Silk fibroin as biomaterial for bone tissue engineering
Tóm tắt
Từ khóa
Tài liệu tham khảo
Griffith, 2006, Capturing complex 3D tissue physiology in vitro, Nat. Rev. Mol. Cell Biol., 7, 211, 10.1038/nrm1858
Elliott, 2011, A review of three-dimensional in vitro tissue models for drug discovery and transport studies, J. Pharm. Sci., 100, 59, 10.1002/jps.22257
Bose, 2012, Recent advances in bone tissue engineering scaffolds, Trends Biotechnol., 30, 546, 10.1016/j.tibtech.2012.07.005
Wu, 2014, Biomimetic porous scaffolds for bone tissue engineering, Mater. Sci. Eng. R-Rep., 80, 1, 10.1016/j.mser.2014.04.001
Kasoju, 2012, Silk fibroin in tissue engineering, Adv. Healthc. Mater., 1, 393, 10.1002/adhm.201200097
Buckwalter, 1996, Bone biology. I: Structure, blood supply, cells, matrix, and mineralization, Instr. Course Lect., 45, 371
Roach, 1994, Why does bone matrix contain non-collagenous proteins? The possible roles of osteocalcin, osteonectin, osteopontin and bone sialoprotein in bone mineralisation and resorption, Cell Biol. Int., 18, 617, 10.1006/cbir.1994.1088
Olszta, 2007, Bone structure and formation: a new perspective, Mater. Sci. Eng. R-Rep., 58, 77, 10.1016/j.mser.2007.05.001
Watt, 2000, Out of Eden: stem cells and their niches, Science, 287, 1427, 10.1126/science.287.5457.1427
Engler, 2006, Matrix elasticity directs stem cell lineage specification, Cell, 126, 677, 10.1016/j.cell.2006.06.044
Watt, 2013, Role of the extracellular matrix in regulating stem cell fate, Nat. Rev. Mol. Cell Biol., 14, 467, 10.1038/nrm3620
Taichman, 2004, Blood and bone: two tissues whose fates are intertwined to create the hematopoietic stem-cell niche, Blood, 105, 2631, 10.1182/blood-2004-06-2480
Techawiboonwong, 2008, Cortical bone water: in vivo quantification with ultrashort echo-time MR imaging, Radiology, 248, 824, 10.1148/radiol.2482071995
Ehrlich, 2002, Mechanical strain and bone cell function: a review, Osteoporos. Int., 688, 10.1007/s001980200095
Suda, 1992, Modulation of osteoclast differentiation, Endocr. Rev., 13, 66
Väänänen, 2000, The cell biology of osteoclast function, J. Cell Sci., 113, 377, 10.1242/jcs.113.3.377
Hsieh, 2002, In vivo fatigue loading of the rat ulna induces both bone formation and resorption and leads to time-related changes in bone mechanical properties and density, J. Orthop. Res., 20, 764, 10.1016/S0736-0266(01)00161-9
Boyce, 2009, Osteoclasts have multiple roles in bone in addition to bone resorption, Crit. Rev. Eukaryot. Gene Expr., 19, 171, 10.1615/CritRevEukarGeneExpr.v19.i3.10
Robling, 2006, Biomechanical and molecular regulation of bone remodeling, Annu. Rev. Biomed. Eng., 8, 455, 10.1146/annurev.bioeng.8.061505.095721
Franz-Odendaal, 2006, Buried alive: how osteoblasts become osteocytes, Dev. Dyn., 235, 176, 10.1002/dvdy.20603
Dallas, 2010, Dynamics of the transition from osteoblast to osteocyte, Ann. N. Y. Acad. Sci., 1192, 437, 10.1111/j.1749-6632.2009.05246.x
Lanyon, 1993, Osteocytes, strain detection, bone modeling and remodeling, Calcif. Tissue Int., 53, S102, 10.1007/BF01673415
Burger, 1999, Mechanotransduction in bone – role of the lacuno-canalicular network, FASEB J., 13, S101
Santos, 2011, Mechanical loading stimulates BMP7, but not BMP2, production by osteocytes, Calcif. Tissue Int., 89, 318, 10.1007/s00223-011-9521-1
Bonewald, 2008, Osteocytes, mechanosensing and Wnt signaling, Bone, 42, 606, 10.1016/j.bone.2007.12.224
Klein-Nulend, 1995, Pulsating fluid flow increases nitric oxide (NO) synthesis by osteocytes but not periosteal fibroblasts–correlation with prostaglandin upregulation, Biochem. Biophys. Res. Commun., 217, 640, 10.1006/bbrc.1995.2822
