Smart medication through combination of synthetic biology and cell microencapsulation

Abalovich, 2009, Pig pancreatic islet transplantation into spontaneously diabetic dogs, Transplant. Proc., 41, 328, 10.1016/j.transproceed.2008.08.159 Ascoli, 2002, The lutropin/choriogonadotropin receptor, a 2002 perspective, Endocr. Rev., 23, 141, 10.1210/er.23.2.141 Bachoud-Levi, 2000, Neuroprotective gene therapy for Huntington's disease using a polymer encapsulated BHK cell line engineered to secrete human CNTF, Hum. Gene Ther., 11, 1723, 10.1089/10430340050111377 Balch, 2008, Adapting proteostasis for disease intervention, Science, 319, 916, 10.1126/science.1141448 Berens, 2003, Gene regulation by tetracyclines—constraints of resistance regulation in bacteria shape TetR for application in eukaryotes, Eur. J. Biochem., 270, 3109, 10.1046/j.1432-1033.2003.03694.x Blancafort, 2004, Designing transcription factor architectures for drug discovery, Mol. Pharmacol., 66, 1361, 10.1124/mol.104.002758 Blanco-Bose, 2006, Inducing tolerance to a soluble foreign antigen by encapsulated cell transplants, Mol. Ther., 13, 447, 10.1016/j.ymthe.2005.08.010 Bloch, 2004, Neuroprotective gene therapy for Huntington's disease, using polymer-encapsulated cells engineered to secrete human ciliary neurotrophic factor: results of a phase I study, Hum. Gene Ther., 15, 968, 10.1089/hum.2004.15.968 Calafiore, 1999, Transplantation of pancreatic islets contained in minimal volume microcapsules in diabetic high mammalians, Bioartif. Organs II: Technol. Med. Mater., 875, 219 Cameron, 2007, Uric acid nephrolithiasis, Urol. Clin. North Am., 34, 335, 10.1016/j.ucl.2007.05.001 Catena, 2010, Improvement of the monitoring and biosafety of encapsulated cells using the SFGNESTGL triple reporter system, J. Control Release, 146, 93, 10.1016/j.jconrel.2010.05.018 Chang, 1964, Semipermeable microcapsules, Science, 146, 524, 10.1126/science.146.3643.524 Chang, 2005, Therapeutic applications of polymeric artificial cells, Nat. Rev. Drug Discovery, 4, 221, 10.1038/nrd1659 Cruise, 1999, In vitro and in vivo performance of porcine islets encapsulated in interfacially photopolymerized poly(ethylene glycol) diacrylate membranes, Cell Transplant., 8, 293, 10.1177/096368979900800310 Culler, 2010, Reprogramming cellular behavior with RNA controllers responsive to endogenous proteins, Science, 330, 1251, 10.1126/science.1192128 Danino, 2010, A synchronized quorum of genetic clocks, Nature, 463, 326, 10.1038/nature08753 Deuschle, 1995, Tetracycline-reversible silencing of eukaryotic promoters, Mol. Cell Biol., 15, 1907, 10.1128/MCB.15.4.1907 Drury, 2003, Hydrogels for tissue engineering: scaffold design variables and applications, Biomaterials, 24, 4337, 10.1016/S0142-9612(03)00340-5 Dubrot, 2010, Delivery of immunostimulatory monoclonal antibodies by encapsulated hybridoma cells, Cancer Immunol. Immunother., 59, 1621, 10.1007/s00262-010-0888-z Dusseault, 2006, Evaluation of alginate purification methods: effect on polyphenol, endotoxin, and protein contamination, J. Biomed. Mater. Res. A, 76, 243, 10.1002/jbm.a.30541 Duvivier-Kali, 2001, Complete protection of islets against allorejection and autoimmunity by a simple barium-alginate membrane, Diabetes, 50, 1698, 10.2337/diabetes.50.8.1698 Emerich, 1997, Protective effect of encapsulated cells producing neurotrophic factor CNTF in a monkey model of Huntington's disease, Nature, 386, 395, 10.1038/386395a0 Faustini, 2004, Boar