3395, 10.1021/bi00609a033 Takeya, 1990, The complete amino acid sequence of the high molecular mass hemorrhagic protein HR1B isolated from the venom of Trimeresurus flavoviridis, J. Biol. Chem., 265, 16068, 10.1016/S0021-9258(17)46189-8 Borkow, 1993, Isolation and characterization of synergistic hemorrhagins from the venom of the snake Bothrops asper, Toxicon, 31, 1137, 10.1016/0041-0101(93)90129-7 Gomis-Ruth, 1993, First structure of a venom metalloproteinase: a prototype for matrix metalloproteinases/collagenases, EMBO J., 12, 4151, 10.1002/j.1460-2075.1993.tb06099.x Zhang, 1994, Structure interaction of natural and synthetic inhibitors with the venom metalloproteinase atrolysin C (form-d), Proc. Natl. Acad. Sci. USA, 91, 8447, 10.1073/pnas.91.18.8447 Kumasawa, 1996, Crystal structure of H2-proteinase from the venom of Trimeresurus flavoviridis, J. Biochem., 119, 49, 10.1093/oxfordjournals.jbchem.a021215 Gong, 1998, Crystal structures of acutolysin A, a three-disulfide hemorrhagic zinc metalloproteinase from the snake venom of Agkistrodon acutus, J. Mol. Biol., 283, 657, 10.1006/jmbi.1998.2110 Willis, 1988, Purification and biochemical characterization of atroxase, a nonhemorrhagic fibrinolytic protease from Western diamondback rattlesnake venom, Biochemistry, 27, 4769, 10.1021/bi00413a028 Ownby, 1982, Pathology of rattlesnake envenomation, 163 Kondo, 1960, Studies on the quantitative method for determination of hemorrhagic activity of Habu snake venom, Jpn. J. Med. Sci. Biol., 13, 43, 10.7883/yoken1952.13.43 Theakston, 1983, Development of simple standard assay procedures for the characterization of snake venoms, Bull. WHO, 61, 949 Gutiérrez, 1985, Neutralization of proteolytic and hemorrhagic activities of Costa Rican snake venoms by a polyvalent antivenom, Toxicon, 23, 887, 10.1016/0041-0101(85)90380-0 Ownby, 1984, A new method for quantitating hemorrhage induced by rattlesnake venoms: ability of polyvalent antivenom to neutralize hemorrhagic activity, Toxicon, 22, 227, 10.1016/0041-0101(84)90023-0 De Roodt, 2000, A comparison of different methods to assess the hemorrhagic activity of Bothrops venoms, Toxicon, 38, 865, 10.1016/S0041-0101(99)00205-6 Mc Kay, 1970, The action of hemorrhagin and phospholipase derived from Vipera palestinae venom on the microcirculation, Lab. Invest., 22, 387 Ownby, 1978, Hemorrhagic toxins from rattlesnake (Crotalus atrox) venom. Pathogenesis of hemorrhage induced by three purified toxins, Am. J. Pathol., 93, 201 Ownby, 1990, Pathogenesis of hemorrhage induced by bilitoxin, a hemorrhagic toxin isolated from the venom of the common cantil (Agkistrodon bilineatus bilineatus), Toxicon, 28, 837, 10.1016/S0041-0101(09)80006-8 Ownby, 1987, Pathogenesis of hemorrhage induced by hemorrhagic proteinase IV from timber rattlesnake (Crotalus horridus horridus) venom, Toxicon, 25, 517, 10.1016/0041-0101(87)90287-X Rahmy, 1992, Cytopathologic effect of Cerastes cerastes (Egyptian sand viper) venom and isolated hemorrhagic toxin on liver and kidney: an electron microscopic study, J. Nat. Toxins, 1, 45 Johnson, 1993, Isolation of a hemorrhagic toxin from the venom of Agkistrodon contortrix laticinctus (broad-banded copperhead) and pathogenesis of the hemorrhage induced by the toxin in mice, Int. J. Biochem., 