Size, shape, charge and “stealthy” surface: Carrier properties affect the drug circulation time in vivo

Asian Journal of Pharmaceutical Sciences - Tập 16 - Trang 444-458 - 2021
Jinwei Di1, Xiang Gao1, Yimeng Du1, Hui Zhang1, Jing Gao1, Aiping Zheng1
1State Key Laboratory of Toxicology and Medical Countermeasures, Beijing Institute of Pharmacology and Toxicology, Beijing, 100850, China

Tài liệu tham khảo

Merisko-Liversidge, 2003, Nanosizing: a formulation approach for poorly-water-soluble compounds, Eur J Pharm Sci, 18, 113, 10.1016/S0928-0987(02)00251-8 Loftsson, 2010, Pharmaceutical applications of cyclodextrins: basic science and product development, J Pharm Pharmacol, 62, 1607, 10.1111/j.2042-7158.2010.01030.x Kalepu, 2015, Insoluble drug delivery strategies: review of recent advances and business prospects, Acta Pharm Sin B, 5, 442, 10.1016/j.apsb.2015.07.003 He, 2019, Adapting liposomes for oral drug delivery, Acta Pharm Sin B, 9, 36, 10.1016/j.apsb.2018.06.005 Danhier, 2012, PLGA-based nanoparticles: an overview of biomedical applications, J Controlled Release, 161, 505, 10.1016/j.jconrel.2012.01.043 Strebhardt, 2008, Paul Ehrlich's magic bullet concept: 100 years of progress, Nat Rev Cancer, 8, 473, 10.1038/nrc2394 da Silva, 2019, Recent advances in the use of metallic nanoparticles with antitumoral action - review, Curr Med Chem, 26, 2108, 10.2174/0929867325666180214102918 Baeza, 2016, Recent advances in porous nanoparticles for drug delivery in antitumoral applications: inorganic nanoparticles and nanoscale metal-organic frameworks, Expert Opin Drug Delivery, 14, 783, 10.1080/17425247.2016.1229298 Masse, 2019, Gold nanoparticles in ophthalmology, Med Res Rev, 39, 302, 10.1002/med.21509 Zhang, 2019, Advance and application of DNA-functionalized nanoparticles, Curr Med Chem, 26, 7147, 10.2174/0929867325666180501103620 Pugazhendhi, 2018, Inorganic nanoparticles: a potential cancer therapy for human welfare, Int J Pharm, 539, 104, 10.1016/j.ijpharm.2018.01.034 Kumar, 2011, Gold nanoparticles: promising nanomaterials for the diagnosis of cancer and HIV/AIDS, J Nanomater, 17, 1687 Ramalho, 2018, Receptor-mediated PLGA nanoparticles for glioblastoma multiforme treatment, Int J Pharm, 545, 84, 10.1016/j.ijpharm.2018.04.062 Yang, 2017, Nanoparticles for modulating tumor microenvironment to improve drug delivery and tumor therapy, Pharmacol Res, 126, 97, 10.1016/j.phrs.2017.05.004 Xing, 2017, Lipid nanoparticles for the delivery of active natural medicines, Curr Pharm Des, 23, 6705, 10.2174/1381612824666171128105853 Muller, 2004, Challenges and solutions for the delivery of biotech drugs – a review of drug nanocrystal technology and lipid nanoparticles, J Biotechnol, 113, 151, 10.1016/j.jbiotec.2004.06.007 Haruma, 2000, Functional polymer microspheres, Prog Polym Sci, 25, 1171, 10.1016/S0079-6700(00)00024-1 Uyen, 2020, Fabrication of alginate microspheres for drug delivery: a review, Int J Biol Macromol, 153, 1035, 10.1016/j.ijbiomac.2019.10.233 Dhamecha, 2019, Applications of alginate microspheres in therapeutics delivery and cell culture: past, present and future, Int J Pharm, 569, 10.1016/j.ijpharm.2019.118627 Ghosh Dastidar, 2018, Porous microspheres: synthesis, characterisation and applications in pharmaceutical & medical fields, Int J Pharm, 548, 34, 10.1016/j.ijpharm.2018.06.015 Koerner, 2019, Harnessing dendritic cells for poly (D,L-lactide-co-glycolide) microspheres (PLGA MS)-mediated anti-tumor therapy, Front Immunol, 10, 1, 10.3389/fimmu.2019.00707 Yang, 2019, Recent advance in polymer