Small conductance calcium activated potassium (SK) channel dependent and independent effects of riluzole on neuropathic pain-related amygdala activity and behaviors in rats

Abarca, 2000, Neurochemical changes after morphine, dizocilpine or riluzole in the ventral posterolateral thalamic nuclei of rats with hyperalgesia, Eur. J. Pharmacol., 403, 67, 10.1016/S0014-2999(00)00502-1

Adelman, 2012, Small-conductance Ca2+-activated K+ channels: form and function, Annu. Rev. Physiol., 74, 245, 10.1146/annurev-physiol-020911-153336

Bahia, 2005, A functional role for small-conductance calcium-activated potassium channels in sensory pathways including nociceptive processes, J. Neurosci., 25, 3489, 10.1523/JNEUROSCI.0597-05.2005

Bellingham, 2011, A review of the neural mechanisms of action and clinical efficiency of riluzole in treating amyotrophic lateral sclerosis: what have we learned in the last decade?, CNS Neurosci. Ther., 17, 4, 10.1111/j.1755-5949.2009.00116.x

Bird, 2005, Protein kinase A-dependent enhanced NMDA receptor function in pain-related synaptic plasticity in rat amygdala neurones, J. Physiol., 564, 907, 10.1113/jphysiol.2005.084780

Blackburn-Munro, 2002, A comparison of the anti-nociceptive effects of voltage-activated Na+ channel blockers in the formalin test, Eur. J. Pharmacol., 445, 231, 10.1016/S0014-2999(02)01765-X

Bushnell, 2013, Cognitive and emotional control of pain and its disruption in chronic pain, Nat. Rev. Neurosci., 14, 502, 10.1038/nrn3516

Cao, 2002, Modulation of recombinant and native neuronal SK channels by the neuroprotective drug riluzole, Eur. J. Pharmacol., 449, 47, 10.1016/S0014-2999(02)01987-8

Carrasquillo, 2007, Activation of the extracellular signal-regulated kinase in the amygdala modulates pain perception, J. Neurosci., 27, 1543, 10.1523/JNEUROSCI.3536-06.2007

Carrasquillo, 2008, Hemispheric lateralization of a molecular signal for pain modulation in the amygdala, Mol. Pain, 4, 24, 10.1186/1744-8069-4-24

Chaplan, 1994, Quantitative assessment of tactile allodynia in the rat paw, J. Neurosci. Meth., 53, 55, 10.1016/0165-0270(94)90144-9

Chew, 2014, The effects of minocycline or riluzole treatment on spinal root avulsion-induced pain in adult rats, J. Pain, 15, 664

Coderre, 2007, A comparison of the glutamate release inhibition and anti-allodynic effects of gabapentin, lamotrigine, and riluzole in a model of neuropathic pain, J. Neurochem., 100, 1289, 10.1111/j.1471-4159.2006.04304.x

Cragg, 2016, Differential contributions of vasopressin V1A and oxytocin receptors in the amygdala to pain-related behaviors in rats, Mol. Pain, 12, 10.1177/1744806916676491

Curtis, 2015, Experimental design and analysis and their reporting: new guidance for publication in BJP, Br. J. Pharmacol., 172, 3461, 10.1111/bph.12856

Deflorio, 2014, Partial block by riluzole of muscle sodium channels in myotubes from amyotrophic lateral sclerosis patients, Neurol Res Int, 2014, 946073, 10.1155/2014/946073

Dixon, 1980, Efficient analysis of experimental observations, Annu. Rev. Pharmacol. Toxicol., 20, 441, 10.1146/annurev.pa.20.040180.002301

Faber, 2010, Functional interplay between NMDA receptors, SK channels and voltage-gated Ca2+ channels regulates synaptic excitability in the medial prefrontal cortex, J. Physiol., 588, 1281, 10.1113/jphysiol.2009.185645

Faber, 2005, SK channels regulate excitatory synaptic transmission and plasticity in the lateral amygdala, Nat. Neurosci., 8, 635, 10.1038/nn1450

Faber, 2007, Functions of SK channels in central neurons, Clin. Exp. Pharmacol. Physiol., 34, 1077, 10.1111/j.1440-1681.2007.04725.x

Finch, 1998, Local calcium signalling by inositol-1,4,5-trisphosphate in Purkinje cell dendrites, Nature, 396, 753, 10.1038/25541

Fiorillo, 1998, Glutamate mediates an inhibitory postsynaptic potential in dopamine neurons, Nature, 394, 78, 10.1038/27919