25, 267, 10.1016/0020-711X(93)90016-8 Moreira, 1994, Pathological changes induced by BaH1, a hemorrhagic proteinase isolated from Bothrops asper (terciopelo) snake venom, on mouse capillary blood vessels, Toxicon, 32, 977, 10.1016/0041-0101(94)90376-X Lomonte, 1994, The dynamics of local tissue damage induced by Bothrops asper snake venom and myotoxin II on the mouse cremaster muscle: an intravital and electron microscopic study, Toxicon, 32, 41, 10.1016/0041-0101(94)90020-5 Rucavado, 1995, Local tissue damage induced by BaP1, a metalloproteinase isolated from Bothrops asper (terciopelo) snake venom, Exp. Mol. Pathol., 63, 186, 10.1006/exmp.1995.1042 Rucavado, 1999, Characterization of the local tissue damage induced by LHF-II, a metalloproteinase with weak hemorrhagic activity isolated from Lachesis muta muta snake venom, Toxicon, 37, 1297, 10.1016/S0041-0101(98)00268-2 Ohsaka, 1975, The spurting of erythrocytes through junctions of the vascular endothelium treated with snake venom, Microvasc. Res., 10, 208, 10.1016/0026-2862(75)90007-2 Ohsaka, 1979, Hemorrhagic, necrotizing and edema-forming effects of snake venoms, 480, 10.1007/978-3-642-66913-2_14 Collins, 1999, Acute and chronic inflammation, 50 Malucelli, 1980, The haemorrhagic exudate and its possible relationship to neurogenic inflammation, J. Pathol., 130, 193, 10.1002/path.1711300308 Lomonte, 1994, Activity of hemorrhagic metalloproteinase BaH-1 and myotoxin II from Bothrops asper snake venom on capillary endothelial cells in vitro, Toxicon, 32, 505, 10.1016/0041-0101(94)90302-6 Borkow, 1995, In vitro activity of BaH-1, the main hemorhagic toxin of Bothrops asper snake venom on bovine endothelial cells, Toxicon, 32, 1387, 10.1016/0041-0101(95)00078-Z Obrig, 1993, Direct cytotoxic effects of hemorrhagic toxins from Crotalus ruber ruber and Crotalus atrox on human vascular endothelial cells, in vitro, Microvasc. Res., 46, 412, 10.1006/mvre.1993.1065 Marsh, 1995, Isolation and characterisation of two haemorrhagic proteins (HTa and HTb) from the venom of Bitis gabonica (Gaboon viper), Toxicon, 33, 883, 10.1016/0041-0101(95)00029-L Masuda, 1997, Purification of a vascular apoptosis-inducing factor from hemorrhagic snake venom, Biochem. Biophys. Res. Commun., 235, 59, 10.1006/bbrc.1997.6728 Masuda, 1998, Two vascular apoptosis-inducing proteins from snake venom are members of the metalloprotease/disintegrin family, Eur. J. Biochem., 253, 36, 10.1046/j.1432-1327.1998.2530036.x Lukashev, 1998, ECM signalling: orchestrating cell behaviour and misbehaviour, Trends Cell Biol., 8, 437, 10.1016/S0962-8924(98)01362-2 Martin, 1987, Laminin and other basement membrane components, Annu. Rev. Cell Biol., 3, 57, 10.1146/annurev.cb.03.110187.000421 Ohsaka, 1973, Action of snake venom hemorrhagic principles on isolated glomerular basement membrane, Biochim. Biophys. Acta, 323, 415, 10.1016/0005-2736(73)90187-9 Bjarnason, 1988, Studies on the mechanism of hemorrhage production by five proteolytic hemorrhagic toxins from Crotalus atrox venom, Biol. Chem. Hoppe-Seyler, 369, 121 Baramova, 1989, Degradation of extracellular matrix proteins by hemorrhagic metalloproteinases, Arch. Biochem. Biophys., 275, 63, 10.1016/0003-9861(89)90350-0 Baramova, 1990, Identification of the cleavage