Santos, 2009, Pulsating fluid flow modulates gene expression of proteins involved in Wnt signaling pathways in osteocytes, J. Orthop. Res., 27, 1280, 10.1002/jor.20888
Robling, 2008, Mechanical stimulation of bone in vivo reduces osteocyte expression of Sost/sclerostin, J. Biol. Chem., 283, 5866, 10.1074/jbc.M705092200
Klein-Nulend, 2012, Mechanical loading and how it affects bone cells: the role of the osteocyte cytoskeleton in maintaining our skeleton, Eur. Cell Mater., 24, 278, 10.22203/eCM.v024a20
Pittenger, 1999, Multilineage potential of adult human mesenchymal stem cells, Science, 284, 143, 10.1126/science.284.5411.143
Wang, 2013, Role of mesenchymal stem cells in bone regeneration and fracture repair: a review, Int. Orthop., 37, 2491, 10.1007/s00264-013-2059-2
Hass, 2011, Different populations and sources of human mesenchymal stem cells (MSC): a comparison of adult and neonatal tissue-derived MSC, Cell Commun. Signal., 9, 12, 10.1186/1478-811X-9-12
Wagner, 2008, Replicative senescence of mesenchymal stem cells: a continuous and organized process, PLoS ONE, 3, e2213, 10.1371/journal.pone.0002213
Ghibaudo, 2008, Traction forces and rigidity sensing regulate cell functions, Soft Matter, 4, 1836, 10.1039/b804103b
McMurray, 2013, Surface topography regulates wnt signaling through control of primary cilia structure in mesenchymal stem cells, Sci. Rep., 3
Dalby, 2007, The control of human mesenchymal cell differentiation using nanoscale symmetry and disorder, Nat. Mater., 6, 997, 10.1038/nmat2013
Liu, 2007, Endothelial cell migration on surface-density gradients of fibronectin, VEGF, or both proteins, Langmuir, 23, 11168, 10.1021/la701435x
Won, 2014, Cell surface engineering to enhance mesenchymal stem cell migration toward an SDF-1 gradient, Biomaterials, 35, 5627, 10.1016/j.biomaterials.2014.03.070
Yavari, 2014, Bone regeneration performance of surface-treated porous titanium, Biomaterials, 35, 6172, 10.1016/j.biomaterials.2014.04.054
Unadkat, 2011, An algorithm-based topographical biomaterials library to instruct cell fate, Proc. Natl. Acad. Sci. U.S.A., 108, 16565, 10.1073/pnas.1109861108
Sutherland, 2010, Insect silk: one name, many materials, Annu. Rev. Entomol., 55, 171, 10.1146/annurev-ento-112408-085401
Mhuka, 2013, Chemical, structural and thermal properties of Gonometa postica silk fibroin, a potential biomaterial, Int. J. Biol. Macromol., 52, 305, 10.1016/j.ijbiomac.2012.09.010
Teulé, 2012, Silkworms transformed with chimeric silkworm/spider silk genes spin composite silk fibers with improved mechanical properties, Proc. Natl. Acad. Sci., 109, 923, 10.1073/pnas.1109420109
Zaoming, 2015, Partial characterization of the silk allergens in mulberry silk extract, J. Allergy Clin. Immunol., 97, 210, 10.1016/S0091-6749(96)80327-7
Soong, 1984, Adverse reactions to virgin silk sutures in cataract surgery, Ophthalmology, 91, 479, 10.1016/S0161-6420(84)34273-7
Wen, 1990, Silk-induced asthma in children: a report of 64 cases, Ann. Allergy, 65, 375
Hollander, 1994, Interstitial cystitis and silk allergy, Med. Hypotheses, 43, 155, 10.1016/0306-9877(94)90142-2
Chirila, 2013, Evaluation of silk sericin as a biomaterial: in vitro growth of human corneal limbal epithelial cells on Bombyx mori sericin membranes, Prog. Biomater., 2, 10, 10.1186/2194-0517-2-14
Aramwit, 2009, Monitoring of inflammatory mediators induced by silk sericin, J. Biosci. Bioeng., 107, 556, 10.1016/j.jbiosc.2008.12.012
Inoue, 2000, Silk fibroin of Bombyx mori is secreted, assembling a high molecular mass elementary unit consisting of H-chain, L-chain, and P25, with a 6:6:1 molar ratio, J. Biol. Chem., 275, 40517, 10.1074/jbc.M006897200