based microspheric systems for controlled protein and peptide delivery, Curr Med Chem, 26, 2285, 10.2174/0929867326666190409130207 Xia, 2019, Red blood cell membrane-camouflaged nanoparticles: a novel drug delivery system for antitumor application, Acta Pharm Sin B, 9, 675, 10.1016/j.apsb.2019.01.011 Jiang, 2017, Red blood cell membrane-camouflaged melanin nanoparticles for enhanced photothermal therapy, Biomaterials, 143, 29, 10.1016/j.biomaterials.2017.07.027 Chen, 2017, Cell membrane camouflaged hollow prussian blue nanoparticles for synergistic photothermal-/chemotherapy of cancer, Adv Funct Mater, 27, 1605795, 10.1002/adfm.201605795 Pei, 2018, Light-activatable red blood cell membrane-camouflaged dimeric prodrug nanoparticles for synergistic photodynamic/chemotherapy, ACS Nano, 12, 1630, 10.1021/acsnano.7b08219 Rao, 2017, Antitumor platelet-mimicking magnetic nanoparticles, Adv Funct Mater, 27, 10.1002/adfm.201604774 Rao, 2016, Cancer cell membrane-coated upconversion nanoprobes for highly specific tumor imaging, Adv Materials, 28, 3460, 10.1002/adma.201506086 Gao, 2015, Modulating antibacterial immunity via bacterial membrane-coated nanoparticles, Nano lett, 15, 1403, 10.1021/nl504798g Gao, 2016, Stem cell membrane-coated nanogels for highly efficient in vivo tumor targeted drug delivery, Small, 12, 4056, 10.1002/smll.201600624 Li, 2018, Cell membrane-based nanoparticles: a new biomimetic platform for tumor diagnosis and treatment, Acta Pharm Sin B, 8, 14, 10.1016/j.apsb.2017.11.009 Zhao, 2019, Effect of physicochemical and surface properties on in vivo fate of drug nanocarriers, Adv Drug Delivery Rev, 143, 3, 10.1016/j.addr.2019.01.002 Wilhelm, 2016, Analysis of nanoparticle delivery to tumours, Nat Rev Mater, 1, 16014, 10.1038/natrevmats.2016.14 Tsoi, 2016, Mechanism of hard-nanomaterial clearance by the liver, Nat Mater, 15, 1212, 10.1038/nmat4718 MacParland, 2017, Phenotype determines nanoparticle uptake by human macrophages from liver and blood, ACS Nano, 11, 2428, 10.1021/acsnano.6b06245 Zhang, 2016, Nanoparticle-liver interactions: cellular uptake and hepatobiliary elimination, J Controlled Release, 240, 332, 10.1016/j.jconrel.2016.01.020 Gordon, 2014, Macrophage heterogeneity in tissues: phenotypic diversity and functions, Immunol Rev, 262, 36, 10.1111/imr.12223 Canton, 2013, Scavenger receptors in homeostasis and immunity, Nat Rev Immunol, 13, 621, 10.1038/nri3515 Phagocytosis, 2020, phenotypically simple yet a mechanistically complex process, Int Rev Immunol, 29, 118 Wu, 2009, Galactosylated LDL nanoparticles: a novel targeting delivery system to deliver antigen to macrophages and enhance antigen specific T cell responses, Mol Pharmaceutics, 6, 1506, 10.1021/mp900081y Rahabi, 2020, Divergent roles for macrophage c-type lectin receptors, dectin-1 and mannose receptors, in the intestinal inflammatory response, Cell Rep, 30, 4386, 10.1016/j.celrep.2020.03.018 Lubow J., Virgilio M.C., Merlino M., Collins D.R., Mashiba M., Peterson B.G., et al. Mannose receptor is an HIV restriction factor counteracted by VPR in macrophages. eLife2020;9:51035. Lubbers, 2017, Production of complement components by cells of the immune system, Clin Exp Immunol, 188, 183, 10.1111/cei.12952 Moghimi, 2019, The interplay between blood proteins, complement, and macrophages on nanomedicine performance and responses, J Pharmacol Exp Ther, 370, 581, 10.1124/jpet.119.258012 Kang, 2009, Target pattern recognition by complement proteins of the classical and alternative pathways, Adv Exp Med Biol, 653, 117, 