Signalling, cell cycle and pluripotency in embryonic stem cells
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Gardner, 1997, Reflections on the biology of embryonic stem cells, Int. J. Dev. Biol., 41, 235
Nichols, 2001, Introducing embryonic stem cells, Curr. Biol., 11, R503, 10.1016/S0960-9822(01)00304-9
Smith, 2001, Embryonic stem cells, 205
Beddington, 1989, An assessment of the developmental potential of embryonic stem cells in the midgestation mouse embryo, Development, 105, 733, 10.1242/dev.105.4.733
Doetschman, 1985, The in vitro development of blastocyst-derived embryonic stem cell lines: formation of visceral yolk sac, blood islands and myocardium, J. Embryol. Exp. Morphol., 87, 27
Keller, 1995, In vitro differentiation of embryonic stem cells, Curr. Opin. Cell Biol., 7, 862, 10.1016/0955-0674(95)80071-9
Thomson, 1998, Embryonic stem cell lines derived from human blastocysts, Science, 282, 1145, 10.1126/science.282.5391.1145
Savatier, 1994, Contrasting patterns of retinoblastoma protein expression in mouse embryonic stem cells and embryonic fibroblasts, Oncogene, 9, 809
Savatier, 1996, Withdrawal of differentiation inhibitory activity/leukemia inhibitory factor up-regulates D-type cyclins and cyclin-dependent kinase inhibitors in mouse embryonic stem cells, Oncogene, 12, 309
Smith, 2001, Embryo-derived stem cells: of mice and men, Annu. Rev. Cell Dev. Biol., 17, 435, 10.1146/annurev.cellbio.17.1.435
Suda, 1987, Mouse embryonic stem cells exhibit indefinite proliferative potential, J. Cell Physiol., 133, 197, 10.1002/jcp.1041330127
Smith, 1988, Inhibition of pluripotential embryonic stem cell differentiation by purified polypeptides, Nature, 336, 688, 10.1038/336688a0
Williams, 1988, Myeloid leukaemia inhibitory factor maintains the developmental potential of embryonic stem cells, Nature, 336, 684, 10.1038/336684a0
Yoshida, 1994, Maintenance of the pluripotential phenotype of embryonic stem cells through direct activation of gp130 signalling pathways, Mech. Dev., 45, 163, 10.1016/0925-4773(94)90030-2
Rathjen, 1990, Differentiation inhibiting activity is produced in matrix-associated and diffusible forms that are generated by alternate promoter usage, Cell, 62, 1105, 10.1016/0092-8674(90)90387-T
Stewart, 1992, Blastocyst implantation depends on maternal expression of leukaemia inhibitory factor, Nature, 359, 76, 10.1038/359076a0
Davis, 1993, LIFRβ and gp130 as heterodimerizing signal transducers of the tripartite CNTF receptor, Science, 260, 1805, 10.1126/science.8390097
Niwa, 1998, Self-renewal of pluripotent embryonic stem cells is mediated via activation of STAT3, Genes Dev., 12, 2048, 10.1101/gad.12.13.2048
Ernst, 1999, The carboxyl-terminal domains of gp130-related cytokine receptors are necessary for suppressing embryonic stem cell differentiation. Involvement of STAT3, J. Biol. Chem., 274, 9729, 10.1074/jbc.274.14.9729
Boeuf, 1997, Leukemia inhibitory factor-dependent transcriptional activation in embryonic stem cells, J. Cell Biol., 138, 1207, 10.1083/jcb.138.6.1207
Matsuda, 1999, STAT3 activation is sufficient to maintain an undifferentiated state of mouse embryonic stem cells, EMBO J., 18, 4261, 10.1093/emboj/18.15.4261
Kolch, 2000, Meaningful relationships: the regulation of the Ras/Raf/MEK/ERK pathway by protein interactions, Biochem. J., 351, 289, 10.1042/0264-6021:3510289
Hibi, 2000, Gab-family adapter molecules in signal transduction of cytokine and growth factor receptors, and T and B cell antigen receptors, Leuk. Lymphoma, 37, 299, 10.3109/10428190009089430
