Smoking and inflammation: evidence for a synergistic role in chronic disease

Periodontology 2000 - Tập 64 Số 1 - Trang 111-126 - 2014
Annsofi Johannsen, Cristiano Susin1, Anders Gustafsson
1Periodontics

Tóm tắt

AbstractTobacco smoking is the most important preventable risk factor for periodontitis; however, the underlying biological mechanisms responsible for the detrimental effects of smoking on periodontal health remain largely unclear. It is also well established that smoking has a negative impact on several inflammatory diseases, including rheumatoid arthritis, multiple sclerosis and inflammatory bowel disease. The aim of this paper was to review smoking‐related changes in local and systemic host responses with a focus on cellular and molecular effects that could explain a hyperinflammatory response leading to periodontal destruction. Biological mechanisms that may be common to periodontal disease and other chronic inflammatory diseases were also explored, together with gene–smoking interactions. An epidemiologic perspective on the burden of smoking on periodontal health and the potential for smoking cessation is also presented. Tobacco smoking seems to induce changes ranging from decreased leukocyte chemotaxis to decreased production of immunoglobulins. Smoking also seems to cause a stronger inflammatory reaction with an increased release of potentially tissue‐destructive substances (e.g. reactive oxygen species, collagenase, serine proteases and proinflammatory cytokines). These findings support a hypothesis that periodontitis is a hyperinflammatory condition rather than a hypo‐inflammatory condition.

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Tài liệu tham khảo

10.1034/j.1600-0757.2002.290109.x

10.1111/j.1600-0765.1985.tb00839.x

10.1016/j.rmed.2006.09.023

10.1111/j.1600-051X.2005.00788.x

10.1016/j.cca.2006.12.006

10.2105/AJPH.91.2.253

10.1136/bmj.4.5992.313

10.1016/j.jaut.2009.12.003

10.4103/0972-124X.65427

Babusyte A, 2010, The effect of induced sputum and bronchoalveolar lavage fluid from patients with chronic obstructive pulmonary disease on neutrophil migration in vitro, Medicina (Kaunas), 46, 315, 10.3390/medicina46050044

10.1093/cvr/cvr032

10.1111/j.1600-0757.2010.00347.x

10.1093/oxfordjournals.epirev.a017925

10.1038/clpt.1988.107

10.1016/j.jebdp.2005.12.018

10.1902/jop.2000.71.8.1338

10.1111/j.1600-051X.2006.00945.x

10.1016/S0002-9149(02)02284-1

Bolin A, 1993, The effect of changed smoking habits on marginal alveolar bone loss. A longitudinal study, Swed Dent J, 17, 211

10.1111/j.1600-051X.2005.00799.x

10.1034/j.1600-051x.2001.028003212.x

10.1111/j.1600-051X.1998.tb02368.x

10.1034/j.1600-051X.1999.260604.x

10.1034/j.1600-051x.2000.027004250.x

10.1186/1465-9921-11-99

10.1111/j.1600-051X.2008.01310.x

10.1111/j.1600-051X.2009.01430.x

Burrows B, 1981, The relationship of serum immunoglobulin E to cigarette smoking, Am Rev Respir Dis, 124, 523

10.1164/rccm.200909-1338OC

10.1111/j.1600-051X.2010.01587.x

10.14219/jada.archive.2009.0158

10.1111/j.1600-0757.2006.00178.x

10.1016/S0195-668X(03)00114-3

10.1128/iai.30.3.649-655.1980

10.1053/gast.2001.23231

10.1002/art.20049

10.1111/j.1600-051X.2001.281208.x

10.1182/blood-2007-12-077917

10.1034/j.1600-051x.2000.027006417.x

10.1128/JCM.01821-09

10.1111/j.1600-051X.2008.01223.x

10.1126/science.166.3911.1424

10.1080/14622200110050510

10.1016/j.atherosclerosis.2009.01.007

10.1001/jama.1990.03450020070029

10.1016/S0140-6736(02)11403-6

10.1111/j.1600-051X.2005.00845.x

10.1902/jop.1999.70.11.1355

10.1177/0022034509338676

10.1111/j.1600-0528.1999.tb01987.x

Gerrard JW, 1980, Immunoglobulin levels in smokers and non‐smokers, Ann Allergy, 44, 261

