Sleep and Cancer: Clinical Studies and Opportunities for Personalized Medicine
Tóm tắt
Both cancer and sleep disorders are two of the main problems of modern society with a high impact on public health. The present review analyzes the most recent and relevant clinical and epidemiological studies that explore the relationship between cancer and shift work, cancer and sleep duration, and cancer and sleep apnea. It also reviews the limitations of the present studies and explores the future challenges in personalized medicine in this field. The latest research in sleep and cancer is contradictory due to key limitations such as study design and lack of consideration of other sleep problems apart from the specific one being analyzed. Different studies have reached opposite conclusions in regards to the association of cancer with sleep duration and sleep quality; only the association between sleep timing and cancer seems to be well established. Recent studies have identified a possible association between sleep apnea and cancer, but further studies should be performed to clearly demonstrate the putative causality of this association. There is not a clear association between specific sleep characteristics and cancer. New studies should be performed to evaluate the impact of sleep quality and sleep-related diseases, such as sleep apnea, with cancer.
Tài liệu tham khảo
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