Single-run UHPLC-MS/MS method for simultaneous quantification of endogenous steroids and their phase II metabolites in serum for anti-doping purposes
Tài liệu tham khảo
Ponzetto, 2016, Methods for doping detection, Front. Horm. Res., 47, 153, 10.1159/000445177
Mullen, 2018, Sensitivity of doping biomarkers after administration of a single dose testosterone gel, Drug Test. Anal., 10, 839, 10.1002/dta.2341
Miller, 2016, Intranasal delivery of Natesto® testosterone gel and its effects on doping markers, Drug Test. Anal., 8, 1197, 10.1002/dta.2106
Badoud, 2013, Profiling of steroid metabolites after transdermal and oral administration of testosterone by ultra-high pressure liquid chromatography coupled to quadrupole time-of-flight mass spectrometry, J. Steroid Biochem. Mol. Biol., 138, 222, 10.1016/j.jsbmb.2013.05.018
Schulze, 2008, Doping test results dependent on genotype of uridine diphospho-glucuronosyl transferase 2B17, the major enzyme for testosterone glucuronidation, J. Clin. Endocrinol. Metab., 93, 2500, 10.1210/jc.2008-0218
Kuuranne, 2014, Confounding factors and genetic polymorphism in the evaluation of individual steroid profiling, Br. J. Sports Med., 48, 848, 10.1136/bjsports-2014-093510
Piper, 2021, Current insights into the steroidal module of the athlete biological Passport, Int. J. Sports Med., 42, 863, 10.1055/a-1481-8683
Mazzarino, 2021, Effects of the administration of miconazole by different routes on the biomarkers of the "steroidal module" of the Athlete Biological Passport, Drug Test. Anal., 13, 1712, 10.1002/dta.3121
Stoll, 2020, Influence of indomethacin on steroid metabolism: endocrine disruption and confounding effects in urinary steroid profiling of anti-doping analyses, Metabolites, 10, 463, 10.3390/metabo10110463
Schulze, 2021, Re-evaluation of combined ((ES/EG)/(TS/TG)) ratio as a marker of testosterone intake in men, Drug Test. Anal., 13, 1576, 10.1002/dta.3045
De Wilde, 2020, Steroid profiling in urine of intact glucuronidated and sulfated steroids using liquid chromatography-mass spectrometry, J. Chromatogr. A, 1624, 10.1016/j.chroma.2020.461231
Saad, 2019, Population reference ranges of urinary endogenous sulfate steroids concentrations and ratios as complement to the steroid profile in sports antidoping, Steroids, 152, 10.1016/j.steroids.2019.108477
Esquivel, 2019, Evaluation of sulfate metabolites as markers of intramuscular testosterone administration in Caucasian and Asian populations, Drug Test. Anal., 11, 1218, 10.1002/dta.2598
Bae, 2019, Reference intervals of nine steroid hormones over the life-span analyzed by LC-MS/MS: effect of age, gender, puberty, and oral contraceptives, J. Steroid Biochem. Mol. Biol., 193, 10.1016/j.jsbmb.2019.105409
Faiss, 2019, Fighting doping in elite sports: blood for all tests, Front Sports Act Living, 1, 30, 10.3389/fspor.2019.00030
Handelsman, 2019, Detection of testosterone doping in female athletes, Drug Test. Anal., 11, 1566, 10.1002/dta.2689
Ponzetto, 2016, Longitudinal monitoring of endogenous steroids in human serum by UHPLC-MS/MS as a tool to detect testosterone abuse in sports, Anal. Bioanal. Chem., 408, 705, 10.1007/s00216-015-9185-1
Ponzetto, 2019, Steroidomics for highlighting novel serum biomarkers of testosterone doping, Bioanalysis, 11, 1171, 10.4155/bio-2019-0079
Knutsson, 2021, Disposition of urinary and serum steroid metabolites in response to testosterone administration in healthy women, J. Clin. Endocrinol. Metab., 106, 697, 10.1210/clinem/dgaa904
Salamin, 2021, Longitudinal evaluation of multiple biomarkers for the detection of testosterone gel administration in women with normal menstrual cycle, Drug Test. Anal.