10.1007/978-1-4419-0901-5_8 Hamad, 2010, Distinct polymer architecture mediates switching of complement activation pathways at the nanosphere-serum interface: implications for stealth nanoparticle engineering, ACS Nano, 4, 6629, 10.1021/nn101990a Liu, 2018, Complement c3 produced by macrophages promotes renal fibrosis via il-17a secretion, Front Immunol, 9, 2385, 10.3389/fimmu.2018.02385 Wang, 2011, MR Imaging of activated hepatic stellate cells in liver injured by CCl4 of rats with integrin-targeted ultrasmall superparamagnetic iron oxide, Eur Radiol, 21, 1016, 10.1007/s00330-010-1988-z Higashi, 2017, Hepatic stellate cells as key target in liver fibrosis, Adv Drug Delivery Rev, 121, 27, 10.1016/j.addr.2017.05.007 DeLeve, 2015, Liver sinusoidal endothelial cells in hepatic fibrosis, Hepatology, 61, 1740, 10.1002/hep.27376 Chithrani, 2006, Determining the size and shape dependence of gold nanoparticle uptake into mammalian cells, Nano lett, 6, 662, 10.1021/nl052396o Gratton, 2008, The effect of particle design on cellular internalization pathways, Proc Natl Acad Sci USA, 105, 11613, 10.1073/pnas.0801763105 Arnida, 2011, Geometry and surface characteristics of gold nanoparticles influence their biodistribution and uptake by macrophages, Eur J Pharm Biopharm, 77, 417, 10.1016/j.ejpb.2010.11.010 Jo, 2015, Size, surface charge, and shape determine therapeutic effects of nanoparticles on brain and retinal diseases, Nanomedicine, 11, 1603, 10.1016/j.nano.2015.04.015 Zhang, 2018, Advances in long-circulating drug delivery strategy, Curr Drug Metab, 19, 750, 10.2174/1389200219666180511152350 Sanejaa, 2017, Development and evaluation of long-circulating nanoparticles loaded with betulinic acid for improved anti-tumor efficacy, Int J Pharm, 531, 153, 10.1016/j.ijpharm.2017.08.076 Wang, 2013, The research of anti-tumor drugs long circulating polymeric liposomes, Prog Biochem Biophys, 40, 1063 Kim, 2011, Cytotoxicity of, and innate immune response to, size-controlled polypyrrole nanoparticles in mammalian cells, Biomaterials, 32, 2342, 10.1016/j.biomaterials.2010.11.080 Yue, 2010, Particle size affects the cellular response in macrophages, Eur J Pharm Sci, 41, 650, 10.1016/j.ejps.2010.09.006 Jasinski, 2018, The effect of size and shape of RNA nanoparticles on biodistribution, Mol Ther, 26, 784, 10.1016/j.ymthe.2017.12.018 Fang, 2006, In vivo tumor targeting of tumor necrosis factor-alpha-loaded stealth nanoparticles: effect of MePEG molecular weight and particle size, Eur J Pharm Sci, 27, 27, 10.1016/j.ejps.2005.08.002 Doshi, 2010, Macrophages recognize size and shape of their targets, PLoS ONE, 5, e10051, 10.1371/journal.pone.0010051 Champion, 2008, Role of particle size in phagocytosis of polymeric microspheres, Pharm Res, 25, 1815, 10.1007/s11095-008-9562-y Kawaguchi, 1986, Phagocytosis of latex particles by leucocytes. I. Dependence of phagocytosis on the size and surface potential of particles, Biomaterials, 7, 61, 10.1016/0142-9612(86)90091-8 Longmire, 2008, Clearance properties of nano-sized particles and molecules as imaging agents: considerations and caveats, Nanomedicine, 3, 703, 10.2217/17435889.3.5.703 Hardonk, 1985, Zonal heterogeneity of rat hepatocytes in the in vivo uptake of 17nm colloidal gold granules, Histochemistry, 83, 473, 10.1007/BF00509211 Gunawan, 2014, Nanoparticle–protein corona complexes govern the biological fates and functions of nanoparticles, J Mater Chem B, 2, 2060, 10.1039/c3tb21526a You, 2011, Targeted drug delivery to tumors: myths, reality and possibility, J Controlled Release, 