Single bead investigation of a clinical drug delivery system – A novel release mechanism

Dosio, 2016, Hyaluronic acid for anticancer drug and nucleic acid delivery, Adv. Drug Deliv. Rev., 97, 204, 10.1016/j.addr.2015.11.011 Peppas, 2000, Hydrogels in pharmaceutical formulations, Eur. J. Pharm. Biopharm., 50, 27, 10.1016/S0939-6411(00)00090-4 Abismaı̈L, 1999, Emulsification by ultrasound: drop size distribution and stability, Ultrason. Sonochem., 6, 75, 10.1016/S1350-4177(98)00027-3 Park, 2014, Controlled drug delivery systems: past forward and future back, J. Control. Release, 190, 3, 10.1016/j.jconrel.2014.03.054 Hoare, 2008, Hydrogels in drug delivery: progress and challenges, Polymer, 49, 1993, 10.1016/j.polymer.2008.01.027 Attwood, 1995, The mode of association of amphiphilic drugs in aqueous solution, Adv. Colloid Interf. Sci., 55, 271, 10.1016/0001-8686(94)00228-5 Barbosa, 2008, Self-assembling of phenothiazine compounds investigated by small-angle X-ray scattering and electron paramagnetic resonance spectroscopy, J. Phys. Chem. B, 112, 4261, 10.1021/jp710332t Perez-Villar, 1993, Small-angle neutron scattering studies of chlorpromazine micelles in aqueous solutions, J. Phys. Chem., 97, 5149, 10.1021/j100121a050 Li, 1998, Doxorubicin physical state in solution and inside liposomes loaded via a pH gradient, Biochimica et Biophysica Acta (BBA)-Biomembranes, 1415, 23, 10.1016/S0005-2736(98)00175-8 Tasca, 2018, A stereochemically driven supramolecular polymerisation, Chem Eur J, 24, 8195, 10.1002/chem.201800644 Hansson, 2006, Interaction between polyelectrolyte gels and surfactants of opposite charge, Curr. Opin. Colloid Interface Sci., 11, 351, 10.1016/j.cocis.2006.11.005 Hansson, 1998, Self-assembly of ionic surfactant in cross-linked polyelectrolyte gel of opposite charge. A physical model for highly charged systems, Langmuir, 14, 2269, 10.1021/la971165x Hansson, 2009, Surfactant self-assembly in oppositely charged polymer networks. Theory, J. Phys. Chem. B, 113, 12903, 10.1021/jp904866t Khokhlov, 1992, Collapse of polyelectrolyte networks induced by their interaction with an oppositely charged surfactant. Theory, Macromolecular Theory Simulations, 1, 105, 10.1002/mats.1992.040010301 Gernandt, 2015, Hysteresis in the surfactant-induced volume transition of hydrogels, J. Phys. Chem. B, 119, 1717, 10.1021/jp5087416 Gernandt, 2016, Surfactant-induced core/shell phase equilibrium in hydrogels, J. Chem. Phys, 144, 10.1063/1.4941326 Andersson, 2017, Phase behavior of salt-free polyelectrolyte gel–surfactant systems, J. Phys. Chem. B, 121, 6064, 10.1021/acs.jpcb.7b02215 Lewis, 2007, Doxorubicin eluting beads – 1: effects of drug loading on bead characteristics and drug distribution, J. Mater. Sci. Mater. Med, 18, 1691, 10.1007/s10856-007-3068-8 Lewis, 2006, DC bead: in vitro characterization of a drug-delivery device for transarterial chemoembolization, J. Vasc. Interv. Radiol., 17, 335, 10.1097/01.RVI.0000195323.46152.B3 Lilienberg, 2017, In vivo drug delivery performance of lipiodol-based emulsion or drug-eluting beads in patients with hepatocellular carcinoma, Mol. Pharm., 14, 448, 10.1021/acs.molpharmaceut.6b00886 Biondi, 2012, New insights into the mechanisms of the interactions between doxorubicin and the ion-exchange hydrogel DC Bead for use in transarterial chemoembolization (TACE), J. Biomater. Sci. Polymer Edition, 23, 333, 10.1163/092050610X551934 Ahnfelt, 2016, In vitro release mechanisms of doxorubicin from a clinical bead drug-delivery system, J. Pharm. Sci., 105, 3387, 10.1016/j.xphs.2016.08.011 Fülöp, 2013, A permeation method for detection of self-aggregation of doxorubicin in aqueous environment, Int. J. Pharm., 454, 559, 10.1016/j.ijpharm.2013.06.058 Agrawal, 2009, Studies on self-aggregation of anthracycline drugs by restrained molecular dynamics approach using nuclear magnetic resonance spectroscopy supported by absorption, fluorescence, diffusion ordered spectroscopy and mass spectrometry, Eur. J. Med. Chem., 44, 1437, 10.1016/j.ejmech.2008.09.037 Csuhai, 2015, Determination of key parameters for a mechanism-based model to predict doxorubicin release from actively loaded liposomes, J. Pharm. Sci., 104, 1087, 10.1002/jps.24307 Nilsson, 2005, Ion-exchange controls the kinetics of deswelling of polyelectrolyte microgels in solutions of oppositely charged surfactant, J. Phys. Chem. B, 109, 23843, 10.1021/jp054835d Jidheden, 2016, Single microgels in core–shell equilibrium: a novel method for limited volume studies, J. Phys. Chem. B, 