Burdon, 1999, Suppression of SHP-2 and ERK signalling promotes self-renewal of mouse embryonic stem cells, Dev. Biol., 210, 30, 10.1006/dbio.1999.9265
Schmitz, 2000, SOCS3 exerts its inhibitory function on interleukin-6 signal transduction through the SHP2 recruitment site of gp130, J. Biol. Chem., 275, 12848, 10.1074/jbc.275.17.12848
Cheng, 1998, Mammalian Grb2 regulates multiple steps in embryonic development and malignant transformation, Cell, 95, 793, 10.1016/S0092-8674(00)81702-X
Qu, 1998, Shp-2 has a positive regulatory role in ES cell differentiation and proliferation, Oncogene, 17, 433, 10.1038/sj.onc.1201920
Burdon, 1999, Signalling mechanisms regulating self-renewal and differentiation of pluripotent embryonic stem cells, Cells Tissues Organs, 165, 131, 10.1159/000016693
Vanhaesebroeck, 2000, The PI3K–PDK1 connection: more than just a road to PKB, Biochem. J., 346, 561, 10.1042/0264-6021:3460561
Sun, 1999, PTEN modulates cell cycle progression and cell survival by regulating phosphatidylinositol 3,4,5,-trisphosphate and Akt/protein kinase B signaling pathway, Proc. Natl Acad. Sci. U. S. A., 96, 6199, 10.1073/pnas.96.11.6199
Williams, 2000, The role of 3-phosphoinositide-dependent protein kinase 1 in activating AGC kinases defined in embryonic stem cells, Curr. Biol., 10, 439, 10.1016/S0960-9822(00)00441-3
Kobayashi, 1999, Activation of serum- and glucocorticoid-regulated protein kinase by agonists that activate phosphatidylinositide 3-kinase is mediated by 3-phosphoinositide-dependent protein kinase-1 (PDK1) and PDK2, Biochem. J., 339, 319, 10.1042/0264-6021:3390319
Park, 1999, Serum and glucocorticoid-inducible kinase (SGK) is a target of the PI3-kinase-stimulated signaling pathway, EMBO J., 18, 3024, 10.1093/emboj/18.11.3024
Tu, 2001, Embryonic and hematopoietic stem cells express a novel SH2-containing inositol 5’-phosphatase isoform that partners with the Grb2 adapter protein, Blood, 98, 2028, 10.1182/blood.V98.7.2028
Harbour, 2000, The Rb/E2F pathway: expanding roles and emerging paradigms, Genes Dev., 14, 2393, 10.1101/gad.813200
Harbour, 1999, Cdk phosphorylation triggers sequential intramolecular interactions that progressively block Rb functions as cells move through G1, Cell, 98, 859, 10.1016/S0092-8674(00)81519-6
Bartek, 2001, Pathways governing G1/S transition and their response to DNA damage, FEBS Lett., 490, 117, 10.1016/S0014-5793(01)02114-7
Bartkova, 1997, Aberrations of the G1- and G1/S-regulating genes in human cancer, Prog. Cell Cycle Res., 3, 211, 10.1007/978-1-4615-5371-7_16
Sherr, 1999, CDK inhibitors: positive and negative regulators of G1-phase progression, Genes Dev., 13, 1501, 10.1101/gad.13.12.1501
Robanus-Maandag, 1998, p107 is a suppressor of retinoblastoma development in pRb-deficient mice, Genes Dev., 12, 1599, 10.1101/gad.12.11.1599
LeCouter, 1996, Cloning and expression of the Rb-related mouse p130 mRNA, Oncogene, 12, 1433
Lukas, 1995, Retinoblastoma-protein-dependent cell-cycle inhibition by the tumour suppressor p16, Nature, 375, 503, 10.1038/375503a0
Medema, 1995, Growth suppression by p16ink4 requires functional retinoblastoma protein, Proc. Natl Acad. Sci. U. S. A., 92, 6289, 10.1073/pnas.92.14.6289
Dannenberg, 2000, Ablation of the retinoblastoma gene family deregulates G(1) control causing immortalization and increased cell turnover under growth-restricting conditions, Genes Dev., 14, 3051, 10.1101/gad.847700
Sage, 2000, Targeted disruption of the three Rb-related genes leads to loss of G(1) control and immortalization, Genes Dev., 14, 3037, 10.1101/gad.843200