Tanaka, 1999, Hydrophobic interaction of P25, containing Asn-linked oligosaccharide chains, with the H-L complex of silk fibroin produced by Bombyx mori, Insect Biochem. Mol. Biol., 29, 269, 10.1016/S0965-1748(98)00135-0
Zhou, 2001, Silk fibroin: structural implications of a remarkable amino acid sequence, Proteins Struct. Funct. Bioinform., 44, 119, 10.1002/prot.1078
Hayashi, 1999, Hypotheses that correlate the sequence, structure, and mechanical properties of spider silk proteins, Int. J. Biol. Macromol., 24, 271, 10.1016/S0141-8130(98)00089-0
Huemmerich, 2006, Processing and modification of films made from recombinant spider silk proteins, Appl. Phys. A Mater. Sci. Process., 82, 219, 10.1007/s00339-005-3428-5
Keten, 2010, Nanoconfinement controls stiffness, strength and mechanical toughness of β-sheet crystals in silk, Nat. Mater., 9, 359, 10.1038/nmat2704
Hedhammar, 2008, Structural properties of recombinant nonrepetitive and repetitive parts of major ampullate spidroin 1 from Euprosthenops australis: implications for fiber formation, Biochemistry, 47, 3407, 10.1021/bi702432y
Sponner, 2007, Composition and hierarchical organisation of a spider silk, PLoS ONE, 2, e998, 10.1371/journal.pone.0000998
Gosline, 1999, The mechanical design of spider silks: from fibroin sequence to mechanical function, J. Exp. Biol., 202, 3295, 10.1242/jeb.202.23.3295
Pérez-Rigueiro, 2001, Tensile properties of silkworm silk obtained by forced silking, J. Appl. Polym. Sci., 82, 1928, 10.1002/app.2038
Pérez-Rigueiro, 2002, Effect of degumming on the tensile properties of silkworm (Bombyx mori) silk fiber, J. Appl. Polym. Sci., 84, 1431, 10.1002/app.10366
Minoura, 1995, Attachment and growth of fibroblast cells on silk fibroin, Biochem. Biophys. Res. Commun., 208, 511, 10.1006/bbrc.1995.1368
Santin, 1999, In vitro evaluation of the inflammatory potential of the silk fibroin, J. Biomed. Mater. Res., 46, 382, 10.1002/(SICI)1097-4636(19990905)46:3<382::AID-JBM11>3.0.CO;2-R
Sakabe, 1989, In vivo blood compatibility of regenerated silk fibroin, Sen’i Gakkaishi, 45, 487, 10.2115/fiber.45.11_487
Meinel, 2005, The inflammatory responses to silk films in vitro and in vivo, Biomaterials, 26, 147, 10.1016/j.biomaterials.2004.02.047
Padol, 2011, Safety evaluation of silk protein film (a novel wound healing agent) in terms of acute dermal toxicity, acute dermal irritation and skin sensitization, Toxicol Int, 18, 17, 10.4103/0971-6580.75847
Wharram, 2010, Electrospun silk material systems for wound healing, Macromol. Biosci., 10, 246, 10.1002/mabi.200900274
Li, 2003, Enzymatic degradation behavior of porous silk fibroin sheets, Biomaterials, 24, 357, 10.1016/S0142-9612(02)00326-5
Horan, 2005, In vitro degradation of silk fibroin, Biomaterials, 26, 3385, 10.1016/j.biomaterials.2004.09.020
Numata, 2010, Mechanism of enzymatic degradation of beta-sheet crystals, Biomaterials, 31, 2926, 10.1016/j.biomaterials.2009.12.026
Jin, 2005, Water-stable silk films with reduced β-sheet content, Adv. Funct. Mater., 15, 1241, 10.1002/adfm.200400405
Lu, 2010, Water-insoluble silk films with silk I structure, Acta Biomater., 6, 1380, 10.1016/j.actbio.2009.10.041
You, 2015, Comparison of the in vitro and in vivo degradations of silk fibroin scaffolds from mulberry and nonmulberry silkworms, Biomed. Mater., 10, 15003, 10.1088/1748-6041/10/1/015003
Huang, 2014, A quicker degradation rate is yielded by a novel kind of transgenic silk fibroin consisting of shortened silk fibroin heavy chains fused with matrix metalloproteinase cleavage sites, J. Mater. Sci. Med., 25, 1833, 10.1007/s10856-014-5220-6
