Smart nanocarriers for cancer treatment: Clinical impact and safety

Acharya, 2011, PLGA nanoparticles containing various anticancer agents and tumour delivery by EPR effect, Adv. Drug Deliv. Rev., 63, 170, 10.1016/j.addr.2010.10.008 Ahuja, 2017, Nanoparticle Drug Delivery for Cancer Therapy: An Update, SF Drug Deliv Res J, 1(2) Akbarzadeh, 2013, Liposome: classification, preparation, and applications, Nanoscale Res. Lett., 8, 102, 10.1186/1556-276X-8-102 Alam, 2015, Unique roles of nanotechnology in medicine and cancer-II, Indian J. Cancer, 52, 1, 10.4103/0019-509X.175591 Alavi, 2019, Passive and active targeting in cancer therapy by liposomes and lipid nanoparticles, Drug metabolism and personalized therapy, 34(1) Amin, 2017, Chapter 5 - Polymeric Micelles for Drug Targeting and Delivery, 167 Bahrami, 2017, Nanoparticles and targeted drug delivery in cancer therapy.(Report), Immunol. Lett., 190, 64, 10.1016/j.imlet.2017.07.015 Bamrungsap, 2012, Nanotechnology in therapeutics: a focus on nanoparticles as a drug delivery system, Nanomedicine, 7, 1253, 10.2217/nnm.12.87 Basha, 2019, Liposomes in Active, Passive and Acoustically-Triggered Drug Delivery, Mini-Rev. Med. Chem., 19, 961, 10.2174/1389557519666190408155251 Beltrán-Gracia, 2019, Nanomedicine review: clinical developments in liposomal applications, Cancer Nanotechnology, 10, 11, 10.1186/s12645-019-0055-y Bosetti, 2015, Cost–effectiveness of nanomedicine: the path to a future successful and dominant market?, Nanomedicine, 10, 1851, 10.2217/nnm.15.74 Brannon-Peppas, 2012, Nanoparticle and targeted systems for cancer therapy, Adv. Drug Deliv. Rev., 64, 206, 10.1016/j.addr.2012.09.033 Bray, 2018, Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries, CA, 68, 394 Brigger, 2012, Nanoparticles in cancer therapy and diagnosis, Adv. Drug Deliv. Rev., 64, 24, 10.1016/j.addr.2012.09.006 Cabral, 2018, Block copolymer micelles in nanomedicine applications, Chem. Rev., 118, 6844, 10.1021/acs.chemrev.8b00199 Cameron, 2016, Vascular Complications of Cancer Chemotherapy, Can. J. Cardiol., 32, 852, 10.1016/j.cjca.2015.12.023 Chauhan, 2018, Dendrimers for drug delivery, Molecules, 23, 938, 10.3390/molecules23040938 Chen, 2017, The advances of carbon nanotubes in cancer diagnostics and therapeutics, J. Nanomater., 2017, 10.1155/2017/3418932 Chenthamara, 2019, Therapeutic efficacy of nanoparticles and routes of administration, Biomaterials Research, 23, 1, 10.1186/s40824-019-0166-x Chidambaram, 2011, Nanotherapeutics to overcome conventional cancer chemotherapy limitations, J. Pharm. Pharm. Sci., 14, 67, 10.18433/J30C7D Cho, 2008, Therapeutic nanoparticles for drug delivery in cancer, Clin. Cancer Res., 14, 1310, 10.1158/1078-0432.CCR-07-1441 Costa, 2016, Functionalised carbon nanotubes: From intracellular uptake and cell-related toxicity to systemic brain delivery, J. Control. Release, 241, 200, 10.1016/j.jconrel.2016.09.033 Crain, 2018, Daunorubicin & Cytarabine liposome (vyxeos™), Oncology Times, 40, 30, 10.1097/01.COT.0000534146.30839.ec Cryer, 2019, Nanotechnology in the diagnosis and treatment of lung cancer.(Report), Pharmacol. Ther., 198, 189, 10.1016/j.pharmthera.2019.02.010 Das, 2009, Ligand-based targeted therapy for cancer tissue, Exp. Opini. Drug Deliv., 6, 285, 10.1517/17425240902780166 Deshpande, 2018, Transferrin and octaarginine modified dual-functional liposomes with improved cancer cell targeting and enhanced intracellular delivery for the treatment of ovarian cancer, Drug delivery, 25, 517, 10.1080/10717544.2018.1435747 Evans, 2018, Metallic nanoparticles for cancer immunotherapy, Mater. Today, 21, 673, 10.1016/j.mattod.2017.11.022 Fan, 2013, Development of liposomal formulations: From concept