Small intestine proteomics coupled with serum metabolomics reveal disruption of amino acid metabolism in Chinese hamsters with type 2 diabetes mellitus

Journal of Proteomics - Tập 223 - Trang 103823 - 2020
Chenyang Wang1, Jingjing Yu1, Ruihu Zhang1, Wentao Wang2, Zeya Shi1, Yu Liu3, Guohua Song1, Hailong Wang2, Nai-Jian Han4, Liqun Huang5, Yuze An2, Shouyuan Tian6, Zhaoyang Chen1
1Labratory Animal Center, Shanxi Key Laboratory of Experimental Animal Science and Animal Model of Human Disease, Shanxi Medical University, Taiyuan 030001, China
2School of Basic Medicine, Shanxi Medical University, Taiyuan 030001, China
3Department of Pharmacology, Shanxi Medical University, Taiyuan, 030001, China
4Jingjie PTM BioLab (Hangzhou) Co. Ltd, No.452, 6th Street Hangzhou Eco.&Tech. Developmental Area, Hangzhou 310018, China
5Department of Radiological and Evironmental Medicine, China Institute of Radiation Protection, Taiyuan 030006, China
6Department of Anesthesiology, First Hospital of Shanxi Medical University, Shanxi Medical University, Taiyuan 030001, China

Tóm tắt

Từ khóa


Tài liệu tham khảo

Burke, 2012, Health care utilization and costs in type 2 diabetes mellitus and their association with renal impairment, Postgrad. Med., 124, 77, 10.3810/pgm.2012.03.2539

Guariguata, 2014, Global estimates of diabetes prevalence for 2013 and projections for 2035, Diabetes Res. Clin. Pract., 103, 137, 10.1016/j.diabres.2013.11.002

Udler, 2019, Type 2 diabetes: multiple genes, multiple diseases, Curr. Diab. Rep., 19, 55, 10.1007/s11892-019-1169-7

Wang, 2013, Spontaneous type 2 diabetic rodent models, J. Diabetes Res., 2013, 401723, 10.1155/2013/401723

Wang, 2019, Phenotypic characterization of a novel type 2 diabetes animal model in a SHANXI MU colony of Chinese hamsters, Endocrine., 65, 61, 10.1007/s12020-019-01940-x

Bauer, 2016, Targeting the gastrointestinal tract to treat type 2 diabetes, J. Endocrinol., 230, 95, 10.1530/JOE-16-0056

Duca, 2015, Glucoregulatory relevance of small intestinal nutrient sensing in physiology, bariatric surgery, and pharmacology, Cell Metab., 22, 367, 10.1016/j.cmet.2015.07.003

Wang, 2008, Upper intestinal lipids trigger a gut-brain-liver axis to regulate glucose production, Nature., 452, 1012, 10.1038/nature06852

Pedersen, 2016, Human gut microbes impact host serum metabolome and insulin sensitivity, Nature, 535, 376, 10.1038/nature18646

Jorsal, 2019, Investigating intestinal glucagon after roux-en-Y gastric bypass surgery, J. Clin. Endocrinol. Metab., 104, 6403, 10.1210/jc.2019-00062

Holst, 2016, Roles of the gut in glucose homeostasis, Diabetes Care, 39, 884, 10.2337/dc16-0351

Zhang, 2019, Comparative effects of proximal and distal small intestinal glucose exposure on glycemia, incretin hormone secretion, and the incretin effect in health and type 2 diabetes, Diabetes Care, 42, 520, 10.2337/dc18-2156

Chan, 2018, Na(+) /H(+) exchanger 3 blockade ameliorates type 2 diabetes mellitus via inhibition of sodium-glucose co-transporter 1-mediated glucose absorption in the small intestine, Diabetes Obes. Metab., 20, 709, 10.1111/dom.13151

Thongboonkerd, 2014, Recent advances of proteomics applied to human diseases, J. Proteome Res., 13, 4493, 10.1021/pr501038g

Edhager, 2018, Proteomics of the rat myocardium during development of type 2 diabetes mellitus reveals progressive alterations in major metabolic pathways, J. Proteome Res., 17, 2521, 10.1021/acs.jproteome.8b00276

James, 2015, Serum metabolomics in animal models and human disease, Curr. Opin. Clin. Nutr. Metab. Care, 18, 478, 10.1097/MCO.0000000000000200

Andrikopoulos, 2008, Evaluating the glucose tolerance test in mice, Am. J. Physiol. Endocrinol. Metab., 295, 1323, 10.1152/ajpendo.90617.2008

Wang, 2019, Plasma proteome profiling of high-altitude polycythemia using TMT-based quantitative proteomics approach, J. Proteome, 194, 60, 10.1016/j.jprot.2018.12.031

Qiu, 2009, Serum metabolite profiling of human colorectal cancer using GC-TOFMS and UPLC-QTOFMS, J. Proteome Res., 8, 4844, 10.1021/pr9004162

Xue, 2016, Comparative proteomic and metabolomic analysis reveal the antiosteoporotic molecular mechanism of icariin from Epimedium brevicornu maxim, J. Ethnopharmacol., 192, 370, 10.1016/j.jep.2016.07.037

Hoffman, 2020, Transcriptomic and metabolomic profiling of long-lived growth hormone releasing hormone knock-out mice: evidence for altered mitochondrial function and amino acid metabolism, Aging (Albany NY), 12, 3473, 10.18632/aging.102822

