Significance of Transporter Associated with Antigen Processing 2 (TAP2) Gene Polymorphisms in Susceptibility to Dengue Viral Infection

Gubler DJ. Dengue and dengue hemorrhagic fever. Clin Microbiol Rev 1998;11:480–93.

Mongkolsapaya J, Duangchinda T, Dejnirattisai W, Vasanawathana S, Avirutnan P. T cell responses in dengue hemorrhagic fever: are cross-reactive T cells suboptimal. J Immunol 2006;176:3821–9.

Rammensee FM, Falk K, Rotzschke O. Peptides naturally resented by MHC class I molecules. Annu Rev Immunol 1993;11:213–44.

Kelly A, Powis SH, Kerr LA, Mockridge I, Elliot T, Bastin J, Uchanska-Ziegler B, Ziegler A, Trowsdale J, Townsend A. Assembly and function of the two ABC transporter proteins encoded in the human major histocompatibility complex. Nature 1992;355:641–644.

Powis SJ, Townsend A, Deverson EV, Bastin J, Butcher GW, Howard JC. Restoration of antigen presentation to the mutant cell line RMA-S by an MHC-linked transporter. Nature 1991;354:528–31.

Van Kaer L, Ashton-Rickardt PG, Ploegh HL, Tonegawa S. TAP1 mutant mice are deficient in antigen presentation, surface class I molecules, and CD4281 T cells. Cell 1992;71:1205–14.

Spies T, Cerundolo V, Colonna P, Cresswell P, Townsend A, DeMars R. Presentation of viral antigen by MHC class I molecules is dependent on a putative peptide transporter heterodimer. Nature 1992;355:644–6.

Bahram S, Arnold D, Bresnahan M, Strominger JL, Spies T. Two putative subunits of a peptide pump encoded in the human major histocompatibility complex class II region. Proc Natl Acad Sci U S A 1991;88:10094–8.

Colonna M, Bresnahan M, Bahram S, Strominger JL, Spies T. Allelic variants of the human putative peptide transporter involved in antigen processing. Proc Natl Acad Sci U S A 1992;89:3932–6.

Spies T, De Mars R. Restored expression of major histocompatibility class I molecules by gene transfer of a putative peptide transporter. Nature 1991;351:323–4.

Powis SJ, Deverson EV, Coadwell WJ, Ciruela A, Huskisson NS, Smith H, Butcher GW, Howard JC. Effect of polymorphism of an MHC-linked transporter on the peptides assembled in a class I molecule. Nature 1992;357:211–215.

Powis SJ, Young LL, Joly E, Barker PJ, Richardson L, Brandt RP, Melief CJ, Howard JC, Butcher GW. The rat cim effect: TAP allele-dependent changes in a class I MHC anchor motif and evidence against C-terminal trimming of peptides in the ER. Immunity 1996;4:159–165.

Momburg F, Armandola EA, Post M, H, mmerling GJ. Residues in TAP2 peptide transporters controlling substrate specificity. J Immunol 1996;156:1756–1763.

Momburg F, Mullbacher A, Lobigs M. Modulation of transporter associated with antigen processing (TAP)-mediated peptide import into the endoplasmic reticulum by flavivirus infection. J Virol 2001;75:5663–71.

Stephens HA, Klaythong R, Sirikong M, Vaughn DW, Green S, Kalayanarooj S, et al. HLA-A and -B allele associations with secondary dengue virus infections correlate with disease severity and the infecting viral serotype in ethnic Thais. Tissue Antigens 2002;60:309–18.

Chaturvedi U, Nagar R, Shrivastava R. Dengue and dengue haemorrhagic fever: implications of host genetics. FEMS Immunol Med Microbiol. 2006;47:155–66.

LaFleur C, Granados J, Vargas-Alarcon G, Ruiz-Morales J, Villarreal-Garza C, Higuera L, et al. HLA-DR antigen frequencies in Mexican patients with dengue virus infection: HLA-DR4 as a possible genetic resistance factor for dengue hemorrhagic fever. Hum Immunol 2002;63:1039–44.

Chiewsilp P, Scott RM, Bhamarapravati N. Histocompatibility antigens and dengue hemorrhagic fever. Am J Trop Med Hyg 1981;30:1100–5.

Loke H, Bethell D, Phuong CX, Day N, White N, Farrar J, et al. Susceptibility to dengue hemorrhagic fever in vietnam: evidence of an association with variation in the vitamin D receptor and Fc gamma receptor IIa genes. Am J Trop Med Hyg 2002;67:102–6.

Sakuntabhai A, Turbpaiboon C, Casademont I, Chuansumrit A, Lowhnoo T, Kajaste-Rudnitski A, et al. A variant in the CD209 promoter is associated with severity of dengue disease. Nat Genet 2005;37:507–13.