to clinical investigations, Asian J. Pharm. Sci., 8, 81, 10.1016/j.ajps.2013.07.010 Fukuda, 2017, Comparison of the adverse event profiles of conventional and liposomal formulations of doxorubicin using the FDA adverse event reporting system, PLoS One, 12(9) Gurunathan, 2018, Nanoparticle-mediated combination therapy: Two-in-one approach for cancer, Int. J. Mol. Sci., 19, 3264, 10.3390/ijms19103264 Halamoda-Kenzaoui, 2017, The agglomeration state of nanoparticles can influence the mechanism of their cellular internalisation, Journal of nanobiotechnology, 15, 1, 10.1186/s12951-017-0281-6 Haley, 2008, Nanoparticles for drug delivery in cancer treatment, Urologic Oncology: Seminars and Original Investigations, 26, 57, 10.1016/j.urolonc.2007.03.015 Hasnain, M.S., Carbon Nanotubes for Targeted Drug Delivery. 1st ed. 2019. ed. SpringerBriefs in Applied Sciences and Technology, ed. A.K. Nayak. 2019, Singapore: Springer Singapore. Ho, 2017, Update on nanotechnology-based drug delivery systems in cancer treatment, Anticancer Res., 37, 5975 Hossen, 2019, Smart nanocarrier-based drug delivery systems for cancer therapy and toxicity studies: A review, J. Adv. Res., 15, 1, 10.1016/j.jare.2018.06.005 Huang, 2017, A review on the effects of current chemotherapy drugs and natural agents in treating non–small cell lung cancer, Biomedicine, 7(4) Huang, 2017, Current applications and future prospects of nanomaterials in tumor therapy, Int. J. Nanomedicine, 12, 1815, 10.2147/IJN.S127349 Kalaydina, 2018, Recent advances in “smart” delivery systems for extended drug release in cancer therapy, Int. J. Nanomedicine, 13, 4727, 10.2147/IJN.S168053 Kamimura, 2014, Chapter 14 - PEGylated polymer micelles for anticancer drug delivery carrier, 285 Kaur, 2017, Development and characterization of surface engineered PPI dendrimers for targeted drug delivery, Artificial cells, nanomedicine, and biotechnology, 45, 414, 10.3109/21691401.2016.1160912 Kavosi, 2018, The toxicity and therapeutic effects of single-and multi-wall carbon nanotubes on mice breast cancer, Sci. Rep., 8, 1, 10.1038/s41598-018-26790-x Kesharwani, 2019, Multifunctional approaches utilizing polymeric micelles to circumvent multidrug resistant tumors, Colloids Surf. B: Biointerfaces, 173, 581, 10.1016/j.colsurfb.2018.10.022 Khan, 2019, Nanoparticles: Properties, applications and toxicities, Arab. J. Chem., 12, 908, 10.1016/j.arabjc.2017.05.011 Kim, 2017, Multicenter phase II clinical trial of Genexol-PM® with gemcitabine in advanced biliary tract cancer, Anticancer Res., 37, 1467, 10.21873/anticanres.11471 Kim, 2018, Recent progress in dendrimer-based nanomedicine development.(Report), Arch. Pharm. Res., 41, 571, 10.1007/s12272-018-1008-4 Kumar, 2020, Emerging Nanomaterials for Cancer Therapy, 25-54 Le, 2017, Multi-drug loaded micelles delivering chemotherapy and targeted therapies directed against HSP90 and the PI3K/AKT/mTOR pathway in prostate cancer, PLoS One, 12(3) Li, 2018, Poly (amidoamine) (PAMAM) dendrimer mediated delivery of drug and pDNA/siRNA for cancer therapy.(Report), Int. J. Pharm., 546, 215, 10.1016/j.ijpharm.2018.05.045 Li, 2018, Co-delivery of drugs and genes using polymeric nanoparticles for synergistic cancer therapeutic effects, Advanced Healthcare Materials, 7, 1700886, 10.1002/adhm.201700886 Li, 2017, Cancer drug delivery in the nano era: An overview and perspectives (review), Oncol. Rep., 38, 611, 10.3892/or.2017.5718 Liao, 2019, Reactive oxygen species: a volatile driver of field cancerization and metastasis, Mol. Cancer, 18, 1, 10.1186/s12943-019-0961-y Liao, 2019, Cancer-associated fibroblasts in tumor microenvironment–Accomplices in tumor malignancy, Cell. Immunol., 343, 103729, 