sites by a hemorrhagic metalloproteinase in type IV collagen, Matrix, 10, 91, 10.1016/S0934-8832(11)80175-7 Baramova, 1991, Proteolytic digestion of non-collagenous basement membrane proteins by the hemorrhagic metallopropteinase Ht-e from Crotalus atrox venom, Biomed. Biochim. Acta, 4–6, 763 Maruyama, 1992, Broad substrate specificity of snake venom fibrinolytic enzymes: possible role in haemorrhage, Toxicon, 30, 1387, 10.1016/0041-0101(92)90514-6 Shapiro, 1998, Matrix metalloproteinase degradation of extracellular matrix: biological consequences, Curr. Opin. Cell Biol., 10, 602, 10.1016/S0955-0674(98)80035-5 Mashiko, 1998, Haemorrhagic factors from snake venoms. II. Structures of haemorrhagic factors and types and mechanisms of haemorrhage, J. Toxicol.-Toxin Rev., 17, 493, 10.3109/15569549809040406 Ballerman, 1998, Shear stress and the endothelium, Kidney Int., 54, S100, 10.1046/j.1523-1755.1998.06720.x Topper, 1999, Blood flow and vascular gene expression: fluid shear stress as a modulator of endothelial phenotype, Mol. Med. Today, 5, 40, 10.1016/S1357-4310(98)01372-0 Moreira, 1992, Ultrastructural alterations in mouse capillary blood vessels after experimental injection of venom from the snake Bothrops asper (terciopelo), Exp. Mol. Pathol., 57, 124, 10.1016/0014-4800(92)90004-U Usami, 1994, A 28 kDa protein with disintegrin-like structure (jararhagin–C) purified from Bothrops jararaca venom inhibits collagen and ADP-induced platelet aggregation, Biochim. Biophys. Res. Commun., 201, 331, 10.1006/bbrc.1994.1706 Shimokawa, 1997, Sequence and biological activity of catrocollastatin-C: a disintegrin-like/cysteine-rich two-domain protein from Crotalus atrox venom, Arch. Biochem. Biophys., 343, 35, 10.1006/abbi.1997.0133 Jia, 1997, Function of disintegrin-like/cysteine-rich domains of atrolysin A. Inhibition of platelet aggregation by recombinant protein and peptide antagonists, J. Biol. Chem., 272, 13094, 10.1074/jbc.272.20.13094 Moura da Silva, 1999, Jararhagin ECD-disintegrin domain: expression in Escherichia coli and inhibition of the platelet-collagen interaction, Arch. Biochem. Biophys., 369, 295, 10.1006/abbi.1999.1372 Kamiguti, 1996, Inhibition of collagen-induced platelet aggregation as the result of cleavage of α2β1-integrin by the snake venom metalloproteinase jararhagin, Biochem. J., 320, 635, 10.1042/bj3200635 Takeya, 1990, Primary structure of a hemorrhagic metalloproteinase, HT-2, isolated from the venom of Crotalus ruber ruber, J. Biochem., 108, 711, 10.1093/oxfordjournals.jbchem.a123270 Zhou, 1995, Molecular cloning and expression of catrocollastatin, a snake venom protein from Crotalus atrox (Western diamondback rattlesnake) which inhibits platelet adhesion to collagen, Biochem J., 307, 411, 10.1042/bj3070411 Jeon, 1999, Molecular cloning and functional characterization of a snake venom metalloprotease, Eur. J. Biochem., 263, 526, 10.1046/j.1432-1327.1999.00525.x Fabiano, 1981, Purification and biochemical study of viriditoxin, tissue damaging toxin, from prairie rattlesnake venom, Biochemistry, 20, 21, 10.1021/bi00504a004 Queiroz, 1985, Pathological changes in muscle caused by haemorrhagic and proteolytic factors from Bothrops jararaca snake venom, Toxicon, 23, 341, 10.1016/0041-0101(85)90158-8 Nikai, 