Pritchard, 2011, Incorporation of proteinase inhibitors into silk-based delivery devices for enhanced control of degradation and drug release, Biomaterials, 32, 909, 10.1016/j.biomaterials.2010.09.055
Hutmacher, 2000, Scaffolds in tissue engineering bone and cartilage, Biomaterials, 21, 2529, 10.1016/S0142-9612(00)00121-6
Zhang, 2010, The effects of pore architecture in silk fibroin scaffolds on the growth and differentiation of mesenchymal stem cells expressing BMP7, Acta Biomater., 6, 3021, 10.1016/j.actbio.2010.02.030
Murphy, 2010, The effect of mean pore size on cell attachment, proliferation and migration in collagen-glycosaminoglycan scaffolds for bone tissue engineering, Biomaterials, 31, 461, 10.1016/j.biomaterials.2009.09.063
Joly, 2013, Geometry-driven cell organization determines tissue growths in scaffold pores: consequences for fibronectin organization, PLoS ONE, 8, e73545, 10.1371/journal.pone.0073545
Yucel, 2009, Vortex-induced injectable silk fibroin hydrogels, Biophys. J., 97, 2044, 10.1016/j.bpj.2009.07.028
Wang, 2008, Sonication-induced gelation of silk fibroin for cell encapsulation, Biomaterials, 29, 1054, 10.1016/j.biomaterials.2007.11.003
Yucel, 2010, Non-equilibrium silk fibroin adhesives, J. Struct. Biol., 170, 406, 10.1016/j.jsb.2009.12.012
Bhardwaj, 2011, Freeze-gelled silk fibroin protein scaffolds for potential applications in soft tissue engineering, Int. J. Biol. Macromol., 49, 260, 10.1016/j.ijbiomac.2011.04.013
Matsumoto, 2006, Mechanisms of silk fibroin sol−gel transitions, J. Phys. Chem. B, 110, 21630, 10.1021/jp056350v
Lu, 2011, Silk fibroin electrogelation mechanisms, Acta Biomater., 7, 2394, 10.1016/j.actbio.2011.02.032
Samal, 2013, Ultrasound sonication effects on silk fibroin protein, Macromol. Mater. Eng., 298, 1201, 10.1002/mame.201200377
Calabrese, 2012, Silk ionomers for encapsulation and differentiation of human MSCs, Biomaterials, 33, 7375, 10.1016/j.biomaterials.2012.06.043
Fini, 2005, The healing of confined critical size cancellous defects in the presence of silk fibroin hydrogel, Biomaterials, 26, 3527, 10.1016/j.biomaterials.2004.09.040
Zhang, 2011, The use of injectable sonication-induced silk hydrogel for VEGF165 and BMP-2 delivery for elevation of the maxillary sinus floor, Biomaterials, 32, 9415, 10.1016/j.biomaterials.2011.08.047
Pallotta, 2014, Characteristics of platelet gels combined with silk, Biomaterials, 35, 3678, 10.1016/j.biomaterials.2013.12.065
Aghaloo, 2004, Evaluation of platelet-rich plasma in combination with anorganic bovine bone in the rabbit cranium: a pilot study, Int. J. Oral Maxillofac. Implant, 19, 59
Dallari, 2007, Enhanced tibial osteotomy healing with use of bone grafts supplemented with platelet gel or platelet gel and bone marrow stromal cells, J. Bone Joint Surg., 89, 2413, 10.2106/00004623-200711000-00011
Kanthan, 2011, Platelet-rich plasma (PRP) enhances bone healing in non-united critical-sized defects: a preliminary study involving rabbit models, Injury, 42, 782, 10.1016/j.injury.2011.01.015
Kasten, 2008, The effect of platelet-rich plasma on healing in critical-size long-bone defects, Biomaterials, 29, 3983, 10.1016/j.biomaterials.2008.06.014
Tamada, 2005, New process to form a silk fibroin porous 3-D structure, Biomacromolecules, 6, 3100, 10.1021/bm050431f
Nazarov, 2004, Porous 3-D scaffolds from regenerated silk fibroin, Biomacromolecules, 5, 718, 10.1021/bm034327e
Wang, 2008, In vivo degradation of three-dimensional silk fibroin scaffolds, Biomaterials, 29, 3415, 10.1016/j.biomaterials.2008.05.002