10.1016/j.cellimm.2017.12.003 Lin, 2018, Dual-ligand modified liposomes provide effective local targeted delivery of lung-cancer drug by antibody and tumor lineage-homing cell-penetrating peptide, Drug Delivery, 25, 256, 10.1080/10717544.2018.1425777 Lombardo, 2019, Smart nanoparticles for drug delivery application: development of versatile nanocarrier platforms in biotechnology and nanomedicine, J. Nanomater., 2019, 10.1155/2019/3702518 Madani, 2011, A new era of cancer treatment: carbon nanotubes as drug delivery tools, Int. J. Nanomedicine, 6, 2963 Mahapatro, 2011, Biodegradable nanoparticles are excellent vehicle for site directed in-vivo delivery of drugs and vaccines, Journal of nanobiotechnology, 9, 55, 10.1186/1477-3155-9-55 Mahjub, 2018, Recent advances in applying nanotechnologies for cancer immunotherapy.(Report), J. Control. Release, 288, 239, 10.1016/j.jconrel.2018.09.010 Malam, 2009, Liposomes and nanoparticles: nanosized vehicles for drug delivery in cancer, Trends Pharmacol. Sci., 30, 592, 10.1016/j.tips.2009.08.004 Miller, 2016, Cancer treatment and survivorship statistics, 2016, CA Cancer J. Clin., 66, 271, 10.3322/caac.21349 Mir, 2017, Nanotechnology: from in vivo imaging system to controlled drug delivery, Nanoscale Res. Lett., 12, 500, 10.1186/s11671-017-2249-8 Mishra, 2016, PEGylation in anti-cancer therapy: An overview, Asian J. Pharm. Sci., 11, 337, 10.1016/j.ajps.2015.08.011 Mülhopt, 2018, Characterization of nanoparticle batch-to-batch variability, Nanomaterials, 8, 311, 10.3390/nano8050311 Navya, 2019, Current trends and challenges in cancer management and therapy using designer nanomaterials, Nano convergence, 6, 23, 10.1186/s40580-019-0193-2 Palmerston Mendes, 2017, Dendrimers as nanocarriers for nucleic acid and drug delivery in cancer therapy, Molecules, 22, 1401, 10.3390/molecules22091401 Pan, 2019, Polymeric co-delivery systems in cancer treatment: An overview on component drugs’ dosage ratio effect, Molecules, 24, 1035, 10.3390/molecules24061035 Parhi, 2012, Nanotechnology-based combinational drug delivery: an emerging approach for cancer therapy, Drug Discov. Today, 17, 1044, 10.1016/j.drudis.2012.05.010 Patra, 2018, Nano based drug delivery systems: recent developments and future prospects, Journal of nanobiotechnology, 16, 71, 10.1186/s12951-018-0392-8 Pillai, 2013, Science and technology of the emerging nanomedicines in cancer therapy: A primer for physicians and pharmacists, SAGE open medicine, 1, 10.1177/2050312113513759 Poonia, 2017, Nanotechnology in oral cancer: A comprehensive review, Journal of oral and maxillofacial pathology: JOMFP, 21, 407, 10.4103/jomfp.JOMFP_29_17 Pushpalatha, 2017, Nanocarrier mediated combination drug delivery for chemotherapy - A review, J. Drug Deliv. Sci. Technol., 39, 362, 10.1016/j.jddst.2017.04.019 Qin, 2017, Nanomaterials in targeting cancer stem cells for cancer therapy, Front. Pharmacol., 8, 1, 10.3389/fphar.2017.00001 Riaz, 2018, Surface functionalization and targeting strategies of liposomes in solid tumor therapy: A review, Int. J. Mol. Sci., 19, 195, 10.3390/ijms19010195 Rizvi, 2018, Applications of nanoparticle systems in drug delivery technology, Saudi Pharmaceutical Journal, 26, 64, 10.1016/j.jsps.2017.10.012 Saikia, N., Functionalized Carbon Nanomaterials in Drug Delivery: Emergent Perspectives from Application, in Novel Nanomaterials-Synthesis and Applications. 