Small-Dose S(+)-Ketamine Reduces Postoperative Pain When Applied with Ropivacaine in Epidural Anesthesia for Total Knee Arthroplasty

Capdevila, 1999, Effects of perioperative analgesic technique on the surgical outcome and duration of rehabilitation after major knee surgery., Anesthesiology, 91, 8, 10.1097/00000542-199907000-00006

Woolf, 1993, Preemptive analgesia: treating postoperative pain by preventing the establishment of central sensitization., Anesth Analg, 77, 362, 10.1213/00000539-199377020-00026

Yaksh, 1999, The spinal biology in humans and animals of pain states generated by persistent afferent input., Proc Natl Acad Sci U S A, 96, 7680, 10.1073/pnas.96.14.7680

Orser, 1997, Multiple mechanisms of ketamine blockade of N-methyl-d-aspartate receptors., Anesthesiology, 86, 903, 10.1097/00000542-199704000-00021

Øye, 1992, Effects of ketamine on sensory perception: evidence for a role of N-methyl-d-aspartate receptors., J Pharmacol Exp Ther, 260, 1209

Aida, 2000, Preemptive analgesia by intravenous low-dose ketamine and epidural morphine in gastrectomy: a randomized double-blind study., Anesthesiology, 92, 1624, 10.1097/00000542-200006000-00020

Suzuki, 1999, Small-dose ketamine enhances morphine-induced analgesia after outpatient surgery., Anesth Analg, 89, 98, 10.1213/00000539-199907000-00017

Choe, 1997, Epidural morphine plus ketamine for upper abdominal surgery: improved analgesia from preincisional versus postincisional administration., Anesth Analg, 84, 560

Wong, 1997, Pre-emptive analgesia with ketamine, morphine and epidural lidocaine prior to total knee replacement., Can J Anaesth, 44, 31, 10.1007/BF03014321

Abdel-Ghaffar, 1998, Epidural ketamine reduces postoperative epidural PCA consumption of fentanyl/bupivacaine., Can J Anaesth, 45, 103, 10.1007/BF03013246

Zeilhofer, 1992, Differential effects of ketamine enantiomers on NMDA receptor currents in cultured neurons., Eur J Pharmacol, 213, 155, 10.1016/0014-2999(92)90248-3

Mathisen, 1995, Effect of ketamine, an NMDA receptor inhibitor, in acute and chronic orofacial pain., Pain, 61, 215, 10.1016/0304-3959(94)00170-J

Arendt-Nielsen, 1996, Effect of racemic mixture and the (S+)-isomer of ketamine on temporal and spatial summation of pain., Br J Anaesth, 77, 625, 10.1093/bja/77.5.625

Muldoon, 1998, Comparison between extradural infusion of ropivacaine or bupivacaine for the prevention of postoperative pain after total knee arthroplasty., Br J Anaesth, 80, 680, 10.1093/bja/80.5.680

Karpinsky, 1997, Subpial vacuolar myelopathy after intrathecal ketamine: report of a case., Pain, 73, 103, 10.1016/S0304-3959(97)00068-7

Errando, 1999, Subarachnoid ketamine in swine: pathological findings after repeated doses—acute toxicity study., Reg Anesth Pain Med, 24, 146

Yang, 1996, Intrathecal ketamine reduces morphine requirements in patients with terminal cancer pain., Can J Anaesth, 43, 379, 10.1007/BF03011718

Pedraz, 1991, Pharmacokinetics and distribution of ketamine after extradural administration in dogs., Br J Anaesth, 67, 310, 10.1093/bja/67.3.310

Pedraz, 1987, Pharmacokinetic and clinical evaluation of ketamine administered by IV and epidural routes., Int J Clin Pharmacol Ther Toxicol, 25, 77

Weir, 1998, Double-blind comparison of extradural block with three bupivacaine-ketamine mixtures in knee arthroplasty., Br J Anaesth, 80, 299, 10.1093/bja/80.3.299

Hatrick, 1997, Preemptive intrathecal ketamine delays mechanical hyperalgesia in the neuropathic rat., Anesth Analg, 86, 557

Kucuk, 1998, Preoperative epidural ketamine does not have a postoperative opioid sparing effect., Anesth Analg, 87, 103, 10.1213/00000539-199807000-00022

Gottrup, 2000, Differential effects of systemically administered ketamine and lidocaine on dynamic and static hyperalgesia induced by intradermal capsaicin in humans., Br J Anaesth, 84, 155, 10.1093/oxfordjournals.bja.a013396

Brennum, 1994, Quantitative sensory examination in human epidural anaesthesia and analgesia in man: dose-response effect of bupivacaine., Pain, 56, 315, 10.1016/0304-3959(94)90170-8

Bonhaus, 1988, N-methyl-d-aspartate receptor regulation of uncompetitive antagonist binding in rat membranes: kinetic analysis., Mol Pharmacol, 34, 250