Correia, 2012, Development of silk-based scaffolds for tissue engineering of bone from human adipose-derived stem cells, Acta Biomater., 8, 2483, 10.1016/j.actbio.2012.03.019
Oliveira, 2012, Aligned silk-based 3-D architectures for contact guidance in tissue engineering, Acta Biomater., 8, 1530, 10.1016/j.actbio.2011.12.015
Kim, 2005, Influence of macroporous protein scaffolds on bone tissue engineering from bone marrow stem cells, Biomaterials, 26, 4442, 10.1016/j.biomaterials.2004.11.013
Uebersax, 2013, Biocompatibility and osteoconduction of macroporous silk fibroin implants in cortical defects in sheep, Eur. J. Pharm. Biopharm., 85, 107, 10.1016/j.ejpb.2013.05.008
Kim, 2005, Three-dimensional aqueous-derived biomaterial scaffolds from silk fibroin, Biomaterials, 26, 2775, 10.1016/j.biomaterials.2004.07.044
Sengupta, 2010, Hypoxia and amino acid supplementation synergistically promote the osteogenesis of human mesenchymal stem cells on silk protein scaffolds, Tissue Eng. Part A, 16, 3623, 10.1089/ten.tea.2010.0302
Hofmann, 2013, Remodeling of tissue-engineered bone structures in vivo, Eur. J. Pharm. Biopharm., 85, 119, 10.1016/j.ejpb.2013.02.011
Thimm, 2011, Initial cell pre-cultivation can maximize ECM mineralization by human mesenchymal stem cells on silk fibroin scaffolds, Acta Biomater., 7, 2218, 10.1016/j.actbio.2011.02.004
Takeuchi, 2003, Deposition of bone-like apatite on silk fiber in a solution that mimics extracellular fluid, J. Biomed. Mater. Res. A, 65, 283, 10.1002/jbm.a.10456
Lin, 2008, Deposition behavior and properties of silk fibroin scaffolds soaked in simulated body fluid, Mater. Chem. Phys., 111, 92, 10.1016/j.matchemphys.2008.03.019
Vetsch, 2015, Effect of fetal bovine serum on mineralization in silk fibroin scaffolds, Acta Biomater., 13, 277, 10.1016/j.actbio.2014.11.025
Marelli, 2012, Silk fibroin derived polypeptide-induced biomineralization of collagen, Biomaterials, 33, 102, 10.1016/j.biomaterials.2011.09.039
Jung, 2015, Silk proteins stimulate osteoblast differentiation by suppressing the Notch signaling pathway in mesenchymal stem cells, Nutr. Res., 33, 162, 10.1016/j.nutres.2012.11.006
Nagano, 2011, Regeneration of the femoral epicondyle on calcium-binding silk scaffolds developed using transgenic silk fibroin produced by transgenic silkworm, Acta Biomater., 7, 1192, 10.1016/j.actbio.2010.10.032
Hunter, 1994, Modulation of crystal formation by bone phosphoproteins: role of glutamic acid-rich sequences in the nucleation of hydroxyapatite by bone sialoprotein, Biochem. J., 302, 175, 10.1042/bj3020175
Harris, 2000, Functional analysis of bone sialoprotein: identification of the hydroxyapatite-nucleating and cell-binding domains by recombinant peptide expression and site-directed mutagenesis, Bone, 27, 795, 10.1016/S8756-3282(00)00392-6
Jin, 2002, Electrospinning Bombyx mori silk with poly(ethylene oxide), Biomacromolecules, 3, 1233, 10.1021/bm025581u
Min, 2004, Electrospinning of silk fibroin nanofibers and its effect on the adhesion and spreading of normal human keratinocytes and fibroblasts in vitro, Biomaterials, 25, 1289, 10.1016/j.biomaterials.2003.08.045
Jin, 2004, Human bone marrow stromal cell responses on electrospun silk fibroin mats, Biomaterials, 25, 1039, 10.1016/S0142-9612(03)00609-4
Ki, 2008, Development of 3-D nanofibrous fibroin scaffold with high porosity by electrospinning: implications for bone regeneration, Biotechnol. Lett., 30, 405, 10.1007/s10529-007-9581-5
Park, 2010, Electrospun silk fibroin scaffolds with macropores for bone regeneration: an in vitro and in vivo study, Tissue Eng. Part A, 16, 1271, 10.1089/ten.tea.2009.0328