Eklund, 2021, Urinary steroid profile in elite female athletes in relation to serum androgens and in comparison with untrained controls, Front. Physiol., 12, 10.3389/fphys.2021.702305
Salamin, 2021, Steroid profiling by UHPLC-MS/MS in dried blood spots collected from healthy women with and without testosterone gel administration, J. Pharm. Biomed. Anal., 204, 10.1016/j.jpba.2021.114280
Elmongy, 2020, Development and validation of a UHPLC-HRMS method for the simultaneous determination of the endogenous anabolic androgenic steroids in human serum, J. Chromatogr. A, 1613, 10.1016/j.chroma.2019.460686
Nair, 2021, Evaluation of blood parameters by linear discriminant models for the detection of testosterone administration, Drug Test. Anal., 13, 1270, 10.1002/dta.3017
Piper, 2021, Carbon isotope ratios of endogenous steroids found in human serum-method development, validation, and reference population-derived thresholds, Anal. Bioanal. Chem., 413, 5655, 10.1007/s00216-021-03439-9
2017
Matuszewski, 2003, Strategies for the assessment of matrix effect in quantitative bioanalytical methods based on HPLC-MS/MS, Anal. Chem., 75, 3019, 10.1021/ac020361s
2021
Salamin, 2020, Development and validation of an UHPLC-MS/MS method for extended serum steroid profiling in female populations, Bioanalysis, 12, 753, 10.4155/bio-2020-0046
Esquivel, 2018, Direct quantitation of endogenous steroid sulfates in human urine by liquid chromatography-electrospray tandem mass spectrometry, Drug Test. Anal., 10, 1734, 10.1002/dta.2413
Bae, 2019, Reference intervals of nine steroid hormones over the life-span analyzed by LC-MS/MS: effect of age, gender, puberty, and oral contraceptives, J. Steroid Biochem. Mol. Biol., 193, 10.1016/j.jsbmb.2019.105409
Mezzullo, 2020, Female and male serum reference intervals for challenging sex and precursor steroids by liquid chromatography - tandem mass spectrometry, J. Steroid Biochem. Mol. Biol., 197, 10.1016/j.jsbmb.2019.105538
Miller, 2019, Congenital adrenal Hyperplasia: time to replace 17OHP with 21-deoxycortisol, Horm Res Paediatr, 91, 416, 10.1159/000501396
Gupta, 2010, Deoxycorticosterone producing tumor as a cause of resistant hypertension, Case Rep Med, 10.1155/2010/372719
Friedrich, 2008, Reference ranges for serum dehydroepiandrosterone sulfate and testosterone in adult men, J. Androl., 29, 610, 10.2164/jandrol.108.005561
Van der Veen, 2019, Development and validation of a LC-MS/MS method for the establishment of reference intervals and biological variation for five plasma steroid hormones, Clin. Biochem., 68, 15, 10.1016/j.clinbiochem.2019.03.013
Bae, 2019, Reference intervals of nine steroid hormones over the life-span analyzed by LC-MS/MS: effect of age, gender, puberty, and oral contraceptives, Steroid Biochem Mol Biol, 193, 10.1016/j.jsbmb.2019.105409
Fabregat-Cabello, 2019, Establishment of reference intervals for serum concentrations of androstanediol glucuronide by a newly developed LC-MS/MS method, Steroids, 143, 62, 10.1016/j.steroids.2018.12.008
Sanchez-Guijo, 2015, Simultaneous quantification of cholesterol sulfate, androgen sulfates, and progestagen sulfates in human serum by LC-MS/MS, J. Lipid Res., 56, 1843, 10.1194/jlr.D061499
Sanchez-Guijo, 2016, Role of steroid sulfatase in steroid homeostasis and characterization of the sulfated steroid pathway: evidence from steroid sulfatase deficiency, Mol. Cell. Endocrinol., 437, 142, 10.1016/j.mce.2016.08.019