spermatozoa encapsulated in barium alginate membranes: a microdensitometric evaluation of some enzymatic activities during storage at 18°C, Theriogenology, 61, 173, 10.1016/S0093-691X(03)00203-6 Fluri, 2008, A novel system for trigger-controlled drug release from polymer capsules, J Control Release, 131, 211, 10.1016/j.jconrel.2008.07.036 Freundlieb, 1999, A tetracycline controlled activation/repression system with increased potential for gene transfer into mammalian cells, J. Gene Med., 1, 4, 10.1002/(SICI)1521-2254(199901/02)1:1<4::AID-JGM4>3.0.CO;2-Y Fussenegger, 2000, Streptogramin-based gene regulation systems for mammalian cells, Nat. Biotechnol., 18, 1203, 10.1038/81208 Gitzinger, 2009, Controlling transgene expression in subcutaneous implants using a skin lotion containing the apple metabolite phloretin, Proc. Natl. Acad. Sci. USA, 106, 10638, 10.1073/pnas.0901501106 Gossen, 1992, Tight control of gene-expression in mammalian-cells by tetracycline-responsive promoters, Proc. Natl. Acad. Sci. USA, 89, 5547, 10.1073/pnas.89.12.5547 Govan, 1981, Isolation of alginate-producing mutants of Pseudomonas fluorescens, Pseudomonas putida and Pseudomonas mendocina, J. Gen. Microbiol., 125, 217 Hartenbach, 2007, An engineered l-arginine sensor of Chlamydia pneumoniae enables arginine-adjustable transcription control in mammalian cells and mice, Nucleic Acids Res., 35, e136, 10.1093/nar/gkm652 Hasse, 1994, Successful allotransplantation of microencapsulated parathyroids in rats, World J. Surg., 18, 630, 10.1007/BF00353783 Hasse, 1997, Isotransplantation of microencapsulated parathyroid tissue in rats, Exp. Clin. Endocrinol. Diabetes, 105, 53, 10.1055/s-0029-1211727 Hernandez, 2010, Microcapsules and microcarriers for in situ cell delivery, Adv. Drug Delivery Rev., 62, 711, 10.1016/j.addr.2010.02.004 Hernandez, 2010, Microcapsules and microcarriers for in situ cell delivery, Adv. Drug Deliv. Rev., 62, 711, 10.1016/j.addr.2010.02.004 Hunder, 2008, Treatment of metastatic melanoma with autologous CD4+ T cells against NY-ESO-1, N. Engl. J. Med., 358, 2698, 10.1056/NEJMoa0800251 Hunt, 2010, Cell encapsulation using biopolymer gels for regenerative medicine, Biotechnol. Lett., 32, 733, 10.1007/s10529-010-0221-0 Husseinzadeh, 2011, Status of tumor markers in epithelial ovarian cancer has there been any progress? A review, Gynecol. Oncol., 120, 152, 10.1016/j.ygyno.2010.09.002 Kawahara, 2010, Neurotoxicity of beta-amyloid protein: oligomerization, channel formation and calcium dyshomeostasis, Curr. Pharm. Des., 16, 2779, 10.2174/138161210793176545 Kemmer, C., Fluri, D.A., Witschi, U., Passeraub, A., Gutzwiller, A., Fussenegger, M., 2010a. A designer network coordinating bovine artificial insemination by ovulation-triggered release of implanted sperms. J. Control Release 150, 23–29 Kemmer, 2010, Self-sufficient control of urate homeostasis in mice by a synthetic circuit, Nat. Biotechnol., 28, 10.1038/nbt.1617 Khalil, 2010, Synthetic biology: applications come of age, Nat. Rev. Genet., 11, 367, 10.1038/nrg2775 Kobayashi, 2006, Control of dopamine-secretion by Tet-Off system in an in vivo model of parkinsonian rat, Brain Res., 1102, 1, 10.1016/j.brainres.2006.04.078 Koo, 1993, Secretion of erythropoietin from microencapsulated rat kidney cells: preliminary results, Int. J. Artif. Organs, 16, 557, 10.1177/039139889301600710 Kramer, 2004, BioLogic gates enable logical transcription control in mammalian cells, Biotechnol. Bioeng., 