10.1902/jop.2006.060026

10.1177/00220345960750021001

10.1111/j.1600-051X.2004.00522.x

10.1111/j.1600-0765.2005.00852.x

10.1016/j.rmed.2003.08.012

10.1034/j.1600-051x.2001.028005377.x

10.1371/journal.pone.0016149

10.1111/j.1600-051X.2006.00902.x

10.1212/WNL.0b013e3181b59c40

10.1093/brain/awq371

10.1111/j.1600-051X.2008.01275.x

10.1177/0022034510381903

10.1007/BF02247429

10.1034/j.1600-051X.2003.00157.x

10.1902/jop.1999.70.5.518

10.1034/j.1600-051X.2002.290812.x

10.1016/0091-6749(92)90075-D

10.1902/jop.1996.67.7.675

10.1111/j.1600-051X.2004.00585.x

10.3748/wjg.v13.i15.2150

10.1136/ard.2008.102962

10.1111/j.1600-0765.1977.tb00126.x

10.1177/10454411000110030501

10.1136/ard.2010.142109

10.1111/j.1600-051X.1997.tb01187.x

10.1111/j.1600-0765.1977.tb00128.x

10.1111/j.1600-0757.2004.03793.x

10.1016/S0092-8674(00)81569-X

10.3748/wjg.v13.i46.6134

10.1136/thx.2005.040519

10.1111/j.1600-051X.2007.01048.x

10.1161/ATVBAHA.109.199661

10.1016/j.bbadis.2006.05.014

10.1902/jop.2005.76.11-S.2106

10.1902/jop.2004.75.4.557

10.1161/01.ATV.21.4.603

10.1093/aje/kwq088

10.4065/81.11.1462

10.1111/j.1600-051X.2010.01676.x

10.1093/eurheartj/ehq448

10.1902/jop.1999.70.1.49

10.1902/jop.2004.75.2.236

10.1902/jop.2000.71.11.1699

10.1902/jop.2010.100549

10.1111/j.1600-051X.2006.01005.x

10.1034/j.1600-0765.2001.036004227.x

10.1111/j.1600-051X.2004.00476.x

10.1111/j.1600-051X.2004.00612.x

10.1007/s11064-006-9144-5

10.1016/S0378-4274(00)00270-8

10.1902/annals.2003.8.1.266

10.1111/j.1600-051X.2008.01298.x

10.1902/jop.2008.080149

10.1111/j.1600-051X.2006.00982.x

Noble RC, 1975, Comparison of leukocyte count and function in smoking and nonsmoking young men, Infect Immun, 12, 550, 10.1128/iai.12.3.550-555.1975

10.1902/jop.2000.71.9.1460

10.1034/j.1600-0765.2001.360603.x

10.2188/jea.7.205

10.1111/j.1601-0825.2010.01705.x

10.1111/j.1601-0825.2010.01721.x

10.1111/j.1834-7819.2010.01261.x

10.1111/j.1600-0757.1997.tb00189.x

10.1111/j.1600-051X.1993.tb00388.x

10.1111/j.1600-051X.2005.00786.x

10.2105/AJPH.84.7.1086

10.1111/j.1600-051X.2004.00514.x

10.1902/jop.1993.64.7.658

Petrescu F, 2010, Tumor necrosis factor‐alpha serum levels in healthy smokers and nonsmokers, Int J Chron Obstruct Pulmon Dis, 5, 217

10.1111/j.1600-051x.2004.00489.x

10.1111/j.1600-051X.1992.tb01716.x

10.1136/bmj.316.7137.1043

10.1111/j.1600-051X.2005.00779.x

10.1016/0891-5849(92)90040-N

10.1128/iai.64.7.2500-2505.1996

10.1136/thorax.56.6.445

10.1034/j.1600-051X.2003.300107.x

10.1378/chest.08-2288

10.1902/jop.1990.61.7.438

Rolandsson M, 2005, Effects of snuff on the oral health status of adolescent males: a comparative study, Oral Health Prev Dent, 3, 77

10.1056/NEJM199901143400207

10.1111/j.1600-0757.2006.00163.x

10.1111/j.1600-0757.2009.00327.x

10.1111/j.1600-0765.1998.tb02331.x

10.1034/j.1399-302X.2002.170601.x

10.1034/j.1600-051X.2001.280801.x

Sela S, 2002, The involvement of peripheral polymorphonuclear leukocytes in the oxidative stress and inflammation among cigarette smokers, Isr Med Assoc J, 4, 1015

10.1007/BF01534553

Services USDoHaH, 2010, How tobacco smoke causes disease: the biology and behavioral basis for smoking‐attributable disease: a report of the Surgeon General

10.1089/ars.2009.2591

10.1111/j.1750-3639.1999.tb00212.x

10.1016/S0021-9150(03)00200-4

10.1080/000163599428940

10.1034/j.1600-051X.2002.290502.x

10.1016/j.surg.2004.04.001

10.1111/j.1600-0757.2010.00340.x

10.1111/j.1600-051X.2007.01189.x

10.1136/ard.62.9.835

10.1902/jop.1993.64.12.1225

10.1136/ard.2008.096487

10.1111/j.1600-051X.2011.01699.x

10.1111/j.1600-051x.2004.00588.x

10.1152/ajpheart.00868.2010

10.1902/jop.1997.68.9.842

10.1111/j.1600-051X.2007.01131.x

10.1902/jop.1995.66.12.1056

10.1902/jop.2000.71.5.743

10.1111/j.1600-051X.2009.01485.x

10.1111/j.1600-051X.2010.01684.x

10.1038/nrd1797

10.1902/jop.1998.69.10.1111

10.1016/j.crohns.2009.09.005

10.1034/j.1600-051X.2003.00080.x

10.1902/jop.1986.57.11.703

10.1902/jop.2001.72.5.666

10.1111/j.1600-051X.2010.01592.x

10.1093/eurheartj/ehi183

10.1016/j.oraloncology.2008.06.002

10.1922/IDJ_2532Warnakulasuriya24

WHO, 2008, Report on the global tobacco epidemic: the MPOWER package

Witherick J, 2010, Mechanisms of oxidative damage in multiple sclerosis and a cell therapy approach to treatment, Autoimmune Dis, 2011, 164608

10.1902/jop.2004.75.4.517

10.1111/j.1600-051X.2005.00819.x

10.1378/chest.06-2179

10.1902/jop.1996.67.10s.1050

10.1002/bio.1233

10.1902/jop.2010.100540