153, 198, 10.1016/j.jconrel.2011.06.001 Rijcken, 2007, Hydrolysable core-crosslinked thermosensitive polymeric micelles: synthesis, characterisation and in vivo studies, Biomaterials, 28, 5581, 10.1016/j.biomaterials.2007.08.047 Rejman, 2004, Size-dependent internalization of particles via the pathways of clathrin-and caveolae-mediated endocytosis, Biochem J, 377, 159, 10.1042/bj20031253 Fretz, 2006, Effects of Na+/H+ exchanger inhibitors on subcellular localisation of endocytic organelles and intracellular dynamics of protein transduction domains HIV-TAT peptide and octaarginine, J Controlled Release, 116, 247, 10.1016/j.jconrel.2006.07.009 Hansen, 2009, Molecular mechanisms of clathrin-independent endocytosis, J Cell Sci, 122, 1713, 10.1242/jcs.033951 Moore, 2006, Do nanoparticles present ecotoxicological risks for the health of the aquatic environment?, Environ Int, 32, 967, 10.1016/j.envint.2006.06.014 Champion, 2006, From the cover: role of target geometry in phagocytosis, Proc Natl Acad Sci, 103, 4930, 10.1073/pnas.0600997103 Luo, 2020, Dual and multi-targeted nanoparticles for site-specific brain drug delivery, J Controlled Release, 317, 195, 10.1016/j.jconrel.2019.11.037 Saidijam, 2018, Efflux proteins at the blood-brain barrier: review and bioinformatics analysis, Xenobiotica, 48, 506, 10.1080/00498254.2017.1328148 Ferreira, 2019, What human blood-brain barrier models can tell us about BBB function and drug discovery?, Expert Opin Drug Discovery, 14, 1113, 10.1080/17460441.2019.1646722 Tosi, 2020, Nanoparticles as carriers for drug delivery of macromolecules across the blood-brain barrier, Expert Opin Drug Discovery, 17, 23, 10.1080/17425247.2020.1698544 Diaz-Coranguez, 2017, The inner blood-retinal barrier: cellular basis and development, Vision Res, 139, 123, 10.1016/j.visres.2017.05.009 Li, 2004, Transference of tinidazole across the blood-pancreas barrier in rats, Her Med, 23, 525 West, 2003, Thoughts on the pulmonary blood-gas barrier, Am J Physiol: Lung Cell Mol Physiol, 285, L501 Tetro, 2018, The placental barrier: the gate and the fate in drug distribution, Pharm Res, 35, 71, 10.1007/s11095-017-2286-0 Ensign, 2011, Oral drug delivery with polymeric nanoparticles: the gastrointestinal mucus barriers, Adv Drug Delivery Rev, 64, 557, 10.1016/j.addr.2011.12.009 Lichtenberger, 1995, The hydrophobic barrier properties of gastrointestinal mucus, Annu Rev Physiol, 57, 565, 10.1146/annurev.ph.57.030195.003025 Nowak, 2020, Delivery of nanoparticles and macromolecules across the blood-brain barrier, Adv Ther, 3 Nowak, 2020, Size, shape, and flexibility influence nanoparticle transport across brain endothelium under flow, Bioeng Transl Med, 5, e10153, 10.1002/btm2.10153 Murgia, 2017, The role of mucus on drug transport and its potential to affect therapeutic outcomes, Adv Drug Delivery Rev, 124, 82, 10.1016/j.addr.2017.10.009 Choi, 2007, Renal clearance of quantum dots, Nat Biotechnol, 25, 1165, 10.1038/nbt1340 Kulkarni, 2013, Effects of particle size and surface modification on cellular uptake and biodistribution of polymeric nanoparticles for drug delivery, Pharm Res, 30, 2512, 10.1007/s11095-012-0958-3 de Barros, 2012, Emerging role of radiolabeled nanoparticles as an effective diagnostic technique, EJNMMI Res, 2, 39, 10.1186/2191-219X-2-39 Faraji, 2009, Nanoparticles in cellular drug delivery, Bioorg Med Chem, 17, 2950, 10.1016/j.bmc.2009.02.043 Vonarbourg, 2006, Parameters influencing the stealthiness of colloidal drug delivery systems, Biomaterials, 27, 4356, 10.1016/j.biomaterials.2006.03.039 