1991, Isolation and characterization of hemorrhagic toxin from the venom of Trimeresurus elegans, Int. J. Biochem., 23, 73, 10.1016/0020-711X(91)90011-B Franceschi, 2000, Purification and characterization of BaH4, a hemorrhagic metalloproteinase from the venom of the snake Bothrops asper, Toxicon, 38, 63, 10.1016/S0041-0101(99)00127-0 Karpati, 1974, Experimental ischemic myopathy, J. Neurol. Sci., 23, 129, 10.1016/0022-510X(74)90148-8 Gutiérrez, 1984, Pathogenesis of myonecrosis induced by crude venom and a myotoxin of Bothrops asper, Exp. Mol. Pathol., 40, 367, 10.1016/0014-4800(84)90054-6 Allbrook, 1981, Skeletal muscle regeneration, Muscle Nerve, 4, 234, 10.1002/mus.880040311 Grounds, 1991, Towards understanding skeletal muscle regeneration, Pathol. Res. Pract., 187, 1, 10.1016/S0344-0338(11)81039-3 Gutiérrez, 1984, Skeletal muscle regeneration after myonecrosis induced by crude venom and a myotoxin from the snake Bothrops asper (Fer-de-Lance), Toxicon, 22, 719, 10.1016/0041-0101(84)90155-7 Arce, 1991, Degenerative and regenerative changes in murine skeletal muscle after injection of venom from the snake Bothrops asper: A histochemical and immunocytochemical study, Int. J. Exp. Pathol., 72, 211 Otero, 1992, Accidente ofídico en Antioquia y Chocó. Aspectos clínicos y epidemiológicos, Acta Médica Colombiana, 17, 229 Eady, 1994, Ultrastructural clues to genetic disorders of skin: the dermal-epidermal junction, J. Invest. Dermatol., 103, 13s, 10.1111/1523-1747.ep12398895 Black, 1997, A metalloproteinase disintegrin that releases tumor-necrosis factor-α from cells, Nature, 385, 729, 10.1038/385729a0 Moss, 1997, Cloning of a disintegrin metalloproteinase that processes precursor tumor-necrosis factor-α, Nature, 385, 733, 10.1038/385733a0 Maskos, 1998, Crystal structure of the catalytic domain of tumor necrosis factor-α-converting enzyme, Proc. Natl. Acad. Sci. USA, 95, 3408, 10.1073/pnas.95.7.3408 Warrell, 1992, The global problem of snake bite: its prevention and treatment, 121 Gutiérrez, 1998, Neutralization of local tissue damage induced by Bothrops asper (terciopelo) snake venom, Toxicon, 36, 1529, 10.1016/S0041-0101(98)00145-7 León, 1997, Immunoglobulin G and F(ab’)2polyvalent antivenoms do not differ in their ability to neutralize hemorrhage, edema and myonecrosis induced by Bothrops asper (terciopelo) snake venom, Toxicon, 35, 1627, 10.1016/S0041-0101(97)00034-2 León, 2000, Comparative study on the ability of IgG and Fab sheep antivenoms to neutralize local hemorrhage, edema and myonecrosis induced by Bothrops asper (terciopelo) snake venom, Toxicon, 38, 233, 10.1016/S0041-0101(99)00152-X Brown, 1999, Clinical studies with matrix metalloproteinase inhibitors, APMIS, 107, 174, 10.1111/j.1699-0463.1999.tb01541.x Johnson, 1998, Matrix metalloproteinases, Curr. Opin. Chem. Biol., 2, 466, 10.1016/S1367-5931(98)80122-1 Gutiérrez, 1999, Metalloproteinase inhibitors in snakebite envenomations, Drug Disc. Today, 4, 532, 10.1016/S1359-6446(99)01408-7 Escalante, 2000, Effectiveness of batimastat, a synthetic inhibitor of matrix metalloproteinases, in neutralizing local tissue damage induced by BaP1, a hemorrhagic metalloproteinase from the venom of the snake Bothrops asper, Biochem. Pharmacol., 60, 269, 10.1016/S0006-2952(00)00302-6