Skin flora: Differences between people affected by Albinism and those with normally pigmented skin in Northern Tanzania – cross sectional study

Springer Science and Business Media LLC - Tập 12 - Trang 1-4 - 2012
Samson K Kiprono1, John E Masenga1, Baraka M Chaula1, Bernard Naafs1,2
1Department of Dermatology, Regional Dermatology Training Center, Moshi, Tanzania
2Stichting Tropendermatologie, Munnekeburen, The Netherlands

Tóm tắt

Skin flora varies from one site of the body to another. Individual’s health, age and gender determine the type and the density of skin flora. A 1 cm2 of the skin on the sternum was rubbed with sterile cotton swab socked in 0.9% normal saline and plated on blood agar. This was cultured at 35°C. The bacteria were identified by culturing on MacConkey agar, coagulase test, catalase test and gram staining. Swabs were obtained from 66 individuals affected by albinism and 31 individuals with normal skin pigmentation. Those with normal skin were either relatives or staying with the individuals affected by albinism who were recruited for the study. The mean age of the 97 recruited individuals was 30.6 (SD ± 14.9) years. The mean of the colony forming units was 1580.5 per cm2. Those affected by albinism had a significantly higher mean colony forming units (1680 CFU per cm2) as compared with 453.5 CFU per cm2 in those with normally pigmented skin (p = 0.023). The skin type and the severity of sun- damaged skin was significantly associated with a higher number of colony forming units (p = 0.038). Individuals affected by albinism have a higher number of colony forming units which is associated with sun- damaged skin.

Tài liệu tham khảo

Kong HH: Skin microbiome: genomics-based insights into the diversity and role of skin microbes. Trends Mol Med 2011,17(6):320–328. 10.1016/j.molmed.2011.01.013 Grice EA, Segre JA: The skin microbiome. Nature Rev Microbiol 2011, 9: 244–253. 10.1038/nrmicro2537 Noble WC: The skin microflora and microbial diseases. Philadelphia PA, Cambridge University Press; 2004. Thamlikitkul V, Santiprasitkul S, Suntanondra L, et al.: Skin flora of patients in Thailand. Am J Infect Control 2003, 31: 80–84. 10.1067/mic.2003.64 Larson EL, Cronquist BA, Whittier S, Lai L, Lyle CT, Latta PD: Differences in skin flora between inpatients and chronically ill outpatients. Heart Lung 2000, 29: 298–305. 10.1067/mhl.2000.108324 Marples RR: Sex, constancy, and skin bacteria. Arch Dermatol Res 1982, 272: 317–320. 10.1007/BF00509062 Larson EL, Hughes CAN, Pyrek JD, Sparks SM, Cagatay EU, Bartkus JM: Changes in bacterial flora associated with skin damage on hands of health care personnel. Am J Infect Control 1998, 26: 513–521. 10.1016/S0196-6553(98)70025-2 Leyden JJ, McGinley KJ, Nordstrom KM, Webster GF: Skin microflora. J Invest Dermatol 1987, 88: 65s-72s. 10.1111/1523-1747.ep12468965 Fierer N, Lauber CL, Zhou N, McDonald D, Costello EK, Knight R: Forensic identification using skin bacterial communities. Proc Natl Acad Sci USA 2010, 107: 6477–6481. 10.1073/pnas.1000162107 Faergemann J, Larko O: The effect of UV-light on human skin microorganisms. Acta Derm Venereol 1987, 67: 69–72. Hanneman KK, Cooper KD, Baron ED: Ultraviolet immunosuppression: mechanisms and consequences. Dermatol Clin 2006,24(1):19–25. 10.1016/j.det.2005.08.003 Larson EL, Gomes-Duarte C, Lee LV, Della-Latta P, Kain DJ, Keswick BH: Microflora of hands of homemakers. Am J Infect Control 2003, 31: 72–9. 10.1067/mic.2003.33 Borges LF, Silva BL, Filho PP, Gerais M: Hand washing: Changes in the skin flora. Am J Infect Control 2007, 35: 417–20. 10.1016/j.ajic.2006.07.012 The pre-publication history for this paper can be accessed here:http://www.biomedcentral.com/1471-5945/12/12/prepub