Ghosh, 2008, Direct-write assembly of microperiodic silk fibroin scaffolds for tissue engineering applications, Adv. Funct. Mater., 18, 1883, 10.1002/adfm.200800040
Dababneh, 2014, Bioprinting technology: a current state-of-the-art review, J. Manuf. Sci. Eng., 136, 61016, 10.1115/1.4028512
Suntivich, 2014, Inkjet printing of silk nest arrays for cell hosting, Biomacromolecules, 15, 1428, 10.1021/bm500027c
Das, 2015, Bioprintable, cell-laden silk fibroin–gelatin hydrogel supporting multilineage differentiation of stem cells for fabrication of three-dimensional tissue constructs, Acta Biomater., 11, 233, 10.1016/j.actbio.2014.09.023
Schacht, 2015, Biofabrication of cell-loaded 3D spider silk constructs, Angew. Chem. Int. Ed., 54, 2816, 10.1002/anie.201409846
He, 2013, Enhanced osteoinductivity and osteoconductivity through hydroxyapatite coating of silk-based tissue-engineered ligament scaffold, J. Biomed. Mater. Res. A, 101, 555, 10.1002/jbm.a.34333
Panda, 2014, Enhanced osteogenic potential of human mesenchymal stem cells on electrospun nanofibrous scaffolds prepared from eri-tasar silk fibroin, J. Biomed. Mater. Res. B Appl. Biomater., 00B, 1
Zhang, 2010, The osteogenic properties of CaP/silk composite scaffolds, Biomaterials, 31, 2848, 10.1016/j.biomaterials.2009.12.049
J.S.J. Kim, S. Park, W. Kang, H.K.H.K.J. Jang, Signaling responses of osteoblast cells to hydroxyapatite: the activation of ERK and SOX9 2008, 10:138–42, doi: 10.1007/s00774-007-0804-6.
Liu, 2015, Composite scaffolds of nano-hydroxyapatite and silk fibroin enhance mesenchymal stem cell-based bone regeneration via the interleukin 1 alpha autocrine/paracrine signaling loop, Biomaterials, 49, 103, 10.1016/j.biomaterials.2015.01.017
Jiang, 2013, Hydroxyapatite/regenerated silk fibroin scaffold-enhanced osteoinductivity and osteoconductivity of bone marrow-derived mesenchymal stromal cells, Biotechnol. Lett., 35, 657, 10.1007/s10529-012-1121-2
Bhumiratana, 2011, Nucleation and growth of mineralized bone matrix on silk-hydroxyapatite composite scaffolds, Biomaterials, 32, 2812, 10.1016/j.biomaterials.2010.12.058
Ribeiro, 2015, Development of silk fibroin/nanohydroxyapatite composite hydrogels for bone tissue engineering, Eur. Polym. J., 67, 66, 10.1016/j.eurpolymj.2015.03.056
Panda, 2014, Directing osteogenesis of stem cells with hydroxyapatite precipitated electrospun eri-tasar silk fibroin nanofibrous scaffold, J. Biomater. Sci. Ed., 25, 1440, 10.1080/09205063.2014.943548
Suganya, 2014, Aloe vera/silk fibroin/hydroxyapatite incorporated electrospun nanofibrous scaffold for enhanced osteogenesis, J. Biomater. Tissue Eng., 4, 9, 10.1166/jbt.2014.1139
Pascu, 2013, Electrospun composites of PHBV, silk fibroin and nano-hydroxyapatite for bone tissue engineering, Mater. Sci. Eng. C Mater. Biol. Appl., 33, 4905, 10.1016/j.msec.2013.08.012
Kim, 2014, Mechanically-reinforced electrospun composite silk fibroin nanofibers containing hydroxyapatite nanoparticles, Mater. Sci. Eng. C Mater. Biol. Appl., 40, 324, 10.1016/j.msec.2014.04.012
Li, 2006, Electrospun silk-BMP-2 scaffolds for bone tissue engineering, Biomaterials, 27, 3115, 10.1016/j.biomaterials.2006.01.022
Chen, 2012, Preparation and characterization of biomimetic silk fibroin/chitosan composite nanofibers by electrospinning for osteoblasts culture, Nanoscale Res. Lett., 7, 1, 10.1186/1556-276X-7-170
Ding, 2015, Delivery of demineralized bone matrix powder using a salt-leached silk fibroin carrier for bone regeneration, J. Mater. Chem. B, 3, 3177, 10.1039/C5TB00046G
