Sex and age differences in COVID-19 mortality in Europe

Linda Juel Ahrenfeldt1, Martina Otavova1, Kaare Christensen1, Rune Lindahl-Jacobsen2
1Unit of Epidemiology, Biostatistics and Biodemography, Department of Public Health, University of Southern Denmark, J.B. Winsløws Vej 9B, 5000, Odense C, Denmark
2Interdisciplinary Center on Population Dynamics, University of Southern Denmark, 5000, Odense, Denmark

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Austad SN, Fischer KE. Sex differences in lifespan. Cell Metab. 2016;23(6):1022–33.

Barford A, Dorling D, Davey SG, Shaw M. Life expectancy: women now on top everywhere. BMJ. 2006;332(7545):808.

Zarulli V, Barthold Jones JA, Oksuzyan A, Lindahl-Jacobsen R, Christensen K, Vaupel JW. Women live longer than men even during severe famines and epidemics. Proc Natl Acad Sci U S A. 2018;115(4):E832–E40.

Guan WJ, Ni ZY, Hu Y, Liang WH, Ou CQ, He JX, et al. Clinical characteristics of coronavirus disease 2019 in China. N Engl J Med. 2020;382(18):1708–20.

JOHNS HOPKINS University & Medicine. Coronavirus resource center. 2020. https://coronavirus.jhu.edu/map.html. Accessed 27 June 2020.

Xie J, Tong Z, Guan X, Du B, Qiu H. Clinical characteristics of patients who died of coronavirus disease 2019 in China. JAMA Netw Open. 2020;3(4):e205619.

Jin JM, Bai P, He W, Wu F, Liu XF, Han DM, et al. Gender differences in patients with COVID-19: focus on severity and mortality. Front Public Health. 2020;8:152.

Dudley JP, Lee NT. Disparities in age-specific morbidity and mortality from SARS-coV‑2 in China and the republic of Korea. Clin Infect Dis. 2020;71(15):863–5. https://doi.org/10.1093/cid/ciaa354.

Qian J, Zhao L, Ye RZ, Li XJ, Liu YL. Age-dependent gender differences of COVID-19 in mainland China: comparative study. Clin Infect Dis. 2020;71(9):2488–94. https://doi.org/10.1093/cid/ciaa683.

Global Health 50/50. Sex, gender and COVID-19: overview and resources. 2020. https://globalhealth5050.org/covid19. Accessed 27 June 2020.

Gebhard C, Regitz-Zagrosek V, Neuhauser HK, Morgan R, Klein SL. Impact of sex and gender on COVID-19 outcomes in Europe. Biol Sex Differ. 2020;11(1):29.

Promislow DEL. A geroscience perspective on COVID-19 mortality. J Gerontol A Biol Sci Med Sci. 2020;75(9):e30–3. https://doi.org/10.1093/gerona/glaa094

Institut National D’Etudes Demographiques (INED) COVID-19. Demographics of COVID-19 deaths. 2020. https://dc-covid.site.ined.fr/en/data/. Accessed 30 June 2020.

Matsuyama R, Nishiura H, Kutsuna S, Hayakawa K, Ohmagari N. Clinical determinants of the severity of Middle East Respiratory Syndrome (MERS): a systematic review and meta-analysis. BMC Public Health. 2016;16(1):1203.

Karlberg J, Chong DS, Lai WY. Do men have a higher case fatality rate of severe acute respiratory syndrome than women do? Am J Epidemiol. 2004;159(3):229–31.

Leong HN, Earnest A, Lim HH, Chin CF, Tan C, Puhaindran ME, et al. SARS in Singapore—Predictors of disease severity. Ann Acad Med Singapore. 2006;35(5):326–31.

Alghamdi IG, Hussain II, Almalki SS, Alghamdi MS, Alghamdi MM, El-Sheemy MA. The pattern of Middle East respiratory syndrome coronavirus in Saudi Arabia: a descriptive epidemiological analysis of data from the Saudi Ministry of Health. Int J Gen Med. 2014;7:417–23.