Fu, 2008, Differential mechanisms of CRF1 and CRF2 receptor functions in the amygdala in pain-related synaptic facilitation and behavior, J. Neurosci., 28, 3861, 10.1523/JNEUROSCI.0227-08.2008

Gaskin, 2012, The economic costs of pain in the United States, J. Pain, 13, 715

Goncalves, 2012, Asymmetric time-dependent activation of right central amygdala neurones in rats with peripheral neuropathy and pregabalin modulation, Eur. J. Neurosci., 36, 3204, 10.1111/j.1460-9568.2012.08235.x

Hama, 2011, Antinociceptive effect of riluzole in rats with neuropathic spinal cord injury pain, J. Neurotrauma, 28, 127, 10.1089/neu.2010.1539

Han, 2005, Computerized analysis of audible and ultrasonic vocalizations of rats as a standardized measure of pain-related behavior, J. Neurosci. Meth., 141, 261, 10.1016/j.jneumeth.2004.07.005

Hipolito, 2015, In vivo activation of the SK channel in the spinal cord reduces the NMDA receptor antagonist dose needed to produce antinociception in an inflammatory pain model, Pain, 156, 849, 10.1097/j.pain.0000000000000124

Ikeda, 2007, NMDA receptor-independent synaptic plasticity in the central amygdala in the rat model of neuropathic pain, Pain, 127, 161, 10.1016/j.pain.2006.09.003

Ji, 2013, Non-pain-related CRF1 activation in the amygdala facilitates synaptic transmission and pain responses, Mol. Pain, 9, 2, 10.1186/1744-8069-9-2

Ji, 2015, Reactive oxygen species mediate visceral pain-related amygdala plasticity and behaviors, Pain, 156, 825, 10.1097/j.pain.0000000000000120

Ji, 2009, Hemispheric lateralization of pain processing by amygdala neurons, J. Neurophysiol., 102, 2253, 10.1152/jn.00166.2009

Ji, 2010, Cognitive impairment in pain through amygdala-driven prefrontal cortical deactivation, J. Neurosci., 30, 5451, 10.1523/JNEUROSCI.0225-10.2010

Ji, 2017, 5-HT2C receptor knockdown in the amygdala inhibits neuropathic-pain-related plasticity and behaviors, J. Neurosci., 37, 1378, 10.1523/JNEUROSCI.2468-16.2016

Kasanetz, 2013, Prefrontal synaptic markers of cocaine addiction-like behavior in rats, Mol. Psychiatr., 18, 729, 10.1038/mp.2012.59

Kilkenny, 2010, Animal research: reporting in vivo experiments: the ARRIVE guidelines, Br. J. Pharmacol., 160, 1577, 10.1111/j.1476-5381.2010.00872.x

Kim, 2017, Monomethyl fumarate inhibits pain behaviors and amygdala activity in a rat arthritis model, Pain, 158, 2376, 10.1097/j.pain.0000000000001042

Kim, 1992, An experimental model for peripheral neuropathy produced by segmental spinal nerve ligation in the rat, Pain, 50, 355, 10.1016/0304-3959(92)90041-9

Kiritoshi, 2016, Rescue of impaired mGluR5-driven endocannabinoid signaling restores prefrontal cortical output to inhibit pain in arthritic rats, J. Neurosci., 36, 837, 10.1523/JNEUROSCI.4047-15.2016

Kiritoshi, 2015, Group II mGluRs modulate baseline and arthritis pain-related synaptic transmission in the rat medial prefrontal cortex, Neuropharmacology, 95, 388, 10.1016/j.neuropharm.2015.04.003

Li, 2011, Mitochondrial reactive oxygen species are activated by mGluR5 through IP3 and activate ERK and PKA to increase excitability of amygdala neurons and pain behavior, J. Neurosci., 31, 1114, 10.1523/JNEUROSCI.5387-10.2011

Lopez de Armentia, 2004, Firing properties and connectivity of neurons in the rat lateral central nucleus of the amygdala, J. Neurophysiol., 92, 1285, 10.1152/jn.00211.2004

McGrath, 2015, Implementing guidelines on reporting research using animals (ARRIVE etc.): new requirements for publication in BJP, Br. J. Pharmacol., 172, 3189, 10.1111/bph.12955

Medina, 2014, Nasal application of neuropeptide S inhibits arthritis pain-related behaviors through an action in the amygdala, Mol. Pain, 10, 32, 10.1186/1744-8069-10-32

Mezadri, 2011, Repeated rat-forced swim test: reducing the number of animals to evaluate gradual effects of antidepressants, J. Neurosci. Meth., 195, 200, 10.1016/j.jneumeth.2010.12.015

