Sialylation shapes mucus architecture inhibiting bacterial invasion in the colon

Mucosal Immunology - Tập 16 - Trang 624-641 - 2023
Mugen Taniguchi1,2, Ryu Okumura1,3,4, Takahisa Matsuzaki5,6, Ayaka Nakatani1,7, Kei Sakaki1, Shota Okamoto1,3, Airi Ishibashi1,3, Haruka Tani1,3, Momoka Horikiri6, Naritaka Kobayashi8, Hiroshi Y. Yoshikawa6, Daisuke Motooka4,9, Daisuke Okuzaki3,9, Shota Nakamura9, Toshiyuki Kida4,10, Akihiko Kameyama11, Kiyoshi Takeda1,3,4,12
1Department of Microbiology and Immunology, Graduate School of Medicine, Osaka University, Osaka, Japan
2Infectious Diseases Unit, Department of Medical Innovations, New Drug Research Division, Otsuka Pharmaceutical Co., Ltd., Tokushima, Japan
3WPI Immunology Frontier Research Center, Osaka University, Osaka, Japan
4Institute for Open and Transdisciplinary Research Initiative, Osaka University, Osaka, Japan
5Center for Future Innovation, Graduate School of Engineering, Osaka University, Osaka, Japan
6Department of Applied Physics, Graduate School of Engineering, Osaka University, Osaka, Japan
7Department of Otorhinolaryngology-Head and Neck Surgery, Graduate School of Medicine, Osaka University, Osaka, Japan
8Department of Electronic Systems Engineering, The University of Shiga Prefecture, Shiga, Japan
9Department of Infection Metagenomics, Genome Information Research Center, Research Institute for Microbial Diseases, Osaka University, Osaka, Japan
10Department of Applied Chemistry, Graduate School of Engineering, Osaka University, Osaka, Japan
11Cellular and Molecular Biotechnology Research Institute, National Institute of Advanced Industrial Science and Technology (AIST), Ibaraki, Japan
12Center for Infectious Disease Education and Research, Osaka University, Osaka, Japan

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