Caster, 2017, Effect of particle size on the biodistribution, toxicity, and efficacy of drug-loaded polymeric nanoparticles in chemoradiotherapy, Nanomedicine, 13, 1673, 10.1016/j.nano.2017.03.002 Hoshyar, 2016, The effect of nanoparticle size on in vivo pharmacokinetics and cellular interaction, Nanomedicine, 11, 673, 10.2217/nnm.16.5 Champion, 2009, Shape induced inhibition of phagocytosis of polymer particles, Pharm Res, 26, 244, 10.1007/s11095-008-9626-z Favi, 2015, Shape and surface chemistry effects on the cytotoxicity and cellular uptake of metallic nanorods and nanospheres, J Biomed Mater Res Part A, 103, 3940, 10.1002/jbm.a.35518 Favi, 2015, Shape and surface effects on the cytotoxicity of nanoparticles: gold nanospheres versus gold nanostars, J Biomed Mater Res Part A, 103, 3449, 10.1002/jbm.a.35491 Li, 2016, Gold nanoparticle size and shape influence on osteogenesis of mesenchymal stem cells, Nanoscale, 21, 7992, 10.1039/C5NR08808A Doshi, 2010, Flow and adhesion of drug carriers in blood vessels depend on their shape: a study using model synthetic microvascular networks, J Controlled Release, 146, 196, 10.1016/j.jconrel.2010.04.007 Velev, 2000, A class of microstructured particles through colloidal crystallization, Science, 287, 2240, 10.1126/science.287.5461.2240 Xu, 2005, Generation of monodisperse particles by using microfluidics: control over size, shape, and composition, Angew Chem Int Ed, 117, 734, 10.1002/ange.200462226 Huang, 2010, The effect of the shape of mesoporous silica nanoparticles on cellular uptake and cell function, Biomaterials, 31, 438, 10.1016/j.biomaterials.2009.09.060 Geng, 2007, Shape effects of filaments versus spherical particles in flow and drug delivery, Nat Nanotechnol, 2, 249, 10.1038/nnano.2007.70 Han, 2015, Dual-pH sensitive charge-reversal polypeptide micelles for tumor-triggered targeting uptake and nuclear drug delivery, Small, 11, 2543, 10.1002/smll.201402865 Kenzaoui, 2012, Evaluation of uptake and transport of cationic and anionic ultrasmall iron oxide nanoparticles by human colon cells, Int J Nanomed, 7, 1275 Petri-Fink, 2005, Development of functionalized superparamagnetic iron oxide nanoparticles for interaction with human cancer cells, Biomaterials, 26, 2685, 10.1016/j.biomaterials.2004.07.023 Merhi, 2012, Study of serum interaction with a cationic nanoparticle: implications for in vitro endocytosis, cytotoxicity and genotoxicity, Int J Pharm, 423, 37, 10.1016/j.ijpharm.2011.07.014 Du, 2011, Tailor-made dual pH-sensitive polymer-doxorubicin nanoparticles for efficient anticancer drug delivery, J Am Chem Soc, 133, 17560, 10.1021/ja207150n Yue, 2011, Surface charge affects cellular uptake and intracellular trafficking of chitosan-based nanoparticles, Biomacromolecules, 12, 2440, 10.1021/bm101482r Xie, 2020, pH-responsive surface charge reversal carboxymethyl chitosan-based drug delivery system for pH and reduction dual-responsive triggered DOX release, Carbohydr Polym, 236, 10.1016/j.carbpol.2020.116093 Ahmed, 2014, Multicomponent polymeric nanoparticles enhancing intracellular drug release in cancer cells, ACS Appl Mater Interfaces, 6, 21316, 10.1021/am5061933 Xu, 2020, A pH-responsive charge-reversal drug delivery system with tumor-specific drug release and ROS generation for cancer therapy, Int J Nanomed, 15, 65, 10.2147/IJN.S230237 Xu, 2018, pH-triggered charge-reversal and redox-sensitive drug-release polymer micelles codeliver doxorubicin and triptolide for prostate tumor therapy, Int J Nanomed, 13, 7229, 10.2147/IJN.S182197 Xu, 