87, 478, 10.1002/bit.20142 Kutzing, 2008, Altered uric acid levels and disease states, J. Pharmacol. Exp. Ther., 324, 1, 10.1124/jpet.107.129031 Lim, 1980, Microencapsulated islets as bioartificial endocrine pancreas, Science, 210, 908, 10.1126/science.6776628 Ma, 2002, Dyskinesia after fetal cell transplantation for parkinsonism: a PET study, Ann. Neurol., 52, 628, 10.1002/ana.10359 Melero, 2007, Immunostimulatory monoclonal antibodies for cancer therapy, Nat. Rev. Cancer, 7, 95, 10.1038/nrc2051 Morgan, 2006, Cancer regression in patients after transfer of genetically engineered lymphocytes, Science, 314, 126, 10.1126/science.1129003 Mullick, 2006, The cumate gene-switch: a system for regulated expression in mammalian cells, BMC Biotechnol., 6, 43, 10.1186/1472-6750-6-43 Nordstrom, 2002, Antiprogestin-controllable transgene regulation in vivo, Curr. Opin. Biotechnol., 13, 453, 10.1016/S0958-1669(02)00356-7 Okada, 1997, Cytomedical therapy for IgG1 plasmacytosis in human interleukin-6 transgenic mice using hybridoma cells microencapsulated in alginate-poly(l)lysine-alginate membrane, Biochim. Biophys. Acta—Mol. Basis Dis., 1360, 53, 10.1016/S0925-4439(96)00066-X Orive, 2009, Bioactive cell-hydrogel microcapsules for cell-based drug delivery, J. Control Release, 135, 203, 10.1016/j.jconrel.2009.01.005 Orive, 2003, Cell encapsulation: promise and progress, Nat. Med., 9, 104, 10.1038/nm0103-104 Purnick, 2009, The second wave of synthetic biology: from modules to systems, Nat. Rev. Mol. Cell Biol., 10, 410, 10.1038/nrm2698 Ramos, 2005, The TetR family of transcriptional repressors, Microbiol. Mol. Biol. Rev., 69, 326, 10.1128/MMBR.69.2.326-356.2005 Regot, 2011, Distributed biological computation with multicellular engineered networks, Nature, 469, 207, 10.1038/nature09679 Rinaudo, 2007, A universal RNAi-based logic evaluator that operates in mammalian cells, Nat. Biotechnol., 25, 795, 10.1038/nbt1307 Rinaudo, 2007, A universal RNAi-based logic evaluator that operates in mammalian cells, Nat. Biotechnol., 25, 795, 10.1038/nbt1307 Roscilli, 2002, Long-term and tight control of gene expression in mouse skeletal muscle by a new hybrid human transcription factor, Mol. Ther., 6, 653, 10.1016/S1525-0016(02)90717-3 Rowley, 2002, Alginate type and RGD density control myoblast phenotype, J. Biomed. Mater. Res., 60, 217, 10.1002/jbm.1287 Saitoh, 1995, Cell therapy with encapsulated xenogeneic tumor cells secreting beta-endorphin for treatment of peripheral pain, Cell Transplant., 4, S13, 10.1016/0963-6897(94)00072-R Soon-Shiong, 1999, Treatment of type I diabetes using encapsulated islets, Adv. Drug Delivery Rev., 35, 259, 10.1016/S0169-409X(98)00076-3 Soonshiong, 1993, Long-term reversal of diabetes by the injection of immunoprotected islets, Proc. Natl. Acad. Sci. USA, 90, 5843, 10.1073/pnas.90.12.5843 Soonshiong, 1994, Insulin Independence in a type-1 diabetic patient after encapsulated islet transplantation, Lancet, 343, 950, 10.1016/S0140-6736(94)90067-1 Sun, 1996, Normalization of diabetes in spontaneously diabetic cynomologus monkeys by xenografts of microencapsulated porcine islets without immunosuppression, J. Clin. Invest., 98, 1417, 10.1172/JCI118929 Suzuki, 2002, Cytomedical therapy for insulinopenic diabetes using microencapsulated pancreatic beta cell lines, Life Sci., 71, 1717, 10.1016/S0024-3205(02)01724-1 Tabor, 2011, Multichromatic control of gene expression in Escherichia coli, J. Mol. Biol., 405, 