Short communication: Evidence for a major gene by polygene interaction for milk production traits in German Holstein dairy cattle

Journal of Dairy Science - Tập 94 - Trang 1597-1600 - 2011
M. Streit1, N. Neugebauer1, T.H.E. Meuwissen2, J. Bennewitz1
1Institute of Animal Husbandry and Breeding, University of Hohenheim, 70599 Stuttgart, Germany
2Department of Animal and Aquacultural Sciences, Norwegian University of Life Sciences, Ås, Norway

Tài liệu tham khảo

Bennewitz, 2004, The DGAT1 K232A mutation is not solely responsible for the milk production quantitative trait locus on the bovine chromosome 14, J. Dairy Sci., 87, 431, 10.3168/jds.S0022-0302(04)73182-3 Carlborg, 2004, Epistasis: Too often neglected in complex trait studies?, Genetics, 5, 618 Falconer, 1996 Gautier, 2007, Characterization of the DGAT1 K232A and variable number of tandem repeat polymorphisms in French dairy cattle, J. Dairy Sci., 90, 2980, 10.3168/jds.2006-707 Gilmour, 2006 Grisart, 2002, Positional candidate cloning of a QTL in dairy cattle: Identification of a missense mutation in the bovine DGAT1 K232A gene with major effect on milk yield and composition, Genome Res., 12, 222, 10.1101/gr.224202 Grisart, 2004, Genetic and functional confirmation of the causality of the DGAT1 K232A quantitative trait nucleotide in affecting milk yield and confirmation, Proc. Natl. Acad. Sci. USA, 101, 2398, 10.1073/pnas.0308518100 Hill, 2008, Data and theory point to mainly additive genetic variance for complex traits, PLoS Genet., 4, 10.1371/journal.pgen.1000008 Hinrichs, 2010, A two step approach to detect interaction between QTL and a known major gene in dairy cattle Kacser, 1973, The control of flux, Symp. Soc. Exp. Biol., 27, 65 Kacser, 1981, The molecular basis of dominance, Genetics, 97, 639, 10.1093/genetics/97.3-4.639 Seidenspinner, 2009, The need for sharp phenotypes in QTL mapping for calving traits in dairy cattle, J. Anim. Breed. Genet., 126, 455, 10.1111/j.1439-0388.2009.00804.x Self, 1987, Asymptotic properties of maximum likelihood estimators and likelihood ratio tests under nonstandard conditions, J. Am. Stat. Assoc., 82, 605, 10.1080/01621459.1987.10478472 Thaller, 2003, Effects of DGAT1 K232A variants on milk production traits in German cattle breeds, J. Anim. Sci., 81, 1911, 10.2527/2003.8181911x Winter, 2002, Association of a lysine-232/alanine polymorphism in a bovine gene encoding acyl-CoA:diacylglycerol acyltransferase (DGAT1) with variation at a quantitative trait locus for milk fat percentage, Proc. Natl. Acad. Sci. USA, 99, 9300, 10.1073/pnas.142293799