Simultaneous determination of betulinic acid, β-sitosterol and lupeol in fruits, leaves, root and stem bark of Dillenia pentagyna Roxb. by a validated high-performance thin-layer chromatography method

Akademiai Kiado Zrt. - Tập 34 Số 6 - Trang 531-542 - 2021
Hari Om Saxena1, S. S. Parihar2, Ganesh Pawar2
1Tropical Forest Research Institute
2NWFP Section, Silviculture, Forest Management and Agroforestry Division, Tropical Forest Research Institute, Jabalpur, India

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Tiwari SK, Krishnamurthy G, Pandey A, Goswami MP, Saini P (2016) Standardization of clonal macropropagation protocol of Dillenia pentagyna Roxb an important and endangered medicinal tree species through stem branch cuttings. J Biotechnol Biomater 6:222. https://doi.org/10.4172/2155-952X.1000222

Khanum A, Khan I, Ali A (2007) Ethnomedicine and human welfare, vol 4. Ukaaz Publications, Hyderabad, p 52

Khare CP (2007) Indian medicinal plants. Springer-Verlag, Berlin, p 214

Dubey PC, Sikarwar RLS, Khanna KK, Tiwari AP (2009) Ethnobotany of Dillenia pentagyna Roxb. In Vindhyna region of Madhya Pradesh. India Nat Prod Rad 8:546–548

Sikarwar RLS, Dubey PC, Tiwari AP (2016) Dillenia pentagyna Roxb. (Dilleniaceae) in central India: a plea for its conservation. Indian For 142 (7):649–653.

Nyman U, Joshi P, Madsen LB, Pedersen TB, Pinstrup M, Rajasekharan S, George V, Pushpangadan P (1998) Ethnomedical information and in vitro screening for angiotensin-converting enzyme inhibition of plants utilized as traditional medicines in Gujarat, Rajasthan and Kerala (India). J Ethnopharmacol 60(3):247–263. https://doi.org/10.1016/S0378-8741(97)00158-X

Chaubey S, Tewari RC, Kurele R, Keeta K, Kour GD (2015) Pharmacognostical evaluation of nagakesara used in different parts of India. Int J Ayur Pharm Res 3:46–51

Sharma HK, Chhangte L, Dolui AK (2001) Traditional medicinal plants in Mizoram, India. Fitoterapia 72:146–161. https://doi.org/10.1016/S0367-326X(00)00278-1

Yazan SL, Armania N (2014) Dillenia species: areview of the traditional uses, active constituents and pharmacological properties from pre-clinical studies. Pharm Biol 52(7):890–897. https://doi.org/10.3109/13880209.2013.872672

Singha AK, Bhattacharjee B, Ghosh R, De U, Maiti D (2013) Antibacterial, anti-alpha glucosidase and antioxidant properties of Dillenia pentagyna Roxb. (Dilleniaceae). Asian J Pharm Clin Res 6(4):173–177.

Rosangkima G, Prasad SB (2004) Antitumour activity of some plants from Meghalaya and Mizoram against murine ascites Dalton’s lymphoma. Indian J Exp Biol 42:981–988

Rosangkima G, Prasad SB (2008) Inhibitory effect of Dillenia pentagyna stem bark extract on cisplatin and benzo[a]pyrene-induced mutagenicity. Can J Appl Sci 2:381–387

Haque ME, Islam MN, Hossain M, Mohamad AU, Karim MF, Rahman MA (2008) Antimicrobial and cytotoxic activities of Dillenia pentagyna. Dhaka University J Pharm Sci 7(1):103–105

Ghimire K, Bastakoti RR (2009) Ethnomedicinal knowledge and healthcare practices among the Tharus of Nawalparasi district in central Nepal. For Ecol Manage 257:2066–2072. https://doi.org/10.1016/j.foreco.2009.01.039

Gandhi D, Mehta P (2013) Validated high-performance thin-layer chromatographic method for the quantification of betulinic acid from two Indian plants of the species Dillenia and Ziziphus. J Planar Chromatogr 26(4):331–335. https://doi.org/10.1556/jpc.26.2013.4.7

Cichewicz RH, Kouzi SA (2004) Chemistry, biological activity, and chemotherapeutic potential of betulinic acid for the prevention and treatment of cancer and HIV infection. Med Res Rev 24(1):90–114. https://doi.org/10.1002/med.10053

Yogeeswari P, Sriram D (2005) Betulinic acid and its derivatives: a review on their biological properties. Curr Med Chem 12(6):657–666. https://doi.org/10.2174/0929867053202214

Fulda S (2008) Betulinic acid for cancer treatment and prevention. Int J Mol Sci 9(6):1096–1107. https://doi.org/10.3390/ijms9061096

Ambavade SD, Misar AV, Ambavade PD (2014) Pharmacological, nutritional, and analytical aspects of β-sitosterol: a review. Orient Pharm Exp Med 14(3):193–211. https://doi.org/10.1007/s13596-014-0151-9

Ahmad H, Sehgal S, Mishra A, Rajiv G, Shubhini SA (2012) TLC Detection of β-sitosterol in Michelia champaca L. Leaves and Stem Bark and its Determination by HPTLC. Phcog J 4(27):45–55. https://doi.org/10.5530/pj.2012.27.8

Margareth BCG, Miranda JS (2009) Biological activities of lupeol. Int J Biomed Pharm Sci 3(1):46–66

Saxena HO, Mohan B, Kakkar A, Pawar G (2017) Chemotypic Variation of Lupeol in Roots of Hemidesmus indicus (L.) R. Br. from Different Agroclimatic Regions of Madhya Pradesh State of India. Curr Tradit Med 3(1):29–37. https://doi.org/10.2174/2215083802666161104154139

International Conference on Harmonization (ICH) (2005) Guideline Q2 (R1): validation of analytical procedures: text and methodology. Geneva, October 1994. https://database.ich.org/sites/default/files/Q2%28R1%29%20Guideline.pdf