Rajkhowa, 2010, Reinforcing silk scaffolds with silk particles, Macromol. Biosci., 10, 599, 10.1002/mabi.200900358
Gil, 2011, Mechanical improvements to reinforced porous silk scaffolds, J. Biomed. Mater. Res. A, 99, 16, 10.1002/jbm.a.33158
Mandal, 2012, High-strength silk protein scaffolds for bone repair, Proc. Natl. Acad. Sci. U.S.A., 109, 7699, 10.1073/pnas.1119474109
Rockwood, 2011, Ingrowth of human mesenchymal stem cells into porous silk particle reinforced silk composite scaffolds: an in vitro study, Acta Biomater., 7, 144, 10.1016/j.actbio.2010.07.020
Jones, 2009, Osteoblast: osteoclast co-cultures on silk fibroin, chitosan and PLLA films, Biomaterials, 30, 5376, 10.1016/j.biomaterials.2009.07.028
Mizuno, 2000, Type I collagen-induced osteoblastic differentiation of bone-marrow cells mediated by collagen-α2β1 integrin interaction, J. Cell. Physiol., 184, 207, 10.1002/1097-4652(200008)184:2<207::AID-JCP8>3.0.CO;2-U
Kim, 2014, Comparable efficacy of silk fibroin with the collagen membranes for guided bone regeneration in rat calvarial defects, J. Adv. Prosthodont., 6, 539, 10.4047/jap.2014.6.6.539
Kim, 2005, Biological efficacy of silk fibroin nanofiber membranes for guided bone regeneration, J. Biotechnol., 120, 327, 10.1016/j.jbiotec.2005.06.033
Perrone, 2014, The use of silk-based devices for fracture fixation, Nat. Commun., 5, 3385, 10.1038/ncomms4385
Meinel, 2006, Silk based biomaterials to heal critical sized femur defects, Bone, 39, 922, 10.1016/j.bone.2006.04.019
Jiang, 2009, Mandibular repair in rats with premineralized silk scaffolds and BMP-2-modified bMSCs, Biomaterials, 30, 4522, 10.1016/j.biomaterials.2009.05.021
Zhao, 2009, Apatite-coated silk fibroin scaffolds to healing mandibular border defects in canines, Bone, 45, 517, 10.1016/j.bone.2009.05.026
Wang, 2014, Bone Morphogenetic Protein (BMP) signaling in development and human diseases, Genes Dis., 1, 87, 10.1016/j.gendis.2014.07.005
Karageorgiou, 2006, Porous silk fibroin 3-D scaffolds for delivery of bone morphogenetic protein-2 in vitro and in vivo, J. Biomed. Mater. Res., Part A, 78A, 324, 10.1002/jbm.a.30728
Han, 2015, Epigenetically modified bone marrow stromal cells (BMSCs) in silk scaffolds promote craniofacial bone repair and wound healing, Tissue Eng. Part A, 10.1089/ten.tea.2014.0484
Ye, 2011, Critical-size calvarial bone defects healing in a mouse model with silk scaffolds and SATB2-modified iPSCs, Biomaterials, 32, 5065, 10.1016/j.biomaterials.2011.03.053
Wu, 2011, A comparative study of mesoporous glass/silk and non-mesoporous glass/silk scaffolds: physiochemistry and in vivo osteogenesis, Acta Biomater., 7, 2229, 10.1016/j.actbio.2010.12.019
Midha, 2013, Preconditioned 70S30C bioactive glass foams promote osteogenesis in vivo, Acta Biomater., 9, 9169, 10.1016/j.actbio.2013.07.014
Meinel, 2005, Silk implants for the healing of critical size bone defects, Bone, 37, 688, 10.1016/j.bone.2005.06.010
Xynos, 2001, Gene-expression profiling of human osteoblasts following treatment with the ionic products of Bioglass® 45S5 dissolution, J. Biomed. Mater. Res., 55, 151, 10.1002/1097-4636(200105)55:2<151::AID-JBM1001>3.0.CO;2-D
Kim, 2008, Bone tissue engineering with premineralized silk scaffolds, Bone, 42, 1226, 10.1016/j.bone.2008.02.007
Kim, 2013, A novel in vivo platform for studying alveolar bone regeneration in rat, J. Tissue Eng., 4
N. Sahu, P. Baligar, S. Midha, B. Kundu, M. Bhattacharjee, S. Mukherjee et al., Nonmulberry silk fibroin scaffold shows superior osteoconductivity than mulberry silk fibroin in calvarial bone regeneration. Adv. Healthc. Mater. n.d., accepted.