Dutta, 2012, Concordance of changes in metabolic pathways based on plasma metabolomics and skeletal muscle transcriptomics in type 1 diabetes, Diabetes., 61, 1004, 10.2337/db11-0874

Kim, 2017, Activation of intestinal olfactory receptor stimulates glucagon-like peptide-1 secretion in enteroendocrine cells and attenuates hyperglycemia in type 2 diabetic mice, Sci. Rep., 7, 13978, 10.1038/s41598-017-14086-5

Wang, 2018, Sirtuin 5 overexpression attenuates glucolipotoxicity-induced pancreatic beta cells apoptosis and dysfunction, Exp. Cell Res., 371, 205, 10.1016/j.yexcr.2018.08.011

Du, 2018, SIRT5 deacylates metabolism-related proteins and attenuates hepatic steatosis in Ob/Ob mice, EBioMedicine., 36, 347, 10.1016/j.ebiom.2018.09.037

Banerjee, 2014, Reactive metabolites and antioxidant gene polymorphisms in type 2 diabetes mellitus, Indian J. Hum. Genet., 20, 10, 10.4103/0971-6866.132747

Wurtz, 2012, Circulating metabolite predictors of glycemia in middle-aged men and women, Diabetes Care, 35, 1749, 10.2337/dc11-1838

Hart, 2013, The CTRB1/2 locus affects diabetes susceptibility and treatment via the incretin pathway, Diabetes, 62, 3275, 10.2337/db13-0227

Paul, 2019, Berberine mitigates high glucose-potentiated platelet aggregation and apoptosis by modulating aldose reductase and NADPH oxidase activity, Free Radic. Biol. Med., 130, 196, 10.1016/j.freeradbiomed.2018.10.453

Ponomarev, 2018, Fresh evidence for platelets as neuronal and innate immune cells: their role in the activation, differentiation, and deactivation of Th1, Th17, and tregs during tissue inflammation, Front. Immunol., 9, 406, 10.3389/fimmu.2018.00406

Natarajan, 2004, Lipid inflammatory mediators in diabetic vascular disease, Arterioscler. Thromb. Vasc. Biol., 24, 1542, 10.1161/01.ATV.0000133606.69732.4c

Dubois, 2017, Distinct but complementary contributions of PPAR isotypes to energy homeostasis, J. Clin. Invest., 127, 1202, 10.1172/JCI88894

Gar, 2018, Serum and plasma amino acids as markers of prediabetes, insulin resistance, and incident diabetes, Crit. Rev. Clin. Lab. Sci., 55, 21, 10.1080/10408363.2017.1414143

Sunny, 2015, Cross-talk between branched-chain amino acids and hepatic mitochondria is compromised in nonalcoholic fatty liver disease, Am. J. Physiol. Endocrinol. Metab., 309, 311, 10.1152/ajpendo.00161.2015

Jang, 2016, A branched-chain amino acid metabolite drives vascular fatty acid transport and causes insulin resistance, Nat. Med., 22, 421, 10.1038/nm.4057

Brosnan, 2006, Branched-chain amino acids: enzyme and substrate regulation, J. Nutr., 136, 207, 10.1093/jn/136.1.207S

Furst, 1998, Protein and amino acid metabolism and therapy: what is new and what has been left aside, Curr. Opin. Clin. Nutr. Metab. Care, 1, 59, 10.1097/00075197-199801000-00010

Owei, 2019, Amino acid signature predictive of incident prediabetes: a case-control study nested within the longitudinal pathobiology of prediabetes in a biracial cohort, Metabolism., 98, 76, 10.1016/j.metabol.2019.06.011

Adams, 2011, Emerging perspectives on essential amino acid metabolism in obesity and the insulin-resistant state, Adv. Nutr., 2, 445, 10.3945/an.111.000737

Chen, 2016, Tryptophan predicts the risk for future type 2 diabetes, PLoS One, 11

Wang, 2011, Metabolite profiles and the risk of developing diabetes, Nat. Med., 17, 448, 10.1038/nm.2307

Del Coco, 2019, NMR-based metabolomic approach tracks potential serum biomarkers of disease progression in patients with type 2 diabetes mellitus, J. Clin. Med., 8, 720, 10.3390/jcm8050720

Oste, 2020, High plasma branched-chain amino acids are associated with higher risk of post-transplant diabetes mellitus in renal transplant recipients, J. Clin. Med., 9, 511, 10.3390/jcm9020511

Jiang, 2014, The role of phosphoglycerate mutase 1 in tumor aerobic glycolysis and its potential therapeutic implications, Int. J. Cancer, 135, 1991, 10.1002/ijc.28637

Sharif, 2019, Phosphoglycerate mutase 1 in cancer: a promising target for diagnosis and therapy, IUBMB Life, 71, 1418, 10.1002/iub.2100

Okabe, 2018, Deletion of PHGDH in adipocytes improves glucose intolerance in diet-induced obese mice, Biochem. Biophys. Res. Commun., 504, 309, 10.1016/j.bbrc.2018.08.180

Ali, 2007, Hydrogen sulphide reduces insulin secretion from HIT-T15 cells by a KATP channel-dependent pathway, J. Endocrinol., 195, 105, 10.1677/JOE-07-0184

Tiffin, 2006, Computational disease gene identification: a concert of methods prioritizes type 2 diabetes and obesity candidate genes, Nucleic Acids Res., 34, 3067, 10.1093/nar/gkl381

Rochfort, 2005, Metabolomics reviewed: a new “omics” platform technology for systems biology and implications for natural products research, J. Nat. Prod., 68, 1813, 10.1021/np050255w