Bartz D, Chitnis T, Kaiser UB, Rich-Edwards JW, Rexrode KM, Pennell PB, et al. Clinical advances in sex- and gender-informed medicine to improve the health of all: a review. JAMA Intern Med. 2020;180(4):574–83. https://doi.org/10.1001/jamainternmed.2019.7194.

Klein SL, Flanagan KL. Sex differences in immune responses. Nat Rev Immunol. 2016;16(10):626–38.

Sharma G, Volgman AS, Michos ED. Sex differences in mortality from COVID-19 pandemic: are men vulnerable and women protected? JaCC Case Rep. 2020;2(9):1407–10. https://doi.org/10.1016/j.jaccas.2020.04.027.

Ahrenfeldt LJ, Moller S, Thinggaard M, Christensen K, Lindahl-Jacobsen R. Sex differences in comorbidity and frailty in Europe. Int J Public Health. 2019;64(7):1025–36.

Scheel-Hincke LL, Möller S, Lindahl-Jacobsen R, Jeune B, Ahrenfeldt LJ. Cross-national comparison of sex differences in ADL and IADL in Europe: findings from SHARE. Eur J Ageing. 2020;17(1):69–79.

Case A, Paxson C. Sex differences in morbidity and mortality. Demography. 2005;42(2):189–214.

Whitacre CC. Sex differences in autoimmune disease. Nat Immunol. 2001;2(9):777–80.

Crimmins EM, Kim JK, Sole-Auro A. Gender differences in health: results from SHARE, ELSA and HRS. Eur J Public Health. 2011;21(1):81–91.

Salah HM, Mehta JL. Hypothesis: sex-related differences in ACE2 activity may contribute to higher mortality in men versus women with COVID-19. J Cardiovasc Pharmacol Ther. 2020;https://doi.org/10.1177/1074248420967792.

Ahrenfeldt LJ, Nielsen CR, Möller S, Christensen K, Lindahl-Jacobsen R. Burden and prevalence of risk factors for severe COVID-19 disease in the ageing European population—A SHARE-based analysis. Res Sq. 2020;https://doi.org/10.21203/rs.3.rs-73657/v1.

Walters V, McDonough P, Strohschein L. The influence of work, household structure, and social, personal and material resources on gender differences in health: an analysis of the 1994 Canadian National Population Health Survey. Soc Sci Med. 2002;54(5):677–92.

Ahrenfeldt LJ, Scheel-Hincke LL, Kjaergaard S, Moller S, Christensen K, Lindahl-Jacobsen R. Gender differences in cognitive function and grip strength: a cross-national comparison of four European regions. Eur J Public Health. 2019;29(4):667–74.

Emslie C, Hunt K, Macintyre S. Problematizing gender, work and health: the relationship between gender, occupational grade, working conditions and minor morbidity in full-time bank employees. Soc Sci Med. 1999;48(1):33–48.

Abate BB, Kassie AM, Kassaw MW, Aragie TG, Masresha SA. Sex difference in coronavirus disease (COVID-19): a systematic review and meta-analysis. BMJ Open. 2020;10(10):e40129.

Vardavas CI, Nikitara K. COVID-19 and smoking: a systematic review of the evidence. Tob Induc Dis. 2020;18:20.

Riahi M, Mohammadi AA, Rohani H, Bidkhori M. Dataset on the prevalence of tobacco smoking in men and women of selected countries whit difference human development. Data Brief. 2018;18:506–11.

Oksuzyan A, Juel K, Vaupel JW, Christensen K. Men: good health and high mortality. Sex differences in health and aging. Aging Clin Exp Res. 2008;20(2):91–102.

Grandi G, Facchinetti F, Bitzer J. The gendered impact of coronavirus disease (COVID-19): do estrogens play a role? Eur J Contracept Reprod Health Care. 2020;25(3):233–4. https://doi.org/10.1080/13625187.2020.1766017.