120, 10030, 10.1021/acs.jpcb.6b06086 Frenning, 2017, Computational fluid dynamics (CFD) studies of a miniaturized dissolution system, Int. J. Pharm., 521, 274, 10.1016/j.ijpharm.2017.01.072 Bijlani, 2007, Monitoring ibuprofen release from multiparticulates: in situ fiber-optic technique versus the HPLC method: a technical note, AAPS PharmSciTech, 8, E9, 10.1208/pt0803052 Coulson, 1996 Cornellas, 2011, Self-aggregation and antimicrobial activity of imidazolium and pyridinium based ionic liquids in aqueous solution, J. Colloid Interface Sci., 355, 164, 10.1016/j.jcis.2010.11.063 Hansson, 2009, Phase behavior of aqueous polyion–surfactant ion complex salts: a theoretical analysis, J. Colloid Interface Sci., 332, 183, 10.1016/j.jcis.2008.12.011 Göransson, 2003, Shrinking kinetics of polyacrylate gels in surfactant solution, J. Phys. Chem. B, 107, 9203, 10.1021/jp027583e Helfferich, 1962 Corry, 2003, Dielectric self-energy in Poisson-Boltzmann and Poisson-Nernst-Planck models of ion channels, Biophys. J., 84, 3594, 10.1016/S0006-3495(03)75091-7 Leaist, 1986, Interdiffusion of acids and bases• HCl and NaOH in aqueous solution, Can. J. Chem., 64, 1007, 10.1139/v86-169 Lide, 1993 Hansson, 2000, Determination of micellar aggregation numbers in dilute surfactant systems with the fluorescence quenching method, J. Phys. Chem. B, 104, 3496, 10.1021/jp992444r Brumleve, 1978, Numerical solution of the Nernst-Planck and Poisson equation system with applications to membrane electrochemistry and solid state physics, J. Electroanal. Chem. Interfacial Electrochem., 90, 1, 10.1016/S0022-0728(78)80137-5 Khandurina, 1994, Interaction of cross-linked polyelectrolytes with oppositely charged surfactants, Polymer Sci, 36, 184 Khokhlov, 1994, Supramolecular structures and conformational transitions in polyelectrolyte gels, 69 Nordling, 1982, 1982 Biondi, 2013, Investigation of the mechanisms governing doxorubicin and irinotecan release from drug-eluting beads: mathematical modeling and experimental verification, J. Mater. Sci. Mater. Med, 24, 2359, 10.1007/s10856-013-4992-4 Kiser, 2000, Lipid-coated microgels for the triggered release of doxorubicin, J. Control. Release, 68, 9, 10.1016/S0168-3659(00)00236-4 Kung, 1993, Fourier transform infrared spectroscopic study of the adsorption of cetyltrimethylammonium bromide and cetylpyridinium chloride on silica, Langmuir, 9, 263, 10.1021/la00025a050 Israelachvili, 2011 Higuchi, 1961, Rate of release of medicaments from ointment bases containing drugs in suspension, J. Pharm. Sci., 50, 874, 10.1002/jps.2600501018 Bramer, 2009, Implications of regular solution theory on the release mechanism of catanionic mixtures from gels, Colloids Surf. B: Biointerfaces, 71, 214, 10.1016/j.colsurfb.2009.02.008 Gonzalez, 2008, Doxorubicin eluting beads-2: methods for evaluating drug elution and in-vitro:in-vivo correlation, J. Mater. Sci. Mater. Med, 19, 767, 10.1007/s10856-006-0040-y Thakur, 2007, Investigation of the micellar growth of 1-dodecylpyridinium chloride in aqueous solution of phenol, J. Mol. Liq., 136, 83, 10.1016/j.molliq.2007.01.006 Schreier, 2000, Surface active drugs: self-association and interaction with membranes and surfactants. Physicochemical and biological aspects, Biochim. Biophys. Acta Biomembr., 1508, 210, 10.1016/S0304-4157(00)00012-5 Sjöberg, 1999, How interactions between drugs and agarose-carrageenan hydrogels influence the simultaneous transport of drugs, J. Control. Release, 59, 391, 10.1016/S0168-3659(99)00013-9 Chrzanowski, 1985, The pKa of butaclamol and the mode of butaclamol binding to central dopamine receptors, J. Med. Chem., 28, 399, 10.1021/jm00381a022 Manzo, 2006, Biowaiver monographs for immediate release solid oral dosage forms: amitriptyline hydrochloride, J. Pharm. Sci., 95, 966, 10.1002/jps.20615 Kabir-Ud-Din, 2013, Surface and micellar properties of some amphiphilic drugs in various salt solutions, Colloid J, 75, 170, 10.1134/S1061933X13020075 Naqvi, 2013, Kabir-ud-Din, adsorption and micellization behavior of cationic surfactants (Gemini and conventional)—amphiphilic drug systems, J. Solut. Chem., 42, 172, 10.1007/s10953-012-9936-y Saal, 2018, Can we estimate the critical micelle concentration of amphiphilic drug bases from molecular connectivity indices?, Pharm. Dev. Technol., 23, 211, 10.1080/10837450.2017.1316288 Dalmark, 1981, A Fickian diffusion transport process with features of transport catalysis. Doxorubicin transport in human red blood cells, J. General Physiol, 78, 349, 10.1085/jgp.78.4.349