Monville, 2006, Comparison of incremental and accelerating protocols of the rotarod test for the assessment of motor deficits in the 6-OHDA model, J. Neurosci. Meth., 158, 219, 10.1016/j.jneumeth.2006.06.001

Moon, 2014, Riluzole attenuates neuropathic pain and enhances functional recovery in a rodent model of cervical spondylotic myelopathy, Neurobiol. Dis., 62, 394, 10.1016/j.nbd.2013.10.020

Morikawa, 2000, Inositol 1,4,5-triphosphate-evoked responses in midbrain dopamine neurons, J. Neurosci., 20, RC103, 10.1523/JNEUROSCI.20-20-j0003.2000

Morikawa, 2003, Two intracellular pathways mediate metabotropic glutamate receptor-induced Ca2+ mobilization in dopamine neurons, J. Neurosci., 23, 149, 10.1523/JNEUROSCI.23-01-00149.2003

Munro, 2007, Pharmacological comparison of anticonvulsant drugs in animal models of persistent pain and anxiety, Neuropharmacology, 53, 609, 10.1016/j.neuropharm.2007.07.002

Nakamura, 1999, Synergistic release of Ca2+ from IP3-sensitive stores evoked by synaptic activation of mGluRs paired with backpropagating action potentials, Neuron, 24, 727, 10.1016/S0896-6273(00)81125-3

Neugebauer, 2015, Amygdala pain mechanisms, Handb. Exp. Pharmacol., 227, 261, 10.1007/978-3-662-46450-2_13

Neugebauer, 2007, Techniques for assessing knee joint pain in arthritis, Mol. Pain, 3, 8, 10.1186/1744-8069-3-8

Neugebauer, 2003, Synaptic plasticity in the amygdala in a model of arthritic pain: differential roles of metabotropic glutamate receptors 1 and 5, J. Neurosci., 23, 52, 10.1523/JNEUROSCI.23-01-00052.2003

Pagadala, 2013, Loss of NR1 subunit of NMDARs in primary sensory neurons leads to hyperexcitability and pain hypersensitivity: involvement of Ca(2+)-activated small conductance potassium channels, J. Neurosci., 33, 13425, 10.1523/JNEUROSCI.0454-13.2013

Palazzo, 2002, Interaction between vanilloid and glutamate receptors in the central modulation of nociception, Eur. J. Pharmacol., 439, 69, 10.1016/S0014-2999(02)01367-5

Paxinos, 1998

Phelps, 2005, Contributions of the amygdala to emotion processing: from animal models to human behavior, Neuron, 48, 175, 10.1016/j.neuron.2005.09.025

Ren, 2013, Neuropeptide S: a novel regulator of pain-related amygdala plasticity and behaviors, J. Neurophysiol., 110, 1765, 10.1152/jn.00874.2012

Ren, 2010, Pain-related increase of excitatory transmission and decrease of inhibitory transmission in the central nucleus of the amygdala are mediated by mGluR1, Mol. Pain, 6, 93, 10.1186/1744-8069-6-93

Slattery, 2012, Using the rat forced swim test to assess antidepressant-like activity in rodents, Nat. Protoc., 7, 1009, 10.1038/nprot.2012.044

Stiller, 2003, Microdialysis in pain research, Adv. Drug Deliv. Rev., 55, 1065, 10.1016/S0169-409X(03)00104-2

Sun, 2015, Fear conditioning suppresses large-conductance calcium-activated potassium channels in lateral amygdala neurons, Physiol. Behav., 138, 279, 10.1016/j.physbeh.2014.10.005

Sung, 2003, Altered expression and uptake activity of spinal glutamate transporters after nerve injury contribute to the pathogenesis of neuropathic pain in rats, J. Neurosci., 23, 2899, 10.1523/JNEUROSCI.23-07-02899.2003

Takechi, 1998, A new class of synaptic response involving calcium release in dendritic spines, Nature, 396, 757, 10.1038/25547

Thompson, 2015, Small-conductance calcium-activated potassium (SK) channels in the amygdala mediate pain-inhibiting effects of clinically available riluzole in a rat model of arthritis pain, Mol. Pain, 11, 51, 10.1186/s12990-015-0055-9

Thompson, 2017, Amygdala plasticity and pain, Pain Res. Manag., 2017, 8296501, 10.1155/2017/8296501

Urbach, 2014, Automated phenotyping and advanced data mining exemplified in rats transgenic for Huntington's disease, J. Neurosci. Meth., 234, 38, 10.1016/j.jneumeth.2014.06.017