Simvastatin treatment partially prevents ovariectomy-induced bone loss while increasing cortical bone formation
Tài liệu tham khảo
Rogers, 2000, Statins: lower lipids and better bones?, Nat. Med., 6, 21, 10.1038/71484
Mundy, 1999, Stimulation of bone formation in vitro and in rodents by statins, Science, 286, 1946, 10.1126/science.286.5446.1946
Oxlund, 1999, Simvastatin given per orally increases the cortical bone formation rate in adult rats, J. Bone Miner. Res., 14, S313
Oxlund, 2000, Simvastatin given per orally to adult rats increases the compressive strength of vertebral bodies, J. Bone Miner. Res., 15, S549
Oxlund, 2001, Statin given per orally to adult rats increases cancellous bone mass and compressive strength, Calcif. Tissue Int., 69, 299, 10.1007/s00223-001-2027-5
Wilkie, 2000, Cerivastatin increases cortical bone formation in OVX rats, J. Bone Miner. Res., 15, S549
Masarachia, 2001, Effect of statins on bone mass and turnover in ovariectomized rats, J. Bone Miner. Res., 16, S295
Skoglund, 2002, Simvastatin improves fracture healing in mice, J. Bone Miner. Res., 17, 2004, 10.1359/jbmr.2002.17.11.2004
Gasser, 2001, Fluvastatin and cerivastatin are not anabolic for bone after local or systemic administration of non-toxic doses in mice and rats, J. Bone Miner. Res., 16, S295
Banu, 2002, Effects of cerivastatin and parathyroid hormone on the lumbar vertebra of aging male Sprague–Dawley rats, Bone, 31, 173, 10.1016/S8756-3282(02)00803-7
Yao, 2001, Simvastatin did not prevent bone loss in ovariectomized rats, J. Bone Miner. Res., 16, S294
Maritz, 2001, Effect of statins on bone mineral density and bone histomorphometry in rodents, Arterioscler. Thromb. Vasc. Biol., 21, 1636, 10.1161/hq1001.097781
Gutierrez, 2000, Dermal application of lovastatin to rats causes greater increases in bone formation and plasma concentrations than when administered by oral gavage, J. Bone Miner. Res., 15, S427
Mosekilde, 1998, Growth hormone increases vertebral and femoral bone strength in osteopenic, ovariectomized, aged rats in a dose-dependent and site-specific manner, Bone, 23, 343, 10.1016/S8756-3282(98)00107-0
Zhou, 2003, Anabolic action of parathyroid hormone on cortical and cancellous bone differs between axial and appendicular skeletal sites in mice, Bone, 32, 513, 10.1016/S8756-3282(03)00057-7
Bak, 1989, The effect of aging on fracture healing in the rat, Calcif. Tissue Int., 45, 292, 10.1007/BF02556022
Turner, 1993, Basic biomechanical measurements of bone: a tutorial, Bone, 14, 595, 10.1016/8756-3282(93)90081-K
Andreassen, 1995, Growth hormone stimulates bone formation and strength of cortical bone in aged rats, J. Bone Miner. Res., 10, 1057, 10.1002/jbmr.5650100710
Oxlund, 1998, Growth hormone and mild exercise in combination markedly enhance cortical bone formation and strength in old rats, Endocrinology, 139, 1899, 10.1210/endo.139.4.5949
Andreassen, 1996, The influence of growth hormone on cancellous and cortical bone of the vertebral body in aged rats, J. Bone Miner. Res., 11, 1094, 10.1002/jbmr.5650110808
Parfitt, 1989, Surface specific bone remodeling in health and disease, 7
Oxlund, 1993, Parathyroid hormone (1–34) and (1–84) stimulate cortical bone formation both from periosteum and endosteum, Calcif. Tissue Int., 53, 394, 10.1007/BF03549782
Sokal, 1981, 242
Jiang, 2001, Effect of simvastatin on three-dimensional trabecular architecture of ovariectomized rats, J. Bone Miner. Res., 16, S296
Crawford, 2001, Statin increases cortical bone in young male rats by single, local administration but fails to restore bone in ovariectomized (OVX) rats by daily systemic administration, J. Bone Miner. Res., 16, S295
Sugiyama, 2000, Compactin and simvastatin, but not pravastatin, induce bone morphogenetic protein-2 in human osteosarcoma cells, Biochem. Biophys. Res Commun., 271, 688, 10.1006/bbrc.2000.2697
Philips, 2001, Compactin enhances osteogenesis in murine embryonic stem cells, Biochem. Biophys. Res. Commun., 284, 478, 10.1006/bbrc.2001.4987
Ohnaka, 2001, Pitavastatin enhanced BMP-2 and osteocalcin expression by inhibition of rho-associated kinase in human osteoblasts, Biochem. Biophys. Res Commun., 287, 337, 10.1006/bbrc.2001.5597
Maeda, 2003, Statins augment vascular endothelial growth factor expression in osteoblastic cells via inhibition of protein prenylation, Endocrinology, 144, 681, 10.1210/en.2002-220682
Staal, 2003, The ability of statins to inhibit bone resorption is directly related to their inhibitory effect on HMG-CoA reductase activity, J. Bone Miner. Res., 18, 88, 10.1359/jbmr.2003.18.1.88
Edwards, 2000, Oral statins and increased bone-mineral density in postmenopausal women, Lancet, 355, 2218, 10.1016/S0140-6736(00)02408-9
Edwards, 2001, Statins and bone: myth or reality?, Calcif. Tissue Int., 69, 63, 10.1007/s00223-001-2017-7
Funkhouser, 2002, Effect of HMG-CoA reductase inhibitors (statins) on bone mineral density, J. Clin. Densitom., 5, 151, 10.1385/JCD:5:2:151
Montagnani, 2003, Effect of simvastatin treatment on bone mineral density and bone turnover in hypercholesterolemic postmenopausal women: a 1-year longitudinal study, Bone, 32, 427, 10.1016/S8756-3282(03)00034-6
Watanabe, 2001, Effects of 1-year treatment with fluvastatin or pravastatin on bone, Am. J. Med., 110, 584, 10.1016/S0002-9343(01)00679-9
Chan, 2000, Inhibitors of hydroxymethylglutaryl-coenzyme A reductase and risk of fracture among older women, Lancet, 355, 2185, 10.1016/S0140-6736(00)02400-4
Meier, 2000, HMG-CoA reductase inhibitors and the risk of fractures, JAMA, 283, 3205, 10.1001/jama.283.24.3205
Wang, 2000, HMG-CoA reductase inhibitors and the risk of hip fractures in elderly patients, JAMA, 283, 3211, 10.1001/jama.283.24.3211
Coons, 2002, Hydroxymethylglutaryl-coenzyme A reductase inhibitors in osteoporosis management, Ann. Pharmacother., 36, 326, 10.1345/aph.1A071
Pasco, 2002, Statin use, bone mineral density, and fracture risk: Geelong osteoporosis study, Arch. Intern. Med., 162, 537, 10.1001/archinte.162.5.537
Sirola, 2002, Relation of statin use and bone loss: a prospective population-based cohort study in early postmenopausal women, Osteoporos. Int., 13, 537, 10.1007/s001980200070
Reid, 2001, Effect of pravastatin on frequency of fracture in the LIPID study: secondary analysis of a randomized controlled trial. Long-term intervention with pravastatin in ischaemic disease, Lancet, 357, 509, 10.1016/S0140-6736(00)04042-3