2017, IntechOpen. Sanginario, 2017, Carbon nanotubes as an effective opportunity for cancer diagnosis and treatment, Biosensors, 7, 9, 10.3390/bios7010009 Sarkar, 2017, Advances and implications in nanotechnology for lung cancer management, Curr. Drug Metab., 18, 30, 10.2174/1389200218666161114142646 Sathiyajith, 2017, Nanovaccines for cancer immunotherapy, International Journal of Vaccines & Vaccination, 4(4) Senapati, 2018, Controlled drug delivery vehicles for cancer treatment and their performance, Signal transduction and targeted therapy, 3, 1, 10.1038/s41392-017-0004-3 Sengel-Turk, 2017, Chapter 10 - Nanosized Drug Carriers for Oral Delivery of Anticancer Compounds and the Importance of the Chromatographic Techniques, 165 Sercombe, 2015, Advances and challenges of liposome assisted drug delivery, Front. Pharmacol., 6, 286, 10.3389/fphar.2015.00286 Shadrack, 2018, Polyamidoamine dendrimers for enhanced solubility of small molecules and other desirable properties for site specific delivery: Insights from experimental and computational studies, Molecules, 23, 1419, 10.3390/molecules23061419 Simon, 2019, Overview of carbon nanotubes for biomedical applications, Materials, 12, 624, 10.3390/ma12040624 Singh, 2009, Nanoparticle-based targeted drug delivery, Exp. Mol. Pathol., 86, 215, 10.1016/j.yexmp.2008.12.004 Sofias, 2017, The battle of “nano” paclitaxel, Adv. Drug Deliv. Rev., 122, 20, 10.1016/j.addr.2017.02.003 Song, G., et al., Emerging Nanotechnology and Advanced Materials for Cancer Radiation Therapy.(Report). 2017, Wiley Subscription Services, Inc. p. n/a. Stefanick, 2019, Dual-receptor targeted strategy in nanoparticle design achieves tumor cell selectivity through cooperativity, Nanoscale, 11, 4414, 10.1039/C8NR09431D Steichen, 2013, A review of current nanoparticle and targeting moieties for the delivery of cancer therapeutics, Eur. J. Pharm. Sci., 48, 416, 10.1016/j.ejps.2012.12.006 Su, 2018, Potential applications and human biosafety of nanomaterials used in nanomedicine, J. Appl. Toxicol., 38, 3, 10.1002/jat.3476 Suk, 2016, PEGylation as a strategy for improving nanoparticle-based drug and gene delivery, Adv. Drug Deliv. Rev., 99, 28, 10.1016/j.addr.2015.09.012 Sun, 2014, Engineered Nanoparticles for Drug Delivery in Cancer Therapy, WILEY-VCH Verlag: Weinheim. p., 12320-12364 Tran, 2017, Cancer nanomedicine: a review of recent success in drug delivery, Clin. Transl. Med., 6, 44, 10.1186/s40169-017-0175-0 Ud Din, 2017, Effective use of nanocarriers as drug delivery systems for the treatment of selected tumors, Int. J. Nanomedicine, 12, 7291, 10.2147/IJN.S146315 Van Norman, 2016, Drugs, Devices, and the FDA: Part 1, JACC: Basic to Translational Science, 1, 170 Varela-Moreira, 2017, Clinical application of polymeric micelles for the treatment of cancer, Materials Chemistry Frontiers, 1, 1485, 10.1039/C6QM00289G Vasir, 2005, Targeted drug delivery in cancer therapy, Technology in cancer research & treatment, 4, 363, 10.1177/153303460500400405 Ventola, 2017, Progress in nanomedicine: approved and investigational nanodrugs, Pharmacy and Therapeutics, 42, 742 Wakaskar, 2017, Passive and active targeting in tumor microenvironment, International journal of drug development and research, 9, 37 Xin, 2017, Recent progress on nanoparticle-based drug delivery systems for cancer therapy, Cancer Biol. & Med., 14, 228, 10.20892/j.issn.2095-3941.2017.0052 Xiong, 2018, Dendrimer-based strategies for cancer therapy: Recent advances and future perspectives, Science China Materials, 61, 1387, 10.1007/s40843-018-9271-4 Yu, 2019, Intelligent polymeric micelles for multidrug co-delivery and cancer therapy, Artificial cells, nanomedicine, and biotechnology, 47, 1476, 10.1080/21691401.2019.1601104 Zhou, 2018, Stimuli-responsive polymeric micelles for drug delivery and cancer therapy, Int. J. Nanomedicine, 13, 2921, 10.2147/IJN.S158696 Zottel, 2019, Nanotechnology meets oncology: Nanomaterials in brain cancer research, diagnosis and therapy, Materials, 12, 1588, 10.3390/ma12101588