Silva, 2013, Silk hydrogels from non-mulberry and mulberry silkworm cocoons processed with ionic liquids, Acta Biomater., 9, 8972, 10.1016/j.actbio.2013.06.044
Kanczler, 2008, Osteogenesis and angiogenesis: the potential for engineering bone, Eur. Cell Mater., 15, 100, 10.22203/eCM.v015a08
Sun, 2012, Direct-write assembly of 3D silk/hydroxyapatite scaffolds for bone co-cultures, Adv. Healthc. Mater., 1, 729, 10.1002/adhm.201200057
Unger, 2010, The rapid anastomosis between prevascularized networks on silk fibroin scaffolds generated in vitro with cocultures of human microvascular endothelial and osteoblast cells and the host vasculature, Biomaterials, 31, 6959, 10.1016/j.biomaterials.2010.05.057
Bhattacharjee, 2013, The role of 3D structure and protein conformation on the innate and adaptive immune responses to silk-based biomaterials, Biomaterials, 34, 8161, 10.1016/j.biomaterials.2013.07.018
Uebersax, 2008, Insulin-like growth factor I releasing silk fibroin scaffolds induce chondrogenic differentiation of human mesenchymal stem cells, J. Control. Release, 127, 12, 10.1016/j.jconrel.2007.11.006
Wang, 2009, Growth factor gradients via microsphere delivery in biopolymer scaffolds for osteochondral tissue engineering, J. Control. Release, 134, 81, 10.1016/j.jconrel.2008.10.021
Wang, 2008, Controlled release from multilayer silk biomaterial coatings to modulate vascular cell responses, Biomaterials, 29, 894, 10.1016/j.biomaterials.2007.10.055
Uebersax, 2007, Silk fibroin matrices for the controlled release of nerve growth factor (NGF), Biomaterials, 28, 4449, 10.1016/j.biomaterials.2007.06.034
Schneider, 2009, Biofunctionalized electrospun silk mats as a topical bioactive dressing for accelerated wound healing, Acta Biomater., 5, 2570, 10.1016/j.actbio.2008.12.013
Farokhi, 2014, Bio-hybrid silk fibroin/calcium phosphate/PLGA nanocomposite scaffold to control the delivery of vascular endothelial growth factor, Mater. Sci. Eng., C, 35, 401, 10.1016/j.msec.2013.11.023
Karageorgiou, 2004, Bone morphogenetic protein-2 decorated silk fibroin films induce osteogenic differentiation of human bone marrow stromal cells, J. Biomed. Mater. Res. A, 71, 528, 10.1002/jbm.a.30186
Shi, 2013, Silk fibroin-based complex particles with bioactive encrustation for bone morphogenetic protein 2 delivery, Biomacromolecules, 14, 4465, 10.1021/bm401381s
Zhang, 2005, Synthesis, characterization and immunogenicity of silk fibroin-l-asparaginase bioconjugates, J. Biotechnol., 120, 315, 10.1016/j.jbiotec.2005.06.027
Haider, 2005, Molecular engineering of silk-elastin like polymers for matrix-mediated gene delivery: biosynthesis and characterization, Mol. Pharm., 2, 139, 10.1021/mp049906s
Chen, 2007, Homogeneous osteogenesis and bone regeneration by demineralized bone matrix loading with collagen-targeting bone morphogenetic protein-2, Biomaterials, 28, 1027, 10.1016/j.biomaterials.2006.10.013
Kolambkar, 2011, An alginate-based hybrid system for growth factor delivery in the functional repair of large bone defects, Biomaterials, 32, 65, 10.1016/j.biomaterials.2010.08.074
Diab, 2012, A silk hydrogel-based delivery system of bone morphogenetic protein for the treatment of large bone defects, J. Mech. Behav. Biomed. Mater., 11, 123, 10.1016/j.jmbbm.2011.11.007