St Croix, 1998, E-Cadherin-dependent growth suppression is mediated by the cyclin-dependent kinase inhibitor p27(KIP1), J. Cell Biol., 142, 557, 10.1083/jcb.142.2.557
Brown, 1997, Bypass of senescence after disruption of p21CIP1/WAF1 gene in normal diploid human fibroblasts, Science, 277, 831, 10.1126/science.277.5327.831
Aladjem, 1998, ES cells do not activate p53-dependent stress responses and undergo p53-independent apoptosis in response to DNA damage, Curr. Biol., 8, 145, 10.1016/S0960-9822(98)70061-2
Prost, 1998, p53-independent DNA repair and cell cycle arrest in embryonic stem cells, FEBS Lett., 425, 499, 10.1016/S0014-5793(98)00296-8
Hall, 1996, Genetic alterations of cyclins, cyclin-dependent kinases, and Cdk inhibitors in human cancer, Adv. Cancer Res., 68, 67, 10.1016/S0065-230X(08)60352-8
Wianny, 1998, G1-phase regulators, cyclin D1, cyclin D2, and cyclin D3: up-regulation at gastrulation and dynamic expression during neurulation, Dev. Dyn., 212, 49, 10.1002/(SICI)1097-0177(199805)212:1<49::AID-AJA5>3.0.CO;2-2
Lavoie, 1996, Cyclin D1 expression is regulated positively by the p42/p44MAPK and negatively by the p38/HOGMAPK pathway, J. Biol. Chem., 271, 20608, 10.1074/jbc.271.34.20608
Albanese, 1995, Transforming p21ras mutants and c-Ets-2 activate the cyclin D1 promoter through distinguishable regions, J. Biol. Chem., 270, 23589, 10.1074/jbc.270.40.23589
Winston, 1996, Regulation of the cell cycle machinery by oncogenic ras, Oncogene, 12, 127
Jirmanova, L. et al. (2002) Differential contributions of ERK and PI3-kinase to the regulation of cyclin D1 expression and to the control of the G1/S transition in mouse embryonic stem cells. Oncogene (in press)
Diehl, 1998, Glycogen synthase kinase-3β regulates cyclin D1 proteolysis and subcellular localization, Genes Dev., 12, 3499, 10.1101/gad.12.22.3499
Fang, 1996, Dependence of cyclin E-CDK2 kinase activity on cell anchorage, Science, 271, 499, 10.1126/science.271.5248.499
Fukada, 1998, STAT3 orchestrates contradictory signals in cytokine-induced G1 to S cell-cycle transition, EMBO J., 17, 6670, 10.1093/emboj/17.22.6670
Shirogane, 1999, Synergistic roles for Pim-1 and c-Myc in STAT3-mediated cell cycle progression and antiapoptosis, Immunity, 11, 709, 10.1016/S1074-7613(00)80145-4
Badache, 2001, Interleukin 6 inhibits proliferation and, in cooperation with an epidermal growth factor receptor autocrine loop, increases migration of T47D breast cancer cells, Cancer Res., 61, 383
Novitch, 1999, pRb is required for MEF2-dependent gene expression as well as cell- cycle arrest during skeletal muscle differentiation, Curr. Biol., 9, 449, 10.1016/S0960-9822(99)80210-3
Gu, 1993, Interaction of myogenic factors and the retinoblastoma protein mediates muscle cell commitment and differentiation, Cell, 72, 309, 10.1016/0092-8674(93)90110-C
Chen, 1996, Retinoblastoma protein directly interacts with and activates the transcription factor NF-IL6, Proc. Natl Acad. Sci. U. S. A., 93, 465, 10.1073/pnas.93.1.465
Chen, 1996, Retinoblastoma protein positively regulates terminal adipocyte differentiation through direct interaction with C/EBPs, Genes Dev., 10, 2794, 10.1101/gad.10.21.2794
Thomson, 1995, Isolation of a primate embryonic stem cell line, Proc. Natl Acad. Sci. U. S. A., 92, 7844, 10.1073/pnas.92.17.7844
Shamblott, 1998, Derivation of pluripotent stem cells from cultured human primordial germ cells, Proc. Natl Acad. Sci. U. S. A., 95, 13726, 10.1073/pnas.95.23.13726