2009, Long-circulation of hemoglobin-loaded polymeric nanoparticles as oxygen carriers with modulated surface charges, Int J Pharm, 377, 199, 10.1016/j.ijpharm.2009.05.015 Roser, 1998, Surface-modified biodegradable albumin nano- and microspheres II: effect of surface charges on in vitro phagocytosis and biodistribution in rats, Eur J Pharm Biopharm, 46, 255, 10.1016/S0939-6411(98)00038-1 Hu, 2016, Activated charge-reversal polymeric nano-system: the promising strategy in drug delivery for cancer therapy, Polymers (Basel), 8, 1 Zhao, 2019, Polyelectrolyte-based platforms for the delivery of peptides and proteins, ACS Biomater Sci Eng, 5, 4937, 10.1021/acsbiomaterials.9b01135 Mummert, 2005, Immunologic roles of hyaluronan, Immunol Res, 31, 189, 10.1385/IR:31:3:189 Suzuki, 2000, Influence of physico-chemical properties of chitin and chitosan on complement activation, Carbohydr Polym, 42, 307, 10.1016/S0144-8617(99)00161-7 Suzuki, 2003, Influence of the chain length of chitosan on complement activation, Carbohydr Polym, 54, 465, 10.1016/j.carbpol.2003.07.002 Li, 2015, Review on complement analysis method and the roles of glycosaminoglycans in the complement system, Carbohydr Polym, 134, 590, 10.1016/j.carbpol.2015.08.028 Harris, 2003, Effect of pegylation on pharmaceuticals, Nat Rev Drug Discovery, 2, 214, 10.1038/nrd1033 Owens, 2006, Opsonization, biodistribution, and pharmacokinetics of polymeric nanoparticles, Int J Pharm, 307, 93, 10.1016/j.ijpharm.2005.10.010 Dufort, 2011, Physico-chemical parameters that govern nanoparticles fate also dictate rules for their molecular evolution, Adv Drug Delivery Rev, 64, 179, 10.1016/j.addr.2011.09.009 Lv, 2012, Targeted delivery of insoluble cargo (Paclitaxel) by PEGylated chitosan nanoparticles grafted with Arg-Gly-Asp (RGD), Mol Pharmaceutics, 9, 1736, 10.1021/mp300051h Mustafa, 2016, Effect of PEG and water-soluble chitosan coating on moxifloxacin-loaded PLGA long-circulating nanoparticles, Drug Delivery Transl Res, 7, 27, 10.1007/s13346-016-0326-7 Fam, 2020, Stealth coating of nanoparticles in drug-delivery systems, Nanomaterials, 10, 787, 10.3390/nano10040787 Suk, 2016, PEGylation as a strategy for improving nanoparticle-based drug and gene delivery, Adv Drug Delivery Rev, 99, 28, 10.1016/j.addr.2015.09.012 Rampado, 2020, Recent advances in understanding the protein corona of nanoparticles and in the formulation of "stealthy" nanomaterials, Front Bioeng Biotechnol, 8, 10.3389/fbioe.2020.00166 Ovais, 2020, Recent advances in the analysis of nanoparticle-protein coronas, Nanomedicine, 15, 10.2217/nnm-2019-0381 Verhoef, 2014, Potential induction of anti-PEG antibodies and complement activation toward PEGylated therapeutics, Drug Discov. Today, 19, 1945, 10.1016/j.drudis.2014.08.015 Koide, 2010, T cell-independent B cell response is responsible for ABC phenomenon induced by repeated injection of PEGylated liposomes, Int J Pharm, 392, 218, 10.1016/j.ijpharm.2010.03.022 Ishida, 2013, Anti-polyethyleneglycol antibody response to PEGylated substances, Biol Pharm Bull, 36, 889, 10.1248/bpb.b13-00107 Garay, 2012, Antibodies against polyethylene glycol in healthy subjects and in patients treated with PEG-conjugated agents, Expert Opin Drug Delivery, 9, 1319, 10.1517/17425247.2012.720969 Kierstead, 2015, The effect of polymer backbone chemistry on the induction of the accelerated blood clearance in polymer modified liposomes, J Controlled Release, 213, 1, 10.1016/j.jconrel.2015.06.023 Kurniasih, 2015, Dendritic nanocarriers based on hyperbranched polymers, Chem Soc