315, 10.1016/j.jmb.2010.10.038 Tamsir, 2011, Robust multicellular computing using genetically encoded NOR gates and chemical 'wires', Nature, 469, 212, 10.1038/nature09565 Thorsen, 2000, Alginate-encapsulated producer cells: a potential new approach for the treatment of malignant brain tumors, Cell Transplant., 9, 773, 10.1177/096368970000900604 Tigges, 2010, A synthetic low-frequency mammalian oscillator, Nucleic Acids Res., 38, 2702, 10.1093/nar/gkq121 Tigges, 2009, A tunable synthetic mammalian oscillator, Nature, 457, 309, 10.1038/nature07616 Toettcher, 2010, A synthetic-natural hybrid oscillator in human cells, Proc. Natl. Acad. Sci. USA, 107, 17047, 10.1073/pnas.1005615107 Vigo, 2009, Semen controlled-release capsules allow a single artificial insemination in sows, Theriogenology, 72, 439, 10.1016/j.theriogenology.2009.03.013 Wang, 2006, Microencapsulation using natural polysaccharides for drug delivery and cell implantation, J. Mater. Chem., 16, 3252, 10.1039/b603595g Weber, 2007, Vitamin H-regulated transgene expression in mammalian cells, Nucleic Acids Res., 35, e116, 10.1093/nar/gkm466 Weber, 2007, Synthetic ecosystems based on airborne inter- and intrakingdom communication, Proc. Natl. Acad. Sci. USA, 104, 10435, 10.1073/pnas.0701382104 Weber, 2009, Engineering of synthetic mammalian gene networks, Chem. Biol., 16, 287, 10.1016/j.chembiol.2009.02.005 Weber, 2002, Macrolide-based transgene control in mammalian cells and mice, Nat. Biotechnol., 20, 901, 10.1038/nbt731 Weber, 2009, A biotin-triggered genetic switch in mammalian cells and mice, Metab. Eng., 11, 117, 10.1016/j.ymben.2008.12.001 Weber, 2009, A synthetic mammalian electro-genetic transcription circuit, Nucleic Acids Res., 37, e33, 10.1093/nar/gkp014 Weber, 2006, Design of high-throughput-compatible protocols for microencapsulation, cryopreservation and release of bovine spermatozoa, J. Biotechnol., 123, 155, 10.1016/j.jbiotec.2005.11.008 Weber, 2008, A synthetic mammalian gene circuit reveals antituberculosis compounds, Proc. Natl. Acad. Sci. USA, 105, 9994, 10.1073/pnas.0800663105 Wieland, 2010, Ligand-dependent regulatory RNA parts for synthetic biology in eukaryotes, Curr. Opin. Biotechnol., 21, 760, 10.1016/j.copbio.2010.06.010 Win, 2008, Higher-order cellular information processing with synthetic RNA devices, Science, 322, 456, 10.1126/science.1160311 Wong, 1986, Bioartificial liver: implanted artificial cells microencapsulated living hepatocytes increases survival of liver failure rats, Int. J. Artif. Organs, 9, 335, 10.1177/039139888600900515 Wong, 1988, The viability and regeneration of artificial cell microencapsulated rat hepatocyte xenograft transplants in mice, Biomater. Artif. Cells Artif. Organs, 16, 731, 10.3109/10731198809117565 Wu, 1994, Hyperuricemia and urate nephropathy in urate oxidase-deficient mice, Proc. Natl. Acad. Sci. USA, 91, 742, 10.1073/pnas.91.2.742 Xue, 2008, The cancer secretome: a reservoir of biomarkers, J. Transl. Med., 6, 52, 10.1186/1479-5876-6-52 You, 2004, Programmed population control by cell–cell communication and regulated killing, Nature, 428, 868, 10.1038/nature02491 Zhang, 2011, Efficient construction of sequence-specific TAL effectors for modulating mammalian transcription, Nat. Biotechnol., 29, 149, 10.1038/nbt.1775 Zhang, 2008, Transplantation of microencapsulated genetically modified xenogeneic cells augments angiogenesis and improves heart function, Gene Ther., 15, 40, 10.1038/sj.gt.3303049