Sierra Bde L, Kouri G, Guzman MG. Race: a risk factor for dengue hemorrhagic fever. Arch Virol 2007;152:533–42.

Wang WK, Chen HL, Yang CF, Hsieh SC, Juan CC. Slower Rates of Clearance of Viral Load and Virus-Containing Immune Complexes in Patients with Dengue Hemorrhagic Fever. Clin Infect Dis 2006;43:1023–30.

Soundravally R, Hoti SL. Immunopathogenesis of dengue hemorrhagic fever and shock syndrome: role of TAP and HPA gene polymorphism. Hum Immunol (2007). DOI 10.1016/j.humimm.2007.09.007 , http://dx.doi.org/10.1016/j.humpath.2007.01.028 (in press).

Hoti SL, Soundravally R, Rajendran G, Das LK, Ravi R, Das PK. Dengue and dengue haemorrhagic fever outbreaks in Pondicherry, South India, during 2003–2004: emergence of DENV-3. Dengue Bull 2006;30:42–50.

World Health Organization. Dengue Haemorrhagic Fever: Diagnosis, Treatment, Prevention, and Control. 2nd ed. Geneva: World Health Organization; 1997.

Harris E, Roberts TG, Smith L, Selle J, Kramer LD, Valle S, et al. Typing of dengue viruses in clinical specimens and mosquitoes by single-tube multiplex reverse transcriptase-PCR. J Clin Microbiol 1998;36:2634–9.

Powis SH, Tonks S, Mockridge I, Kelly AP, Bodmer JG, Trowsdale J. Alleles and haplotypes of the MHC-encoded ABC transporters TAP1 and TAP2. Immunogenetics 1993;37:373–80.

McGuire W, Hill AVS, Allsopp CEM, Greenwood BM, Kwjatkowski D. Variation in the TNF-a promoter region associated with susceptibility to cerebral malaria. Nature 1994;371:508–511.

Kaslow RA, Carrington M, Apple R, Park L, Munoz A, Saah AJ, Goedert JJ, Winkler C, O’ Brien SJ, Rinaldo C, Detels R, Blattner W, Phair J, Erlich H, Mann DL. Influence of combinations of human major histocompatibility complex genes on the courses of HIV-1 infection. Nat Med 1996;2:405–411.

Hohler T, Gerken G, Schneider PM, Meyer zum B, shenfelde KH, Rittner C. Antigen-processing polymorphisms in chronic hepatitis C infection. Exp Clin Immunogenet 1996;13:7–11.

Rothman AL, Ennis FA. Immunopathogenisis of dengue hemorrhagic fever. Virology 1999;257:1–6.

Sangkawibha N, Rojanasuphot S, Ahandrik S, Viriyapongse S, Jatanasen S, Salitul V, Phanthumachinda B, Halstead SB. Risk factors in dengue shock syndrome: a prospective epidemiologic study in Rayong, Thailand. I. The 1980 outbreak. Am J Epidemiol 1984;120:653–669.

Halstead SB. Pathogenesis of dengue. Challenges to molecular biology. Science 1988;239:476–481.

Kurane I, Takasaki T. Dengue fever and dengue haemorrhagic fever: challenges of controlling an enemy still at large. Rev Med Virol 2001;11:301–311.

Chatuverdi UC, Agarwal R, Elbishbishi EA, Mustafa AS. Cytokine cascade in dengue hemorrhagic fever: implications for pathogenesis. FEMS Immunol Med Microbiol 2000;28:183–188.

Mongkolsapaya J, Dejnirattisai W, Xu X, Vasanawathana S, Tangthawornchaikul N, Chairunsri A, Sawasdivorn S, Duangchinda T, Dong T, Rowlang-Jones S, Yenchitsomanus P, McMichel A, Malasit P, Screaton G. Original antigenic sin and apoptosis in the pathogenesis of dengue hemorrhagic fever. Nat Med 2003;9:921–927.

Hedrick PW. Evolution at HLA: possible explanations for the deficiency of homozygotes in two populations. Hum Hered 1990;40:213–220.

Safa AR, Stern RK, Choi K, et al. Molecular basis of preferential resistance to colchicine in multidrug-resistant human cells conferred by Gly-185+ Val-185 substitution in P-glycoprotein. Proc Natl Acad Sci U S A 1990;87:7225–7229.

Pinheiro FP, Corber SJ. Global situation of dengue and dengue hemorrhagic fever and its emergence in the Americas. World Health Stat 1997;50:161–9.

Kabra SK, Jain Y, Pandey RM, Madhulika T, Singhal P, Tripathi S, Broor PS, Seth V. Dengue haemorrhagic fever in children in the 1996 Delhi epidemic. Trans R Soc Trop Med Hyg 1999;93:294–8.