Rev, 44, 4145, 10.1039/C4CS00333K Zou, 2015, Nanocarriers with tunable surface properties to unblock bottlenecks in systemic drug and gene delivery, J Controlled Release, 214, 121, 10.1016/j.jconrel.2015.07.014 Woodle, 1994, New amphipatic polymer-lipid conjugates forming long-circulating reticuloendothelial system-evading liposomes, Bioconjugate Chem, 5, 493, 10.1021/bc00030a001 Koshkina, 2016, Tuning the surface of nanoparticles: impact of poly(2-ethyl-2-oxazoline) on protein adsorption in serum and cellular uptake, Macromol Biosci, 16, 1287, 10.1002/mabi.201600074 Lorson, 2018, Poly(2-oxazoline)s based biomaterials: a comprehensive and critical update, Biomaterials, 178, 204, 10.1016/j.biomaterials.2018.05.022 Joseph, 2017, Investigations on pharmacokinetics and biodistribution of polymeric and solid lipid nanoparticulate systems of atypical antipsychotic drug: effect of material used and surface modification, Drug Dev Commun, 43, 678 Li, 2009, Nanoparticles evading the reticuloendothelial system: role of the supported bilayer, Biochim Biophys Acta, 1788, 2259, 10.1016/j.bbamem.2009.06.022 Hans, 2002, Biodegradable nanoparticles for drug delivery and targeting, Curr Opin Solid State Mater Sci, 6, 319, 10.1016/S1359-0286(02)00117-1 Gaur, 2000, Biodistribution of fluoresceinated dextran using novel nanoparticles evading reticuloendothelial system, Int J Pharm, 202, 1, 10.1016/S0378-5173(99)00447-0 Kim, 2017, Co-coating of receptor-targeted drug nanocarriers with anti-phagocytic moieties enhances specific tissue uptake versus non-specific phagocytic clearance, Biomaterials, 147, 14, 10.1016/j.biomaterials.2017.08.045 Lee, 2019, Red blood cell membrane bioengineered Zr-89 labelled hollow mesoporous silica nanosphere for overcoming phagocytosis, Sci Rep, 9, 7419, 10.1038/s41598-019-43969-y Hu, 2011, Erythrocyte membrane-camouflaged polymeric nanoparticles as a biomimetic delivery platform, Proc Natl Acad Sci USA, 108, 10980, 10.1073/pnas.1106634108 Anselmo, 2013, Delivering nanoparticles to lungs while avoiding liver and spleen through adsorption on red blood cells, ACS Nano, 7, 11129, 10.1021/nn404853z Larsen, 2009, Size-dependent accumulation of pegylated silane-coated magnetic iron oxide nanoparticles in murine tumors, ACS Nano, 3, 1947, 10.1021/nn900330m Xue, 2018, Synthesis, physico-chemical characterization, and antioxidant effect of PEGylated cerium oxide nanoparticles, Drug Delivery Transl Res, 8, 357, 10.1007/s13346-017-0396-1 Schädlich, 2011, Tumor accumulation of NIR fluorescent PEG-PLA nanoparticles: impact of particle size and human xenograft tumor model, ACS Nano, 5, 8710, 10.1021/nn2026353 Maurizi, 2015, Influence of surface charge and polymer coating on internalization and biodistribution of polyethylene glycol-modified iron oxide nanoparticles, J Biomed Nanotechnol, 11, 126, 10.1166/jbn.2015.1996 Pang, 2016, Demonstrating approaches to chemically modify the surface of Ag nanoparticles in order to influence their cytotoxicity and biodistribution after single dose acute intravenous administration, Nanotoxicology, 10, 129 Zhang, 2015, Effects of PEGylated paclitaxel nanocrystals on breast cancer and its lung metastasis, Nanoscale, 7, 10790, 10.1039/C4NR07450E Yu, 2012, Positive surface charge enhances selective cellular uptake and anticancer efficacy of selenium nanoparticles, Inorg Chem, 51, 8956, 10.1021/ic301050v Zhao, 2017, A comparison between sphere and rod nanoparticles regarding their in vivo biological behavior and pharmacokinetics, Sci Rep, 7, 4131, 10.1038/s41598-017-03834-2