Sex determination: insights from the chicken

BioEssays - Tập 26 Số 2 - Trang 120-132 - 2004
Craig A. Smith1, Andrew Sinclair1
1Murdoch Childrens Research Institute and Department of Paediatrics, Royal Childrens Hospital, Victoria, Australia.

Tóm tắt

AbstractNot all vertebrates share the familiar system of XX:XY sex determination seen in mammals. In the chicken and other birds, sex is determined by a ZZ:ZW sex chromosome system. Gonadal development in the chicken has provided insights into the molecular genetics of vertebrate sex determination and how it has evolved. Such comparative studies show that vertebrate sex‐determining pathways comprise both conserved and divergent elements. The chicken embryo resembles lower vertebrates in that estrogens play a central role in gonadal sex differentiation. However, several genes shown to be critical for mammalian sex determination are also expressed in the chicken, but their expression patterns differ, indicating functional plasticity. While the genetic trigger for sex determination in birds remains unknown, some promising candidate genes have recently emerged. The Z‐linked gene, DMRT1, supports the Z‐dosage model of avian sex determination. Two novel W‐linked genes, ASW and FET1, represent candidate female determinants. BioEssays 26:120–132, 2004. © 2004 Wiley Periodicals, Inc.

Từ khóa


Tài liệu tham khảo

10.1002/bies.950180107

10.1002/bies.950170407

10.1002/bies.950170113

10.1002/jez.1088

10.1038/6769

10.1159/000015567

10.1073/pnas.0636925100

Thorne M, 1993, Sex chromosomes and sex determining genes, 201

10.1071/RD9951185

10.1007/978-3-642-88178-7

10.1002/mrd.1080420403

Dieterlen‐Lievre F, 1986, A time clock for meiosis initiation is programmed in avian germ cells, Prog Dev Biol, 183

10.1111/j.1440-169X.1984.00403.x

10.1007/BF00326588

10.1242/dev.127.12.2741

10.1016/0012-1606(78)90289-0

McCarrey JR, 1982, Functional differentiation of chick gonads following depletion of primordial germ cells, J Embryol Exp Morph, 68, 161

10.1002/bies.950130402

10.1002/0470868732.ch15

10.1159/000143997

Carlon N, 1985, Origin of the somatic components of chick embryonic gonads, Arch Anat Microsc Morphol Exp, 74, 52

10.1111/j.1432-0436.1988.tb00720.x

10.1002/jmor.1050880104

10.1016/S0925-4773(99)00327-5

Tilman K, 1999, Mesonephric cell migration induces testis cord formation and Sertoli cell differentiation in the mammalian gonad, Development, 126, 2883, 10.1242/dev.126.13.2883

Rodemer E, 1986, Gonadal development of the chick embryo following microsurgically caused agenesis of the mesonephros and using interspecific quail‐chick chimeras, J Embryol Exp Morph, 98, 269

10.1006/dbio.2002.0578

Scheib D, 1983, Effects and role of estrogens in avian gonadal differentiation, Differentiation, 23, S87

10.1126/science.1734525

10.1002/jez.1123

10.1095/biolreprod.102.007294

10.1677/jme.0.0200193

10.1016/S0960-0760(96)00196-3

10.1002/(SICI)1098-2795(200001)55:1<20::AID-MRD4>3.0.CO;2-E

10.1006/gcen.1997.6978

10.1002/(SICI)1097-010X(19980801)281:5<362::AID-JEZ3>3.0.CO;2-M

10.1002/(SICI)1097-010X(19980801)281:5<373::AID-JEZ4>3.0.CO;2-L

10.1095/biolreprod65.2.613

10.1098/rstb.1970.0052

10.1210/me.2002-0055

10.1007/s004390051103

10.1002/aja.1001880411

10.1016/0092-8674(94)90251-8

10.1016/S0378-1119(99)00179-1

10.1073/pnas.86.10.3684

10.1016/0092-8674(94)90211-9

10.1016/0092-8674(93)90515-R

10.1038/35002622

10.1128/MCB.18.11.6653

10.1016/S0092-8674(00)81172-1

10.1006/gcen.1998.7214

10.1002/dvdy.10153

10.1016/S0092-8674(01)00453-6

10.1095/biolreprod.102.010884

10.1016/S0092-8674(01)00469-X

Kent J, 1995, The evolution of WT1 sequence and expression pattern in vertebrates, Oncogene, 11, 1781

10.1016/0016-6480(79)90187-4

10.1016/S0378-1119(99)00466-7

10.1677/jme.0.0240023

10.1210/en.2002-0095

10.1242/dev.122.9.2813

10.1002/(SICI)1097-0177(199903)214:3<171::AID-AJA1>3.0.CO;2-S

10.1002/(SICI)1097-0177(199808)212:4<522::AID-AJA5>3.0.CO;2-J

10.1002/(SICI)1097-0177(199912)216:4/5<411::AID-DVDY9>3.0.CO;2-Y

10.1016/S0960-9822(01)00070-7

10.1023/A:1011672227256

10.1038/45130

10.1006/dbio.1999.9461

10.1002/(SICI)1526-968X(200003)26:3<174::AID-GENE2>3.0.CO;2-J

10.1038/35618

10.1101/gad.834100

10.1016/S1567-133X(02)00071-6

10.1023/A:1009235120741

10.1007/s004270050310

10.1091/mbc.11.10.3645

10.1186/gb-2003-4-3-r18

10.1016/S0925-4773(02)00288-5

Etches RJ, 1997, Strategies for the production of transgenic chickens, Methods Mol Biol, 62, 433

10.1159/000016701

10.1016/S0091-679X(08)60629-9

10.1006/meth.1998.0595

10.1002/dvdy.10254

10.1038/nrg908

10.1038/ng944

10.1038/nbt770

10.1038/nrg998

Thông tin
Thông tin xuất bản

BioEssays

Tập 26 Số 2

120-132

Thông tin tác giả